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https://www.readbyqxmd.com/read/29890021/clinical-characteristics-risk-factors-and-outcome-of-tuberculosis-in-kidney-transplant-recipients-a-multicentric-case-control-study-in-a-low-endemic-area
#1
Julien Gras, Nathalie De Castro, Claire Montlahuc, Laure Champion, Anne Scemla, Marie Matignon, Marie Lachâtre, Laurent Raskine, Nathalie Grall, Marie Noëlle Peraldi, Jean Michel Molina
OBJECTIVES: Tuberculosis (TB) is a rare but life-threatening infection after solid organ transplant. The present study was undertaken to assess the clinical features, risk factors and outcome of TB after kidney transplantation in a low-prevalence area. METHODS: We conducted a retrospective study, describing all kidney transplant recipients diagnosed with TB between 2005 and 2015 in three French centers. For each TB case, two controls without TB were identified and matched by center, age, transplant date, and birth country...
June 11, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29870786/scientific-rationale-for-traditional-use-of-plants-to-treat-tuberculosis-in-the-eastern-region-of-the-or-tambo-district-south-africa
#2
B Madikizela, L J McGaw
ETHNOPHARMACOLOGICAL RELEVANCE: Tuberculosis (TB) remains a major health problem for humans worldwide, and was responsible for 1.4 million human deaths in 2015 alone. Although there is treatment for TB, emerging multi-drug, extensively drug and totally drug resistant forms of this disease, as well as co-infection with human immunodefiency virus (HIV) continue to worsen the situation. South Africa is among countries with reported traditional use and published documentation of such knowledge concerning the use of plants against TB...
June 2, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29866727/impact-of-the-pretransplant-dialysis-modality-on-kidney-transplantation-outcomes-a-nationwide-cohort-study
#3
Huan-Tang Lin, Fu-Chao Liu, Jr-Rung Lin, See-Tong Pang, Huang-Ping Yu
OBJECTIVE: Most patients with uraemia must undergo chronic dialysis while awaiting kidney transplantation; however, the role of the pretransplant dialysis modality on the outcomes of kidney transplantation remains obscure. The objective of this study was to clarify the associations between the pretransplant dialysis modality, namely haemodialysis (HD) or peritoneal dialysis (PD), and the development of post-transplant de novo diseases, allograft failure and all-cause mortality for kidney-transplant recipients...
June 4, 2018: BMJ Open
https://www.readbyqxmd.com/read/29862957/robot-assisted-lobectomy-for-pulmonary-tuberculosis-in-a-case-with-immunosuppression-after-kidney-transplantation
#4
Piotr K Yablonskii, Armen O Avetisyan, Igor V Vasilev, Grigorii G Kudriashov, Oleg N Resnik, Ludmila I Archakova, Larisa D Kiruhina, Tatyana A Novickaya, Alexey D Ushkov
No abstract text is available yet for this article.
June 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29850312/rifampicin-in-nontuberculous-mycobacterial-infections-acute-kidney-injury-with-hemoglobin-casts
#5
Rishi Kora, Sergey V Brodsky, Tibor Nadasdy, Dean Agra, Anjali A Satoskar
Rifampicin is a key component of multidrug regimens not only for tuberculosis, but also nontuberculous mycobacterial infections (NTM) which are on the rise worldwide. Knowledge of the toxicity profile is important. Hepatotoxicity is a well-known side effect of Rifampicin necessitating regular liver function monitoring during therapy. Acute kidney injury (AKI) is a relatively rare complication, usually resulting from allergic interstitial nephritis (AIN). Rifampicin-induced intravascular hemolysis resulting in hemoglobinuria and AKI is even more uncommon, especially in Western countries with low prevalence of mycobacterial infections...
2018: Case Reports in Nephrology
https://www.readbyqxmd.com/read/29793873/executive-summary-of-the-gesida-consensus-document-on-control-and-monitoring-of-hiv-infected-patients
#6
(no author information available yet)
The continuous increase in our knowledge of HIV medicine and antiretroviral treatment has led us to draft specific consensus documents focused on topics other than antiretroviral therapy, such as treatment of opportunistic diseases, pre- and post-exposure prophylaxis, metabolic abnormalities, treatment of HBV or HCV coinfection, treatment of patients coinfected with tuberculosis, osteoporosis, kidney disorders, and cardiovascular risk. Accordingly, the AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology has promoted the drafting of this consensus document on the control and monitoring of adult patients infected with HIV...
May 21, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29791554/chest-x-ray-and-chest-ct-findings-in-patients-diagnosed-with-pulmonary-tuberculosis-following-solid-organ-transplantation-a-systematic-review
#7
Irai Luis Giacomelli, Roberto Schuhmacher Neto, Edson Marchiori, Marisa Pereira, Bruno Hochhegger
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: "tuberculosis"; "transplants"; "transplantation"; "mycobacterium"; and "lung". The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Saúde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publication, that met the selection criteria in their title, abstract, or body of text...
