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Cardiovascular magnetic resonance CMR

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https://www.readbyqxmd.com/read/28317480/novel-insights-into-complex-cardiovascular-pathologies-using-4d-flow-analysis-by-cardiovascular-magnetic-resonance-imaging
#1
Adam James Lewandowski, Betty Raman, Rajarshi Banerjee, Matteo Milanesi
BACKGROUND: It is essential that we are able to assess variations in blood flow in order to fully understand cardiovascular function in disease pathologies and for identification of individuals at long-term risk of cardiovascular disease development. Qualitative and quantitative assessments of blood flow by imaging modalities have been limited, and much of the accurate quantification has relied on invasive measures. METHODS: This review discusses how four-dimensional velocity cardiovascular magnetic resonance (4D flow CMR) offers increasing potential for the non-invasive assessment of blood flow in the heart and major blood vessels such as the aorta...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28317398/cardiac-transplantation-towards-a-new-noninvasive-approach-of-cardiac-allograft-rejection
#2
Sophie I Mavrogeni, George Athanasopoulos, Aggeliki Gouziouta, Evangelos Leontiadis, Stamatis Adamopoulos, Genovefa Kolovou
Cardiac allograft rejection (CAR) may occur after transplantation and remains silent, until hemodynamic deterioration takes place. Endomyocardial biopsy (EMB) is applied to early detect CAR. Although, flexible bioptoms have decreased the incidence of lethal complications, EMB remains an invasive procedure carrying risk of tamponade and permanent heart block. Therefore, a new non-invasive approach is needed. Areas covered: AlloMap molecular expression testing and graft-derived cell-free DNA (GcfDNA) test can be used as blood indices of acute and chronic CAR, respectively...
March 20, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28315985/role-of-cardiovascular-magnetic-resonance-in-acute-and-chronic-ischemic-heart-disease
#3
A Baritussio, A Scatteia, C Bucciarelli-Ducci
Cardiovascular magnetic resonance (CMR) is a multi-parametric, multi-planar, non-invasive imaging technique, which allows accurate determination of biventricular function and precise myocardial tissue characterization in a one-stop-shop technique, free from the use of ionizing radiations. Though CMR has been increasingly applied over the last two decades in every-day clinical practice, its widest application has been in the assessment of ischemic cardiomyopathy.
March 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28302143/altered-aortic-3d-hemodynamics-and-geometry-in-pediatric-marfan-syndrome-patients
#4
Roel L F van der Palen, Alex J Barker, Emilie Bollache, Julio Garcia, Michael J Rose, Pim van Ooij, Luciana T Young, Arno A W Roest, Michael Markl, Joshua D Robinson, Cynthia K Rigsby
BACKGROUND: Blood flow dynamics make it possible to better understand the development of aortopathy and cardiovascular events in patients with Marfan syndrome (MFS). Aortic 3D blood flow characteristics were investigated in relation to aortic geometry in children and adolescents with MFS. METHODS: Twenty-five MFS patients (age 15.6 ± 4.0 years; 11 females) and 21 healthy controls (age 16.0 ± 2.6 years; 12 females) underwent magnetic resonance angiography and 4D flow CMR for assessment of thoracic aortic size and 3D blood flow velocities...
March 17, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28289525/cardiovascular-magnetic-resonance-imaging-assessment-of-outcomes-in-acute-myocardial-infarction
#5
REVIEW
Jamal N Khan, Gerry P McCann
Cardiovascular magnetic resonance (CMR) imaging uniquely characterizes myocardial and microvascular injury in acute myocardial infarction (AMI), providing powerful surrogate markers of outcomes. The last 10 years have seen an exponential increase in AMI studies utilizing CMR based endpoints. This article provides a contemporary, comprehensive review of the powerful role of CMR imaging in the assessment of outcomes in AMI. The theory, assessment techniques, chronology, importance in predicting left ventricular function and remodelling, and prognostic value of each CMR surrogate marker is described in detail...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28289524/assessment-of-stable-coronary-artery-disease-by-cardiovascular-magnetic-resonance-imaging-current-and-emerging-techniques
#6
REVIEW
James R J Foley, Sven Plein, John P Greenwood
Coronary artery disease (CAD) is a leading cause of death and disability worldwide. Cardiovascular magnetic resonance (CMR) is established in clinical practice guidelines with a growing evidence base supporting its use to aid the diagnosis and management of patients with suspected or established CAD. CMR is a multi-parametric imaging modality that yields high spatial resolution images that can be acquired in any plane for the assessment of global and regional cardiac function, myocardial perfusion and viability, tissue characterisation and coronary artery anatomy, all within a single study protocol and without exposure to ionising radiation...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28285594/defining-left-ventricular-remodeling-following-acute-st-segment-elevation-myocardial-infarction-using-cardiovascular-magnetic-resonance
#7
Heerajnarain Bulluck, Yun Yun Go, Gabriele Crimi, Andrew J Ludman, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Silvia Pica, Claudia Raineri, Alex Sirker, Anna S Herrey, Charlotte Manisty, Ashley Groves, James C Moon, Derek J Hausenloy
BACKGROUND: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. METHODS: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined...
