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https://www.readbyqxmd.com/read/28524546/inflammatory-bowel-disease-is-presenting-sooner-after-immigration-in-more-recent-us-immigrants-from-cuba
#1
O M Damas, D J Avalos, A M Palacio, L Gomez, M A Quintero, A R Deshpande, D A Sussman, J L McCauley, J Lopez, S J Schwartz, M T Abreu
BACKGROUND: Despite a rising incidence of inflammatory bowel disease (IBD) in Hispanics in the United States, there are no studies examining the relationship between immigrant generation and IBD onset among Hispanics. AIMS: To determine whether age of IBD diagnosis, time from immigration to IBD diagnosis and IBD phenotype, differed across immigration periods in South Florida Cuban immigrants. METHODS: This was a cohort of consecutively identified Cuban-born adults who developed IBD in the United States and were followed in gastroenterology (GI) clinic...
May 19, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28521026/tracking-career-paths-of-women-in-neurosurgery
#2
Jaclyn J Renfrow, Analiz Rodriguez, Taylor A Wilson, Isabelle M Germano, Aviva Abosch, Stacey Quintero Wolfe
BACKGROUND: Women represent a growing cohort of US neurosurgeons. OBJECTIVE: To describe postresidency fellowship, practice environment, and updated academic rank among female neurosurgeons. METHODS: Databases from the American Association of Neurological Surgeons (AANS) and the American Board of Neurological Surgery (ABNS) from 1964 to 2013 were reviewed for female neurosurgery residency graduates. Data on postresidency fellowships, practice environment (private vs academic), academic rank, board certification, and AANS/CNS (Congress of Neurological Surgeons) Joint Section on Women in Neurosurgery (WINS) membership were collected in 2016...
May 16, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28518111/using-enzyme-based-biosensors-to-measure-tonic-and-phasic-glutamate-in-alzheimer-s-mouse-models
#3
Holly C Hunsberger, Sharay E Setti, Ryan T Heslin, Jorge E Quintero, Greg A Gerhardt, Miranda N Reed
Neurotransmitter disruption is often a key component of diseases of the central nervous system (CNS), playing a role in the pathology underlying Alzheimer's disease, Parkinson's disease, depression, and anxiety. Traditionally, microdialysis has been the most common (lauded) technique to examine neurotransmitter changes that occur in these disorders. But because microdialysis has the ability to measure slow 1-20 minute changes across large areas of tissue, it has the disadvantage of invasiveness, potentially destroying intrinsic connections within the brain and a slow sampling capability...
May 3, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28500802/high-resolution-melting-curve-analysis-of-the-16s-ribosomal-gene-to-detect-and-identify-pathogenic-and-saprophytic-leptospira-species-in-colombian-isolates
#4
Ronald G Peláez Sánchez, Juan Álvaro López Quintero, Martha María Pereira, Piedad Agudelo-Flórez
AbstractIt is important to identify the circulating Leptospira agent to enhance the performance of serodiagnostic tests by incorporating specific antigens of native species, develop vaccines that take into account the species/serovars circulating in different regions, and optimize prevention and control strategies. The objectives of this study were to develop a polymerase chain reaction (PCR)-high-resolution melting (HRM) assay for differentiating between species of the genus Leptospira and to verify its usefulness in identifying unknown samples to species level...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28490103/speciation-analysis-of-organoarsenic-compounds-in-livestock-feed-by-microwave-assisted-extraction-and-high-performance-liquid-chromatography-coupled-to-atomic-fluorescence-spectrometry
#5
A A Saucedo-Velez, L Hinojosa-Reyes, M Villanueva-Rodríguez, A Caballero-Quintero, A Hernández-Ramírez, J L Guzmán-Mar
The development of a new method to determine the presence of the organoarsenic additives p-arsanilic acid (ASA), roxarsone (ROX) and nitarsone (NIT) in livestock feeds by high performance liquid chromatography coupled to ultraviolet oxidation hydride generation atomic fluorescence spectrometry (HPLC-UV/HG-AFS) after microwave assisted extraction (MAE) was proposed. Chromatographic separation was achieved on a C18 column with 2% acetic acid/methanol (96:4, v/v) as the mobile phase. The limits of detection (LODs) were 0...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28486355/air-abrasive-disinfection-of-implant-surfaces-in-a-simulated-model-of-periimplantitis
#6
David George Quintero, Robert Bonnie Taylor, Matthew Braden Miller, Keith Roshanali Merchant, Scott Anthony Pasieta
INTRODUCTION: This in vitro study aimed to evaluate the ability of air-powder abrasion to decontaminate dental implants. MATERIALS AND METHODS: Twenty-six implants were inoculated with a Streptococcus sanguinis biofilm media in a novel periimplantitis defect model. Six implants served as controls, and 20 implants were disinfected with either the Cavitron JET Plus or the AIR-FLOW PERIO air-powder abrasion units. Residual bacteria were cultured, and colony forming units (CFUs) were totaled at 24 hours...
