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Cardiovascular magnetic resonance CMR

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https://www.readbyqxmd.com/read/28424090/targeted-endomyocardial-biopsy-guided-by-real-time-cardiovascular-magnetic-resonance
#1
Christina Unterberg-Buchwald, Christian Oliver Ritter, Verena Reupke, Robin Niklas Wilke, Christine Stadelmann, Michael Steinmetz, Andreas Schuster, Gerd Hasenfuß, Joachim Lotz, Martin Uecker
BACKGROUND: Endomyocardial biopsies (EMB) are an important diagnostic tool for myocarditis and other infiltrative cardiac diseases. Routinely, biopsies are obtained under fluoroscopic guidance with a substantial radiation burden. Despite procedural success, there is a large sampling error caused by missing the affected myocardium. Therefore, multiple (>6) biopsies are taken in the clinical setting. In cardiovascular magnetic resonance (CMR), late gadolinium enhancement (LGE) depicts areas of affected myocardium in myocarditis or in other infiltrative cardiomyopathies...
April 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28421174/utility-of-cardiovascular-magnetic-resonance-derived-wave-intensity-analysis-as-a-marker-of-ventricular-function-in-children-with-heart-failure-and-normal-ejection-fraction
#2
Hopewell N Ntsinjana, Robin Chung, Paolo Ciliberti, Vivek Muthurangu, Silvia Schievano, Jan Marek, Kim H Parker, Andrew M Taylor, Giovanni Biglino
OBJECTIVE: This study sought to explore the diagnostic insight of cardiovascular magnetic resonance (CMR)-derived wave intensity analysis to better study systolic dysfunction in young patients with chronic diastolic dysfunction and preserved ejection fraction (EF), comparing it against other echocardiographic and CMR parameters. BACKGROUND: Evaluating systolic and diastolic dysfunctions in children is challenging, and a gold standard method is currently lacking...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28416981/relationship-between-right-and-left-ventricular-function-in-candidates-for-implantable-cardioverter-defibrillator-with-low-left-ventricular-ejection-fraction
#3
Laura Jimenez-Juan, Gauri R Karur, Kim A Connelly, Djeven Deva, Raymond T Yan, Rachel M Wald, Sheldon Singh, General Leung, Anastasia Oikonomou, Paul Dorian, Paul Angaran, Andrew T Yan
BACKGROUND: Indications for the primary prevention of sudden death using an implantable cardioverter defibrillator (ICD) are based predominantly on left ventricular ejection fraction (LVEF). However, right ventricular ejection fraction (RVEF) is also a known prognostic factor in a variety of structural heart diseases that predispose to sudden cardiac death. We sought to investigate the relationship between right and left ventricular parameters (function and volume) measured by cardiovascular magnetic resonance (CMR) among a broad spectrum of patients considered for an ICD...
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28400924/risk-of-ventricular-arrhythmia-in-patients-with-myocardial-infarction-and-non-obstructive-coronary-arteries-and-normal-ejection-fraction
#4
Loïc Bière, Marjorie Niro, Hervé Pouliquen, Jean-Baptiste Gourraud, Fabrice Prunier, Alain Furber, Vincent Probst
AIM: To assess the arrhythmic determinants and prognosis of patients presenting with myocardial infarction and non-obstructive coronary arteries (MINOCA) with normal ejection fraction (EF). METHODS: This is an observational analysis of 131 MINOCA patients with normal EF. Three cardiac magnetic resonance (CMR) diagnosis classes were recognized according to the late gadolinium enhancement (LGE) pattern: Myocardial infarction (MI) (n = 34), myocarditis (n = 47), and "no LGE" (n = 50)...
