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https://www.readbyqxmd.com/read/29474274/an-environmental-influences-on-child-health-outcomes-viewpoint-of-data-analysis-centers-for-collaborative-study-designs
#1
Lisa P Jacobson, Bryan Lau, Diane Catellier, Corette B Parker
PURPOSE OF REVIEW: A highly complex collaborative study design that pools and extends existing studies, such as the Environmental influences on Child Health Outcomes (ECHO) Program, requires a Data Analysis Center (DAC) with resources and expertise to create a secure environment for housing and analyzing the shared data, harmonize and structure the shared data for different purposes, and apply appropriate and innovative designs and analytic methods. The DAC, in partnership with cohort investigators, must ensure that results from ECHO-wide cohort analyses are appropriately interpreted and reproducible...
February 21, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29474210/the-potential-for-proactive-housing-inspections-to-inform-public-health-interventions
#2
Katrina Smith Korfmacher, Kathleen D Holt
Municipal housing inspection data can inform planning, targeting, and evaluating interventions aimed at reducing housing hazards (lead paint, mold, pests, etc) that may affect residents' health. However, the potential of these data to inform public health initiatives is underexplored. We determined whether home health hazards identified by city inspectors during proactive inspections of single-family private rental housing are predicted by housing age, assessed value, or location in one of 26 geographic "inspector areas" in Rochester, New York...
February 22, 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29473902/advances-in-residential-design-related-to-the-influence-of-geomagnetism
#3
Francisco Glaria, Israel Arnedo, Ana Sánchez-Ostiz
Since the origin of the Modern Movement, there has been a basic commitment to improving housing conditions and the well-being of occupants, especially given the prediction that 2/3 of humanity will reside in cities by 2050. Moreover, a compact model of the city with tall buildings and urban densification at this scale will be generated. Continuous constructive and technological advances have developed solid foundations on safety, energy efficiency, habitability, and sustainability in housing design. However, studies on improving the quality of life in these areas continue to be a challenge for architects and engineers...
February 23, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29473487/new-design-development-and-optimization-of-an-in-house-quantitative-taqman-real-time-pcr-assay-for-hiv-1-viral-load-measurement
#4
Hassan Noorbazargan, Seyed Alireza Nadji, Siamak Mirab Samiee, Mahdi Paryan, Samira Mohammadi-Yeganeh
Background Viral load measurement is commonly applicable to monitor HIV infection in patients to determine the number of HIV-RNA in serum samples of individuals. The aim of the present study was to set up a highly specific, sensitive, and reproducible home-brewed Real-time PCR assay based on TaqMan chemistry to quantify HIV-1 RNA genome. Methods In this study, three sets of primer pairs and a TaqMan probe were designed for HIV subtypes conserved sequences. An internal control was included in this assay to evaluate the presence of inhibition...
February 23, 2018: HIV Clinical Trials
https://www.readbyqxmd.com/read/29473485/high-virologic-failure-rates-with-maraviroc-based-salvage-regimens-among-indian-patients-a-preliminary-analysis-maraviroc-effectiveness-in-hiv-1-subtype-c
#5
Sanjay Pujari, Sunil Gaikwad, Vivek Bele, Kedar Joshi, Digamber Dabhade
BACKGROUND: There is no information on the clinical effectiveness of Maraviroc (MVC) amongst People Living with HIV (PLHIV) in India infected with HIV-1 Subtype C viruses. METHODS: We conducted a retrospective chart review of adult PLHIV on MVC based Antiretroviral (ARV) regimens for at least 6 months. Maraviroc was initiated amongst PLHIV with documented R5 tropic viruses (determined by in-house population sequencing of the V3 loop in triplicate and interpreted using the Geno2Pheno algorithm) in combination with an Optimized Background regimen (designed using genotypic resistance testing and past ARV history)...
