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https://www.readbyqxmd.com/read/28745768/the-sos-chromotest-applied-for-screening-plant-antigenotoxic-agents-against-ultraviolet-radiation
#1
J L Fuentes, A García Forero, N Quintero Ruiz, C A Prada Medina, N Rey Castellanos, D A Franco Niño, D A Contreras García, Y Córdoba Campo, E E Stashenko
In this work, we investigated the usefulness of the SOS Chromotest for screening plant antigenotoxic agents against ultraviolet radiation (UV). Fifty Colombian plant extracts obtained by supercritical fluid (CO2) extraction, twelve plant extract constituents (apigenin, carvacrol, β-caryophyllene, 1,8-cineole, citral, p-cymene, geraniol, naringenin, pinocembrin, quercetin, squalene, and thymol) and five standard antioxidant and/or photoprotective agents (curcumin, epigallocatechin gallate, resveratrol, α-tocopherol, and Trolox®) were evaluated for their genotoxicity and antigenotoxicity against UV using the SOS Chromotest...
July 26, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28739644/nrt1-5-npf7-3-functions-as-a-proton-coupled-h-k-antiporter-for-k-loading-into-the-xylem-in-arabidopsis
#2
Hong Li, Miao Yu, Xin-Qiao Du, Zhi-Fang Wang, Wei-Hua Wu, Francisco J Quintero, Xue-Hua Jin, Hao-Dong Li, Yi Wang
Potassium and nitrogen are essential macronutrients for plant growth and have a positive impact on crop yield. Previous studies have indicated that the absorption and translocation of K+ and NO3- are correlated with each other in plants; however, the molecular mechanism that coordinates K+ and NO3- transport remains unknown. In this study, using a forward genetic approach, we isolated a low-K+-sensitive Arabidopsis mutant lks2 that showed a leaf-chlorosis phenotype under low-K+ conditions. LKS2 encodes the transporter NRT1...
July 24, 2017: Plant Cell
https://www.readbyqxmd.com/read/28738788/magnesium-sulfate-for-6-vs-24-hours-post-delivery-in-patients-who-received-magnesium-sulfate-for-less-than-8-hours-before-birth-a-randomized-clinical-trial
#3
Paulino Vigil-De Gracia, Ricardo Ramirez, Yarelys Durán, Arelis Quintero
BACKGROUND: To compare the benefits of magnesium sulfate for 24 h (h) postpartum versus 6 h postpartum in patients who received magnesium sulfate (Mg) for less than 8 h before birth. METHODS: A randomized, multicenter, open study was conducted between November 2013 and October 2016 in three teaching maternity hospitals in Panama. Pregnant women diagnosed with severe pre-eclampsia or pre-eclampsia with severe features at more than 20 weeks gestation were invited to participate...
July 24, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28728796/-lifetime-psychiatric-disorders-a-comparision-study-between-offspring-of-parents-with-bipolar-disorder-type-i-versus-the-offspring-of-community-controls-parents
#4
Juan David Palacio-Ortiz, Cristian Esteban Peña-Quintero, María Alejandra Gómez-Valero, Paula Andrea Bustamante-Gómez, Pilar Helena Arroyave-Sierra, Cristian David Vargas-Upeguí, Carlos López-Jaramillo
INTRODUCTION: Literature reports show that Bipolar Offspring (BO) present with a wide range of psychiatric disorders. Comparison between BO and Control Parent Offspring (CPO) may help to identify which psychopathological findings are specific to this high-risk group. OBJECTIVE: To compare the psychopathological characteristics between a group of BO type-I and a group of CPO, by identifying the presence of psychiatric disorders according the DSM-IV-TR. METHODS: A descriptive-correlational, cross-sectional and comparative study was conducted with 127 offspring of parents with bipolar disorder type-I from the multimodal intervention program (PRISMA) and with 150 CPO between 6 and 30 years of age...
July 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/28725107/retrospective-study-of-the-relationship-of-torque-teno-sus-virus-1a-and-torque-teno-sus-virus-1b-with-porcine-circovirus-associated-disease
#5
Alejandro Vargas-Ruiz, Hugo Ramírez-Álvarez, José I Sánchez-Betancourt, Víctor Quintero-Ramírez, Ignacio C Rangel-Rodríguez, Joel A Vázquez-Perez, Lucia A García-Camacho
Genus Iotatorquevirus consists of 2 species, Torque teno sus virus 1a and Torque teno sus virus 1b, which are ubiquitous in swine populations, and are widely reported in association with porcine circovirus associated disease (PCVAD). To evaluate the relationship with PCVAD, 100 formalin-fixed paraffin-embedded tissue samples were used to detect both Iotatorquevirus species by nested PCR and sequencing. Sixty-eight PCVAD cases were selected as well as 32 porcine circovirus type 2 (PCV2) non-affected cases. Overall, 33 of the 100 cases were positive for Torque teno sus virus 1a and 8 of 100 were positive for Torque teno sus virus 1b...