March 13, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28284183/multiparametric-cardiac-magnetic-resonance-imaging-cmr-for-the-diagnosis-of-loeffler-s-endocarditis-a-case-report
#8
Mareike Gastl, Patrick Behm, Christoph Jacoby, Malte Kelm, Florian Bönner
BACKGROUND: Endocarditis parietalis fibroplastica Löfflein (EPF) is a rare form of primary restrictive cardiomyopathy with poor prognosis. It is generally caused by hypereosinophilic syndrome with eosinophilic penetration of the heart. This leads to congestive heart failure in three different stages. As a frequent manifestation of neoplastic diseases, cardiac involvement means poor prognosis. CASE PRESENTATION: The present report deals with a case of EPF caused by non-specified T-cell lymphoma (T-NOS)...
March 11, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28283244/left-atrial-mechanics-in-patients-with-acute-stemi-and-secondary-mitral-regurgitation-a-prospective-pilot-cmr-feature-tracking-study
#9
Tomas Lapinskas, Paulius Bučius, Laura Urbonaitė, Agnieta Stabinskaitė, Živilė Valuckienė, Lina Jankauskaitė, Rimantas Benetis, Remigijus Žaliūnas
BACKGROUND AND OBJECTIVE: Left atrium (LA) is an important biomarker of adverse cardiovascular outcomes and cerebrovascular events. This study aimed to evaluate LA myocardial deformation using cardiac magnetic resonance feature tracking (CMR-FT) in patients with acute ST-segment elevation myocardial infarction (STEMI) and secondary mitral regurgitation (MR). Additionally, to assess interobserver and intraobserver variability of the technique. MATERIALS AND METHODS: Twenty patients with STEMI underwent CMR with a 1...
March 1, 2017: Medicina
https://www.readbyqxmd.com/read/28279225/allogenic-adipose-derived-stem-cell-therapy-overcomes-ischemia-induced-microvessel-rarefaction-in-the-myocardium-systems-biology-study
#10
Gemma Vilahur, Blanca Oñate, Judit Cubedo, Maria Teresa Béjar, Gemma Arderiu, Esther Peña, Laura Casaní, Manuel Gutiérrez, Antoni Capdevila, Guillem Pons-Lladó, Francesc Carreras, Alberto Hidalgo, Lina Badimon
BACKGROUND: Myocardial microvascular loss after myocardial infarction (MI) remains a therapeutic challenge. Autologous stem cell therapy was considered as an alternative; however, it has shown modest benefits due to the impairing effects of cardiovascular risk factors on stem cells. Allogenic adipose-derived stem cells (ASCs) may overcome such limitations, and because of their low immunogenicity and paracrine potential may be good candidates for cell therapy. In the present study we investigated the effects of allogenic ASCs and their released products on cardiac rarefaction post MI...
March 9, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28275558/myocardial-strain-and-symptom-severity-in-severe-aortic-stenosis-insights-from-cardiovascular-magnetic-resonance
#11
Tarique Al Musa, Akhlaque Uddin, Peter P Swoboda, Pankaj Garg, Timothy A Fairbairn, Laura E Dobson, Christopher D Steadman, Anvesha Singh, Bara Erhayiem, Sven Plein, Gerald P McCann, John P Greenwood
BACKGROUND: Symptomatic severe aortic stenosis (AS) is a class I indication for replacement in patients when left ventricular ejection fraction (LVEF) is preserved. However, symptom reporting is often equivocal and decision making can be challenging. We aimed to quantify myocardial deformation using cardiovascular magnetic resonance (CMR) in patients classified by symptom severity. METHODS: Forty-two patients with severe AS referred to heart valve clinic were studied using tagged CMR imaging...
