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https://www.readbyqxmd.com/read/29339819/ancient-human-migrations-to-and-through-jammu-kashmir-india-were-not-of-males-exclusively
#1
Indu Sharma, Varun Sharma, Akbar Khan, Parvinder Kumar, Ekta Rai, Rameshwar N K Bamezai, Miguel Vilar, Swarkar Sharma
Jammu and Kashmir (J&K), the Northern most State of India, has been under-represented or altogether absent in most of the phylogenetic studies carried out in literature, despite its strategic location in the Himalayan region. Nonetheless, this region may have acted as a corridor to various migrations to and from mainland India, Eurasia or northeast Asia. The belief goes that most of the migrations post-late-Pleistocene were mainly male dominated, primarily associated with population invasions, where female migration may thus have been limited...
January 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29333015/a-profile-of-pediatric-solid-tumors-a-single-institution-experience-in-kashmir
#2
Namita Sharma, Ayesha Ahmad, Gull M Bhat, Sheikh A Aziz, Mohammad Maqbool Lone, Nisar A Bhat
Aims: The purpose of this retroprospective study was to study the epidemiological characteristics and outcomes of children with solid tumors at our institution. Subjects and Methods: Three hundred and three pediatrics patients registered at Regional Cancer Centre (RCC), Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Kashmir, between January 2008 and June 2014, were analyzed with regard to demographic status, presenting complaints, investigations, treatment, morbidity, and outcomes...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29333012/squamous-cell-carcinoma-lung-with-skeletal-muscle-involvement-a-8-year-study-of-a-tertiary-care-hospital-in-kashmir
#3
Javvid Muzamil, Shumail Bashir, Faisal R Guru, Firdousa Nabi, Gull Mohammad Bhat
Aims: Lung cancer is the most common malignancy throughout the world. Nonsmall cell lung cancer (NSCLC) is the most common type, and squamous cell type is most common in India. Mostly, patients present with chest-related symptoms and signs. Isolated skeletal muscle metastasis (ISMM) is rarely seen. The aim was to see muscle metastasis and its prognosis. Materials and Methods: We are presenting our data of 8 years about this common malignancy with relation to muscle metastasis, either alone or with other system metastasis...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29304848/effectiveness-and-safety-of-ferric-carboxymaltose-compared-to-iron-sucrose-in-women-with-iron-deficiency-anemia-phase-iv-clinical-trials
#4
Amreen Naqash, Rifat Ara, Ghulam N Bader
BACKGROUND: Iron deficiency anemia (IDA) is a significant problem worldwide particularly in women. The aim of the study was to evaluate the effectiveness and safety of intravenous ferric carboxymaltose (FCM) in comparison to iron sucrose (IS) in women with IDA. METHOD: Two hundred patients at Department of Obstetrics and Gynaecology, Sher-i-Kashmir Institute of Medical Sciences Medical College and Hospital, Jammu & Kashmir, India identified with IDA were enrolled for the study...
January 5, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29291237/genotyping-and-phylogenetic-analysis-of-infectious-bronchitis-virus-isolated-from-broiler-chickens-in-kashmir
#5
Rafia Parveen, Iqra Farooq, Showkat Ahangar, Salik Nazki, Zahoor Dar, Tanveer Dar, Shayaib Kamil, Pervaiz Dar
Infectious bronchitis virus (IBV) is responsible for significant economic losses to the poultry industry across the world. The enormous genetic diversity of IBV poses difficulty in diagnosing and controlling the virus. To understand the nature of IBV prevalent in the Kashmir Himalayas, we characterized two field strains, isolated from non-immunized broiler chickens, by sequence and phylogenetic analysis of S1 subunit of the spike glycoprotein. The analysis revealed both the isolates are identical to each other, with nucleotide and amino acid sequence identities of 99...
