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Cardiovascular magnetic resonance CMR

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https://www.readbyqxmd.com/read/28103933/quantification-of-myocardial-deformation-in-children-by-cardiovascular-magnetic-resonance-feature-tracking-determination-of-reference-values-for-left-ventricular-strain-and-strain-rate
#1
Florian André, Daniëlle Robbers-Visser, Astrid Helling-Bakki, Angela Föll, Andreas Voss, Hugo A Katus, Willem A Helbing, Sebastian J Buss, Joachim G Eichhorn
BACKGROUND: The objective assessment of global and regional cardiac function in children has shown to be clinically relevant but is challenging to conduct. Cardiovascular magnetic resonance (CMR) has emerged as a valuable diagnostic modality especially in patients with cardiomyopathy or congenital heart disease. However, data on the normal cardiac deformation in children assessed by CMR is lacking at present. Thus, the aim of this study was to provide reference values for cardiac strain and strain rate in children and adolescents derived from CMR feature tracking (FT) measurements...
December 5, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28096723/myocardial-t1-and-t2-mapping-techniques-and-clinical-applications
#2
REVIEW
Pan Ki Kim, Yoo Jin Hong, Dong Jin Im, Young Joo Suh, Chul Hwan Park, Jin Young Kim, Suyon Chang, Hye-Jeong Lee, Jin Hur, Young Jin Kim, Byoung Wook Choi
Cardiac magnetic resonance (CMR) imaging is widely used in various medical fields related to cardiovascular diseases. Rapid technological innovations in magnetic resonance imaging in recent times have resulted in the development of new techniques for CMR imaging. T1 and T2 image mapping sequences enable the direct quantification of T1, T2, and extracellular volume fraction (ECV) values of the myocardium, leading to the progressive integration of these sequences into routine CMR settings. Currently, T1, T2, and ECV values are being recognized as not only robust biomarkers for diagnosis of cardiomyopathies, but also predictive factors for treatment monitoring and prognosis...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28095878/black-blood-thrombus-imaging-bti-a-contrast-free-cardiovascular-magnetic-resonance-approach-for-the-diagnosis-of-non-acute-deep-vein-thrombosis
#3
Guoxi Xie, Hanwei Chen, Xueping He, Jianke Liang, Wei Deng, Zhuonan He, Yufeng Ye, Qi Yang, Xiaoming Bi, Xin Liu, Debiao Li, Zhaoyang Fan
BACKGROUND: Deep vein thrombosis (DVT) is a common but elusive illness that can result in long-term disability or death. Accurate detection of thrombosis and assessment of its size and distribution are critical for treatment decision-making. In the present study, we sought to develop and evaluate a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and variable flip angle turbo-spin-echo readout, for the diagnosis of non-acute DVT...
January 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28090249/multimodality-imaging-for-left-ventricular-hypertrophy-severity-grading-a-methodological-review
#4
REVIEW
Maaike Alkema, Ernest Spitzer, Osama I I Soliman, Christian Loewe
Left ventricular hypertrophy (LVH), defined by an increase in left ventricular mass (LVM), is a common cardiac finding generally caused by an increase in pressure or volume load. Assessing severity of LVH is of great clinical value in terms of prognosis and treatment choices, as LVH severity grades correlate with the risk for presenting cardiovascular events. The three main cardiac parameters for the assessment of LVH are wall thickness, LVM, and LV geometry. Echocardiography, with large availability and low cost, is the technique of choice for their assessment...
December 2016: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28087602/novel-application-of-3d-contrast-enhanced-cmr-to-define-fibrotic-structure-of-the-human-sinoatrial-node-in-vivo
#5
Thomas A Csepe, Jichao Zhao, Lidiya V Sul, Yufeng Wang, Brian J Hansen, Ning Li, Anthony J Ignozzi, Anna Bratasz, Kimerly A Powell, Ahmet Kilic, Peter J Mohler, Paul M L Janssen, John D Hummel, Orlando P Simonetti, Vadim V Fedorov
AIMS: The adult human sinoatrial node (SAN) has a specialized fibrotic intramural structure (35-55% fibrotic tissue) that provides mechanical and electrical protection from the surrounding atria. We hypothesize that late gadolinium-enhanced cardiovascular magnetic resonance (LGE-CMR) can be applied to define the fibrotic human SAN structure in vivo. METHODS AND RESULTS: LGE-CMR atrial scans of healthy volunteers (n olu, 23-52 y.o.) using a 3 Tesla magnetic resonance imaging system with a spatial resolution of 1...