March 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28395671/longitudinal-assessment-of-right-ventricular-structure-and-function-by-cardiovascular-magnetic-resonance-in-breast-cancer-patients-treated-with-trastuzumab-a-prospective-observational-study
#5
Ashita Barthur, Christine Brezden-Masley, Kim A Connelly, Vinita Dhir, Kelvin K W Chan, Rashida Haq, Anish Kirpalani, Joseph J Barfett, Laura Jimenez-Juan, Gauri R Karur, Djeven P Deva, Andrew T Yan
BACKGROUND: There are limited data on the effects of trastuzumab on the right ventricle (RV). Therefore, we sought to evaluate the temporal changes in right ventricular (RV) structure and function as measured by cardiovascular magnetic resonance (CMR), and their relationship with left ventricular (LV) structure and function in breast cancer patients treated with trastuzumab. METHODS: Prospective, longitudinal, observational study involving 41 women with HER2+ breast cancer who underwent serial CMR at baseline, 6, 12, and 18 months after initiation of trastuzumab...
April 10, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28390413/does-stress-perfusion-imaging-improve-the-diagnostic-accuracy-of-late-gadolinium-enhanced-cardiac-magnetic-resonance-for-establishing-the-etiology-of-heart-failure
#6
Gaurav S Gulsin, Abishek Shetye, Jeffrey Khoo, Daniel J Swarbrick, Eylem Levelt, Florence Y Lai, Iain B Squire, Jayanth R Arnold, Gerry P McCann
BACKGROUND: Late gadolinium enhanced cardiovascular magnetic resonance (LGE-CMR) has excellent specificity, sensitivity and diagnostic accuracy for differentiating between ischemic cardiomyopathy (ICM) and non-ischemic dilated cardiomyopathy (NICM). CMR first-pass myocardial perfusion imaging (perfusion-CMR) may also play role in distinguishing heart failure of ischemic and non-ischemic origins, although the utility of additional of stress perfusion imaging in such patients is unclear...
April 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28389968/predictors-of-left-ventricular-remodeling-after-st-elevation-myocardial-infarction
#7
Tom Hendriks, Minke H T Hartman, Pieter J J Vlaar, Niek H J Prakken, Yldau M Y van der Ende, Chris P H Lexis, Dirk J van Veldhuisen, Iwan C C van der Horst, Erik Lipsic, Robin Nijveldt, Pim van der Harst
Adverse left ventricular (LV) remodeling after acute ST-elevation myocardial infarction (STEMI) is associated with morbidity and mortality. We studied clinical, biochemical and angiographic determinants of LV end diastolic volume index (LVEDVi), end systolic volume index (LVESVi) and mass index (LVMi) as global LV remodeling parameters 4 months after STEMI, as well as end diastolic wall thickness (EDWT) and end systolic wall thickness (ESWT) of the non-infarcted myocardium, as compensatory remote LV remodeling parameters...
April 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28387860/prolonged-central-circulation-transit-time-in-patients-with-hfpef-and-hfref-by-magnetic-resonance-imaging
#8
Jie J Cao, Laura Li, Jeannette McLaughlin, Michael Passick
Aims: Prolonged central circulation transit time (TT) has long been associated with heart failure (HF) and left ventricular (LV) dysfunction. In this study, we assessed the central circulation TT using cardiovascular magnetic resonance imaging (CMR) in patients with HF of preserved ejection fraction (HFpEF) and of reduced EF (HFrEF) and investigated its relation to haemodynamics. Methods and results: Fifty eight prospectively recruited volunteers underwent CMR. TT was taken as the time between the peaks of time-intensity curves from first pass perfusion images and normalized to cardiac cycle length intervals...
