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https://www.readbyqxmd.com/read/29779616/sleep-apnea-and-sleep-disordered-breathing
#1
REVIEW
Jiahui Lin, Maria Suurna
Older adults undergo gradual changes in their sleep patterns. It is important to differentiate normal age-related sleep changes from sleep disorders. Because sleep disorders can impact an older adult's day-to-day life and contribute to various comorbidities, these patients should be carefully screened by using a detailed medical history, combined with a detailed sleep history. There is a high prevalence of undiagnosed and untreated sleep apnea in the elderly. Early identification and appropriate management of this disorder may not only provide improvement in quality of life but also decrease disease-associated morbidity and mortality...
May 17, 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29771333/multiple-comorbid-conditions-sleep-quality-and-duration-and-academic-performance-in-urban-children-with-asthma
#2
Katharine C Reynolds, Julie Boergers, Sheryl J Kopel, Daphne Koinis-Mitchell
Objective: Common comorbid medical conditions including allergic rhinitis (AR), obesity, and sleep disordered breathing (SDB) have been linked with asthma exacerbations; however, these conditions also impact sleep and academic functioning. The current study sought to examine unique and combined associations of these common comorbidities on sleep and academic performance among urban minority children with persistent asthma. We expected additional comorbid diagnoses would be associated with poorer sleep and academic functioning...
May 15, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29769049/sleep-disordered-breathing-in-patients-with-newly-diagnosed-lung-cancer
#3
Michael Dreher, Stefan Krüger, Susanne Schulze-Olden, András Keszei, Jan Hendrik Storre, Holger Woehrle, Michael Arzt, Tobias Müller
BACKGROUND: There are currently no data on the prevalence of sleep-disordered breathing (SDB) in patients with newly-diagnosed lung cancer. This might be of interest given that SDB is associated with increased cancer incidence and mortality. Furthermore, intermittent hypoxia has been linked with tumor growth and progression. The aim of the current study was to investigate the prevalence of SDB in patients with newly-diagnosed lung cancer. METHODS: Patients with newly-diagnosed lung cancer from three centers in Germany were screened for SDB using a two-channel screening system (ApneaLink™)...
May 16, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29766929/sleep-disorders-in-amyotrophic-lateral-sclerosis-a-questionnaire-based-study-from-india
#4
Samhita Panda, Mandaville Gourie-Devi, Ankkita Sharma
Background: Amyotrophic lateral sclerosis (ALS) is a relatively rare neurological disorder affecting upper and lower motor neurons in the brain and spinal cord with survival for 3-5 years and rarely beyond 10 years. Sleep disturbances in ALS are underreported and undertreated and there is no related data from India. This study aimed to assess the frequency of sleep disorders in patients of ALS and their determinants. Methods: Patients with definite and probable ALS as per the El Escorial criteria were recruited from May 2014 to April 2016...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29766677/sleeping-child-neuroendocrine-cell-hyperplasia-of-infancy-and-polysomnography
#5
Deborah R Liptzin, Stephen M M Hawkins, Brandie D Wagner, Robin R Deterding
OBJECTIVES: Neuroendocrine cell hyperplasia of infancy (NEHI) is a children's interstitial and diffuse lung disease of unknown etiology that presents in infancy with characteristic findings of tachypnea, retractions, crackles, and hypoxemia. At the present, the mainstay of treatment is oxygen supplementation to normalize oxygen saturations and decrease work of breathing. There are characteristic pulmonary function, radiographic, and histologic findings, but polysomnography (PSG) data has not been reported...
May 15, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29764215/myotonic-dystrophytype-1-report-of-non-24-h-sleep-wake-disorder-with-excessive-daytime-sleepiness
#6
Lucio Huebra Pimentel Filho, Ana Carolina Dias Gomes, Bruno Gonçalves, Sergio Tufik, Fernando Morgadinho Coelho
Myotonic dystrophy (MD) is a neuromuscular disease with myotonia, progressive weakness, and involvement of CNS, heart, and gastrointestinal system. Excessive daytime sleepiness (EDS) in myotonic dystrophy type 1 (MD1) is related to sleep breathing diseases, restless leg syndrome, periodic limb movements during sleep and narcoleptic-like phenotype. However, authors highlight a central dysfunction of sleep regulation. We describe a 26-year-old, female, MD1 patient with EDS. Sleep diary/actigraphy evidenced two different circadian periods with values of 1442 and 1522 min...
