keyword
https://read.qxmd.com/read/38716171/effects-of-lactobacillus-plantarum-l-and-molasses-m-on-nutrient-composition-aerobic-stability-and-microflora-of-alfalfa-silage-in-sandy-grasslands
#1
JOURNAL ARTICLE
Wen Peng, Liyuan Zhang, Manlin Wei, Baiyila Wu, Ming Xiao, Runze Zhang, Ji Ju, Chenyang Dong, Liu Du, Yongjie Zheng, Meili Bao, Hailin Bao, Xiaoping Bao
The objective of this experiment was to investigate the effects of Lactobacillus plantarum and molasses on the nutrient composition, fermentation quality, bacterial count, aerobic stability, and microflora of alfalfa silage in sandy grasslands. The experimental treatments included control (CK), 106 CFU/g Lactobacillus plantarum (L), 5% molasses (M), and 106 CFU/g Lactobacillus plantarum + 5% molasses (LM). The nutrient composition, fermentation quality, bacterial count, aerobic stability, and microflora were determined after 14 days and 56 days of ensiling, respectively...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38711365/clinical-value-of-circulating-tumour-cells-in-evaluating-the-efficacy-of-continuous-hepatic-arterial-infusion-among-colorectal-cancer-patients
#2
JOURNAL ARTICLE
Erying Zhang, Haifei Li, Caiyun Liu, Haikun Zhou, Bo Liu, Chengbao Feng
Few studies have been conducted to evaluate the efficacy of HAIC using circulating tumour cells (CTCs). In this study, a total of 100 patients who received HAIC treatment and CTC detection were selected. The results showed that after HAIC treatment, the levels of CTC, carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) decreased. Postoperative progression-free survival (PFS) rates between patients with positive and negative preoperative CTC results, and for CA19-9, CEA were significantly different...
May 6, 2024: Journal of Chemotherapy
https://read.qxmd.com/read/38699139/carbohydrate-antigen-ca-19-9-surge-unraveling-the-enigma-of-elevated-levels-in-the-setting-of-benign-etiologies
#3
Nida Ansari, Sacide S Ozgur, Damian Besada, Noor Bittar, Gabriel Melki, Kanthi Badipatla, Derick Christian, Yana Cavanagh
Carbohydrate antigen 19-9 (CA 19-9) is widely recognized as a tumor marker primarily associated with pancreatic cancer. However, its elevation in benign pancreaticobiliary conditions complicates its diagnostic utility. We present the case of a 39-year-old male with no significant medical history who presented with symptoms of abdominal pain, nausea, vomiting, and diarrhea. The initial diagnosis suggested viral enteritis, but the subsequent worsening of symptoms led to further investigation. Elevated white blood cell counts, bilirubin levels, and liver function tests prompted magnetic resonance cholangiopancreatography (MRCP), which revealed dilated bile ducts and acute cholecystitis...
April 2024: Curēus
https://read.qxmd.com/read/38693738/diabulimia-and-type-1-diabetes-an-unknown-and-emerging-problem
#4
JOURNAL ARTICLE
Benedetta Rivolta, Benedetta Masserini, Irene Bernardi, Antonella Camera, Federico Liboà, Sebastiano Bruno Solerte, Chiara Cerabolini, Nadia Cerutti
BACKGROUND: T1DM patients have a higher prevalence of eating disorders than the general population, and up to 30-40% of young T1DM patients suffer from an eating disorder, including diabulimia. Eating disorders worsen glycemic control and make insulin therapy management more difficult. Closed loop systems (HCLS) allow major therapeutic flexibility; however, proper carbohydrate (CHO) counting remains a fundamental feature for insulin dose adjustments. CASE REPORT: A 30-year-old female patient affected by T1DM (with a past medical history of drug abuse and depressive syndrome) presented with inadequate glycemic control and prandial boli management...
April 30, 2024: Endocrine, Metabolic & Immune Disorders Drug Targets
https://read.qxmd.com/read/38682598/accuracy-and-feasibility-of-using-a-smartphone-application-for-carbohydrate-counting-versus-traditional-carbohydrate-counting-for-adults-with-insulin-treated-diabetes
#5
JOURNAL ARTICLE
Mohammad Shehab, Robert M Cohen, Bonnie Brehm, Tamilyn Bakas
BACKGROUND: Patients with insulin-treated diabetes struggle with performing accurate carbohydrate counting for proper blood glucose control. Little is known about the comparative accuracy and feasibility of carbohydrate counting methods. PURPOSE: The purpose of this study was to determine whether carbohydrate counting using a smartphone application is more accurate and feasible than a traditional method. THEORETICAL/CONCEPTUAL FRAMEWORK: Based on a conceptual model derived from the Technology Acceptance Model, feasibility was defined as usefulness, ease of use, and behavioral intention to use each method...
