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transcutaneous tibial nerve stimulation

Peter L Lu, Carlo Di Lorenzo
PURPOSE OF REVIEW: The use of neurostimulation for treatment of gastrointestinal disorders has been growing over the past two to three decades. Our objective is to review current applications of neurostimulation in the treatment of gastrointestinal disorders with an emphasis on the use of these treatment modalities in children. RECENT FINDINGS: Gastric electrical stimulation can lead to symptomatic improvement in children with chronic nausea and vomiting refractory to conventional treatment, and a recent report of long-term outcomes is encouraging...
October 2016: Current Opinion in Pediatrics
Anne J Wright, Mirna Haddad
Both non-invasive and invasive electroneurostimulation (ENS) modalities for bladder bowel dysfunction have been studied and reported in children. A summary of the proposed mechanism of actions and the more commonly used and recently reported techniques and outcomes are described. This includes transcutaneous electrical nerve stimulation, functional electrical nerve stimulation, intravesical electrical nerve stimulation, percutaneous tibial nerve stimulation and sacral neuromodulation in conditions including overactive bladder, enuresis, dysfunctional voiding, constipation, combined bladder bowel dysfunction and neuropathic bladder and bowel dysfunction...
May 27, 2016: European Journal of Paediatric Neurology: EJPN
Adélia Lúcio, Carlos Arturo Levi Dʼancona, Maria Carolina Perissinotto, Linda McLean, Benito Pereira Damasceno, Maria Helena Baena de Moraes Lopes
PURPOSE: The aim of this study was to evaluate the effect of intravaginal neuromuscular electrical stimulation (NMES) and transcutaneous tibial nerve stimulation (TTNS) on lower urinary tract symptoms (LUTS) and health-related quality of life in women undergoing pelvic floor muscle (PFM) training (PFMT) with multiple sclerosis (MS) and to compare the efficacy of these 2 approaches. DESIGN: Randomized controlled trial. METHODS: Thirty women with MS and LUTS were randomly allocated to 1 of 3 groups and received treatment for 12 weeks...
July 2016: Journal of Wound, Ostomy, and Continence Nursing
Valentín Manríquez, Rodrigo Guzmán, Michel Naser, Amalia Aguilera, Simonie Narvaez, Ariel Castro, Steven Swift, G Alessandro Digesu
INTRODUCTION AND HYPOTHESIS: The aim of this study was to evaluate the effectiveness of transcutaneous posterior tibial nerve stimulation (T.C. PTNS) versus extended release oxybutynin (E.R.O.) in patients with overactive bladder. MATERIALS AND METHODS: Seventy female patients were randomized to receive either 10mg E.R.O. daily or T.C. PTNS, using a TENS machine program with the 20Hz, 200 cycles/s, and normal stimulation setting for two 30-min sessions, each week for a 12-week period...
January 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Emma J Horrocks, Stephen A Bremner, Natasha Stevens, Christine Norton, Deborah Gilbert, P Ronan O'Connell, Sandra Eldridge, Charles H Knowles
BACKGROUND: Faecal incontinence (FI) is a common condition which is often under-reported. It is distressing for those suffering from it, impacting heavily on their quality of life. When conservative strategies fail, treatment options are limited. Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive outpatient treatment, shown in preliminary case series to have significant effectiveness; however, no randomised controlled trial has been conducted. OBJECTIVES: To assess the effectiveness of PTNS compared with sham electrical stimulation in the treatment of patients with FI in whom initial conservative strategies have failed...
September 2015: Health Technology Assessment: HTA
Anette Schrag, Anna Sauerbier, Kallol Ray Chaudhuri
Nonmotor manifestations in Parkinson's disease (PD) encompass a range of clinical features, including neuropsychiatric problems, autonomic dysfunction, sleep disorders, fatigue, and pain. Despite their importance for patients' quality of life, the evidence base for their treatment is relatively sparse. Nevertheless, the last few years have seen a number of new trials starting that specifically address nonmotor features as an outcome measure in clinical trials. Large randomized, controlled trials in the last 3 years reported improvement of psychosis with the new selective serotonin 5-HT2A inverse agonist pimavanserin and of postural hypotension with the oral norepinephrine precursor droxidopa...