May 15, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29759277/effects-of-chronic-opioid-use-on-sleep-and-wake
#7
REVIEW
Michelle Cao, Shahrokh Javaheri
Chronic use of opioids negatively affects sleep on 2 levels: sleep architecture and breathing. Patients suffer from a variety of daytime sequelae. There may be a bidirectional relationship between poor sleep quality, sleep-disordered breathing, and daytime function. Opioids are a potential cause of incident depression. The best therapeutic option is withdrawal of opioids, which proves difficult. Positive airway pressure devices are considered first-line treatment for sleep-related breathing disorders. New generation positive pressure servo ventilators are increasingly popular as a treatment option for opioid-induced sleep-disordered breathing...
June 2018: Sleep Medicine Clinics
https://www.readbyqxmd.com/read/29746662/impact-of-sleep-characteristics-and-obesity-on-diabetes-and-hypertension-across-genders-and-menopausal-status-the-nagahama-study
#8
Takeshi Matsumoto, Kimihiko Murase, Yasuharu Tabara, David Gozal, Dale Smith, Takuma Minami, Ryo Tachikawa, Kiminobu Tanizawa, Toru Oga, Shunsuke Nagashima, Tomoko Wakamura, Naoko Komenami, Kazuya Setoh, Takahisa Kawaguchi, Takanobu Tsutsumi, Yoshimitsu Takahashi, Takeo Nakayama, Toyohiro Hirai, Fumihiko Matsuda, Kazuo Chin
Study Objectives: The individual prevalence of sleep-disordered breathing (SDB), short sleep duration, and obesity is high and increasing. The study aimed to investigate potential associations between SDB, objective sleep duration, obesity, diabetes and hypertension across genders, and the effect of pre- or post-menopausal status. Methods: A cross-sectional study evaluated 7051 community participants with wrist actigraphy for a week, and nocturnal oximetry ≥ 2 nights...
May 9, 2018: Sleep
https://www.readbyqxmd.com/read/29746147/female-sex-and-gender-in-lung-sleep-health-and-disease-increased-understanding-of-basic-biological-pathophysiological-and-behavioral-mechanisms-leading-to-better-health-for-female-patients-with-lung-disease
#9
MeiLan K Han, Emilio Arteaga-Solis, John Blenis, Ghada Bourjeily, Deborah J Clegg, Dawn DeMeo, Jeanne Duffy, Ben Gaston, Nicola M Heller, Anna Hemnes, Elizabeth Petri Henske, Raksha Jain, Tim Lahm, Lisa H Lancaster, Joyce Lee, Marianne J Legato, Sherry McKee, Reena Mehra, Alison Morris, Y S Prakash, Martin R Stampfli, Rashmi Gopal-Srivastava, Aaron D Laposky, Antonello Punturieri, Lora Reineck, Xenia Tigno, Janine Clayton
Female sex/gender is an under-characterized variable in studies related to lung development and disease. Notwithstanding, many aspects of lung and sleep biology and pathobiology are impacted by female sex and female reproductive transitions. These may manifest as differential gene expression or peculiar organ development. Some conditions are more prevalent in women, such as asthma and insomnia, or in the case of LAM, are seen almost exclusively in women. In other diseases, presentation differs such as the higher frequency of exacerbations experienced by women with COPD or greater cardiac morbidity among women with sleep disordered breathing...
May 10, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29739536/opioids-respiratory-depression-and-sleep-disordered-breathing
#10
REVIEW
Mahesh Nagappa, Toby N Weingarten, Gaspard Montandon, Juraj Sprung, Frances Chung
The increasing use of opioids in the perioperative period has increased opioid-associated morbidity and mortality. There is a well-established connection between opioids, sleep-disordered breathing (SDB), and respiratory depression. The treatment of postoperative pain with opioids in patients with SDB may result in respiratory depression. In an unmonitored setting, it may lead to life-threatening respiratory events. More studies are required to evaluate the effective management and prevention of respiratory depression in patients with SDB...
