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https://www.readbyqxmd.com/read/28440981/-leading-causes-of-death-during-the-induction-therapy-in-pediatric-patients-with-acute-lymphoblastic-leukemia
#1
Máximo Aguilar-Hernández, Gabriela Fernández-Castillo, Nora Nancy Núñez-Villegas, Ruy Xavier Pérez-Casillas, Juan Carlos Núñez-Enríquez
BACKGROUND: Leukemias are the leading cause of childhood cancer. In most developed countries 1-2% of patients die during remission induction; however, in developing countries, this figure is higher and the causes of death apparently vary among the populations studied. The aim was to determine the cause of death during remission induction in pediatric patients with acute lymphoblastic leukemia (ALL) in the hospital "Dr. Gaudencio González Garza" of Centro Médico Nacional La Raza from January 1, 2009, to December 31, 2014...
May 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28439696/back-to-the-future-part-1-the-medico-legal-autopsy-from-ancient-civilization-to-the-post-genomic-era
#2
REVIEW
Giovanni Cecchetto, Thomas Bajanowski, Rossana Cecchi, Donata Favretto, Silke Grabherr, Takaki Ishikawa, Toshikazu Kondo, Massimo Montisci, Heidi Pfeiffer, Maurizio Rippa Bonati, Dina Shokry, Marielle Vennemann, Santo Davide Ferrara
Part 1 of the review "Back to the Future" examines the historical evolution of the medico-legal autopsy and microscopy techniques, from Ancient Civilization to the Post-Genomic Era. In the section focusing on "The Past", the study of historical sources concerning the origins and development of the medico-legal autopsy, from the Bronze Age until the Middle Ages, shows how, as early as 2000 BC, the performance of autopsies for medico-legal purposes was a known and widespread practice in some ancient civilizations in Egypt, the Far East and later in Europe...
April 24, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28438590/antibiotic-prophylaxis-in-cataract-surgery-in-the-setting-of-penicillin-allergy-a-decision-making-algorithm
#3
REVIEW
Benjamin R LaHood, Nicholas Andrew, Michael Goggin
Cataract surgery is the most commonly performed surgical procedure in many developed countries. Post-operative endophthalmitis is a rare complication with potentially devastating visual outcomes. Currently, there is no global consensus regarding antibiotic prophylaxis in cataract surgery despite growing evidence of the benefits of prophylactic intracameral cefuroxime at the conclusion of surgery. The decision about which antibiotic regimen to use is further complicated in patients reporting penicillin allergy...
April 21, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28438099/a-single-centre-review-of-suspected-sudden-infant-death-cases
#4
Janos Bokor, Krisztina Danics, Eszter Bencze, Eva Keller, Zoltan Szollosi
This study aimed to establish the number of deaths in infants under 1 year of age that were being reported for medico-legal examination at a single large academic centre in Hungary, as well as the method of these investigations with special emphasis on histopathology, ancillary techniques and the adherence of our current practice to international recommendations. A single-centre, retrospective audit was conducted on all suspected sudden infant death cases. After the review there were eight infectious background sudden infant death syndrome (SIDS) cases, infectious respiratory tract disease in 14 cases, cardiac septal tumour in one case, and hepatic, possibly metabolic, disorder in one case...
April 2017: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/28425888/-satisfa%C3%A3-%C3%A3-o-com-o-internato-m%C3%A3-dico-em-portugal
#5
Miguel Bigotte Vieira, Pedro Godinho, Nuno Gaibino, Raquel Dias, Agostinho Sousa, Inês Madanelo, Francisco Ribeiro-Mourão, Mariana Brandão, Sónia Duarte, Tiago Meirinhos, Ana Luísa Catarino, Cláudio Espírito Santo, Ricardo Caiado, Ricardo Marques, Ana Gonçalves Ferreira, Carlos Ramalheira, João Valente Jorge, Marta Losada, Mário Santos, Edson Oliveira, João Paulo Farias, José Manuel Silva
INTRODUCTION: In the last years, the global context of medical education and Medical Residency programs in Portugal suffered substantial changes. The primary objective of this study was to evaluate and characterize medical residents ́ satisfaction with medical residency programs in Portugal and to identify features that could be improved. MATERIAL AND METHODS: We utilized as model the survey Postgraduate Hospital Educational Environment Measure that has been developed in the United Kingdom and is speci cally targeted to medical residents...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28423747/establishment-of-requirements-and-methodology-for-the-development-and-implementation-of-greymatters-a-memory-clinic-information-system
#6
Archana Tapuria, Matt Evans, Vasa Curcin, Tony Austin, Nathan Lea, Dipak Kalra
INTRODUCTION: The aim of the paper is to establish the requirements and methodology for the development process of GreyMatters, a memory clinic system, outlining the conceptual, practical, technical and ethical challenges, and the experiences of capturing clinical and research oriented data along with the implementation of the system. METHODS: The methodology for development of the information system involved phases of requirements gathering, modeling and prototype creation, and 'bench testing' the prototype with experts...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28421634/vagus-nerve-stimulation-a-new-promising-therapeutic-tool-in-inflammatory-bowel-disease
#7
B Bonaz, V Sinniger, S Pellissier
Inflammatory bowel disease (IBD), that is Crohn's disease (CD) and ulcerative colitis, affects about 1.5 million persons in the USA and 2.2 million in Europe. The pathophysiology of IBD involves immunological, genetic and environmental factors. The treatment is medico-surgical but suspensive. Anti-TNFα agents have revolutionized the treatment of IBD but have side effects. In addition, a non-negligible percentage of patients with IBD stop or take episodically their treatment. Consequently, a nondrug therapy targeting TNFα through a physiological pathway, devoid of major side effects and with a good cost-effectiveness ratio, would be of interest...