September 15, 2015: Movement Disorders: Official Journal of the Movement Disorder Society
Zhaocun Zhang, Richard C Slater, Matthew C Ferroni, Brian T Kadow, Timothy D Lyon, Bing Shen, Zhiying Xiao, Jicheng Wang, Audry Kang, James R Roppolo, William C de Groat, Changfeng Tai
In α-chloralose anesthetized cats, we examined the role of opioid receptor (OR) subtypes (µ, κ, and δ) in tibial nerve stimulation (TNS)-induced inhibition of bladder overactivity elicited by intravesical infusion of 0.25% acetic acid (AA). The sensitivity of TNS inhibition to cumulative i.v. doses of selective OR antagonists (cyprodime for µ, nor-binaltorphimine for κ, or naltrindole for δ ORs) was tested. Naloxone (1 mg/kg, i.v., an antagonist for µ, κ, and δ ORs) was administered at the end of each experiment...
November 2015: Journal of Pharmacology and Experimental Therapeutics
Craig J Rimmer, Charles H Knowles, Michael Lamparelli, Paul Durdey, Ian Lindsey, Louise Hunt, Karen Nugent, Kathryn A Gill
BACKGROUND: Fecal incontinence is a socially disabling condition that affects ≤15% of adults. Neuromodulatory treatments for fecal incontinence are now well established. Less invasive, cheaper, and more ambulatory forms of neuromodulation are under exploration. OBJECTIVE: The purpose of this study was to assess the acceptability and safety of a new ambulatory tibial nerve stimulation device and to determine clinical effect size for 2 differing regimens of therapy...
October 2015: Diseases of the Colon and Rectum
F Iqbal, B Collins, G P Thomas, A Askari, E Tan, R J Nicholls, C J Vaizey
AIM: Chronic constipation is difficult to treat when symptoms are intractable. Colonic propulsion may be altered by distal neuromodulation but this is conventionally delivered percutaneously. Transcutaneous tibial nerve stimulation is noninvasive and cheap: this study aimed to assess its efficacy in chronic constipation. METHOD: Eighteen patients (median age 46 years, 12 female) with chronic constipation were recruited consecutively. Conservative and behavioural therapy had failed to improve symptoms in all 18...
February 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Tamer Youssef, Mohamed Youssef, Waleed Thabet, Ahmed Lotfy, Reham Shaat, Eman Abd-Elrazek, Mohamed Farid
OBJECTIVES: The objective of this study was to evaluate the efficacy of transcutaneous electrical posterior tibial nerve stimulation in treatment of patients with chronic anal fissure and to compare it with the conventional lateral internal sphincterotomy. PATIENTS AND METHODS: Consecutive patients with chronic anal fissure were randomly allocated into two treatment groups: transcutaneous electrical posterior tibial nerve stimulation group and lateral internal sphincterotomy group...
October 2015: International Journal of Surgery
Steven D Wexner
No abstract text is available yet for this article.
October 24, 2015: Lancet
Charles H Knowles, Emma J Horrocks, Stephen A Bremner, Natasha Stevens, Christine Norton, P Ronan O'Connell, Sandra Eldridge
BACKGROUND: Percutaneous tibial nerve stimulation (PTNS) is a new ambulatory therapy for faecal incontinence. Data from case series suggest it has beneficial outcomes in 50-80% patients; however its effectiveness against sham electrical stimulation has not been investigated. We therefore aimed to assess the short-term efficacy of PTNS against sham electrical stimulation in adults with faecal incontinence. METHODS: We did a double-blind, multicentre, pragmatic, parallel-group, randomised controlled trial (CONtrol of Faecal Incontinence using Distal NeuromodulaTion [CONFIDeNT]) in 17 specialist hospital units in the UK that had the skills to manage patients with faecal incontinence...
October 24, 2015: Lancet
Nitesh Patidar, Varun Mittal, Manoj Kumar, Sanjoy Kumar Sureka, Sohrab Arora, Mohd Sualeh Ansari
BACKGROUND: Non-neurogenic overactive bladder (OAB) is a common problem in children that may affect their quality of life. Various methods of neuromodulation have been reported to treat refractory lower urinary tract dysfunction. Since most of these techniques are invasive, they are less applicable in children. OBJECTIVE: To evaluate the efficacy of transcutaneous PTNS in treatment of OAB in children, in a randomized clinical setting. STUDY DESIGN: This study was single-blinded, prospective, sham controlled randomized trial...