February 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28270219/quantification-of-aortic-stenosis-diagnostic-parameters-comparison-of-fast-3-direction-and-1-direction-phase-contrast-cmr-and-transthoracic-echocardiography
#12
Juliana Serafim da Silveira, Matthew Smyke, Adam V Rich, Yingmin Liu, Ning Jin, Debbie Scandling, Jennifer A Dickerson, Carlos E Rochitte, Subha V Raman, Lee C Potter, Rizwan Ahmad, Orlando P Simonetti
BACKGROUND: Aortic stenosis (AS) is a common valvular disorder, and disease severity is currently assessed by transthoracic echocardiography (TTE). However, TTE results can be inconsistent in some patients, thus other diagnostic modalities such as cardiovascular magnetic resonance (CMR) are demanded. While traditional unidirectional phase-contrast CMR (1Dir PC-CMR) underestimates velocity if the imaging plane is misaligned to the flow direction, multi-directional acquisitions are expected to improve velocity measurement accuracy...
March 7, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28270208/aortic-length-measurements-for-pulse-wave-velocity-calculation-manual-2d-vs-automated-3d-centreline-extraction
#13
Arna van Engelen, Miguel Silva Vieira, Isma Rafiq, Marina Cecelja, Torben Schneider, Hubrecht de Bliek, C Alberto Figueroa, Tarique Hussain, Rene M Botnar, Jordi Alastruey
BACKGROUND: Pulse wave velocity (PWV) is a biomarker for the intrinsic stiffness of the aortic wall, and has been shown to be predictive for cardiovascular events. It can be assessed using cardiovascular magnetic resonance (CMR) from the delay between phase-contrast flow waveforms at two or more locations in the aorta, and the distance on CMR images between those locations. This study aimed to investigate the impact of different distance measurement methods on PWV. We present and evaluate an algorithm for automated centreline tracking in 3D images, and compare PWV calculations using distances derived from 3D images to those obtained from a conventional 2D oblique-sagittal image of the aorta...
March 8, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28269194/atrioventricular-junction-avj-motion-tracking-a-software-tool-with-itk-vtk-qt
#14
Pengdong Xiao, Shuang Leng, Xiaodan Zhao, Hua Zou, Ru San Tan, Philip Wong, Liang Zhong
The quantitative measurement of the Atrioventricular Junction (AVJ) motion is an important index for ventricular functions of one cardiac cycle including systole and diastole. In this paper, a software tool that can conduct AVJ motion tracking from cardiovascular magnetic resonance (CMR) images is presented by using Insight Segmentation and Registration Toolkit (ITK), The Visualization Toolkit (VTK) and Qt. The software tool is written in C++ by using Visual Studio Community 2013 integrated development environment (IDE) containing both an editor and a Microsoft complier...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269193/dynamic-mapping-of-ventricular-function-from-cardiovascular-magnetic-resonance-imaging
#15
Maria Panayiotou, Peter Mountney, Alexander Brost, Daniel Toth, Tom Jackson, Jonathan M Behar, Christopher A Rinaldi, R James Housden, Kawal S Rhode
Heart failure is associated with substantial mortality and morbidity and remains the most common diagnosis in older patients. Based on experimental electrophysiologic studies, cardiac resynchronization therapy (CRT) for heart failure results in a maximum resynchronization effect when applied to the most delayed left ventricular (LV) site. Current clinical practice is to identify the optimal site using separate visualisation of scar and activation information. These must be mentally mapped into 3D, which is challenging and time-consuming for the electrophysiologist...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267539/assessment-of-left-ventricular-deformation-in-patients-with-ebstein-s-anomaly-by-cardiac-magnetic-resonance-tissue-tracking
#16
Xi Liu, Qin Zhang, Zhi-Gang Yang, Ke Shi, Hua-Yan Xu, Lin-Jun Xie, Li Jiang, Kai-Yue Diao, Ying-Kun Guo