April 18, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28420294/smart-recognising-the-value-of-existing-practice-and-introducing-recent-developments-leaving-no-stone-unturned-in-the-assessment-and-treatment-of-the-pdoc-patient
#8
H Gill-Thwaites, K E Elliott, R Munday
Over the last 25 years there have been a number of papers highlighting the issues of high rates of misdiagnosis in prolonged disorders of consciousness (PDOC) (Andrews, K., Murphy, L., Munday, R., & Littlewood, C. (1996). Misdiagnosis of the vegetative state: Retrospective study in a rehabilitation unit. BMJ, 313(7048), 13-16; Childs, N. L., Mercer, W. N., & Childs, H. W. (1993). Accuracy of diagnosis of persistent vegetative state. Neurology, 43(8), 1465-1467). Surprisingly, these rates still remain at the same level despite defined criteria for diagnosis (Schnakers, C...
April 18, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28418341/the-knowledge-level-and-opinions-of-physicians-about-the-medical-and-legal-procedures-related-to-physical-child-abuse
#9
Sema Demirçin, Akın Tütüncüler, Fatmagül Aslan, Sevtap Velipaşaoğlu Güney, Mehmet Atılgan, Hakan Gülkesen
BACKGROUND: In order to diagnose child abuse, physicians need to consider the possibility of abuse in every child they encounter, have sufficient information about the topic and manage the cases according to current law. AIMS: To determine the knowledge level of physicians on child abuse and to learn their opinions about the procedures when they suspect child abuse. STUDY DESIGN: A questionnaire (cross-sectional) study. METHODS: A detailed questionnaire was applied to 390 physicians of whom 233 were general practitioners...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28417050/venezuelan-surgeons-view-concerning-teaching-human-anatomical-dissection
#10
Rafael Romero-Reverón
Currently, the importance of human anatomical dissection have come under debate in many countries but there are not references in Venezuela on this concern. This survey's aim is to assess the insights of Venezuelan surgeons and their outlines of usage of human anatomical dissection in teaching and learning human anatomy. Sixty-five Venezuelan surgeons at the Centro Médico Docente La Trinidad completed an anonymous survey on current and future teaching practices in human anatomy. Eighty-nine point two three percent of surveyed (n=58) conferred importance to human anatomical dissection despite the arrival of new innovations in learning human anatomy...
March 2017: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/28413630/patient-healthcare-trajectory-an-essential-monitoring-tool-a-systematic-review
#11
REVIEW
Jessica Pinaire, Jérôme Azé, Sandra Bringay, Paul Landais
BACKGROUND: Patient healthcare trajectory is a recent emergent topic in the literature, encompassing broad concepts. However, the rationale for studying patients' trajectories, and how this trajectory concept is defined remains a public health challenge. Our research was focused on patients' trajectories based on disease management and care, while also considering medico-economic aspects of the associated management. We illustrated this concept with an example: a myocardial infarction (MI) occurring in a patient's hospital trajectory of care...
December 2017: Health Information Science and Systems
https://www.readbyqxmd.com/read/28407560/genital-and-anal-injuries-a-cross-sectional-australian-study-of-1266-women-alleging-recent-sexual-assault
#12
Renate R Zilkens, Debbie A Smith, Maureen A Phillips, S Aqif Mukhtar, James B Semmens, Maire C Kelly
OBJECTIVES: To describe the frequency of genital and anal injury and associated demographic and assault characteristics in women alleging sexual assault. DESIGN: Cross-sectional study. SETTING: Sexual Assault Resource Centre (SARC), Western Australia. PARTICIPANTS: Total of 1266 women attending SARC from Jan-2009 to Mar-2015. METHODS: Women underwent a standardised data collection procedure by forensically trained doctors...
March 29, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28403334/patient-safety-incidents-and-nursing-workload
#13
Katya Cuadros Carlesi, Kátia Grillo Padilha, Maria Cecília Toffoletto, Carlos Henriquez-Roldán, Monica Andrea Canales Juan
Objective: to identify the relationship between the workload of the nursing team and the occurrence of patient safety incidents linked to nursing care in a public hospital in Chile. Method: quantitative, analytical, cross-sectional research through review of medical records. The estimation of workload in Intensive Care Units (ICUs) was performed using the Therapeutic Interventions Scoring System (TISS-28) and for the other services, we used the nurse/patient and nursing assistant/patient ratios...