April 6, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28379356/decreased-glycolytic-metabolism-in-non-compaction-cardiomyopathy-by-18f-fluoro-2-deoxyglucose-positron-emission-tomography-new-insights-into-pathophysiological-mechanisms-and-clinical-implications
#9
Marcelo Dantas Tavares de Melo, Maria Clementina Pinto Giorgi, Antonildes Nascimento Assuncao, Roberto Nery Dantas, Jose de Arimateia Araujo Filho, Jose Rodrigues Parga Filho, Ana Luiza de Souza Bierrenbach, Camila Rocon de Lima, José Soares, José Claudio Meneguetti, Charles Mady, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Edimar Alcides Bocchi, Vera Maria Cury Salemi
Aims: The pathophysiological mechanisms of left ventricular non-compaction cardiomyopathy (LVNC) remain controversial. This study performed combined 18F-fluoro-2-deoxyglucose dynamic positron emission tomography (FDG-PET) and 99mTc-sestamibi single-photon emission computed tomography (SPECT) studies to evaluate myocardial glucose metabolism and perfusion in patients with LVNC and their clinical implications. Methods and results: Thirty patients (41 ± 12 years, 53% male) with LVNC, diagnosed by cardiovascular magnetic resonance (CMR) criteria, and eight age-matched healthy controls (42 ± 12 years, 50% male) were prospectively recruited to undergo FDG-PET with measurement of the myocardial glucose uptake rate (MGU) and SPECT to investigate perfusion-metabolism patterns...
March 30, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28376820/blood-correction-reduces-variability-and-gender-differences-in-native-myocardial-t1-values-at-1-5%C3%A2-t-cardiovascular-magnetic-resonance-a-derivation-validation-approach
#10
Jannike Nickander, Magnus Lundin, Goran Abdula, Peder Sörensson, Stefania Rosmini, James C Moon, Peter Kellman, Andreas Sigfridsson, Martin Ugander
BACKGROUND: Myocardial native T1 measurements are likely influenced by intramyocardial blood. Since blood T1 is both variable and longer compared to myocardial T1, this will degrade the precision of myocardial T1 measurements. Precision could be improved by correction, but the amount of correction and the optimal blood T1 variables to correct with are unknown. We hypothesized that an appropriate correction would reduce the standard deviation (SD) of native myocardial T1. METHODS: Consecutive patients (n = 400) referred for CMR with known or suspected heart disease were split into a derivation cohort for model construction (n = 200, age 51 ± 18 years, 50% male) and a validation cohort for assessing model performance (n = 200, age 48 ± 17 years, 50% male)...
April 5, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28373784/left-ventricular-noncompaction-a-rare-form-of-cardiomyopathy-revelation-modes-and-predictors-of-mortality-in-adults-through-23-cases
#11
Iliyasse Asfalou, Sanae Boulaamayl, Maha Raissouni, Najat Mouine, Mohamed Sabry, Jamal Kheyi, Nawal Doghmi, Aatif Benyass
OBJECTIVES: To describe modes of clinical presentation and echocardiographic, angiographic, and rhythmic features, and prognostic characteristics of left ventricular noncompaction cardiomyopathy (LVNC) in North African adults, through one of the first series in Morocco. BACKGROUND: LVNC is a rare congenital disorder, described for the first time by Engberding in 1984. The suspected diagnosis in thromboembolic, hemodynamic, or rhythm events requires both echocardiography and cardiovascular magnetic resonance (CMR)...
April 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28373095/out-of-hospital-cardiac-arrest-survivors-with-inconclusive-coronary-angiogram-impact-of-cardiovascular-magnetic-resonance-on-clinical-management-and-decision-making
#12
A Baritussio, A Zorzi, A Ghosh Dastidar, A Susana, G Mattesi, J C L Rodrigues, G Biglino, A Scatteia, E De Garate, J Strange, L Cacciavillani, S Iliceto, A Nisbet, G D Angelini, D Corrado, M Perazzolo Marra, C Bucciarelli-Ducci
BACKGROUND: Non-traumatic out of hospital cardiac arrest (OHCA) is the leading cause of death worldwide, mainly due to acute coronary syndromes. Urgent coronary angiography with view to revascularisation is recommended in patients with suspected acute coronary syndrome. Diagnosis and management of patients with inconclusive coronary angiogram (unobstructed coronaries or unidentified culprit lesion) is challenging. We sought to assess the role of Cardiovascular Magnetic Resonance (CMR) in the diagnosis and management of OHCA survivors with an inconclusive coronary angiogram...