December 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29734992/lack-of-worsening-of-sleep-disordered-breathing-after-recurrent-stroke-in-the-basic-project
#11
Devin L Brown, Chengwei Li, Brisa N Sánchez, Galit Levi Dunietz, Ronald D Chervin, Erin Case, Nelda M Garcia, Lynda D Lisabeth
STUDY OBJECTIVES: To investigate the difference in sleep-disordered breathing (SDB) prevalence and severity after an index and recurrent stroke. METHODS: In a sample of 40 subjects, home sleep apnea tests were performed a median of 10 days after an index ischemic stroke and 14 days after a recurrent ischemic stroke. A respiratory event index (REI) of ≥ 10 events/h (apneas plus hypopneas per hour of recording) was used to define clinically significant SDB. The relative difference in REI or relative SDB prevalence was used to compare the post-recurrent stroke measurement with that made after the index stroke, and was expressed as a rate ratio (RR) or prevalence ratio (PR)...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29729860/is-ventilatory-therapy-combined-with-exercise-training-effective-in-patients-with-heart-failure-and-sleep-disordered-breathing-results-of-a-randomized-trial-during-a-cardiac-rehabilitation-programme-satelit-hf
#12
Marie-Christine Iliou, Sonia Corone, Barnabas Gellen, Thierry Denolle, Frederic Roche, Anaïs Charles Nelson, Christian Darné
BACKGROUND: Sleep-related disordered breathing is common in patients with chronic heart failure. AIM: To assess the efficacy of short-term nocturnal ventilatory therapy combined with exercise training (V+ET) compared with exercise training alone (ET) in patients with chronic heart failure with sleep-disordered breathing. METHODS: Patients in New York Heart Association functional class II-IIIb, with an apnoea-hypopnoea index (AHI)>15/h, and enrolled in a cardiac rehabilitation programme, were centrally randomized to V+ET or ET...
May 2, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29728165/influence-of-age-and-gender-on-reference-values-for-common-pediatric-sleep-questionnaires-results-from-a-community-based-study
#13
Pablo E Brockmann, Tobias Peters, Christian F Poets, Barbara Wilhelm, Veronika Weyer-Elberich, Michael S Urschitz
OBJECTIVES: Sleep problems are often assessed using questionnaires, but it is unclear whether the responses given are influenced by age and gender. We addressed this question in several widely used pediatric sleep questionnaires and provide age-dependent percentile curves. METHODS: Data of a community-based study in schoolchildren were reanalyzed (N = 163, 50% males, age 6-17 years). Children and their parents completed the Sleep-Related Breathing Disorder Scale (SRBDS) of the Pediatric Sleep Questionnaire, the Sleep Disturbance Scale for Children (SDSC), the Sleep Self Report (SSR) of the Children's Sleep Habits Questionnaire in a long and short version, the Epworth Sleepiness Scale in a parent- (ESSp) and self-report version for children (ESSc), and the Pediatric Daytime Sleepiness Scale (PDSS)...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29719025/correlation-between-excessive-daytime-sleepiness-eds-and-self-reported-and-objective-nasal-characteristics
#14
K M Hoven, H J Aarstad, B Bjorvatn, E H Lundemo, S K Steinsvåg
BACKGROUND: The aim of the present study was to explore the relationship between excessive daytime sleepiness (EDS), Peak Nasal Inspiratory Flow (PNIF), and patient reported symptoms from the nose. METHOLOGY: Six hundred and fifty one consecutive patients referred to a hospital on suspicion of sleep related breathing disorder (SRBD) were included in the study. Daytime sleepiness was assessed by Epworth Sleepiness Scale (EpSS). Nasal airflow was measured with Peak Nasal Inspiratory Flow (PNIF)...
April 25, 2018: Rhinology
https://www.readbyqxmd.com/read/29717414/primary-central-sleep-apnea-and-anesthesia-a-retrospective-case-series
#15
Alexandru Alexa, Meghna P Mansukhani, Bhargavi Gali, Atousa Deljou, Juraj Sprung, Toby N Weingarten
PURPOSE: Primary (idiopathic) central sleep apnea (PCSA) is a rare central sleep-related breathing disorder characterized by increased chemoreceptor sensitivity to partial pressure of carbon dioxide, which manifests as hyperventilation followed by apnea during non-rapid eye movement sleep. The purpose of this retrospective study was to describe the postoperative course of patients who had PCSA and underwent procedures requiring anesthetic management. METHODS: Patients who received a diagnosis of PCSA at our institution and required procedural anesthesia between 1 January 2010 and 1 June 2016 underwent a comprehensive review of their health records with a focus on identifying respiratory complications...