December 2015: Journal of Pediatric Urology
Maged M Ragab, Ahmad M Tawfik, Mohamed Abo El-enen, Mohamed Elnady, Osama M El-Gamal, Mohamed El-Kordy, Tarek Gameel, Mohamed Rasheed
OBJECTIVE: To evaluate the efficacy of intermittent percutaneous tibial nerve stimulation (PTNS) as a treatment modality for patients with refractory interstitial cystitis/bladder pain syndrome (IC/BPS). PATIENTS AND METHODS: Twenty female patients with IC/BPS (mean symptom duration of 4.5 ± 2.4 years) each had a 30-minute session of PTNS per week for 12 successive weeks and the symptoms were assessed before, during, and after the treatment sessions by voiding diary, visual analog scale (VAS) for pain, interstitial cystitis symptom and problem indices (ICSI and ICPI), and global response assessment (GRA) scale...
October 2015: Urology
Oliver Preyer, Wolfgang Umek, Thomas Laml, Vesna Bjelic-Radisic, Boris Gabriel, Martina Mittlboeck, Engelbert Hanzal
OBJECTIVE: We performed a randomised controlled trial of percutaneous tibial nerve stimulation (PTNS) versus tolterodine for treating treatment naïve women with overactive bladder (OAB). STUDY DESIGN: 36 patients with symptoms of OAB were randomised to 3 months of treatment with weekly PTNS or tolterodine (2mg bid p.o.). The primary outcome measure was the difference of micturitions per 24h. The secondary outcome measure was the impact on quality of life (QoL) measured with a visual analogue scale (VAS) between baseline and after 3 months of therapy...
August 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
O Bouali, L Even, S Mouttalib, J Moscovici, P Galinier, X Game
INTRODUCTION: The purpose of this study was to evaluate safety and tolerability of transcutaneous tibial nerve stimulation (TENS) in patients under 15years of age with refractory overactive bladder. MATERIALS AND METHODS: A retrospective analysis was conducted on outcomes of TENS (1daily 20-minute session, 10Hz) in patients with refractory overactive bladder, excluding patients with neurogenic bladder. Treatment efficacy was evaluated on symptomatic improvement and voiding schedule...
September 2015: Progrès en Urologie
Nadia Boudaoud, Aurélien Binet, Antoine Line, Dalila Chaouadi, Catherine Jolly, Caroline Francois Fiquet, Thomas Ripert, Marie Laurence Poli Merol
OBJECTIVE: To assess the objective efficacy of transcutaneous posterior tibial nerve stimulation in children presenting with overactive bladder resistant to well conducted treatment. MATERIAL AND METHOD: This was a randomized, double-blind, controlled study on 20 children with OAB. All patients were previously treated with anticholinergic drugs associated with detrusor rehabilitation, diet advice, bladder-voiding hygiene and constipation treatment, with poor clinical results...
June 2015: Journal of Pediatric Urology
Autumn L Edenfield, Cindy L Amundsen, Jennifer M Wu, Pamela J Levin, Nazema Y Siddiqui
IMPORTANCE AND OBJECTIVES: Posterior tibial nerve stimulation (PTNS) is a potential emerging therapy for fecal incontinence (FI). The aim of this study was to systematically review the literature regarding the efficacy of PTNS as a treatment of FI. EVIDENCE ACQUISITION: We searched MEDLINE/PubMed, EMBASE, and Cochrane databases from inception through November 2013. We included English-language full-text articles reporting outcomes for FI with either percutaneous PTNS or transcutaneous techniques (transcutaneous electrical nerve stimulation)...
May 2015: Obstetrical & Gynecological Survey
Jean-François Lecompte, Geraldine Hery, Jean-Michel Guys, Claude Louis-Borrione
OBJECTIVE: To examine the effectiveness of posterior tibial nerve stimulation (PTNS) for the treatment of fecal and urinary incontinence in children with malformations of the bowel or neurological pathologies. INTRODUCTION: Treatment of fecal and urinary leaks, in cases of congenital malformations remains a challenge. Recent studies in adults have shown the effectiveness of PTNS. METHOD: Eight children: 4 with anorectal malformations, 3 with neurological causes (1 medullary lipoma, 1 Arnold Chiari malformation, 1 sacrococcygeal teratoma) and 1 with Hirschsprung's disease presenting with serious anal incontinence, despite extensive bowel management during at least 2 years, were treated with PTNS...
April 2015: Journal of Pediatric Surgery
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