April 6, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28400041/heart-attack-guidance-for-physicians-when-to-suspect-how-to-diagnose-what-to-do
#14
EDITORIAL
K K Aggarwal, Sundeep Mishra
Lack of awareness among the first contact physicians is one of the major causes for delay in reperfusion therapy in India. Physicians need not only clear-cut guidance about when to perform an ECG and when to refer a patient but also need to understand the mortality advantage of early intervention as well as medico-legal aspects of this condition.
April 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28399467/ultrasound-assisted-low-density-solvent-dispersive-liquid-liquid-microextraction-for-the-determination-of-4-designer-benzodiazepines-in-urine-samples-by-gas-chromatography-triple-quadrupole-mass-spectrometry
#15
Liang Meng, Binling Zhu, Kefang Zheng, Shanlin Fu
A novel microextraction technique based on ultrasound-assisted low-density solvent dispersive liquid-liquid microextraction (UA-LDS-DLLME) had been applied for the determination of 4 designer benzodiazepines (phenazepam, diclazepam, flubromazepam and etizolam) in urine samples by gas chromatography- triple quadrupole mass spectrometry (GC-QQQ-MS). Ethyl acetate (168μL) was added into the urine samples after adjusting pH to 11.3. The samples were sonicated in an ultrasonic bath for 5.5min to form a cloudy suspension...
April 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28399461/measurement-of-open-apices-in-tooth-roots-in-colombian-children-as-a-tool-for-human-identification-in-asylum-and-criminal-proceedings
#16
REVIEW
Marcela Rivera, Stefano De Luca, Lina Aguilar, Luz Andrea Velandia Palacio, Ivan Galić, Roberto Cameriere
Dental age estimation was recognized as an imperative issue in clinical and medico-legal practice. However, very few studies on dental age estimation in children have been published in Colombia. This study evaluated the accuracy of Cameriere's method of measurement of open apices on tooth roots in a sample of 526 digital panoramic radiographs (OPTs) of children (274 boys and 252 girls), aged between 6 and 14 years, from Bogotá, Valle del Cauca, Buga and Villavicencio, in Southwest Colombia. Only first seven permanent lower teeth, except third molar, from the left side of mandible were studied...
April 6, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28399102/-the-social-pressing-of-self-destroyer-stigma-a-medic%C3%B0-sociological-study
#17
B S Polozhy, V A Ruzhenkov, V V Ruzhenkova
AIM: To explore the characteristics of social pressure of suicide-associated stigma for the development of preventive and destigmatization measures. MATERIAL AND METHODS: By the medico-sociological method were interviewed 1255 persons: 65 psychiatrists at the age of 23 to 80 years; 402 nurses and 437 ward attendants working in mental hospitals, and 351 people of the general population of the Belgorod region. RESULTS AND CONCLUSION: Significant differences were discovered in personal, intimate, family and other fields...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28390329/child-sexual-abuse-presenting-to-district-general-hospital-chilaw
#18
M D Chandrasiri, D K Wijewardena, S D Lanerolle, S E Chandrasiri, K P Wijewardena, R T Cooray
Introduction: Incidence of child sexual abuse is increasing worldwide. There is little data on child sexual abuse in the North Western Province of Sri Lanka. Objectives: To describe the demographic and medico-legal findings of victims of sexual abuse aged less than 16 years and to identify factors associated with positive findings on medical-legal examination. Methods: This cross-sectional analytical study, analysed 132 victims, referred by authorities to General Hospital,Chilaw, from 2012 to 2014...
March 31, 2017: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28390027/insects-associated-with-pig-carrion-in-two-environments-of-the-brazilian-savanna
#19
L S de Faria, M L Paseto, M S Couri, C A Mello-Patiu, J Mendes
Studies of carrion fauna have increased in Brazil and have contributed to the knowledge of this fauna in the national territory. Brazil has continental dimensions and presents various biomes in its territorial area. Most of the carrion fauna have seldom been studied, and this is especially true for the Savanna or "Cerrado." The present research examined the fauna visiting carrion in two environments and two seasons in a rural area situated in a region of Cerrado in southeastern Brazil. The two environments studied were a pasture and a fragment of semi-deciduous forest...
April 8, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28389908/validation-of-rem-score-to-predict-endometrial-cancer-in-patients-with-ultrasound-endometrial-abnormalities-results-of-a-new-independent-dataset
#20
Francesco Plotti, Stella Capriglione, Corrado Terranova, Roberto Montera, Giuseppe Scaletta, Salvatore Lopez, Daniela Luvero, Antonelli Gianina, Alessia Aloisi, Pierluigi Benedetti Panici, Roberto Angioli
The risk of endometrial malignancy (REM) score is a model formulated in a previous single-center validation study, which has been shown to predict endometrial cancer in women with ultrasound endometrial abnormalities based on multiple features (clinical, ultrasound and laboratorial). The purpose of this study was to validate the performance of REM score in an external validation setting. A population-based database with patients, who underwent elective hysteroscopy for ultrasound endometrial abnormalities between 2013 and 2016 at Department of Obstetrics and Gynecology of Campus Bio-medico of Rome, was used...
May 2017: Medical Oncology
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