January 2018: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29471545/high-protein-distillers-dried-grains-with-solubles-produced-using-a-novel-front-end-back-end-fractionation-technology-has-greater-nutritional-value-than-conventional-distillers-dried-grains-with-solubles-when-fed-to-growing-pigs
#6
C D Espinosa, H H Stein
Two experiments were conducted to determine the standardized ileal digestibility (SID) of CP and AA, apparent total tract digestibility (ATTD) of GE, and DE and ME in conventional distillers dried grains with solubles (DDGS-CV) and in a novel source of high-protein distillers dried grains with solubles (DDGS-HP) produced by Lincolnway Energy (Nevada, IA). In Exp. 1, 18 barrows (initial BW: 72.47 ± 9.16 kg) that had a T-cannula installed in the distal ileum were allotted to a completely randomized design with 3 diets and 6 replicate pigs per diet...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471412/interactions-between-the-concentration-of-non-starch-polysaccharides-in-wheat-and-the-addition-of-an-enzyme-mixture-in-a-broiler-digestibility-and-performance-trial
#7
N Smeets, F Nuyens, L Van Campenhout, E Delezie, T A Niewold
Two broiler trials were designed to investigate the relationship between the concentration of non-starch polysaccharides (NSP) in wheat and 1) its nutritional value for broilers and 2) the efficacy of exogenous enzymes. In a balance trial, diets were formulated with 3 wheat cultivars (Rustic and Viscount-medium NSP, Centenaire-high NSP) and were tested with or without the addition of an exogenous enzyme mixture. The diets were fed to 144 male Ross 308 broiler chickens housed in digestibility cages. Total tract nutrient digestibilities and AMEn were measured from 18 to 22 d of age...
February 16, 2018: Poultry Science
https://www.readbyqxmd.com/read/29468636/oxidation-catalysis-by-iron-and-manganese-porphyrins-within-enzyme-like-cages
#8
REVIEW
Marco Chino, Linda Leone, Gerardo Zambrano, Fabio Pirro, Daniele D'Alonzo, Vincenzo Firpo, Diaa Aref, Liliana Lista, Ornella Maglio, Flavia Nastri, Angela Lombardi
Inspired by natural heme-proteins, scientists have attempted for decades to design efficient and selective metalloporphyrin-based oxidation catalysts. Starting from the pioneering work on small molecule mimics in the late 1970s, we have assisted to a tremendous progress in designing cages of different nature and complexity, able to accommodate metalloporphyrins. With the intent of tuning and controlling their reactivity, more and more sophisticated and diverse environments are continuously exploited. In this review, we will survey the current state of art in oxidation catalysis using iron- and manganese-porphyrins housed within designed or engineered protein cages...
February 22, 2018: Biopolymers
https://www.readbyqxmd.com/read/29466464/factors-that-enable-or-limit-the-sustained-use-of-improved-firewood-cookstoves-qualitative-findings-eight-years-after-an-intervention-in-rural-mexico
#9
Minerva Catalán-Vázquez, Rosario Fernández-Plata, David Martínez-Briseño, Blanca Pelcastre-Villafuerte, Horacio Riojas-Rodríguez, Laura Suárez-González, Rogelio Pérez-Padilla, Astrid Schilmann
OBJECTIVE: The aim of this study was to analyze the factors enabling/limiting the use of improved cookstoves among rural fuel wood users from one mestizo and two indigenous communities eight years after an intervention in the state of Michoacan, in Mexico. METHODS: A qualitative study with an ethnographic perspective was conducted in 2013/2014 based on 62 interviews with women who had participated in an improved firewood cookstove program in 2005. Thematic qualitative content analysis was performed...
2018: PloS One
https://www.readbyqxmd.com/read/29466450/inclusion-of-live-yeast-and-mannan-oligosaccharides-in-high-grain-based-diets-for-sheep-ruminal-parameters-inflammatory-response-and-rumen-morphology
#10
Tatiana Garcia Diaz, Antonio Ferriani Branco, Fernando Alberto Jacovaci, Clóves Cabreira Jobim, Dheyme Cristina Bolson, João Luiz Pratti Daniel
The objective of this study was to evaluate the effects of dietary supplementation with live yeast (Saccharomyces cerevisiae), mannan-oligosaccharides and the combination of these additives on the inflammatory response, ruminal parameters and rumen morphology of sheep fed a high grain-based diet. Thirty-Two Dorper x Santa Ines crossbred lambs with an average weight of 24±2 kg were distributed in a completely randomized design. The animals were housed in individual stalls and fed ad libitum. Diet treatments were: Control (without additive); LY (2 g/kg DM of live yeast, Saccharomyces cerevisiae), MOS (2 g/kg DM of mannan-oligosaccharides) and LY+MOS (2 g/kg DM of LY + 2 g/kg DM of MOS)...