May 6, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28464932/interaction-between-fto-rs9939609-and-the-native-american-origin-abca1-rs9282541-affects-bmi-in-the-admixed-mexican-population
#7
Marisela Villalobos-Comparán, Bárbara Antuna-Puente, María Teresa Villarreal-Molina, Samuel Canizales-Quinteros, Rafael Velázquez-Cruz, Paola León-Mimila, Hugo Villamil-Ramírez, Juan Antonio González-Barrios, José Luis Merino-García, María Rocío Thompson-Bonilla, Diego Jarquin, Osvaldo Erik Sánchez-Hernández, Martha Eunice Rodríguez-Arellano, Carlos Posadas-Romero, Gilberto Vargas-Alarcón, Francisco Campos-Pérez, Manuel Quiterio, Jorge Salmerón-Castro, Alessandra Carnevale, Sandra Romero-Hidalgo
BACKGROUND: The aim of this study was to explore whether interactions between FTO rs9939609 and ABCA1 rs9282541 affect BMI and waist circumference (WC), and could explain previously reported population differences in FTO-obesity and FTO-BMI associations in the Mexican and European populations. METHODS: A total of 3938 adults and 636 school-aged children from Central Mexico were genotyped for both polymorphisms. Subcutaneous and visceral adipose tissue biopsies from 22 class III obesity patients were analyzed for FTO and ABCA1 mRNA expression...
May 2, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28460908/gc-ms-method-to-quantify-bioavailable-phenolic-compounds-and-antioxidant-capacity-determination-of-plasma-after-acute-coffee-consumption-in-human-volunteers
#8
Oscar Javier Lara-Guzmán, Rafael Álvarez-Quintero, Edison Osorio, Mauricio Naranjo-Cano, Katalina Muñoz-Durango
Coffee, a source of chlorogenic acids (CGAs), is recognized for preventing chronic diseases associated with oxidative stress. Therefore, sensitive, selective and easy access methods for the determination of the bioavailability and antioxidant function in vivo are required in clinical studies. The aim of this work was to validate a GC/MS method to quantify caffeic acid (CA) and ferulic acid (FA) and to apply different methodologies to determine the antioxidant capacity of plasma after the acute consumption of 420mg of CGAs provided by 400mL of coffee...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28459047/barriers-to-clinical-research-in-latin-america
#9
Kathryn Chomsky-Higgins, Theodore A Miclau, Madeline C Mackechnie, Dino Aguilar, Jorge Rubio Avila, Fernando Baldy Dos Reis, Roberto Balmaseda, Antonio Barquet, Alfredo Ceballos, Fernando Contreras, Igor Escalante, Nelson Elias, Sergio Iriarte Vincenti, Christian Lozano, Fryda Medina, Gavino Merchan, Julio Segovia, Enrique Guerado, Jose Eduardo Quintero, Saam Morshed, Mohit Bhandari, Theodore Miclau
Enhancing health research capacity in developing countries is a global health priority. Understanding the orthopedic burden of disease in Latin America will require close partnership between more-developed and less-developed countries. To this end, the Osteosynthesis and Trauma Care Foundation assembled a research consortium of Latin-American orthopedic leaders. Prior to the meeting, we surveyed attendees on perceived barriers to conducting research at their institutions. During the event, working groups discussed these barriers, developed strategies for addressing them, and planned future steps for collaboration...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28457582/clinical-and-sociodemographic-profile-of-epilepsy-in-adults-from-a-reference-centre-in-colombia
#10
J P Orozco-Hernández, J F Quintero-Moreno, D S Marín-Medina, J P Castaño-Montoya, P Hernández-Coral, M Pineda, J D Vélez, H C Villada, J W Martínez, A Lizcano
OBJECTIVES: To describe the sociodemographic and clinical characteristics of a cohort of patients with epilepsy from a reference centre in Colombia. METHODS: Cross-sectional study including patients diagnosed with epilepsy who attended our epilepsy centre (Neurocentro) between 2013 and 2016. Data were gathered from patients' medical histories. RESULTS: We gathered data from a total of 354 patients diagnosed with epilepsy. Median age was 37 years; 52% were men...