December 2017: Virusdisease
https://www.readbyqxmd.com/read/29281971/small-rna-profiling-for-identification-of-mirnas-involved-in-regulation-of-saponins-biosynthesis-in-chlorophytum-borivilianum
#6
Monika Kajal, Kashmir Singh
BACKGROUND: MicroRNAs act as molecular regulator of cell signaling, plant growth and development, and regulate various primary and secondary plant metabolic processes. In the present study, deep sequencing of small RNAs was carried out to identify known and novel miRNAs from pharmaceutically important plant, Chlorophytum borivilianum. RESULTS: Total 442 known miRNAs and 5 novel miRNAs were identified from young leaf small RNA library. Experimental validation with stem loop RT-PCR confirmed the in silico identification...
December 28, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29278931/cyp1a2-1f-gene-variant-alkaline-salt-tea-intake-and-risk-of-esophageal-squamous-cell-carcinoma
#7
Idrees Ayoub Shah, Promila Mehta, M Maqbool Lone, Malik Tariq Rasool, Ghulam Nabi Lone, G M Gulzar, Farooq Ahmad Ganie, Mohmmad Akbar Bhat, Nazir Ahmad Dar
Unlike many other cancers, the relationship of CYP1A2*1F (rs762551) polymorphism with esophageal squamous cell carcinoma (ESCC) risk has not been assessed so far. To evaluate its association with ESCC, we conducted a case control study in Kashmir, India, a high risk region. We recruited 404 histopathologically confirmed ESCC cases and 404 controls, individually matched for sex, age and residence to the respective cases. Information was obtained on dietary, lifestyle and environmental factors in face to face interviews using a structured questionnaire from each subject...
January 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29275342/prevalence-and-possible-factors-associated-with-anaemia-and-vitamin-b-12-and-folate-deficiencies-in-women-of-reproductive-age-in-pakistan-analysis-of-national-level-secondary-survey-data
#8
Sajid Soofi, Gul Nawaz Khan, Kamran Sadiq, Shabina Ariff, Atif Habib, Sumra Kureishy, Imtiaz Hussain, Muhammad Umer, Zamir Suhag, Arjumand Rizvi, Zulfiqar Bhutta
OBJECTIVE: To determine the prevalence and possible factors associated with anaemia, and vitamin B12 and folate deficiencies in women of reproductive age (WRA) in Pakistan. METHODS: A secondary analysis was conducted on data collected through the large-scale National Nutrition Survey in Pakistan in 2011. Anaemia was defined as haemoglobin levels <12 g/dL, vitamin B12 deficiency as serum vitamin B12 levels of <203 pg/mL (150 pmol/L) and folate deficiency as serum folate levels <4 ng/mL (10 nmol/L)...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29233639/role-of-the-functional-polymorphism-of-survivin-gene-31g-c-and-risk-of-breast-cancer-in-a-north-indian-population
#9
Ishrat Rasool, Dil Afroze, Khursheed Alam Wani, Adfar Yousuf, Imtiyaz Ahmad Bhat, Bilal Rah, Sheeraz Un Nazir, Showket Hussain, Shweta Dubey
INTRODUCTION: Survivin is an apoptosis inhibitor and plays a primary role in cancer development and progression. One of the most common polymorphism of the survivin promoter -31G/C (rs9904341) influences its expression and is associated with the risk of cancer development. This study was conducted to explore survivin promoter gene -31G/C (rs9904341) polymorphism and the risk of breast cancer. PATIENTS AND METHODS: The study group included 190 pathologically confirmed breast cancer patients, in addition to 200 distinct cancer-free controls from Jammu and Kashmir region of India, where breast cancer is the most common cancer in women...