2018: PloS One
https://www.readbyqxmd.com/read/29466230/linkage-of-1999-2012-national-health-interview-survey-and-national-health-and-nutrition-examination-survey-data-to-u-s-department-of-housing-and-urban-development-administrative-records
#11
Patricia C Lloyd, Veronica E Helms, Alan E Simon, Cordell Golden, James Brittain, Eileen Call, Lisa B Mirel, Barry L Steffen, Jon Sperling, Elizabeth C Rudd, Jennifer D Parker, Carol S Star
Objectives This report presents the development, plan, and operation of the 2011-2012 National Survey of Children's Health, a module of the State and Local Area Integrated Telephone Survey, conducted by the National Center for Health Statistics. Funding was provided by the Maternal and Child Health Bureau, Health Resources and Services Administration. The survey was designed to produce national and state prevalence estimates of the physical and emotional health of children aged 0-17 years, as well as factors that may relate to child well-being including medical homes, family interactions, parental health, school and after-school experiences, and neighborhood characteristics...
October 2017: Vital and Health Statistics. Ser. 1, Programs and Collection Procedures
https://www.readbyqxmd.com/read/29464542/streptomyces-tunisialbus-sp-nov-a-novel-streptomyces-species-with-antimicrobial-activity
#12
Ameni Ayed, Nedra Slama, Houda Mankai, Sarra Bachkouel, Salem ElKahoui, Olfa Tabbene, Ferid Limam
A novel actinomycete strain designated S2T was isolated from Tunisian rhizosphere soil of Lavandula officinalis. This isolate exhibited broad spectrum antibacterial activity against several Gram-positive and Gram-negative bacteria and also antifungal activity against yeast and filamentous fungi. The isolate S2T presents morphological and chemotaxonomic characteristics typical of the members of the genus Streptomyces. Whole cell hydrolysates of S2T were found to contain LL-diaminopimelic acid. The major fatty acids were identified as C16:0, anteiso-C15:0 and iso-C16:0 whereas the predominant menaquinones were found to be MK-9(H6) and MK-9(H8)...
February 20, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29464460/effects-of-hollow-fiber-membrane-oscillation-on-an-artificial-lung
#13
Ryan A Orizondo, Guy Gino, Garret Sultzbach, Shalv P Madhani, Brian J Frankowski, William J Federspiel
Gas transfer through hollow fiber membranes (HFMs) can be increased via fiber oscillation. Prior work, however, does not directly translate to present-day, full-scale artificial lungs. This in vitro study characterized the effects of HFM oscillations on oxygenation and hemolysis for a pediatric-sized HFM bundle. Effects of oscillation stroke length (2-10 mm) and frequency (1-25 Hz) on oxygen transfer were measured according to established standards. The normalized index of hemolysis was measured for select conditions...
February 20, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29462361/wet-feed-and-cold-water-as-heat-stress-modulators-in-growing-muscovy-ducklings
#14
M F A Farghly, M E Abd El-Hack, M Alagawany, I M Saadeldin, A A Swelum
In an attempt to alleviate the deleterious effects of high summer temperatures, the present study investigated the effects of wet feed and cold water on the growth performance, carcass and meat quality, leg problems, physiological responses, and blood parameters of growing Muscovy ducklings. A total of 180 4-week-old ducklings was randomly divided into 6 experimental groups in a 3 × 2 factorial design that included 3 feed systems (AD: ad libitum dry; DW: diurnal wet; and AW: ad libitum wet) and 2 systems of water (TW: tap water; and CW: cold water)...
February 14, 2018: Poultry Science
https://www.readbyqxmd.com/read/29462292/state-and-non-state-mental-health-service-collaboration-in-a-south-african-district-a-mixed-methods-study
#15
André Janse van Rensburg, Inge Petersen, Edwin Wouters, Michelle Engelbrecht, Gladys Kigozi, Pieter Fourie, Dingie van Rensburg, Piet Bracke
The Life Esidimeni tragedy in South Africa showed that, despite significant global gains in recognizing the salience of integrated public mental health care during the past decade, crucial gaps remain. State and non-state mental health service collaboration is a recognized strategy to increase access to care and optimal use of community resources, but little evidence exist about how it unfolds in low- to middle-income countries. South Africa's Mental Health Policy Framework and Strategic Plan 2013-20 (MHPF) underlines the importance of collaborative public mental health care, though it is unclear how and to what extent this happens...