April 27, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28452534/first-demonstration-of-electrostatic-damping-of-parametric-instability-at-advanced-ligo
#11
Carl Blair, Slawek Gras, Richard Abbott, Stuart Aston, Joseph Betzwieser, David Blair, Ryan DeRosa, Matthew Evans, Valera Frolov, Peter Fritschel, Hartmut Grote, Terra Hardwick, Jian Liu, Marc Lormand, John Miller, Adam Mullavey, Brian O'Reilly, Chunnong Zhao, B P Abbott, T D Abbott, C Adams, R X Adhikari, S B Anderson, A Ananyeva, S Appert, K Arai, S W Ballmer, D Barker, B Barr, L Barsotti, J Bartlett, I Bartos, J C Batch, A S Bell, G Billingsley, J Birch, S Biscans, C Biwer, R Bork, A F Brooks, G Ciani, F Clara, S T Countryman, M J Cowart, D C Coyne, A Cumming, L Cunningham, K Danzmann, C F Da Silva Costa, E J Daw, D DeBra, R DeSalvo, K L Dooley, S Doravari, J C Driggers, S E Dwyer, A Effler, T Etzel, T M Evans, M Factourovich, H Fair, A Fernández Galiana, R P Fisher, P Fulda, M Fyffe, J A Giaime, K D Giardina, E Goetz, R Goetz, C Gray, K E Gushwa, E K Gustafson, R Gustafson, E D Hall, G Hammond, J Hanks, J Hanson, G M Harry, M C Heintze, A W Heptonstall, J Hough, K Izumi, R Jones, S Kandhasamy, S Karki, M Kasprzack, S Kaufer, K Kawabe, N Kijbunchoo, E J King, P J King, J S Kissel, W Z Korth, G Kuehn, M Landry, B Lantz, N A Lockerbie, A P Lundgren, M MacInnis, D M Macleod, S Márka, Z Márka, A S Markosyan, E Maros, I W Martin, D V Martynov, K Mason, T J Massinger, F Matichard, N Mavalvala, R McCarthy, D E McClelland, S McCormick, G McIntyre, J McIver, G Mendell, E L Merilh, P M Meyers, R Mittleman, G Moreno, G Mueller, J Munch, L K Nuttall, J Oberling, P Oppermann, Richard J Oram, D J Ottaway, H Overmier, J R Palamos, H R Paris, W Parker, A Pele, S Penn, M Phelps, V Pierro, I Pinto, M Principe, L G Prokhorov, O Puncken, V Quetschke, E A Quintero, F J Raab, H Radkins, P Raffai, S Reid, D H Reitze, N A Robertson, J G Rollins, V J Roma, J H Romie, S Rowan, K Ryan, T Sadecki, E J Sanchez, V Sandberg, R L Savage, R M S Schofield, D Sellers, D A Shaddock, T J Shaffer, B Shapiro, P Shawhan, D H Shoemaker, D Sigg, B J J Slagmolen, B Smith, J R Smith, B Sorazu, A Staley, K A Strain, D B Tanner, R Taylor, M Thomas, P Thomas, K A Thorne, E Thrane, C I Torrie, G Traylor, G Vajente, G Valdes, A A van Veggel, A Vecchio, P J Veitch, K Venkateswara, T Vo, C Vorvick, M Walker, R L Ward, J Warner, B Weaver, R Weiss, P Weßels, B Willke, C C Wipf, J Worden, G Wu, H Yamamoto, C C Yancey, Hang Yu, Haocun Yu, L Zhang, M E Zucker, J Zweizig
Interferometric gravitational wave detectors operate with high optical power in their arms in order to achieve high shot-noise limited strain sensitivity. A significant limitation to increasing the optical power is the phenomenon of three-mode parametric instabilities, in which the laser field in the arm cavities is scattered into higher-order optical modes by acoustic modes of the cavity mirrors. The optical modes can further drive the acoustic modes via radiation pressure, potentially producing an exponential buildup...