November 23, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29204387/pattern-of-skin-diseases-and-occupational-dermatoses-in-veterinarians-and-veterinary-workers-of-kashmir
#10
Sumaya Zeerak, Iffat Hassan, Farhan Rasool, Yasmeen J Bhat, Safia Bashir
Background: Across the globe, skin disorders represent a frequent occupational concern for many health professionals including veterinarians and there is a serious impact of skin diseases on their lives and careers. But little is known about the prevalence and distribution of skin diseases (especially occupational) within this important professional group across Asia, especially India. Materials and Methods: The study was a cross-sectional study carried out over a period of one year in which veterinarians and veterinary workers of Kashmir valley were screened for various skin diseases and occupational dermatoses...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29200670/clinico-radiological-and-pathological-characteristics-of-inflammatory-myofibroblastic-tumors-in-children-a-retrospective-study
#11
Mohamad Hussain Mir, Waseem Dar, Sheikh Aejaz Aziz, Gul Mohamad, Burhan Wani
Purpose: Inflammatory myofibroblastic tumors (IMTs) are rare, benign lesions most often seen in the lung of young adults but can occur in children, in various sites. They mimic, clinically and radiologically, malignant tumors - especially sarcomas and lymphomas. The aim was to review the clinical, radiological, and pathological data of children with a diagnosis of IMT referred to our department. Materials and Methods: This retrospective study was conducted at the Department of Medical and Paediatric Oncology, Regional Cancer Centre, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India from January 2014 to December 2015...
July 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29191238/ethnopharmacological-studies-of-indigenous-plants-in-kel-village-neelum-valley-azad-kashmir-pakistan
#12
Khawaja Shafique Ahmad, Abdul Hamid, Fahim Nawaz, Mansoor Hameed, Farooq Ahmad, Jiabin Deng, Noreen Akhtar, Ambreen Wazarat, Sehrish Mahroof
BACKGROUND: This explorative study was undertaken for the first time in Kel village located in the Upper Neelum Valley, Azad Kashmir, Pakistan. The purpose was to document the indigenous knowledge of the native people used in the preparation of herbal medicines. METHODS: To get the data on traditional uses of medicinal plants, 20 informants were interviewed. Quantitative ethnobotanical indices, i.e., use value (UV), relative frequencies of citation (RFC), informant consensus factor (Fic), fidelity level (FL), data matrix ranking (DMR), preference ranking (PR), and jaccard index (JI), were calculated for the recorded medicinal plants...
December 1, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29188775/isolation-and-characterization-of-antibiotic-producing-bacterial-strains-from-red-soil-of-himalayan-region-of-pakistan
#13
Bushra Uzair, Neelam Firdous, Barkat Ali Khan, Samiullah Khan, Sammer Fatima, Rehana Kausar, Asma Bano
The emergence of multi drug resistant microbial pathogens has become a global health challenge and set a dire requirement of searching new effective antimicrobials. Soil is an ultimate reservoir of biologically active micro flora, which harbors trillions of microbial strains producing compounds of commercial interest. Hence aim of the present study was an attempt to isolate and identify the antibiotic producing microbial strains from the red soil of Himalayan an unexplored region of Pakistan. In this study from 10 different soil samples only one bacterial strain was isolated capable of antimicrobial activity...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29133097/biological-and-textural-properties-of-underutilized-exudate-gums-of-jammu-and-kashmir-india
#14
Mudasir Bashir, Tuba Usmani, Sundaramoorthy Haripriya, Tanveer Ahmed
Three different exudate gums were studied for their in-vitro antioxidant activity, functional and textural properties. In-vitro antioxidant activity of the gum exudates was evaluated in terms of DPPH radical scavenging, hydroxyl radical scavenging, reducing power and phenolic content assays. Among the gum exudates, almond gum exhibited maximum DPPḢ inhibition of 35.52±1.125% followed by apricot gum and gum arabic at the concentration of 1mg/mL. Gum arabic had significantly higher reducing power than the other exudate gums...
