keyword
MENU ▼
Read by QxMD icon Read
search

Glomerular filtration rate

keyword
https://www.readbyqxmd.com/read/28922687/comparison-of-perioperative-renal-and-oncologic-outcomes-in-robotic-assisted-versus-open-partial-nephrectomy
#1
Jo-Lynn Tan, Mark Frydenberg, Jeremy Grummet, Uri Hanegbi, Ross Snow, Sarah Mann, Kirobel Begashaw, Daniel Moon
BACKGROUND: To compare perioperative, renal and oncological outcomes after robotic-assisted partial nephrectomy (RAPN) versus open partial nephrectomy (OPN) for the treatment of renal tumours. METHODS: All partial nephrectomies performed at a Metropolitan Urology Centre between 2010 and 2016 were analysed. Baseline data was collected for patient demographics, tumour characteristics (tumour size, laterality and polarity, RENAL scores), and perioperative variables (e...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28921875/chronic-kidney-disease-and-incident-apparent-treatment-resistant-hypertension-among-blacks-data-from-the-jackson-heart-study
#2
Rikki M Tanner, Daichi Shimbo, Marguerite R Irvin, Tanya M Spruill, Samantha G Bromfield, Samantha R Seals, Bessie A Young, Paul Muntner
It is unclear whether black patients with chronic kidney disease (CKD) vs those without CKD who take antihypertensive medication have an increased risk for apparent treatment-resistant hypertension (aTRH). The authors analyzed 1741 Jackson Heart Study participants without aTRH taking antihypertensive medication at baseline. aTRH was defined as uncontrolled blood pressure while taking three antihypertensive medication classes or taking four or more antihypertensive medication classes, regardless of blood pressure level...
September 17, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28921862/efficacy-and-safety-of-the-addition-of-ertugliflozin-in-patients-with-type-2-diabetes-mellitus-inadequately-controlled-with-metformin-and-sitagliptin-the-vertis-sita2-placebo-controlled-randomized-study
#3
Samuel Dagogo-Jack, Jie Liu, Roy Eldor, Guillermo Amorin, Jeremy Johnson, Darcy Hille, Yuqin Liao, Susan Huyck, Gregory Golm, Steven G Terra, James P Mancuso, Samuel S Engel, Brett Lauring
AIMS: To assess ertugliflozin in patients with type 2 diabetes inadequately controlled on metformin and sitagliptin. MATERIALS AND METHODS: In this double-blind randomized study (NCT02036515), patients (glycated haemoglobin [HbA1c] 7.0-10.5% [53-91 mmol/mol] on metformin ≥1500 mg/day and sitagliptin 100 mg/day; estimated glomerular filtration rate [eGFR] ≥60 mL/min/1.73 m(2) ) were randomized to ertugliflozin 5 mg once-daily, 15 mg once-daily, or placebo. Primary efficacy endpoint was change from baseline in HbA1c at Week 26; treatment was continued until Week 52...
September 17, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28920703/prognostic-usefulness-of-an-age-adapted-equation-for-renal-function-assessment-in-older-patients-with-acute-coronary-syndrome
#4
Lucía Rioboo Lestón, Emad Abu-Assi, Sergio Raposeiras-Roubin, Rafael Cobas-Paz, Berenice Caneiro-Queija, Jose Manuel Rodríguez-Rodríguez, Andres Íñiguez-Romo
BACKGROUND: Renal dysfunction negatively impacts survival in acute coronary syndrome patients. The Berlin Initiative Study creatinine-based (BIScrea) equation has recently been proposed for renal function assessment in older persons. However, up to now it is unknown if the superiority of the new BIScrea equation, with respect to the most recommended chronic kidney disease epidemiology collaboration creatinine-based (CKD-EPIcrea) formula, would translate into better risk prediction of adverse events in older patients with acute coronary syndrome...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28920466/annals-express-evaluation-of-common-paediatric-creatinine-based-glomerular-filtration-rate-gfr-estimating-equations-in-black-african-children-in-kwazulu-natal-south-africa
#5
Yashna Rampursat, Rajendra Bhimma, Elaene Naicker, Fozy Peer, Verena Gounden
Background The use of serum creatinine (S-Cr) equations for estimating glomerular filtration rate (GFR) is well known in adults and children. We evaluated the revised Schwartz creatinine based estimated GFR (eGFR) prediction equation in Black African children in KwaZulu-Natal, South Africa. Methods Review of medical records of all Black African patients aged 2-18 years old who have had GFR determined by intravenous Technetium-99m-diethylene-triamine-pentaacetate((9)(9)(m)Tc DTPA), for the period 1 January 2010 to 31 December 2014 at the Inkosi Albert Luthuli Central Hospital (IALCH), Durban, South Africa was performed...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28920100/a-urinary-fragment-of-mucin-1-subunit-%C3%AE-is-a-novel-biomarker-associated-with-renal-dysfunction-in-the-general-population
#6
Zhen-Yu Zhang, Susana Ravassa, Martin Pejchinovski, Wen-Yi Yang, Petra Zürbig, Begoña López, Fang-Fei Wei, Lutgarde Thijs, Lotte Jacobs, Arantxa González, Jens-Uwe Voigt, Peter Verhamme, Tatiana Kuznetsova, Javier Díez, Harald Mischak, Jan A Staessen
INTRODUCTION: Sequencing peptides included in the urinary proteome identifies the parent proteins and may reveal mechanisms underlying the pathophysiology of chronic kidney disease. METHODS: In 805 randomly recruited Flemish individuals (50.8% women; mean age, 51.1 years), we determined the estimated glomerular filtration rate (eGFR) from serum creatinine using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. We categorized eGFR according to the National Kidney Foundation Kidney Disease Outcomes Quality Initiative guideline...