March 31, 2017: Resuscitation
https://www.readbyqxmd.com/read/28369259/diagnostic-value-of-global-myocardial-perfusion-reserve-assessment-based-on-coronary-sinus-flow-measurements-using-cardiovascular-magnetic-resonance-in-addition-to-myocardial-stress-perfusion-imaging
#13
Zornitsa Shomanova, Anca Florian, Michael Bietenbeck, Johannes Waltenberger, Udo Sechtem, Ali Yilmaz
Aims: Myocardial perfusion reserve (MPR) is defined as the maximal possible increase in myocardial blood flow (MBF) above baseline conditions. Global MBF can be measured non-invasively by means of coronary sinus flow velocity encoded cine (VENC) cardiovascular magnetic resonance (CMR). We aimed to explore the relationship between global MBF/MPR and the extent and severity of coronary artery disease (CAD) in patients referred for CAD work-up by adenosine-stress CMR. Methods and results: Fifty-eight patients with suspected obstructive CAD underwent both adenosine-stress CMR and invasive coronary angiography...
March 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28369148/right-atrial-volume-by-cardiovascular-magnetic-resonance-predicts-mortality-in-patients-with-heart-failure-with-reduced-ejection-fraction
#14
Alexander Ivanov, Ambreen Mohamed, Ahmed Asfour, Jean Ho, Saadat A Khan, Onn Chen, Igor Klem, Kumudha Ramasubbu, Sorin J Brener, John F Heitner
BACKGROUND: Right Atrial Volume Index (RAVI) measured by echocardiography is an independent predictor of morbidity in patients with heart failure (HF) with reduced ejection fraction (HFrEF). The aim of this study is to evaluate the predictive value of RAVI assessed by cardiac magnetic resonance (CMR) for all-cause mortality in patients with HFrEF and to assess its additive contribution to the validated Meta-Analysis Global Group in Chronic heart failure (MAGGIC) score. METHODS AND RESULTS: We identified 243 patients (mean age 60 ± 15; 33% women) with left ventricular ejection fraction (LVEF) ≤ 35% measured by CMR...
2017: PloS One
https://www.readbyqxmd.com/read/28363200/evolution-of-right-ventricular-size-over-time-after-tetralogy-of-fallot-repair-a-longitudinal-cardiac-magnetic-resonance-study
#15
Tobias Rutz, Fransis Ghandour, Christian Meierhofer, Susanne Naumann, Stefan Martinoff, Rüdiger Lange, Peter Ewert, Heiko C Stern, Sohrab Fratz
Aims: It is commonly believed that pulmonary regurgitation (PR) after surgical repair of tetralogy of Fallot (TOF) leads to progressive right ventricular (RV) enlargement. However, progressive RV dilatation has never clearly been documented in this patient population. Therefore, we studied the size of the RV over time in patients after surgical TOF repair. Methods and results: Fifty-one consecutive patients after surgical TOF repair underwent at least two cardiovascular magnetic resonance (CMR) exams using a single CMR scanner...
March 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28359292/cardiac-4d-phase-contrast-cmr-at-9-4%C3%A2-t-using-self-gated-ultra-short-echo-time-ute-imaging
#16
M Krämer, A G Motaal, K-H Herrmann, B Löffler, J R Reichenbach, G J Strijkers, V Hoerr
BACKGROUND: Time resolved 4D phase contrast (PC) cardiovascular magnetic resonance (CMR) in mice is challenging due to long scan times, small animal ECG-gating and the rapid blood flow and cardiac motion of small rodents. To overcome several of these technical challenges we implemented a retrospectively self-gated 4D PC radial ultra-short echo-time (UTE) acquisition scheme and assessed its performance in healthy mice by comparing the results with those obtained with an ECG-triggered 4D PC fast low angle shot (FLASH) sequence...