PURPOSE: The aim of this study was to clarify the feasibility of myocardial strain using cardiovascular magnetic resonance (CMR) for the evaluation of left ventricular (LV) deformation in patients with Ebstein's anomaly (EA). MATERIALS AND METHODS: We recruited 32 patients with EA and 30 controls for CMR examination and measured LV function, dimension and tissue tracking parameters (the global and regional radial, circumferential and longitudinal peak strain), together with the right ventricle (RV) dimension...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28263147/the-improvement-of-torsion-assessed-by-cardiovascular-magnetic-resonance-feature-tracking-after-coronary-artery-bypass-grafting-a-sensitive-index-of-cardiac-function
#17
Nan Cheng, Liuquan Cheng, Rong Wang, Lin Zhang, Changqing Gao
OBJECTIVE: The aim of this study was to quantify left ventricular torsion by newly applied cardiovascular magnetic resonance feature tracking (CMR-FT), and to evaluate the clinical value of the ventricular torsion as a sensitive indicator of cardiac function by comparison of preoperative and postoperative torsion. METHODS: A total of 54 volunteers and 36 patients with previous myocardial infarction (MI) and LV ejection fraction (EF) between 30%-50% were screened preoperatively or postoperatively by MRI...
February 28, 2017: Heart Surgery Forum
https://www.readbyqxmd.com/read/28260526/comparison-of-ct-and-cmr-for-detection-and-quantification-of-carotid-artery-calcification-the-rotterdam-study
#18
Blerim Mujaj, Andrés M Arias Lorza, Arna van Engelen, Marleen de Bruijne, Oscar H Franco, Aad van der Lugt, Meike W Vernooij, Daniel Bos
BACKGROUND: Carotid artery atherosclerosis is an important risk factor for stroke. As such, quantitative imaging of carotid artery calcification, as a proxy of atherosclerosis, has become a cornerstone of current stroke research. Yet, population-based data comparing the computed tomography (CT) and cardiovascular magnetic resonance (CMR) for the detection and quantification of calcification remain scarce. METHODS: A total of 684 participants from the population-based Rotterdam Study underwent both a CT and CMR of the carotid artery bifurcation to quantify the amount of carotid artery calcification (mean interscan interval: 4...
March 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28256176/stress-cardiovascular-magnetic-resonance-imaging-current-and-future-perspectives
#19
REVIEW
Thu-Thao Le, Weiting Huang, Jennifer Ann Bryant, Stuart Alexander Cook, Calvin Woon-Loong Chin
Vasodilator and dobutamine are the main pharmacological agents used in current stress cardiovascular magnetic resonance (CMR). Exercise stress has well-established advantages and it is commonly used in other stress imaging, but the technical considerations have limited its use in stress CMR. In this review, we will describe the diagnostic performance, prognostic value, strengths and challenges of current stress CMR techniques. We will also discuss future perspectives of exercise stress CMR. Areas covered: Despite notable mechanistic differences, vasodilator and dobutamine stress CMR offer similar diagnostic and prognostic value in coronary artery disease...
March 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28248005/evaluation-of-the-ecg-based-selvester-scoring-method-to-estimate-myocardial-scar-burden-and-predict-clinical-outcome-in-patients-with-left-bundle-branch-block-with-comparison-to-late-gadolinium-enhancement-cmr-imaging
#20
Uzma Chaudhry, Pyotr G Platonov, Robert Jablonowski, Jean-Philippe Couderc, Henrik Engblom, Xiajuang Xia, Björn Wieslander, Brett D Atwater, David G Strauss, Jesper Van der Pals, Martin Ugander, Marcus Carlsson, Rasmus Borgquist
BACKGROUND: Myocardial scar burden quantification is an emerging clinical parameter for risk stratification of sudden cardiac death and prediction of ventricular arrhythmias in patients with left ventricular dysfunction. We investigated the relationships among semiautomated Selvester score burden and late gadolinium enhancement-cardiovascular magnetic resonance (LGE-CMR) assessed scar burden and clinical outcome in patients with underlying heart failure, left bundle branch block (LBBB) and implantable cardioverter-defibrillator (ICD) treatment...
March 1, 2017: Annals of Noninvasive Electrocardiology
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