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Cardiovascular magnetic resonance CMR

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https://www.readbyqxmd.com/read/29136120/t2-mapping-cardiovascular-magnetic-resonance-identifies-the-presence-of-myocardial-inflammation-in-patients-with-dilated-cardiomyopathy-as-compared-to-endomyocardial-biopsy
#1
M Spieker, E Katsianos, M Gastl, P Behm, P Horn, C Jacoby, B Schnackenburg, P Reinecke, M Kelm, R Westenfeld, F Bönner
Aims: The aim of this study was to determine the value of T2 mapping for the non-invasive assessment of myocardial inflammation in different stages of systolic left ventricular dysfunction in dilated cardiomyopathy (DCM) in comparison with endomyocardial biopsy (EMB). Methods and results: A total of 132 subjects were enrolled between 2013 and 2016 (62 controls and 70 patients with DCM). All patients underwent CMR at 1.5 T and received coronary angiogram and EMB...
November 10, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29133275/normal-values-for-myocardial-deformation-within-the-right-heart-measured-by-feature-tracking-cardiovascular-magnetic-resonance-imaging
#2
Boyang Liu, Ahmed M Dardeer, William E Moody, Nicola C Edwards, Lucy E Hudsmith, Richard P Steeds
BACKGROUND: Reproducible and repeatable assessment of right heart function is vital for monitoring congenital and acquired heart disease. There is increasing evidence for the additional value of myocardial deformation (strain and strain rate) in determining prognosis. This study aims to determine the reproducibility of deformation analyses in the right heart using cardiovascular magnetic resonance feature tracking (FT-CMR); and to establish normal ranges within an adult population. METHODS: A cohort of 100 healthy subjects containing 10 males and 10 females from each decade of life between the ages of 20 and 70 without known congenital or acquired cardiovascular disease, hypertension, diabetes, dyslipidaemia or renal, hepatic, haematologic and systemic inflammatory disorders underwent FT-CMR assessment of right ventricular (RV) and right atrial (RA) myocardial strain and strain rate...
October 31, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29132649/doppler-versus-thermodilution-derived-coronary-microvascular-resistance-to-predict-coronary-microvascular-dysfunction-in-patients-with-acute-myocardial-infarction-or-stable-angina-pectoris
#3
Rupert P Williams, Guus A de Waard, Kalpa De Silva, Matthew Lumley, Kaleab Asrress, Satpal Arri, Howard Ellis, Awais Mir, Brian Clapp, Amedeo Chiribiri, Sven Plein, Paul F Teunissen, Maurits R Hollander, Michael Marber, Simon Redwood, Niels van Royen, Divaka Perera
Coronary microvascular resistance is increasingly measured as a predictor of clinical outcomes, but there is no accepted gold-standard measurement. We compared the diagnostic accuracy of 2 invasive indices of microvascular resistance, Doppler-derived hyperemic microvascular resistance (hMR) and thermodilution-derived index of microcirculatory resistance (IMR), at predicting microvascular dysfunction. A total of 54 patients (61 ± 10 years) who underwent cardiac catheterization for stable coronary artery disease (n = 10) or acute myocardial infarction (n = 44) had simultaneous intracoronary pressure, Doppler flow velocity and thermodilution flow data acquired from 74 unobstructed vessels, at rest and during hyperemia...
October 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29122140/cardiac-tissue-characterization-and-imaging-in-autoimmune-rheumatic-diseases
#4
REVIEW
Sophie I Mavrogeni, Petros P Sfikakis, Loukia Koutsogeorgopoulou, George Markousis-Mavrogenis, Theodoros Dimitroulas, Genovefa Kolovou, George D Kitas
Inflammation, microvascular and macrovascular ischemia, valvular disease, and fibrosis are the main causes of cardiovascular disease (CVD) in autoimmune rheumatic diseases (ARDs). The silent presentation and the high mortality and/or morbidity of CVD in ARDs necessitate a reliable tool for early diagnosis. Noninvasive cardiovascular imaging, including echocardiography, nuclear imaging, cardiovascular computed tomography (CT), cardiac magnetic resonance (CMR), and hybrid imaging modalities, constitutes the main tool for monitoring of CVD in ARDs...
November 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29121956/regional-differences-in-prognostic-value-of-cardiac-valve-plane-displacement-in-systemic-light-chain-amyloidosis
#5
Marco M Ochs, Thomas Fritz, Nisha Arenja, Johannes Riffel, Florian Andre, Derliz Mereles, Fabian Aus dem Siepen, Ute Hegenbart, Stefan Schönland, Hugo A Katus, Matthias G W Friedrich, Sebastian J Buss
BACKGROUND: To compare the prognostic value of cardiac valve plane displacement (CVPD) on various locations in cardiac light chain (AL) amyloidosis. METHODS: Consecutive patients with biopsy-proven cardiac involvement in AL amyloidosis who had undergone cardiovascular magnetic resonance (CMR) between 2005 and 2014 in our institution, were retrospectively identified and data analyzed. The primary combined endpoint was all-cause mortality or heart transplantation...