April 29, 2024: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/38681278/prevalence-of-overweight-obesity-associated-with-anemia-among-female-medical-students-at-umm-al-qura-university-in-makkah-saudi-arabia-a-cross-sectional-study
#6
JOURNAL ARTICLE
Munerah Hamed, Amal Zaghloul, Saeed H Halawani, Bushra A Fatani, Bashair Alshareef, Aisha Almalki, Esraa Alsharif, Qamar A ALhothaly, Salma Alhadhrami, Hanan M Abd Elmoneim
Introduction The obesity epidemic has been linked to a wide range of health and nutritional problems, including anemia, which is often caused by impaired iron metabolism. The World Health Organization considers anemia and obesity to be global health issues among adolescent girls and women experiencing menstruation. This study aims to examine the association between iron deficiency anemia and obesity/overweight among female medical students. Methodology This cross-sectional descriptive study conducted as an online self-administered questionnaire...
March 2024: Curēus
https://read.qxmd.com/read/38674701/metagenomic-analyses-reveal-gut-microbial-profiles-of-cnaphalocrocis-medinalis-driven-by-the-infection-of-baculovirus-cnmegv
#7
JOURNAL ARTICLE
Chuanming Li, Guangjie Han, Lixin Huang, Yurong Lu, Yang Xia, Nan Zhang, Qin Liu, Jian Xu
The composition of microbiota in the digestive tract gut is essential for insect physiology, homeostasis, and pathogen infection. Little is known about the interactions between microbiota load and oral infection with baculoviruses. CnmeGV is an obligative baculovirus to Cnaphalocrocis medinalis . We investigated the impact of CnmeGV infection on the structure of intestinal microbes of C. medinalis during the initial infection stage. The results revealed that the gut microbiota profiles were dynamically driven by pathogen infection of CnmeGV...
April 9, 2024: Microorganisms
https://read.qxmd.com/read/38648259/ten-years-of-improving-glycemic-control-in-pediatric-diabetes-care-data-from-the-norwegian-childhood-diabetes-registry
#8
JOURNAL ARTICLE
Heiko Bratke, Eva Biringer, Anastasia Ushakova, Hanna D Margeirsdottir, Siv Janne Kummernes, Pål R Njølstad, Torild Skrivarhaug
OBJECTIVE: To evaluate, from 2013 to 2022, how HbA1c, the incidence of acute complications, and use of diabetes technology changed at the national level in Norway and how glycemic control was associated with use of diabetes technology, carbohydrate counting, or participation in a quality improvement project. RESEARCH DESIGN AND METHODS: This longitudinal observational study was based on 27,214 annual registrations of 6,775 children from the Norwegian Childhood Diabetes Registry from 2013 to 2022...
April 22, 2024: Diabetes Care
https://read.qxmd.com/read/38645565/microenvironment-systemic-inflammatory-response-and-tumor-markers-considering-consensus-molecular-subtypes-of-colorectal-cancer
#9
JOURNAL ARTICLE
Anna Jakab, Árpád V Patai, Mónika Darvas, Karolina Tormássi-Bély, Tamás Micsik
Introduction: Colorectal carcinomas (CRC) are one of the most frequent malignancies worldwide. Based on gene expression profile analysis, CRCs can be classified into four distinct subtypes also known as the consensus molecular subtypes (CMS), which predict biological behaviour. Besides CMS, several other aspects of tumor microenvironment (TME) and systemic inflammatory response (SIR) influence the outcome of CRC patients. TME and inflammation have important role in the immune (CMS1) and mesenchymal (CMS4) subtypes, however, the relationship between these and systemic inflammation has not been assessed yet...
2024: Pathology Oncology Research: POR
https://read.qxmd.com/read/38611395/medium-chain-triglyceride-oil-and-dietary-intervention-improved-body-composition-and-metabolic-parameters-in-children-with-glycogen-storage-disease-type-1-in-jordan-a-clinical-trial
#10
JOURNAL ARTICLE
Hadil S Subih, Reem A Qudah, Sana Janakat, Hanadi Rimawi, Nour Amin Elsahoryi, Linda Alyahya
Glycogen storage diseases (GSDs) are a group of carbohydrate metabolism disorders, most of which are inherited in autosomal recessive patterns. GSDs are of two types: those that have to do with liver and hypoglycaemia (hepatic GSDs) and those that are linked to neuromuscular presentation. This study aims to assess the impact of dietary intervention, including medium-chain triglyceride (MCT) oil, on anthropometric measurements, body composition analysis and metabolic parameters among Jordanian children and is expected to be the first in the country...