January 13, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28077133/t1-and-t2-mapping-for-evaluation-of-myocardial-involvement-in-patients-with-anca-associated-vasculitides
#6
Simon Greulich, Agnes Mayr, Daniel Kitterer, Joerg Latus, Joerg Henes, Hannah Steubing, Philipp Kaesemann, Alexandru Patrascu, Andreas Greiser, Stefan Groeninger, Niko Braun, M Dominik Alscher, Udo Sechtem, Heiko Mahrholdt
BACKGROUND: Myocardial involvement in AAV patients might be silent, presenting with no or nonspecific symptoms, normal ECG, and preserved left-ventricular ejection fraction (LV-EF). Since up to 50% of deaths in these patients may be due to myocardial involvement, a reliable diagnostic tool is warranted. In contrast to LGE-CMR, which has its strengths in detecting focal inflammatory or fibrotic processes, recent mapping techniques are able to detect even subtle, diffuse inflammatory or fibrotic processes...
January 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28065166/the-predictive-capabilities-of-a-novel-cardiovascular-magnetic-resonance-derived-marker-of-cardiopulmonary-reserve-on-established-prognostic-surrogate-markers-in-patients-with-pulmonary-vascular-disease-results-of-a-longitudinal-pilot-study
#7
Timothy J Baillie, Samuel Sidharta, Peter M Steele, Stephen G Worthley, Scott Willoughby, Karen Teo, Prashanthan Sanders, Stephen J Nicholls, Matthew I Worthley
BACKGROUND: No unified method exists to effectively predict and monitor progression of pulmonary arterial hypertension (PAH). We assessed the longitudinal relationship between a novel marker of cardiopulmonary reserve and established prognostic surrogate markers in patients with pulmonary vascular disease. METHODS AND RESULTS: Twenty participants with confirmed (n = 14) or at high risk (n = 6) for PAH underwent cardiovascular magnetic resonance (CMR) at baseline and after ~6 months of guideline-appropriate management...
January 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28063459/cardiac-remodeling-following-reperfused-acute-myocardial-infarction-is-linked-to-the-concomitant-evolution-of-vascular-function-as-assessed-by-cardiovascular-magnetic-resonance
#8
Olivier Huttin, Damien Mandry, Romain Eschalier, Lin Zhang, Emilien Micard, Freddy Odille, Marine Beaumont, Renaud Fay, Jacques Felblinger, Edoardo Camenzind, Faïez Zannad, Nicolas Girerd, Pierre Y Marie
BACKGROUND: Left ventricular (LV) remodeling following acute myocardial infarction (MI) is difficult to predict at an individual level although a possible interfering role of vascular function has yet to be considered to date. This study aimed to determine the extent to which this LV remodeling is influenced by the concomitant evolution of vascular function and LV loading conditions, as assessed by phase-contrast Cardiovascular Magnetic Resonance (CMR) of the ascending aorta. METHODS: CMR was performed in 121 patients, 2-4 days after reperfusion of a first ST-segment elevation myocardial infarction and 6 months thereafter...
January 4, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28061823/a-case-report-in-cardiovascular-magnetic-resonance-the-contrast-agent-matters-in-amyloid
#9
Marianna Fontana, Thomas A Treibel, Ana Martinez-Naharro, Stefania Rosmini, Raymond Y Kwong, Julian D Gillmore, Philip N Hawkins, James C Moon
BACKGROUND: Cardiac amyloidosis is a progressive but underdiagnosed and underappreciated cause of heart failure. In the last few years, cardiovascular magnetic resonance (CMR) has become the gold standard for non invasive diagnosis of cardiac amyloidosis with the characteristic subendocardial late gadolinium enhancement. CASE PRESENTATION: We describe a case of a patient who, in the process of aligning protocols for a trial between different centers, had a paired study with two different contrast agents, Dotarem® and MultiHance®...