September 2017: KI Reports
https://www.readbyqxmd.com/read/28918836/role-of-microalbuminuria-in-predicting-cardiovascular-mortality-in-individuals-with-subclinical-hypothyroidism
#7
Tushar A Tuliani, Maithili Shenoy, Kevin Belgrave, Abhishek Deshmukh, Sadip Pant, Anthony Hilliard, Luis Afonso
PURPOSE: Studies suggest that subclinical hypothyroidism (SCH) is related to cardiovascular mortality (CVM). We explored the role of microalbuminuria (MIA) as a predictor of long-term CVM in population with and without SCH with normal kidney function. MATERIALS AND METHODS: We examined the National Health and Nutrition Education Survey - III database (n = 6,812). Individuals younger than 40 years, thyroid-stimulating hormone levels ≥20 and ≤0.35mIU/L, estimated glomerular filtration rate <60mL/minute/1...
September 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28918487/clinical-risk-stratification-of-paediatric-renal-transplant-recipients-using-c1q-and-c3d-fixing-of-de-novo-donor-specific-antibodies
#8
Jon Jin Kim, Olivia Shaw, Chloe Martin, George Michaelides, Ramnath Balasubramaniam, Neil J Sebire, Nizam Mamode, Anthony Dorling, Robert Vaughan, Stephen D Marks
INTRODUCTION: We have previously shown that children who developed de novo donor-specific human leukocyte antigen (HLA) antibodies (DSA) had greater decline in allograft function. We hypothesised that patients with complement-activating DSA would have poorer renal allograft outcomes. METHODS: A total of 75 children developed DSA in the original study. The first positive DSA sample was subsequently tested for C1q and C3d fixing. The primary event was defined as 50% reduction from baseline estimated glomerular filtration rate and was analysed using the Kaplan-Meier estimator...
September 16, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28917713/the-bvas-is-an-independent-predictor-of-cardiovascular-events-and-cardiovascular-disease-related-mortality-in-patients-with-anca-associated-vasculitis-a-study-of-504-cases-in-a-single-chinese-center
#9
Yi-Hua Bai, Zhi-Ying Li, Dong-Yuan Chang, Min Chen, Cees G M Kallenberg, Ming-Hui Zhao
BACKGROUND: Cardiovascular diseases (CVD) are the major causes of death in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) during long-term follow-up. This study investigated risk factors for cardiovascular events (CVE) and CVD-related mortality in Chinese AAV patients. METHODS: Five hundred and four AAV patients in our center were retrospectively included. The predictive value of variables associated with CVE and CVD-related mortality were analyzed...
August 31, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28917602/comparing-inpatient-versus-outpatient-bowel-preparation-in-children-and-adolescents-undergoing-appendicovesicostomy
#10
David L Weatherly, Konrad M Szymanski, Benjamin M Whittam, William E Bennett, Shelly King, Rosalia Misseri, Martin Kaefer, Richard C Rink, Mark P Cain
PURPOSE: The need for mechanical inpatient bowel preparation (IBP) in reconstructive pediatric urology has come under scrutiny, secondary to literature demonstrating little benefit regarding outcomes. Starting in 2013, a majority of patients undergoing reconstructive procedures at our institution no longer underwent IBP. We hypothesized that outpatient bowel preparation (OBP) would reduce length of stay (LOS) without increasing postoperative complications after appendicovesicostomy surgery...