July 2017: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/28720011/facial-emotion-recognition-and-empathy-in-employees-at-a-juvenile-detention-center
#6
Luz Anyela Morales Quintero, Jairo Muñoz-Delgado, José Carlos Sánchez-Ferrer, Ana Fresán, Martin Brüne, Iván Arango de Montis
Numerous studies have shown that emotion recognition is impaired in individuals with a history of violent offenses, especially in those diagnosed with psychopathy. However, in criminological contexts, there is insufficient research regarding the role of empathy and facial emotion recognition abilities of personnel employed in correction centers. Accordingly, we sought to explore facial emotion recognition abilities and empathy in administrative officers and security guards at a center for institutionalized juvenile offenders...
July 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28717206/an-amino-acid-signature-associated-with-obesity-predicts-2-year-risk-of-hypertriglyceridemia-in-school-age-children
#7
Sofia Moran-Ramos, Elvira Ocampo-Medina, Ruth Gutierrez-Aguilar, Luis Macías-Kauffer, Hugo Villamil-Ramírez, Blanca E López-Contreras, Paola León-Mimila, Joel Vega-Badillo, Roxana Gutierrez-Vidal, Ricardo Villarruel-Vazquez, Erandi Serrano-Carbajal, Blanca E Del-Río-Navarro, Adriana Huertas-Vázquez, Teresa Villarreal-Molina, Isabel Ibarra-Gonzalez, Marcela Vela-Amieva, Carlos A Aguilar-Salinas, Samuel Canizales-Quinteros
Childhood obesity is associated with a number of metabolic abnormalities leading to increased cardiovascular risk. Metabolites can be useful as early biomarkers and new targets to promote early intervention beginning in school age. Thus, we aimed to identify metabolomic profiles associated with obesity and obesity-related metabolic traits. We used data from the Obesity Research Study for Mexican children (ORSMEC) in Mexico City and included a case control (n = 1120), cross-sectional (n = 554) and a longitudinal study (n = 301) of 6-12-year-old children...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28716817/pi3k-gamma-delta-and-notch1-cross-regulate-pathways-that-define-the-t-cell-acute-lymphoblastic-leukemia-disease-signature
#8
Evgeni Efimenko, Utpal P Davé, Irina V Lebedeva, Yao Shen, Maria J Sanchez-Quintero, Daniel Diolaiti, Andrew Kung, Brian J Lannutti, Jianchung Chen, Ronald Realubit, Zoya Niatsetskiya, Vadim Ten, Charles Karan, Xi Chen, Andrea Califano, Thomas G Diacovo
PI3K/AKT and NOTCH1 signaling pathways are frequently dysregulated in T-cell acute lymphoblastic leukemias (T-ALL). Although we have shown that the combined activities of the class I PI3K isoforms p110γ and p110δ play a major role in the development and progression of PTEN null T-ALL, it has yet to be determined whether their contribution to leukemogenic programing is unique from that associated with NOTCH1 activation. Using a Lmo2-driven mouse model of T-ALL in which both the PI3K/AKT and NOTCH1 pathways are aberrantly upregulated, we now demonstrate that the combined activities of PI3Kγ/δ have both overlapping and distinct roles from NOTCH1 in generating T-ALL disease signature and in promoting tumor cell growth...
July 17, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28716280/association-of-polymorphisms-and-reduced-expression-levels-of-the-nr4a2-gene-with-parkinson-s-disease-in-a-mexican-population
#9
Elizabeth Ruiz-Sánchez, Petra Yescas, Mayela Rodríguez-Violante, Nancy Martínez-Rodríguez, Jesica N Díaz-López, Adriana Ochoa, Sergio S Valdes-Rojas, Daniel Magos-Rodríguez, Julio C Rojas-Castañeda, Amin Cervantes-Arriaga, Samuel Canizales-Quinteros, Patricia Rojas
INTRODUCTION: The NR4A2 transcription factor is important in the development, survival and phenotype of dopaminergic neurons and it is postulated as a possible biomarker for Parkinson's disease (PD). Therefore, our aim was to analyze in a sample of a Mexican population with idiopathic PD, mutations (in two hotspot mutation regions) and two polymorphisms (rs34884856 in promotor and rs35479735 intronic regions) of the NR4A2 gene. We also evaluate the levels of NR4A2 gene expression in peripheral blood for a Mexican population, and identify whether they are associated with NR4A2 gene polymorphisms...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28714892/passive-downhole-pressure-sensor-based-on-surface-acoustic-wave-technology
#10
Sully M M Quintero, Sávio W O Figueiredo, Victor L Takahashi, Roberth A W Llerena, Arthur M B Braga
A passive surface acoustic wave (SAW) pressure sensor was developed for real-time pressure monitoring in downhole application. The passive pressure sensor consists of a SAW resonator, which is attached to a circular metal diaphragm used as a pressure transducer. While the membrane deflects as a function of pressure applied, the frequency response changes due to the variation of the SAW propagation parameters. The sensitivity and linearity of the SAW pressure sensor were measured to be 8.3 kHz/bar and 0.999, respectively...