April 2, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38611323/evaluation-of-the-quality-changes-in-three-commercial-pastourma-samples-during-refrigerated-storage-using-physicochemical-microbiological-and-image-analyses-combined-with-chemometrics
#11
JOURNAL ARTICLE
Eftichia Kritsi, Georgia Ladika, Natalia A Stavropoulou, Marianna Oikonomakou, Alexandros-George Ioannou, Paris Christodoulou, Spyridon J Konteles, Dionisis Cavouras, Vassilia J Sinanoglou
Despite the inherent stability of dried and cured products, such as pastourma, appropriate refrigeration remains essential for preserving their optimal characteristics. This study explored quality and safety characteristics in lamb, beef, and buffalo pastourma during 16-day refrigeration storage after package opening. The comprehensive approach employed Attenuated Total Reflection-Fourier-Transform Infrared (ATR-FTIR) spectroscopy, colorimetry, and image analysis, alongside physicochemical and microbiological analyses, to shed light on these alterations...
March 26, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38603784/intensive-management-from-diagnosis-improves-hba1c-at-12-months-post-diagnosis-results-from-a-prospective-cohort-study-in-children-with-newly-diagnosed-type-1-diabetes
#12
JOURNAL ARTICLE
Caroline Griffin, Erin Roxburgh, Neil Owens, Olivia Sanders, Sharon Walsh, Chloe Hudson, Janet Ferguson, Karen MacKenzie, Martin de Bock
AIMS: To examine the impact of intensive management of type 1 diabetes (T1D) from diagnosis on HbA1c 12 months from diagnosis. METHODS: HbA1c measured 12 months after diagnosis for 70 consecutively newly diagnosed children with T1D following implementation of an intensive management protocol was compared with 70 children consecutively diagnosed immediately pre-implementation. Intensive management involved carbohydrate counting and flexible insulin dosing from first meal with subcutaneous insulin, targeted blood glucose levels from 4-8mmol/L irrespective of time of day, avoidance of twice daily insulin regimen and promotion of continuous glucose monitoring (CGM)...
April 12, 2024: New Zealand Medical Journal
https://read.qxmd.com/read/38602658/simplified-integration-of-optimal-self-management-behaviors-is-associated-with-improved-hba1c-in-patients-with-type-1-diabetes
#13
JOURNAL ARTICLE
C Deng, Y Xie, F Liu, X Tang, L Fan, X Yang, Y Chen, Z Zhou, X Li
PURPOSE: Living with type 1 diabetes requires burdensome and complex daily diabetes self-management behaviors. This study aimed to determine the association between integrated behavior performance and HbA1c, while identifying the behavior with the most significant impact on HbA1c. METHODS: A simple and feasible questionnaire was used to collect diabetes self-management behavior in patients with type 1 diabetes (n = 904). We assessed six dimensions of behavior performance: continuous glucose monitor (CGM) usage, frequent glucose testing, insulin pump usage, carbohydrate counting application, adjustment of insulin doses, and usage of apps for diabetes management...
April 11, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38592281/use-of-advanced-hybrid-closed-loop-system-during-pregnancy-strengths-and-limitations-of-achieving-a-tight-glycemic-control
#14
JOURNAL ARTICLE
Parthena Giannoulaki, Evangelia Kotzakioulafi, Alexandros Nakas, Zisis Kontoninas, Polykarpos Evripidou, Triantafyllos Didangelos
Background : Pregnant women with type 1 diabetes mellitus (T1DM) face an elevated risk of complications for both themselves and their newborns. Experts recommend strict glycemic control. The advanced hybrid closed-loop (AHCL) system, though not officially approved for pregnant T1DM patients, is promising for optimal glycemic control. Methods : We collected CGM metrics, HbA1c levels, insulin pump settings, and doses from a 33-year-old pregnant woman with 23-year history of T1DM from the 6th week of gestation to birth...
March 1, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38581323/clinical-efficacy-and-adverse-effects-of-bevacizumab-in-combination-with-chemotherapy-for-metastatic-colorectal-cancer
#15
JOURNAL ARTICLE
Ying Wei, Rui Jin, Hui Xue, Ruixuan Zhou, Zhijuan Chen
OBJECTIVE: This study aims to investigate the efficacy of bevacizumab (BEV) in combination with chemotherapy for metastatic colorectal cancer (mCRC). METHODS: A cohort of 121 patients diagnosed with mCRC and admitted to our hospital from May 2018 to October 2019 were selected for the study. The control group, comprising 64 patients, received chemotherapy alone, while the research group, consisting of 57 patients, underwent a combination of BEV and chemotherapy. Comparative analyses included an assessment of clinical outcomes, monitoring of tumor markers including Carcinoembryonic Antigen (CEA), Cancer Antigen 74-2 (CA74-2), and Carbohydrate Antigen 19-9 (CA19-9) before and after treatment, and a count of adverse effects during the treatment phase...