November 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29121751/prognostic-implications-of-global-myocardial-mechanics-in-hypertrophic-cardiomyopathy-by-cardiovascular-magnetic-resonance-feature-tracking-relations-to-left-ventricular-hypertrophy-and-fibrosis
#6
Rocio Hinojar, Covadonga Fernández-Golfín, Ariana González-Gómez, Luis Miguel Rincón, Maria Plaza-Martin, Eduardo Casas, Ana García-Martín, Mª Angeles Fernandez-Mendez, Amparo Esteban, Jose Julio Jimenez Nacher, Jose Luis Zamorano
BACKGROUND: Interstitial fibrosis, myocardial fiber disarray and non-uniform shortening are common histological features of hypertrophic cardiomyopathy (HCM). The degree of LV hypertrophy and fibrosis are postulated to contribute to the impairment of myocardial shortening. Cardiovascular magnetic resonance myocardial (CMR) feature tracking (CMR-FT) has emerged as a robust method that provides quantitative measurements of myocardial deformation. Our aim was first to evaluate LV strain parameters in HCM by CMR-FT and their dependence on both functional parameters and late gadolinium enhancement (LGE); and secondly we sought to determine their association with major cardiovascular outcomes...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29119274/quantification-of-pulmonary-regurgitation-and-prediction-of-pulmonary-valve-replacement-by-echocardiography-in-patients-with-congenital-heart-defects-in-comparison-to-cardiac-magnetic-resonance-imaging
#7
Claudia Dellas, Laura Kammerer, Verena Gravenhorst, Joachim Lotz, Thomas Paul, Michael Steinmetz
Pulmonary regurgitation (PR) is common in patients with congenital heart defects (CHD) and contributes to morbidity and mortality in the long-term. We investigated in this retrospective analysis whether readily accessible echocardiographic parameters are useful for quantification of PR and for predicting pulmonary valve replacement (PVR) in comparison to the gold-standard phase contrast (PC) flow measurements from cardiovascular magnetic resonance (CMR). Continuous wave (CW) Doppler and colour flow images in echocardiograms from 53 patients with CHD were analysed...
November 8, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29119262/role-of-cardiac-pet-in-clinical-practice
#8
REVIEW
Brian M Salata, Parmanand Singh
Early identification of atherosclerosis and at-risk lesions plays a critical role in reducing the burden of cardiovascular disease. While invasive coronary angiography serves as the gold standard for diagnosing coronary artery disease, non-invasive imaging techniques provide visualization of both anatomical and functional atherosclerotic processes prior to clinical presentation. The development of cardiac positron emission tomography (PET) has greatly enhanced our capability to diagnose and treat patients with early stages of atherosclerosis...
November 9, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29117866/ambulatory-systolic-blood-pressure-and-obesity-are-independently-associated-with-left-ventricular-hypertrophic-remodeling-in-children
#9
Linyuan Jing, Christopher D Nevius, Cassi M Friday, Jonathan D Suever, Arichanah Pulenthiran, Abba Mejia-Spiegeler, H Lester Kirchner, William J Cochran, Gregory J Wehner, Aftab S Chishti, Christopher M Haggerty, Brandon K Fornwalt
BACKGROUND: Children with obesity have hypertrophic cardiac remodeling. Hypertension is common in pediatric obesity, and may independently contribute to hypertrophy. We hypothesized that both the degree of obesity and ambulatory blood pressure (ABP) would independently associate with measures of hypertrophic cardiac remodeling in children. METHODS: Children, aged 8-17 years, prospectively underwent cardiovascular magnetic resonance (CMR) and ABP monitoring. Left ventricular (LV) mass indexed to height(2...