April 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29790316/chronic-non-healing-ulcer-of-the-oral-cavity-tuberculosis-or-carcinoma
#8
Neeti Swarup, Meghanand T Nayak, Nitali Arun, S Chandarani, Zoya Chowdhary
Tuberculosis is a chronic granulomatous lesion, which primarily has an affinity for the lungs. It can involve other sites like lymph nodes, kidney, oral cavity. Infection of the oral cavity by M. tuberculosis can be as a Primary infection or as a Secondary infection. Primary presentation of oral tuberculosis is in the form of the chronic non healing ulcer. A Primary infection or an Asymptomatic Secondary infection can impose a great diagnostic dilemma, as it may mimic neoplasia. Here we present a case of a 32-year-old asymptomatic female with secondary infection...
May 2018: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29737591/expression-profile-of-markers-of-oxidative-stress-injury-and-apoptosis-in-anti-tuberculosis-drugs-induced-nephrotoxicity
#9
Radhika Sharma, Priya Battu, Mandakini Singla, Neha Goyal, Vijay L Sharma
AIM: Isoniazid (INH), Rifampicin (RIF) and Pyrazinamide (PZA) are part of first-line anti-tuberculosis therapy used against infection caused by Mycobacterium tuberculosis. However these drugs are known to be potentially harmful as these are associated with numerous side effects and when taken together their harmful outcomes are elevated in a synergistic manner. Identification of possible mechanism underlying RIF+INH+PZA induced nephrotoxicity may be advantageous in developing strategies to prevent their toxic implications...
May 8, 2018: Nephrology
https://www.readbyqxmd.com/read/29731582/granuloma-of-the-labial-minor-salivary-glands-in-tuberculosis
#10
Adriana Handra-Luca
Minor salivary gland granuloma is rare in tuberculosis. We present a case of labial minor salivary gland granulomas occurring in the course of tuberculosis along with skin, mediastinal and liver granulomas. The patient (46-year-old man) presented with asthenia, nocturne transpiration, weight loss and compressive thoracic adenopathies. The angiotensin I converting enzyme was elevated as well as calcemia. The QuantiFERON test and culture of a mediastinal specimen were positive for Mycobacterium tuberculosis ...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29722039/mortality-from-adverse-drug-reaction-related-hospitalizations-in-south-west-ethiopia-a-cross-sectional-study
#11
M T Angamo, L Chalmers, C M Curtain, D Yilma, L Bereznicki
WHAT IS KNOWN AND OBJECTIVE: Adverse drug reactions (ADRs) are an important cause of mortality during medical care. To our knowledge, no Ethiopian studies have reported on mortality due to ADRs in patients presenting to hospital from the community setting. The aim of this study was to determine the mortality rate attributable to ADRs in patients presenting to hospital, identify drugs implicated in the ADR-related deaths and identify factors contributing to ADR-related mortality at Jimma University Specialised Hospital (JUSH), south-west Ethiopia METHODS: This cross-sectional study included 1001 patients aged ≥18 years consecutively admitted to medical wards from May 2015 to August 2016...
May 2, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29707388/risk-factors-and-co-morbidities-associated-with-changes-in-renal-function-among-antiretroviral-treatment-na%C3%A3-ve-adults-in-south-africa-a-chart-review
#12
Shirelle Assaram, Tivani P Mashamba-Thompson, Nombulelo P Magula
Introduction: Our systematic scoping review has demonstrated a research gap in antiretroviral treatment (ART) nephrotoxicity as well as in the long-term outcomes of renal function for patients on ART in South Africa. Bearing in mind the high prevalence of human immunodeficiency virus (HIV) in South Africa, this is of great concern. Objectives: To determine the risk factors and co-morbidities associated with changes in renal function in HIV-infected adults in South Africa...
2018: Southern African Journal of HIV Medicine
https://www.readbyqxmd.com/read/29704591/antimycobacterial-and-hypolipemiant-activities-of-bidens-odorata-cavanilles
#13
Karla Mariela Hernández-Sánchez, Leticia Garduño-Siciliano, Julieta Luna-Herrera, L Gerardo Zepeda-Vallejo, Selene Lagunas-Rivera, G Esthefania García-Gutiérrez, María Elena Vargas-Díaz
ETHNOPHARMACOLOGICAL RELEVANCE: Bidens odorata Cavanilles is a medicinal and edible plant known as "mozote blanco, aceitilla, acahual, mozoquelite" which is traditionally used in Mexico as a diuretic, hypoglycaemic, anti-inflammatory, antipyretic, antitussive, to treat gastrointestinal disorders, kidney pain, and lung or respiratory diseases. AIM OF THE STUDY: This research study was aimed at phytochemical analysis of aerial extracts of B. odorata for antimycobacterial and lipid-lowering activities...