April 5, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38545175/phytochemical-screening-antioxidant-immunomodulatory-and-analgesic-potential-of-aqueous-ethanolic-extracts-of-euphorbia-prostrata-ait-and-crotalaria-burhia-buch-ham
#16
JOURNAL ARTICLE
Muhammad Rahil Aslam, Hafiz Muhammad Asif, Abdulaziz Alamri, Adnan Ahmed Bhutto, Muhammad Mukhtiar, Khalil Ahmad, Mehak Muhammad Ashfaq, Hafiz Abdul Sattar, Abdul Hayee, Sana Jabbar, Rabia Zahid, Allah Nawaz
Euphorbia prostrata ( E. prostrata ) and Crotalaria burhia ( C. burhia ) are widely found in flora of the Cholistan Desert of Bahawalpur, Pakistan and are traditionally used to treat pain and chronic disease. The current study aimed to evaluate their phytochemical screening, antioxidant activity, in-vivo phagocytic activity, and analgesic activity. Both the plant extracts were investigated for phytochemical screening, Fourier Transform Infrared (FTIR) analysis, in-vitro antioxidant by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method, in-vivo immunomodulatory activity by macrophages phagocytosis using carbon clearance rate assay and analgesic activity by acetic acid produced writhing method...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38538400/prognostic-usefulness-of-the-c-reactive-protein-albumin-lymphocyte-cally-index-as-a-novel-biomarker-in-patients-undergoing-colorectal-cancer-surgery
#17
JOURNAL ARTICLE
Yasuhiro Takeda, Hiroshi Sugano, Atsuko Okamoto, Takafumi Nakano, Yuya Shimoyama, Naoki Takada, Yuta Imaizumi, Masahisa Ohkuma, Makoto Kosuge, Ken Eto
BACKGROUND: The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index is a novel immuno-nutritional biomarker based on the levels of CRP, serum albumin, and lymphocyte count. This study examined the prognostic value of the CALLY index in patients with colorectal cancer undergoing curative surgery. METHODS: Between 2010 and 2017, 578 patients with stage II-III colorectal cancer who underwent curative resection were enrolled. The CALLY index was defined as (albumin × lymphocyte)/(CRP × 104 )...
March 26, 2024: Asian Journal of Surgery
https://read.qxmd.com/read/38500532/an-elisa-based-method-for-galleria-mellonella-apolipophorin-iii-quantification
#18
JOURNAL ARTICLE
Uriel Ramírez-Sotelo, Laura C García-Carnero, José A Martínez-Álvarez, Manuela Gómez-Gaviria, Héctor Manuel Mora-Montes
Mammalian models, such as murine, are used widely in pathophysiological studies because they have a high degree of similarity in body temperature, metabolism, and immune response with humans. However, non-vertebrate animal models have emerged as alternative models to study the host-pathogen interaction with minimal ethical concerns. Galleria mellonella is an alternative model that has proved useful in studying the interaction of the host with either bacteria or fungi, performing drug testing, and assessing the immunological response to different microorganisms...
2024: PeerJ
https://read.qxmd.com/read/38498240/the-inflammation-score-predicts-the-prognosis-of-gastric-cancer-patients-undergoing-da-vinci-robot-surgery
#19
JOURNAL ARTICLE
Xihao Chen, Yichao Zhang, Zhiyu Liu, Jiawei Song, Jipeng Li
Neutrophil-to-lymphocyte ratio (NLR), calculated from peripheral blood immune-inflammatory cell counts, is considered a predictor of survival in various cancers. Nevertheless, there is a lack of research into the predictive value of NLR specifically in gastric cancer patients following surgery using the Da Vinci robot. Investigate the objectives of this research, confirm the positive predictive value of NLR in the prognosis of gastric cancer patients undergoing Da Vinci robotic-assisted surgery by comparing its prognostic ability with other inflammation markers and tumor biomarkers...
March 18, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38492706/a-data-mining-approach-to-analyze-the-role-of-biomacromolecules-based-nanocomposites-in-sustainable-packaging
#20
JOURNAL ARTICLE
John Paul, Jeeja Jacob, Md Mahmud, Mahesh Vaka, Syam G Krishnan, A Arifutzzaman, Dignesh Thesiya, Teng Xiong, K Kadirgama, Jeyraj Selvaraj
Recent decades have witnessed a surge in research interest in bio-nanocomposite-based packaging materials, but still, a lack of systematic analysis exists in this domain. Bio-based packaging materials pose a sustainable alternative to petroleum-based packaging materials. The current work employs bibliometric analysis to deliver a comprehensive outline on the role of bio nanocomposites in packaging. India, Iran, and China were revealed to be the top three nations actively engaged in this domain in total publications...
March 14, 2024: International Journal of Biological Macromolecules
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