January 7, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28056808/comparison-of-global-myocardial-strain-assessed-by-cardiovascular-magnetic-resonance-tagging-and-feature-tracking-to-infarct-size-at-predicting-remodelling-following-stemi
#10
Abhishek M Shetye, Sheraz A Nazir, Naveed A Razvi, Nathan Price, Jamal N Khan, Florence Y Lai, Iain B Squire, Gerald P McCann, Jayanth R Arnold
BACKGROUND: To determine if global strain parameters measured by cardiovascular magnetic resonance (CMR) acutely following ST-segment Elevation Myocardial Infarction (STEMI) predict adverse left ventricular (LV) remodelling independent of infarct size (IS). METHODS: Sixty-five patients with acute STEMI (mean age 60 ± 11 years) underwent CMR at 1-3 days post-reperfusion (baseline) and at 4 months. Global peak systolic circumferential strain (GCS), measured by tagging and Feature Tracking (FT), and global peak systolic longitudinal strain (GLS), measured by FT, were calculated at baseline, along with IS...
January 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28040191/left-ventricular-function-in-children-and-adolescents-with-arrhythmogenic-right-ventricular-cardiomyopathy
#11
Paweena Chungsomprasong, Robert Hamilton, Wietske Luining, Meena Fatah, Shi-Joon Yoo, Lars Grosse-Wortmann
The aim of this study was to determine if left ventricular (LV) contractility is reduced in children with arrhythmogenic right ventricular cardiomyopathy (ARVC). For this retrospective study, children and adolescents undergoing a workup for ARVC were characterized according to the revised Task Force Criteria (rTFC). LV strain, rotation, and torsion were measured by feature-tracking cardiovascular magnetic resonance imaging (CMR). Of 142 pediatric patients, 41% had no, 23% possible, 20% borderline, and 16% definite ARVC...
December 2, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28038815/circadian-variation-in-acute-myocardial-infarct-size-assessed-by-cardiovascular-magnetic-resonance-in-reperfused-stemi-patients
#12
Heerajnarain Bulluck, Jennifer Nicholas, Gabriele Crimi, Steven K White, Andrew J Ludman, Silvia Pica, Claudia Raineri, Hector A Cabrera-Fuentes, Derek Yellon, Jose Rodriguez-Palomares, David Garcia-Dorado, Derek J Hausenloy
OBJECTIVE: Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. We aimed to investigate this phenomenon using acute MI size measured by cardiovascular magnetic resonance (CMR). METHODS: Patient-level data was obtained from 4 randomized controlled trials investigating the MI-limiting effects of cardioprotective therapies in this pooled analysis...
December 19, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28029315/left-ventricular-dysfunction-with-trastuzumab-therapy-is-primary-prevention-the-best-option
#13
Paaladinesh Thavendiranathan, Eitan Amir
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
December 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28027767/t1-mapping-cardiovascular-magnetic-resonance-imaging-to-detect-myocarditis-impact-of-slice-orientation-on-the-diagnostic-performance
#14
Sebastian Bohnen, Ulf K Radunski, Gunnar K Lund, Enver Tahir, Maxim Avanesov, Christian Stehning, Bernhard Schnackenburg, Gerhard Adam, Stefan Blankenberg, Kai Muellerleile
BACKGROUND: T1 mapping is a promising diagnostic tool to improve the diagnostic accuracy of cardiovascular magnetic resonance (CMR) in patients with suspected myocarditis. However, there are currently no data on the potential influence of slice orientation on the diagnostic performance of CMR. Thus, we compared the diagnostic performance of global myocardial T1 and extracellular volume (ECV) values to differentiate patients with myocarditis from healthy individuals between different slice orientations...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28027750/multi-parametric-quantification-of-tricuspid-regurgitation-using-cardiovascular-magnetic-resonance-a-comparison-to-echocardiography
#15
Diego Medvedofsky, Javier Leon Jimenez, Karima Addetia, Amita Singh, Roberto M Lang, Victor Mor-Avi, Amit R Patel
BACKGROUND: Velocity-encoding is used to quantify tricuspid regurgitation (TR) by cardiovascular magnetic resonance (CMR), but requires additional dedicated imaging. We hypothesized that size and signal intensity (SI) of the cross-sectional TR jet area in the right atrium in short-axis steady-state free-precession images could be used to assess TR severity. METHODS: We studied 61 patients with TR, who underwent CMR and echocardiography within 24h. TR severity was determined by vena contracta: severe (N=20), moderate or mild (N=41)...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28027743/igg4-related-cardiovascular-disease-the-emerging-role-of-cardiovascular-imaging