March 31, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28353309/cardiac-magnetic-resonance-imaging-derived-quantification-of-myocardial-ischemia-and-scar-improves-risk-stratification-and-patient-management-in-stable-coronary-artery-disease
#17
Dominik Buckert, Maciej Cieslik, Raid Tibi, Michael Radermacher, Wolfgang Rottbauer, Peter Bernhardt
BACKGROUND: Quantification of myocardial ischemia and necrosis might ameliorate prognostic models and lead to improved patient management. However, no standardized consensus on how to assess and quantify these parameters has been established. The aim of this study was to quantify these variables by cardiac magnetic resonance imaging (CMR) and to establish possible incremental implications in cardiovascular risk prediction. METHODS: This study is a retrospective analysis of patients with known or suspected coronary artery disease (CAD) referred for adenosine perfusion CMR was performed...
March 29, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28351901/association-between-mid-wall-late-gadolinium-enhancement-and-sudden-cardiac-death-in-patients-with-dilated-cardiomyopathy-and-mild-and-moderate-left-ventricular-systolic-dysfunction
#18
Brian Halliday, Ankur Gulati, Aamir Ali, Kaushik Guha, Simon J Newsome, Monika Arzanauskaite, Vassilios S Vassiliou, Amrit S Lota, Cemil Izgi, Upasana Tayal, Zohya Khalique, Colin Stirrat, Dominique Auger, Nilesh Pareek, Tevfik F Ismail, Stuart D Rosen, Ali Vazir, Francisco Alpendurada, John Gregson, Michael P Frenneaux, Martin R Cowie, John G F Cleland, Stuart A Cook, Dudley J Pennell, Sanjay K Prasad
Background -Current guidelines only recommend the use of an implantable cardioverter defibrillator (ICD) in patients with dilated cardiomyopathy (DCM) for the primary prevention of sudden cardiac death (SCD) in those with a left ventricular ejection fraction (LVEF)<35%. However, registries of out-of-hospital cardiac arrests demonstrate that 70-80% of such patients have a LVEF>35%. Patients with a LVEF>35% also have low competing risks of death from non-sudden causes. Therefore, those at high-risk of SCD may gain longevity from successful ICD therapy...
March 28, 2017: Circulation
https://www.readbyqxmd.com/read/28351402/abnormal-t2-mapping-cardiovascular-magnetic-resonance-correlates-with-adverse-clinical-outcome-in-patients-with-suspected-acute-myocarditis
#19
Maximilian Spieker, Sebastian Haberkorn, Mareike Gastl, Patrick Behm, Stratis Katsianos, Patrick Horn, Christoph Jacoby, Bernhard Schnackenburg, Petra Reinecke, Malte Kelm, Ralf Westenfeld, Florian Bönner
BACKGROUND: While most patients recover from suspected acute myocarditis (sAMC) some develop progressive disease with 5-year mortality up to 20%. Recently, parametric Cardiovascular Magnetic Resonance (CMR) approaches, quantifying native T1 and T2 relaxation time, have demonstrated the ability to increase diagnostic accuracy. However, prognostic implications of T2 values in this cohort are unknown. The purpose of the study was to investigate the prognostic relevance of elevated CMR T2 values in patients with sAMC...
March 29, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28343948/left-ventricular-non-compaction-a-cardiomyopathy-with-acceptable-prognosis-in-children
#20
Tao Tian, Yankun Yang, Lanlan Zhou, Fang Luo, Yuehua Li, Peng Fan, Xueqi Dong, Yaxin Liu, Jingang Cui, Xianliang Zhou
BACKGROUND: Data on children with left ventricular non-compaction (LVNC) is sparse. The purpose of this study was to evaluate its clinical profiles in a population of Chinese children. METHODS: From January 2010 to March 2016, consecutive Chinese children (aged <18 years) with LVNC diagnosed by cardiovascular magnetic resonance (CMR) were prospectively recruited at Fuwai Hospital. RESULTS: A total of 41 Chinese children (male: 28%; mean age: 14±4years) were included in this study...
March 1, 2017: Heart, Lung & Circulation
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