April 14, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28438016/highly-oriented-low-dimensional-tin-halide-perovskites-with-enhanced-stability-and-photovoltaic-performance
#12
Yuqin Liao, Hefei Liu, Wenjia Zhou, Dongwen Yang, Yuequn Shang, Zhifang Shi, Binghan Li, Xianyuan Jiang, Lijun Zhang, Li Na Quan, Rafael Quintero-Bermudez, Brandon R Sutherland, Qixi Mi, Edward H Sargent, Zhijun Ning
The low toxicity and a near-ideal choice of bandgap make tin perovskite an attractive alternative to lead perovskite in low cost solar cells. However, the development of Sn perovskite solar cells has been impeded by their extremely poor stability when exposed to oxygen. We report low-dimensional Sn perovskites that exhibit markedly enhanced air stability in comparison with their 3D counterparts. The reduced degradation under air exposure is attributed to the improved thermodynamic stability after dimensional reduction, the encapsulating organic ligands, and the compact perovskite film preventing oxygen ingress...
May 2, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28431491/fluoride-varnishes-containing-sodium-trimetaphosphate-reduce-enamel-demineralization-in-vitro
#13
Michele M Manarelli, Alberto C B Delbem, Liliana Carolina Báez-Quintero, Felipe Ricardo N de Moraes, Robson F Cunha, Juliano P Pessan
OBJECTIVE: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro. MATERIAL AND METHODS: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group...
April 21, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28424516/slamf7-is-critical-for-phagocytosis-of-haematopoietic-tumour-cells-via-mac-1-integrin
#14
Jun Chen, Ming-Chao Zhong, Huaijian Guo, Dominique Davidson, Sabrin Mishel, Yan Lu, Inmoo Rhee, Luis-Alberto Pérez-Quintero, Shaohua Zhang, Mario-Ernesto Cruz-Munoz, Ning Wu, Donald C Vinh, Meenal Sinha, Virginie Calderon, Clifford A Lowell, Jayne S Danska, André Veillette
Cancer cells elude anti-tumour immunity through multiple mechanisms, including upregulated expression of ligands for inhibitory immune checkpoint receptors. Phagocytosis by macrophages plays a critical role in cancer control. Therapeutic blockade of signal regulatory protein (SIRP)-α, an inhibitory receptor on macrophages, or of its ligand CD47 expressed on tumour cells, improves tumour cell elimination in vitro and in vivo, suggesting that blockade of the SIRPα-CD47 checkpoint could be useful in treating human cancer...
April 27, 2017: Nature
https://www.readbyqxmd.com/read/28415781/relevance-of-dna-repair-gene-polymorphisms-to-gastric-cancer-risk-and-phenotype
#15
Patricia Carrera-Lasfuentes, Angel Lanas, Luis Bujanda, Mark Strunk, Enrique Quintero, Santos Santolaria, Rafael Benito, Federico Sopeña, Elena Piazuelo, Concha Thomson, Angeles Pérez-Aisa, David Nicolás-Pérez, Elizabeth Hijona, Jesús Espinel, Rafael Campo, Marisa Manzano, Fernando Geijo, María Pellise, Manuel Zaballa, Ferrán González-Huix, Jorge Espinós, Llúcia Titó, Luis Barranco, Mauro D'Amato, María Asunción García-González
Variations in DNA repair genes have been reported as key factors in gastric cancer (GC) susceptibility but results among studies are inconsistent. We aimed to assess the relevance of DNA repair gene polymorphisms and environmental factors to GC risk and phenotype in a Caucasian population in Spain. Genomic DNA from 603 patients with primary GC and 603 healthy controls was typed for 123 single nucleotide polymorphisms in DNA repair genes using the Illumina platform. Helicobacter pylori infection with CagA strains (odds ratio (OR): 1...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28408828/access-to-diagnosis-treatment-and-supportive-services-among-pharmacotherapy-treated-children-adolescents-with-adhd-in-europe-data-from-the-caregiver-perspective-on-pediatric-adhd-survey
#16
Moshe Fridman, Tobias Banaschewski, Vanja Sikirica, Javier Quintero, Kristina S Chen