November 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29116176/redefining-viability-by-cardiovascular-magnetic-resonance-in-acute-st-segment-elevation-myocardial-infarction
#10
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Daniel S Knight, Sabrina Nordin, Alex Sirker, Anna S Herrey, Charlotte Manisty, James C Moon, Derek J Hausenloy
In chronic myocardial infarction (MI), segments with a transmural extent of infarct (TEI) of ≤50% are defined as being viable. However, in the acute phase of an ST-segment elevation myocardial infarction (STEMI), late gadolinium enhancement (LGE) has been demonstrated to overestimate MI size and TEI. We aimed to identify the optimal cut-off of TEI by cardiovascular magnetic resonance (CMR) for defining viability during the acute phase of an MI, using ≤50% TEI at follow-up as the reference standard. 40 STEMI patients reperfused by primary percutaneous coronary intervention (PPCI) underwent a CMR at 4 ± 2 days and 5 ± 2 months...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29110679/high-throughput-gadobutrol-enhanced-cmr-a-time-and-dose-optimization-study
#11
Tommaso D'Angelo, Chrysanthos Grigoratos, Silvio Mazziotti, Konstantinos Bratis, Faraz Pathan, Alfredo Blandino, Elen Elen, Valentina O Puntmann, Eike Nagel
BACKGROUND: Reducing time and contrast agent doses are important goals to provide cost-efficient cardiovascular magnetic resonance (CMR) imaging. Limited information is available regarding the feasibility of evaluating left ventricular (LV) function after gadobutrol injection as well as defining the lowest dose for high quality scar imaging. We sought to evaluate both aspects separately and systematically to provide an optimized protocol for contrast-enhanced CMR (CE-CMR) using gadobutrol...
November 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29110669/a-comparison-of-cardiovascular-magnetic-resonance-and-single-photon-emission-computed-tomography-spect-perfusion-imaging-in-left-main-stem-or-equivalent-coronary-artery-disease-a-ce-marc-substudy
#12
James R J Foley, Ananth Kidambi, John D Biglands, Neil Maredia, Catherine J Dickinson, Sven Plein, John P Greenwood
BACKGROUND: Assessment of left main stem (LMS) stenosis has prognostic and therapeutic implications. Data on assessment of LMS disease by cardiovascular magnetic resonance (CMR) and single photon emission computed tomography (SPECT) are limited. CE-MARC is the largest prospective comparison of CMR and SPECT against quantitative invasive coronary angiography (QCA) for detection of coronary artery disease (CAD), and provided the framework for this evaluation. The aims of this study were to compare diagnostic accuracy of visual and quantitative perfusion CMR to SPECT in patients with LMS stable CAD...
November 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29107357/late-gadolinium-enhancement-as-a-predictor-of-functional-recovery-need-for-defibrillator-implantation-and-prognosis-in-non-ischemic-dilated-cardiomyopathy
#13
Andrea Barison, Alberto Aimo, Alessandro Ortalda, Giancarlo Todiere, Chrysanthos Grigoratos, Claudio Passino, Paolo G Camici, Giovanni D Aquaro, Michele Emdin
BACKGROUND: Aim of the study was to investigate whether late gadolinium enhancement (LGE) at cardiac magnetic resonance (CMR) predict reverse remodeling (RR) in non-ischemic dilated cardiomyopathy (NIDCM). METHODS: Seventy-one NIDCM patients (age 57±14years, 43 males, median left ventricular ejection fraction [LVEF] 35%, [interquartile range 27-41%]) with two CMR scans within 5years were included. RR was defined as ≥10% reduction in left ventricular (LV) end-diastolic volume and ≥10% LVEF increase...
October 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29104737/cardiac-magnetic-resonance-imaging-which-information-is-useful-for-the-arrhythmologist
#14
REVIEW
Elia De Maria, Annachiara Aldrovandi, Ambra Borghi, Letizia Modonesi, Stefano Cappelli
Cardiac magnetic resonance (CMR) is a non-invasive, non-ionizing, diagnostic technique that uses magnetic fields, radio waves and field gradients to generate images with high spatial and temporal resolution. After administration of contrast media (e.g., gadolinium chelate), it is also possible to acquire late images, which make possible the identification and quantification of myocardial areas with scar/fibrosis (late gadolinium enhancement, LGE). CMR is currently a useful instrument in clinical cardiovascular practice for the assessment of several pathological conditions, including ischemic and non-ischemic cardiomyopathies and congenital heart disease...
October 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29098524/mechanical-dyssynchrony-alters-left-ventricular-flow-energetics-in-failing-hearts-with-lbbb-a-4d-flow-cmr-pilot-study
#15
Jakub Zajac, Jonatan Eriksson, Urban Alehagen, Tino Ebbers, Ann F Bolger, Carl-Johan Carlhäll
The impact of left bundle branch block (LBBB) related mechanical dyssynchrony on left ventricular (LV) diastolic function remains unclear. 4D flow cardiovascular magnetic resonance (CMR) has provided reliable markers of LV dysfunction: reduced volume and kinetic energy (KE) of the portion of LV inflow which passes directly to outflow (Direct Flow) has been demonstrated in failing hearts compared to normal hearts. We sought to investigate the impact of mechanical dyssynchrony on diastolic function by comparing 4D flow in myopathic LVs with and without LBBB...