July 15, 2017: Sensors
https://www.readbyqxmd.com/read/28699100/reward-devaluation-disrupts-latent-inhibition-in-fear-conditioning
#11
Luís Gonzalo De la Casa, Auxiliadora Mena, Juán Carlos Ruiz-Salas, Esperanza Quintero, Mauricio R Papini
Three experiments explored the link between reward shifts and latent inhibition (LI). Using consummatory procedures, rewards were either downshifted from 32% to 4% sucrose (Experiments 1-2), or upshifted from 4% to 32% sucrose (Experiment 3). In both cases, appropriate unshifted controls were also included. LI was implemented in terms of fear conditioning involving a single tone-shock pairing after extensive tone-only preexposure. Nonpreexposed controls were also included. Experiment 1 demonstrated a typical LI effect (i...
July 11, 2017: Learning & Behavior
https://www.readbyqxmd.com/read/28694197/feasibility-safety-and-utility-of-advanced-critical-care-transesophageal-echocardiography-performed-by-pulmonary-critical-care-fellows-in-a-medical-icu
#12
Yunuen Aguilera Garcia, Luis Quintero, Karan Singh, Viera Lakticova, AnnaMaria Iakovou, Seth Koenig, Mangala Narasimhan, Paul H Mayo
BACKGROUND: Competence in advanced critical care transesophageal echocardiography allows the intensivist to diagnose and manage cardiopulmonary failure when transthoracic echocardiography is not sufficient to answer the clinical question. This report describes the feasibility, safety, and utility of transesophageal echocardiography performed by pulmonary and critical care fellows in a medical ICU in critically ill patients who were mechanically ventilated. METHODS: This longitudinal descriptive study of advanced transesophageal echocardiography was performed in patients who were mechanically ventilated...
July 8, 2017: Chest
https://www.readbyqxmd.com/read/28692751/multilevel-covariance-regression-with-correlated-random-effects-in-the-mean-and-variance-structure
#13
Adrian Quintero, Emmanuel Lesaffre
Multivariate regression methods generally assume a constant covariance matrix for the observations. In case a heteroscedastic model is needed, the parametric and nonparametric covariance regression approaches can be restrictive in the literature. We propose a multilevel regression model for the mean and covariance structure, including random intercepts in both components and allowing for correlation between them. The implied conditional covariance function can be different across clusters as a result of the random effect in the variance structure...
July 10, 2017: Biometrical Journal. Biometrische Zeitschrift
https://www.readbyqxmd.com/read/28688048/susceptibility-background-for-type-2-diabetes-in-eleven-mexican-indigenous-populations-hnf4a-gene-analysis
#14
M A Granados-Silvestre, M G Ortiz-López, J Granados, S Canizales-Quinteros, Rosenda I Peñaloza-Espinosa, C Lechuga, V Acuña-Alonzo, K Sánchez-Pozos, M Menjivar
The genetic risk of developing type 2 diabetes (T2D) increases in parallel with the proportion of Native American ancestry. Mestizo Mexicans have a 70% Native Amerindian genetic background. The T130I polymorphism in the HNF4A gene has been associated with early-onset T2D in mestizo Mexicans. Thus, the aim of the present study was to evaluate the frequency and relationship of the T130I variant in the HNF4A gene with risk factors for developing T2D in eleven indigenous groups from Mexico. In two groups, all exons of the HNF4A gene were directly sequenced; in the remaining the T130I polymorphism was analyzed by restriction fragment length polymorphism...