February 15, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29459494/a-dual-mode-hemispherical-sparse-array-for-three-dimensional-passive-acoustic-mapping-and-skull-localization-within-a-clinical-mri-guided-focused-ultrasound-device
#16
Calum Crake, Spencer T Brinker, Christian M Coviello, Margaret Livingstone, Nathan J McDannold
Previous work has demonstrated that passive acoustic imaging may be used alongside MRI for monitoring of focused ultrasound therapy. However, past implementations have generally made use of either linear arrays originally designed for diagnostic imaging or custom narrowband arrays specific to in-house therapeutic transducer designs, neither of which is fully compatible with clinical MR-guided focused ultrasound devices. Here we have designed an array which is suitable for use within an FDA-approved MR-guided transcranial focused ultrasound device, within the bore of a 3 Tesla clinical MRI scanner...
February 20, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29458332/identification-of-genetic-variants-for-clinical-management-of-familial-colorectal-tumors
#17
Mev Dominguez-Valentin, Sigve Nakken, Hélène Tubeuf, Daniel Vodak, Per Olaf Ekstrøm, Anke M Nissen, Monika Morak, Elke Holinski-Feder, Alexandra Martins, Pål Møller, Eivind Hovig
BACKGROUND: The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed to study the potential contribution of genes other than MMR genes to the biological and clinical characteristics of Norwegian families fulfilling Amsterdam (AMS) criteria or revised Bethesda guidelines. METHODS: The Hereditary Cancer Biobank of the Norwegian Radium Hospital was interrogated to identify individuals with a high risk of developing colorectal cancer (CRC) for whom no pathogenic variants in MMR genes had been found in routine diagnostic DNA sequencing...
February 20, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29455722/computer-assisted-motivational-interviewing-intervention-to-facilitate-teen-pregnancy-prevention-and-fitness-behavior-changes-a-randomized-trial-for-young-men
#18
David L Bell, Samantha Garbers, Marina Catallozzi, R Stanley Hum, Meredith Nechitilo, Ian W McKeague, Emilia H Koumans, L Duane House, Susan L Rosenthal, Melanie A Gold
PURPOSE: Despite recent declines, teen unintended pregnancy and sexually transmitted infections in the United States remain at levels higher than comparable nations. Initiatives to prevent teen pregnancy have focused primarily on female adolescents; how to effectively engage young men to reduce their risk of fathering a teen pregnancy has not been well studied. We proposed to adapt an innovative computer-assisted motivational interviewing (CAMI) intervention, originally designed and tested with young women, for use with young men, aged 15-24 years, to reduce their risk of fathering a teen pregnancy...
March 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29455428/potential-of-feeding-beef-cattle-with-whole-corn-crop-silage-and-rice-straw-in-malaysia
#19
Muhamad Hazim Nazli, Ridzwan Abdul Halim, Amin Mahir Abdullah, Ghazali Hussin, Anjas Asmara Samsudin
The potential of using whole corn crop silage and rice straw as an alternative feed for the beef cattle based on the intake and growth performance were evaluated. Using randomised completely block design, nine adult Mafriwal cattle were blocked intro three groups and treated with three different forage diets supplemented with 20% pelleted palm kernel cake on dry matter basis. The treatments were 100% rice straw (RS), 100% corn silage (CS) and an equal mixture of rice straw and corn silage (MIX) fed ad libitum...
February 17, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29453107/body-fluid-identification-using-a-targeted-mrna-massively-parallel-sequencing-approach-results-of-a-euroforgen-ednap-collaborative-exercise
#20
S Ingold, G Dørum, E Hanson, A Berti, W Branicki, P Brito, P Elsmore, K B Gettings, F Giangasparo, T E Gross, S Hansen, E N Hanssen, M-L Kampmann, M Kayser, F-X Laurent, N Morling, A Mosquera-Miguel, W Parson, C Phillips, M J Porto, E Pośpiech, A D Roeder, P M Schneider, K Schulze Johann, C R Steffen, D Syndercombe-Court, M Trautmann, M van den Berge, K J van der Gaag, J Vannier, V Verdoliva, A Vidaki, C Xavier, J Ballantyne, C Haas
In a previous study we presented an assay for targeted mRNA sequencing for the identification of human body fluids, optimised for the Illumina MiSeq/FGx MPS platform. This assay, together with an additional in-house designed assay for the Ion Torrent PGM/S5 platform, was the basis for a collaborative exercise within 17 EUROFORGEN and EDNAP laboratories, in order to test the efficacy of targeted mRNA sequencing to identify body fluids. The task was to analyse the supplied dried body fluid stains and, optionally, participants' own bona fide or mock casework samples of human origin, according to specified protocols...
January 31, 2018: Forensic Science International. Genetics
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