August 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28917208/prenatal-exposure-to-perfluoroalkyl-substances-and-birth-outcomes-in-a-spanish-birth-cohort
#11
Cyntia B Manzano-Salgado, Maribel Casas, Maria-Jose Lopez-Espinosa, Ferran Ballester, Carmen Iñiguez, David Martinez, Olga Costa, Loreto Santa-Marina, Eva Pereda-Pereda, Thomas Schettgen, Jordi Sunyer, Martine Vrijheid
BACKGROUND: Prenatal perfluorooctanoate (PFOA) exposure has been associated with reduced birth weight but maternal glomerular filtration rate (GFR) may attenuate this association. Further, this association remains unclear for other perfluoroalkyl substances (PFAS), such as perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), and perfluorononanoate (PFNA). We estimated associations between prenatal PFAS exposure and birth outcomes, and the influence of GFR, in a Spanish birth cohort...
September 13, 2017: Environment International
https://www.readbyqxmd.com/read/28916770/changes-in-cd73-cd39-and-cd26-expression-on-t-lymphocytes-of-anca-associated-vasculitis-patients-suggest-impairment-in-adenosine-generation-and-turn-over
#12
Lovis Kling, Urs Benck, Annette Breedijk, Lisa Leikeim, Marianne Heitzmann, Stefan Porubsky, Bernhard K Krämer, Benito A Yard, Anna-Isabelle Kälsch
Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes to T-cell differentiation and function. Adenosine concentrations are furthermore influenced by adenosine deaminase binding protein CD26. Because aberrant T-cell phenotypes had been reported in anti-neutrophil cytoplasmic auto-antibody (ANCA)-associated vasculitis (AAV) patients, an impaired expression of these molecules on T-cells of AAV patients was hypothesized in the present study. While in AAV patients (n = 29) CD26 was increased on CD4(+) lymphocytes, CD39 and CD73 were generally reduced on patients' T-cells...
September 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28916603/phase-2a-clinical-trial-of-mitochondrial-protection-elamipretide-during-stent-revascularization-in-patients-with-atherosclerotic-renal-artery-stenosis
#13
Ahmed Saad, Sandra M S Herrmann, Alfonso Eirin, Christopher M Ferguson, James F Glockner, Haraldur Bjarnason, Michael A McKusick, Sanjay Misra, Lilach O Lerman, Stephen C Textor
BACKGROUND: Atherosclerotic renal artery stenosis reduces renal blood flow (RBF) and amplifies stenotic kidney hypoxia. Revascularization with percutaneous transluminal renal angioplasty (PTRA) and stenting often fails to recover renal function, possibly because of ischemia/reperfusion injury developing after PTRA. Elamipretide is a mitochondrial-targeted peptide that binds to cardiolipin and stabilizes mitochondrial function. We tested the hypothesis that elamipretide plus PTRA would improve renal function, oxygenation, and RBF in patients with atherosclerotic renal artery stenosis undergoing PTRA...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28916408/robot-assisted-kidney-transplantation-the-european-experience
#14
Alberto Breda, Angelo Territo, Luis Gausa, Volkan Tuğcu, Antonio Alcaraz, Mireia Musquera, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Luis Guirado, Carma Facundo, Nicolas Doumerc
BACKGROUND: Robot-assisted kidney transplantation (RAKT) has recently been introduced to reduce the morbidity of open kidney transplantation (KT). OBJECTIVE: To evaluate perioperative and early postoperative RAKT outcomes. DESIGN, SETTING AND PARTICIPANTS: This was a multicenter prospective observational study of 120 patients who underwent RAKT, predominantly with a living donor kidney, in eight European institutions between July 2015 and May 2017, with minimum follow-up of 1 mo...
September 12, 2017: European Urology
https://www.readbyqxmd.com/read/28916346/radiofrequency-ablation-of-t1a-renal-cell-carcinomas-within-renal-transplant-allografts-oncologic-outcomes-and-graft%C3%A2-viability
#15
Derek W Cool, John R Kachura
PURPOSE: To evaluate oncologic outcomes and graft viability after percutaneous RF ablation of renal cell carcinoma (RCC) developing within renal transplant allografts. MATERIALS AND METHODS: A single-institution, retrospective study reviewed all patients treated with RF ablation for RCC between February 2004 and May 2016. Ten patients were identified (age 49.6 y ± 12.6; 9 men, 1 woman) with 12 biopsy-confirmed RCC tumors within the allograft (all T1a, mean diameter 2...