April 25, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29692991/rapid-and-complete-remission-of-class-iv-lupus-nephritis-with-massive-wire-loop-lesions
#14
Tomo Suzuki, Ryutaro Matsumura, Hiroshi Kitamura, Yugo Shibagaki
Class IV lupus nephritis (LN) often has a poorer prognosis than other classes. However, class IV LN has various phenotypes, including not only segmental and global types but also others. We present the case of a 29-year-old woman with class IV-G LN who had an early response to glucocorticoid monotherapy. In addition, multiple lung nodules such as miliary tuberculosis (TB) were detected on computed tomography. All cultures of sputum, gastric fluid, and bone marrow were negative. A kidney biopsy revealed diffuse endocapillary proliferative glomerulonephritis with marked subendothelial deposition...
January 2018: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/29692592/revisiting-renal-amyloidosis-with-clinicopathological-characteristics-grading-and-scoring-a-single-institutional-experience
#15
Abhiram Kalle, Archana Gudipati, Sree Bhushan Raju, Karthik Kalidindi, Swarnalatha Guditi, Gangadhar Taduri, Megha S Uppin
INTRODUCTION: Kidney involvement is a major cause of mortality in systemic amyloidosis. Glomerulus is the most common site of deposition in renal amyloidosis, and nephrotic syndrome is the most common presentation. Distinction between AA and AL is done using immunofluorescence (IF) and immunohistochemistry (IHC). Renal biopsy helps in diagnosis and also predicting the clinical course by applying scoring and grading to the biopsy findings. MATERIALS AND METHODS: The study includes all cases of biopsy-proven renal amyloidosis from January 2008 to May 2017...
April 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29659613/diagnostic-delay-and-mortality-of-active-tuberculosis-in-patients-after-kidney-transplantation-in-a-tertiary-care-hospital-in-china
#16
Wei Wu, Meifang Yang, Min Xu, Cheng Ding, Yongtao Li, Kaijin Xu, Jifang Shen, Lanjuan Li
TB infection in patients after kidney transplantation remains a concern in a successful long-term outcome. This retrospective, descriptive study was performed on tuberculosis infection after kidney transplantation in the Department of Infectious Disease of the First Affiliated Hospital of Zhejiang University, a tertiary care hospital in China, from January 2011 to April 2017, with the aim to explain the clinical features of active tuberculosis after kidney transplantation and explore the correlated factors for diagnostic delay and mortality...
2018: PloS One
https://www.readbyqxmd.com/read/29656530/mycobacterium-tuberculosis-after-solid-organ-transplantation-a-review-of-more-than-2000-cases
#17
Cybele Lara R Abad, Raymund R Razonable
BACKGROUND: Mycobacterium tuberculosis (TB) is a common pathogen worldwide, and it may cause significant infection after solid organ transplantation (SOT). We reviewed all reported TB cases to provide an update on its epidemiology, clinical presentation, management, and outcome after SOT. METHODS: MEDLINE, EMBASE, and OVID were reviewed from January 1, 1998, to December 31, 2016, using keywords tuberculosis and solid organ transplant or transplantation. RESULTS: There were 187 publications reporting 2082 cases of TB among kidney (n = 1719), liver (n = 253), heart (n = 77), lung (n = 25), and kidney-pancreas (n = 8) recipients...
April 15, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29622669/secular-trends-in-infection-related-mortality-after-kidney-transplantation
#18
Susanna Kinnunen, Pauli Karhapää, Auni Juutilainen, Patrik Finne, Ilkka Helanterä
BACKGROUND AND OBJECTIVES: Infections are the most common noncardiovascular causes of death after kidney transplantation. We analyzed the current infection-related mortality among kidney transplant recipients in a nationwide cohort in Finland. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Altogether, 3249 adult recipients of a first kidney transplant from 1990 to 2012 were included. Infectious causes of death were analyzed, and the mortality rates for infections were compared between two eras (1990-1999 and 2000-2012)...
May 7, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29617083/retroperitoneal-laparoscopic-nephroureterectomy-with-distal-and-intramural-ureter-resection-for-a-tuberculous-non-functional-kidney
#19
Canqiang Li, Yi Yang, Le Xu, Minjie Qiu
OBJECTIVE: To evaluate the safety and feasibility of total retroperitoneal laparoscopic nephroureterectomy with urinary-bladder junction resection for a tuberculous non-functional kidney. MATERIALS AND METHODS: A total of 27 individuals diagnosed with unilateral non-functional kidney secondary to tuberculosis were treated between June 2011 and June 2015. All patients had normal renal function on the contralateral side and underwent the standard four-drug anti-tuberculosis treatment for at least four weeks before surgery...
April 3, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29605219/bacterial-pneumonia-in-kidney-transplant-recipients
#20
REVIEW
D Wilmes, E Coche, H Rodriguez-Villalobos, N Kanaan
Bacterial pathogens are the most frequent cause of pneumonia after transplantation. Early after transplantation, recipients are at higher risk for nosocomial infections. The most commonly encountered pathogens during this period are gram-negative bacilli (Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa …), but gram-positive coccus such as Staphylococcus aureus or Streptococcus pneumoniae and anaerobic bacteria can also be found. Empirical antibiotic therapy should be guided by previous colonisation of the recipient and bacterial resistance pattern in the hospital...
April 2018: Respiratory Medicine
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