November 2, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29098349/vortex-flow-in-the-right-atrium-surrogates-supraventricular-arrhythmia-and-thrombus-after-atriopulmonary-connection-type-fontan-operation-vortex-flow-analysis-using-conventional-cine-magnetic-resonance-imaging
#16
Yumi Shiina, Kei Inai, Tatsunori Takahashi, Yamato Shimomiya, Umiko Ishizaki, Kenji Fukushima, Michinobu Nagao
We developed a novel imaging technique, designated as vortex flow (VF) mapping, which presents a vortex flow visually on conventional two-dimensional (2D) cine MRI. Using it, we assessed circumferential VF patterns and influences on RA thrombus and supraventricular tachycardia (SVT) in AP connection-type Fontan circulation. Retrospectively, we enrolled 27 consecutive patients (25.1 ± 9.2 years) and 7 age-matched controls who underwent cardiac MRI. Conventional cine images acquired using a 1.5-Tesla scanner were scanned for axial and coronal cross section of the RA...
November 2, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29071521/cmr-assessment-and-clinical-outcomes-of-hypertrophic-cardiomyopathy-with-or-without-ventricular-remodeling-in-the-end-stage-phase
#17
Sainan Cheng, Yeon Hyeon Choe, Hideki Ota, Chen Cui, Gang Yin, Minjie Lu, Lu Li, Xiuyu Chen, Sanjay K Prasad, Shihua Zhao
End-stage phase of hypertrophic cardiomyopathy (ES-HCM) is a recognized part of HCM disease spectrum. Information on cardiac magnetic resonance (CMR) studies for ES-HCM especially for those without ventricular remodeling has been limited. We aimed to evaluate the morpho-functional and tissue features of ES-HCM with or without ventricular remodeling and to explore CMR prognostic value in these patients. We analysed CMR scans of sixty-three ES-HCM patients and divided them into those with ventricular dilatation (D-ES, n = 41) and those with normal ventricular size (N-ES, n = 22)...
October 25, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29070834/myocardial-changes-in-incident-haemodialysis-patients-over-6-months-an-observational-cardiac-magnetic-resonance-imaging-study
#18
Elaine Rutherford, Kenneth Mangion, Christie McComb, Elizabeth Bell, Samantha Cockburn, Mohammed Talle, Giles Roditi, Paul Welsh, Rosemary Woodward, Aleksandra Radjenovic, Allan D Struthers, Alan G Jardine, Colin Berry, Rajan K Patel, Patrick B Mark
Patients commencing on haemodialysis (HD) have an increased risk of cardiovascular events in the first year after starting HD compared to those patients established on HD longer. Left ventricular (LV) hypertrophy and abnormal myocardial strain predict mortality. There may be changes in the myocardium of incident HD patients over a 6-month period of HD which may explain changes in cardiovascular risk. We used CMR to consider changes in LV mass, myocardial strain and T1 mapping. We examined changes in pre-dialysis highly sensitive troponin T...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29070069/adenosine-stress-cmr-t1-mapping-detects-early-microvascular-dysfunction-in-patients-with-type-2-diabetes-mellitus-without-obstructive-coronary-artery-disease
#19
Eylem Levelt, Stefan K Piechnik, Alexander Liu, Rohan S Wijesurendra, Masliza Mahmod, Rina Ariga, Jane M Francis, Andreas Greiser, Kieran Clarke, Stefan Neubauer, Vanessa M Ferreira, Theodoros D Karamitsos
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with coronary microvascular dysfunction in the absence of obstructive coronary artery disease (CAD). Cardiovascular magnetic resonance (CMR) T1-mapping at rest and during adenosine stress can assess coronary vascular reactivity. We hypothesised that the non-contrast T1 response to vasodilator stress will be altered in patients with T2DM without CAD compared to controls due to coronary microvascular dysfunction. METHODS: Thirty-one patients with T2DM and sixteen matched healthy controls underwent CMR (3 T) for cine, rest and adenosine stress non-contrast T1-mapping (ShMOLLI), first-pass perfusion and late gadolinium enhancement (LGE) imaging...
October 25, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29061184/assessment-of-reverse-remodeling-predicted-by-myocardial-deformation-on-tissue-tracking-in-patients-with-severe-aortic-stenosis-a-cardiovascular-magnetic-resonance-imaging-study
#20
Ji-Won Hwang, Sung Mok Kim, Sung-Ji Park, Eun Jeong Cho, Eun Kyoung Kim, Sung-A Chang, Sang-Chol Lee, Yeon Hyeon Choe, Seung Woo Park
BACKGROUND: The technique of tissue tracking with balanced steady-state free precession cine sequences was introduced, and allowed myocardial strain to be derived directly, offering advantages over traditional myocardial tagging. The aim of this study was to evaluate the correlation between reverse remodeling as an outcome and left ventricular strain using cardiovascular magnetic resonance imaging (CMR) tissue tracking, and to evaluate prediction of reverse remodeling by myocardial deformation in patients with severe aortic stenosis (AS)...
October 23, 2017: Journal of Cardiovascular Magnetic Resonance
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