September 13, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28915690/efficacy-and-safety-of-a-reduced-calcineurin-inhibitor-dose-combined-with-mycophenolate-mofetil-in-liver-transplant-patients-with-chronic-renal-dysfunction
#16
Pusen Wang, Weitao Que, Hao Li, Lvnan Yan, Zhiren Fu, Qifa Ye, Guihua Chen, Kefeng Dou, Shichun Lu, Zhanyu Yang, Zhijun Zhu, Zhihai Peng, Lin Zhong
Calcineurin inhibitors (CNIs) are frequently given at a reduced dose in combination with mycophenolate mofetil (MMF) to avoid nephrotoxicity, but the optimal reduction in CNI dose has not been established. In this prospective, open-label, multicenter study, liver transplant recipients with chronic renal dysfunction who were administered a CNI-based immunosuppressive regimen were included in the intent-to-treat (ITT) population. The primary endpoint was declination in renal function, which was defined as a ≥ 20% decrease in the glomerular filtration rate during the year following regimen adjustment...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28915510/drug-eluting-vs-bare-metal-stents-in-patients-with-chronic-kidney-disease-and-coronary-artery-disease-insights-from-a-systematic-review-and-meta-analysis
#17
Alexander Volodarskiy, Sunil Kumar, Radoslaw Pracon, Mandeep Sidhu, Evgeny Kretov, Tomasz Mazurek, Olga Bockeria, Upendra Kaul, Sripal Bangalore
BACKGROUND: Most drug-eluting stent (DES) trials have excluded patients with chronic kidney disease (CKD). The efficacy of DES implantation in patients with CKD is therefore not known. OBJECTIVES: To evaluate the outcomes with DES vs bare-metal stent (BMS) implantation in patients with CKD. METHODS AND RESULTS: MEDLINE, EMBASE, and CENTRAL were searched for studies including at least 100 patients with CKD (estimated glomerular filtration rate ≤60 mL/min/1...
September 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28915230/albuminuria-and-endothelial-dysfunction-in-patients-with-non-diabetic-chronic-kidney-disease
#18
Meng-Jie Huang, Ri-Bao Wei, Jing Zhao, Ting-Yu Su, Qing-Ping Li, Xi Yang, Xiang-Mei Chen
BACKGROUND Albuminuria has been associated with cardiovascular events, but whether such an association can be explained by endothelial dysfunction is not fully understood. In this study, we examined the relationship between the urine albumin-to-creatinine ratio (UACR) and biomarkers of endothelial function in patients with chronic kidney disease (CKD). MATERIAL AND METHODS The cross-sectional associations of renal dysfunction and UACR with procoagulant and inflammatory factors were evaluated for 151 consecutive CKD (stage 3-5) patients...
September 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28914962/impaired-phosphate-tolerance-revealed-with-an-acute-oral-challenge
#19
Mandy E Turner, Christine A White, Wilma M Hopman, Emilie C Ward, Paul S Jeronimo, Michael A Adams, Rachel M Holden
Elevated serum phosphate is consistently linked with cardiovascular disease (CVD) events and mortality in the setting of normal and impaired kidney function. However, serum phosphate does not often exceed the upper limit of normal until glomerular filtration rate (GFR) falls below 30 mL/min/m(2) . It was hypothesized that the response to an oral, bioavailable phosphate load will unmask impaired phosphate tolerance, a maladaptation not revealed by baseline serum phosphate concentrations. In this study rats with varying kidney function as well as normo-phosphatemic human subjects, with inulin-measured GFR (13...
September 15, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28914638/long-term-risk-and-predictors-of-cardiovascular-death-in-stable-coronary-artery-disease-the-coronor-study
#20
Christophe Bauters, Olivier Tricot, Thibaud Meurice, Nicolas Lamblin
BACKGROUND: There is limited knowledge on the residual risk of cardiovascular death (CVD) in patients with stable coronary artery disease (CAD) who receive modern secondary prevention. Our aim was to analyze the causes of death and to determine predictors of CVD in the 5-year CORONOR registry. METHODS: We studied 4184 consecutive CAD outpatients who were free from any myocardial infarction (MI) or coronary revascularization for more than 1 year at inclusion. Antithrombotics were prescribed in 99%, statins in 92%, inhibitors of renin-angiotensin system in 82%, and β-blockers in 79%; 86% had prior coronary revascularization...
September 13, 2017: Coronary Artery Disease
keyword
keyword
11385
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"