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common childhood psychiatric disorders and negatively impacts caregivers' lives. Factors including barriers to accessing care, dissatisfaction with support services, and lack of caregiver resources may contribute to this. OBJECTIVES: To report caregivers' experiences of ADHD diagnosis, behavioral therapy (BT), and supportive care for children/adolescents with ADHD. METHODS: The Caregiver Perspective on Pediatric ADHD (CAPPA) survey included caregivers of children/adolescents (6-17 years) from ten European countries who were currently receiving/had received ADHD pharmacotherapy in the previous 6 months...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28406963/historical-and-ecological-drivers-of-the-spatial-pattern-of-chondrichthyes-species-richness-in-the-mediterranean-sea
#17
María José Meléndez, José Carlos Báez, José Miguel Serna-Quintero, Juan Antonio Camiñas, Ignacio de Loyola Fernández, Raimundo Real, David Macías
Chondrichthyes, which include Elasmobranchii (sharks and batoids) and Holocephali (chimaeras), are a relatively small group in the Mediterranean Sea (89 species) playing a key role in the ecosystems where they are found. At present, many species of this group are threatened as a result of anthropogenic effects, including fishing activity. Knowledge of the spatial distribution of these species is of great importance to understand their ecological role and for the efficient management of their populations, particularly if affected by fisheries...
2017: PloS One
https://www.readbyqxmd.com/read/28406493/genetic-characterization-and-influence-on-inflammatory-bowel-disease-expression-in-a-diverse-hispanic-south-florida-cohort
#18
Oriana M Damas, Lissette Gomez, Maria A Quintero, Evadnie Rampersaud, Susan Slifer, Gary W Beecham, David H Kerman, Amar R Deshpande, Daniel A Sussman, Maria T Abreu, Jacob L McCauley
OBJECTIVES: Hispanics represent an understudied inflammatory bowel disease (IBD) population. Prior studies examining genetic predisposition to IBD in Hispanics are limited. In this study, we examined whether European-derived IBD variants confer risk in Hispanics and their influence on IBD phenotype in Hispanics compared to non-Hispanic whites (NHW). METHODS: Self-identified Hispanics and NHWs with IBD were included. Hispanic controls were included for our genetic analyses...
April 13, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28403975/-fetoscopic-laser-coagulation-in-200%C3%A2-consecutive-monochorionic-pregnancies-with-twin-twin-transfusion-syndrome
#19
L Lecointre, N Sananès, A S Weingertner, A Gaudineau, C Akladios, V Cavillon, B Langer, R Favre
OBJECTIVES: To report preoperative data, surgical characteristics, complications and perinatal outcome of twin-twin transfusion syndrome (TTTS) managed with laser ablation surgery, to analyze predictors of neonatal survival and to compare the 100 most recent cases with the older 100. MATERIALS AND METHODS: Observational cohort moncentric study of 200 cases of TTTS consecutively treated with fetoscopic laser coagulation between January 2004 and December 2014...
February 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28396975/an-evaluation-of-molybdenum-toxicity-to-the-oligochaete-tubifex-tubifex-and-early-life-stages-of-brown-trout-salmo-trutta
#20
Brett T Lucas, Claudio Quinteros, Charlene Burnett-Seidel, James R Elphick
Limited data are available describing the aquatic toxicity of molybdenum in freshwater environments, making it difficult to assess the aquatic risk to freshwater organisms. In order to increase available information on the aquatic toxicity of molybdenum, a 96-h LC50 test with the oligochaete Tubifex tubifex and an 85-day development test using brown trout, Salmo trutta, were conducted. The T. tubifex test resulted in an LC50 value of 2782 mg/L. No adverse effects were observed on brown trout survival or length in the concentrations tested, however an IC10 value for growth (wet weight) was determined to be 202 mg/L...
June 2017: Bulletin of Environmental Contamination and Toxicology
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