May 1, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29702204/chronic-intermittent-hypoxia-induces-changes-on-the-expression-and-activity-of-neprilysin-ec-3-4-24-16-in-the-brain-of-rats
#16
Renato W de Oliveira, Guilherme S Julian, Juliana C Perry, Sergio Tufik, Jair R Chagas
Obstructive sleep apnea (OSA) is a frequent sleeping breathing disorder associated with cognitive impairments. Neprilysin (NEP) is responsible for degrading several substrates related to cognition; however, the effect of chronic intermittent hypoxia (CIH) on NEP is still unknown. This study aimed to evaluate the expression and activity of NEP under CIH in cognitive-related brain structures. Western blot, qRT-PCR and enzyme activity assay, demonstrated that a six-week intermittent hypoxia increased NEP expression and activity, selectively in temporal cortex, but not in the hippocampus and frontal cortex...
April 24, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29687190/monitoring-healthy-and-disturbed-sleep-through-smartphone-applications-a-review-of-experimental-evidence
#17
REVIEW
Edita Fino, Michela Mazzetti
Smartphone applications are considered as the prime candidate for the purposes of large-scale, low-cost and long-term sleep monitoring. How reliable and scientifically grounded is smartphone-based assessment of healthy and disturbed sleep remains a key issue in this direction. Here we offer a review of validation studies of sleep applications to the aim of providing some guidance in terms of their reliability to assess sleep in healthy and clinical populations, and stimulating further examination of their potential for clinical use and improved sleep hygiene...
April 23, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29684317/portable-sleep-monitoring-for-diagnosing-sleep-apnea-in-hospitalized-patients-with-heart-failure
#18
R Nisha Aurora, Susheel P Patil, Naresh M Punjabi
BACKGROUND: Sleep apnea is an underdiagnosed condition in patients with heart failure. Efficient identification of sleep apnea is needed as treatment may improve heart failure-related outcomes. Currently, use of portable sleep monitoring in hospitalized patients and those at risk for central sleep apnea is discouraged. This study examined if portable sleep monitoring with respiratory polygraphy can accurately diagnose sleep apnea in patients hospitalized with decompensated heart failure...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684315/sleep-disorders-in-patients-with-post-traumatic-stress-disorder
#19
REVIEW
Ali A El-Solh, Usman Riaz, Jasmine Roberts
A growing body of evidence supports a bidirectional relationship between post-traumatic stress disorder (PTSD) and sleep disturbances. Fragmented sleep induced by sleep-related breathing disorders, insomnia, and nightmares impacts recovery and treatment outcomes and worsens PTSD symptoms. Despite recent attention, management of these disorders has been unrewarding in the setting of PTSD. This review summarizes the evidence for empirically supported treatments of these sleep ailments as it relates to PTSD including psychotherapeutic and pharmacologic interventions...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29680416/electrocardiographic-variables-in-children-with-syndromic-craniosynostosis-and-primary-snoring-to-mild-obstructive-sleep-apnea-significance-of-identifying-respiratory-arrhythmia-during-sleep
#20
Ellaha Kakar, Linda J A Corel, Robert C Tasker, Robbin de Goederen, Eppo B Wolvius, Irene M J Mathijssen, Koen F M Joosten
BACKGROUND: In the spectrum of children with symptomatic sleep disordered breathing (SDB), some individuals - such as those with upper airway resistance syndrome (UARS) - do not have abnormalities on polysomnography (PSG). In this study we have assessed whether assessment of respiratory arrhythmia (RA) and heart rate variability (HRV) analysis helps in management of children with syndromic craniosynostosis and none-to-mild obstructive sleep apnea (OSA). METHODS: Prospective cohort study in children aged 1-18 years old with syndromic craniosynostosis...
May 2018: Sleep Medicine
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