July 7, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28687765/reduction-of-epileptiform-activity-in-ketogenic-mice-the-role-of-monocarboxylate-transporters
#15
Linda S Forero-Quintero, Joachim W Deitmer, Holger M Becker
Epilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide. Ketogenic diet (KD) can be a very effective treatment for intractable epilepsy. Potential mechanisms of action for KD have been proposed, including the re-balance among excitatory and inhibitory neurotransmission and decrease in the glycolytic rate in brain cells. KD has been shown to have an effect on the expression pattern of monocarboxylate transporters (MCT), however, it is unknown whether MCT transport activity is affected by KD and linked to the reduction of seizures during KD...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28682969/early-colonoscopy-improves-the-outcome-of-patients-with-symptomatic-colorectal-cancer
#16
Inmaculada Alonso-Abreu, Onofre Alarcón-Fernández, Antonio Z Gimeno-García, Rafael Romero-García, Marta Carrillo-Palau, David Nicolás-Pérez, Alejandro Jiménez, Enrique Quintero
BACKGROUND: Long waiting times from early symptoms to diagnosis and treatment may influence the staging and prognosis of patients with colorectal cancer. We analyzed the effect of colonoscopy timing on the outcome of these patients. OBJECTIVE: This study aimed to compare the outcome (tumoral staging and long-term survival) of patients with suspected colorectal cancer according to diagnostic colonoscopy timing. DESIGN: This study is an analysis of a prospectively maintained database...
August 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28681843/ballistic-superconductivity-in-semiconductor-nanowires
#17
Hao Zhang, Önder Gül, Sonia Conesa-Boj, Michał P Nowak, Michael Wimmer, Kun Zuo, Vincent Mourik, Folkert K de Vries, Jasper van Veen, Michiel W A de Moor, Jouri D S Bommer, David J van Woerkom, Diana Car, Sébastien R Plissard, Erik P A M Bakkers, Marina Quintero-Pérez, Maja C Cassidy, Sebastian Koelling, Srijit Goswami, Kenji Watanabe, Takashi Taniguchi, Leo P Kouwenhoven
Semiconductor nanowires have opened new research avenues in quantum transport owing to their confined geometry and electrostatic tunability. They have offered an exceptional testbed for superconductivity, leading to the realization of hybrid systems combining the macroscopic quantum properties of superconductors with the possibility to control charges down to a single electron. These advances brought semiconductor nanowires to the forefront of efforts to realize topological superconductivity and Majorana modes...
July 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/28680177/redesign-of-the-clinical-pharmacy-practice-model-in-a-tertiary-academic-hospital-in-medell%C3%A3-n-colombia
#18
Juan Pablo Botero Aguirre, Andrés Felipe Valencia Quintero, Elkyn Johan Granados Vega
No abstract text is available yet for this article.
May 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28676763/sleep-deprivation-in-young-and-healthy-subjects-is-more-sensitively-identified-by-higher-frequencies-of-electrodermal-activity-than-by-skin-conductance-level-evaluated-in-the-time-domain
#19
Hugo F Posada-Quintero, Jeffrey B Bolkhovsky, Natasa Reljin, Ki H Chon
We analyzed multiple measures of the autonomic nervous system (ANS) based on electrodermal activity (EDA) and heart rate variability (HRV) for young healthy subjects undergoing 24-h sleep deprivation. In this study, we have utilized the error awareness test (EAT) every 2 h (13 runs total), to evaluate the deterioration of performance. EAT consists of trials where the subject is presented words representing colors. Subjects are instructed to press a button ("Go" trials) or withhold the response if the word presented and the color of the word mismatch ("Stroop No-Go" trial), or the screen is repeated ("Repeat No-Go" trials)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28671721/chloride-passivation-of-zno-electrodes-improves-charge-extraction-in-colloidal-quantum-dot-photovoltaics
#20
Jongmin Choi, Younghoon Kim, Jea Woong Jo, Junghwan Kim, Bin Sun, Grant Walters, F Pelayo García de Arquer, Rafael Quintero-Bermudez, Yiying Li, Chih Shan Tan, Li Na Quan, Andrew Pak Tao Kam, Sjoerd Hoogland, Zhenghong Lu, Oleksandr Voznyy, Edward H Sargent
The tunable bandgap of colloidal quantum dots (CQDs) makes them an attractive material for photovoltaics (PV). The best present-day CQD PV devices employ zinc oxide (ZnO) as an electron transport layer; however, it is found herein that ZnO's surface defect sites and unfavorable electrical band alignment prevent devices from realizing their full potential. Here, chloride (Cl)-passivated ZnO generated from a solution of presynthesized ZnO nanoparticles treated using an organic-solvent-soluble Cl salt is reported...
July 3, 2017: Advanced Materials
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