#16
REVIEW
Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou
Immunoglobulin 4-related disease (IgG4-related disease) is a systemic inflammatory disease that presents with increases of serum IgG4. It may affect various systems, including the cardiovascular (CV) system. Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis. IgG4-related disease is characterized by fibrosclerosis, lymphocytic infiltration and presence of IgG4-positive plasma cells. The disease usually responds to treatment with corticosteroids and/or immunosuppressive medication...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28011840/cardiac-mri-anatomy-and-function-as-a-substrate-for-arrhythmias
#17
Chiara Bucciarelli-Ducci, Anna Baritussi, Angelo Auricchio
The use of cardiovascular magnetic resonance (CMR) has been implemented in the diagnostic work-up of patients with cardiomyopathies by providing an accurate assessment of biventricular volumes and function and a detailed myocardial tissue characterization in a one-stop-shop multi-parametric imaging technique. Its unique capability to perform an accurate tissue characterization of the myocardium, which is superior to other imaging modalities, has prompt its use in the analysis of myocardial arrhythmic substrates and in the prognostic risk stratification of patients...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28008358/impact-of-microvascular-obstruction-on-semiautomated-techniques-for-quantifying-acute-and-chronic-myocardial-infarction-by-cardiovascular-magnetic-resonance
#18
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Shane Weinmann, Alex Sirker, Anna S Herrey, Charlotte Manisty, James C Moon, Derek J Hausenloy
AIMS: The four most promising semiautomated techniques (5-SD, 6-SD, Otsu and the full width half maximum (FWHM)) were compared in paired acute and follow-up cardiovascular magnetic resonance (CMR), taking into account the impact of microvascular obstruction (MVO) and using automated extracellular volume fraction (ECV) maps for reference. Furthermore, their performances on the acute scan were compared against manual myocardial infarct (MI) size to predict adverse left ventricular (LV) remodelling (≥20% increase in end-diastolic volume)...
2016: Open Heart
https://www.readbyqxmd.com/read/28003965/a-method-to-implement-the-reservoir-wave-hypothesis-using-phase-contrast-magnetic-resonance-imaging
#19
Robert D M Gray, Kim H Parker, Michael A Quail, Andrew M Taylor, Giovanni Biglino
The reservoir-wave hypothesis states that the blood pressure waveform can be usefully divided into a "reservoir pressure" related to the global compliance and resistance of the arterial system, and an "excess pressure" that depends on local conditions. The formulation of the reservoir-wave hypothesis applied to the area waveform is shown, and the analysis is applied to area and velocity data from high-resolution phase-contrast cardiovascular magnetic resonance (CMR) imaging. A validation study shows the success of the principle, with the method producing largely robust and physically reasonable parameters, and the linear relationship between flow and wave pressure seen in the traditional pressure formulation is retained...
2016: MethodsX
https://www.readbyqxmd.com/read/28000002/stress-perfusion-magnetic-resonance-imaging-to-detect-coronary-artery-lesions-in-children
#20
Chodchanok Vijarnsorn, Michelle Noga, Daryl Schantz, Dion Pepelassis, Edythe B Tham
BACKGROUND: Stress perfusion cardiovascular magnetic resonance (CMR) is used widely in adult ischemic heart disease, but data in children is limited. We sought to evaluate feasibility, accuracy and prognostic value of stress CMR in children with suspected coronary artery disease (CAD). METHODS: Stress CMR was reviewed from two pediatric centers over 5 years using a standard pharmacologic protocol. Wall motion abnormalities, perfusion deficits and late enhancement were correlated with coronary angiogram (CAG) when available, and clinical status at 1 year follow-up for major adverse cardiovascular events (MACE; coronary revascularization, non-fatal myocardial infarction and death due to CAD) was recorded...
December 20, 2016: International Journal of Cardiovascular Imaging
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