November 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29114137/gross-and-histopathological-alterations-associated-with-cystic-echinococcosis-in-small-ruminants
#15
Akeel Bashir Beigh, Mohmommad Maqbool Darzi, Samina Bashir, Bisma Kashani, Aazima Shah, Showkat Ahmad Shah
Hydatidosis, an important parasitic zoonoses is a major public health as well as economic concern throughout the world. A total of 2100, sheep (2052) and goats (48), slaughtered or spontaneously dead, from various areas of Kashmir valley were screened for the presence of hydatidosis. Out of 2100 cases, 85 were positive for hydatidosis. The frequently infected organs were lungs and liver. The liver was observed to be the most frequently infected organ with relative prevalence of 61.17% followed by lungs (38...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29110863/assessment-of-metabolic-syndrome-in-kashmiri-population-with-type-2-diabetes-employing-the-standard-criteria-s-given-by-who-ncepatp-iii-and-idf
#16
Shafat Lone, Kouser Lone, Saika Khan, Rafiq Ahmed Pampori
BACKGROUND: Around 20-25 percent of the world's adult populations have the metabolic syndrome and they are twice as likely to die from heart attack or stroke compared with people without the syndrome. The World Health Organization proposed a definition for the metabolic syndrome in 1998 and later on NCEP ATPIII and IDF provided new definitions of this syndrome in 2001 and 2003 respectively. Very few studies have compared the different definitions to diagnose the metabolic syndrome in type two diabetics in India while as for Kashmir valley no such documented study has been carried out till date...
December 2017: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/29082026/prevalence-of-anxiety-depression-and-post-traumatic-stress-disorder-in-the-kashmir-valley
#17
Tambri Housen, Annick Lenglet, Cono Ariti, Showkat Shah, Helal Shah, Shabnum Ara, Kerri Viney, Simon Janes, Giovanni Pintaldi
BACKGROUND: Following the partition of India in 1947, the Kashmir Valley has been subject to continual political insecurity and ongoing conflict, the region remains highly militarised. We conducted a representative cross-sectional population-based survey of adults to estimate the prevalence and predictors of anxiety, depression and post-traumatic stress disorder (PTSD) in the 10 districts of the Kashmir Valley. METHODS: Between October and December 2015, we interviewed 5519 out of 5600 invited participants, ≥18 years of age, randomly sampled using a probability proportional to size cluster sampling design...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29063198/dental-fluorosis-nutritional-status-kidney-damage-and-thyroid-function-along-with-bone-metabolic-indicators-in-school-going-children-living-in-fluoride-affected-hilly-areas-of-doda-district-jammu-and-kashmir-india
#18
Arjun L Khandare, Shankar Rao Gourineni, Vakdevi Validandi
A case-control study was undertaken among the school children aged 8-15 years to know the presence and severity of dental fluorosis, nutrition and kidney status, and thyroid function along with bone metabolic indicators in Doda district situated at high altitude where drinking water was contaminated and heat stress. This study included 824 participants with an age of 8-15 years. The results of the study reviled that dental fluorosis was significantly higher in affected than control area children. Urinary fluoride was significantly higher (p < 0...
October 23, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29062216/impending-gangrene-of-fingers-by-constriction-bands-of-mother-s-hair-mistaken-as-pernio-by-parents-a-case-series-of-10-infants
#19
Towseef Ahmad Bhat, Zameer Ali, Tarseem Lal Moten, Aabid Hussain Sofi, Furqaan Mir, Amara Gulzar
BACKGROUND: Long harsh winter in Kashmir Valley increase the incidence of pernio in children so much that common people consider every hand swelling as pernio. METHODS: 10 Infants over two years were brought to our hospital as cases of pernio involving fingers. RESULTS: All the infants came out to be cases of impending gangrene due to mother's hair as constriction bands around fingers. CONCLUSION: Impending gangrene of fingers in infants due to mother hair as constriction band is very rare...
October 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29057960/contrasting-glacier-responses-to-recent-climate-change-in-high-mountain-asia
#20
Akiko Sakai, Koji Fujita
Recent studies of Asian glaciers have shown that glaciers in eastern Karakoram and West Kunlun have been slightly gaining mass while those in nearby Jammu Kashmir and Himalayas are losing mass, at rates of more than 0.5 m w.e.yr(-1) and about 0.3 m w.e.yr(-1), respectively. Two possible explanations have been proposed for this difference in glacier behaviour: spatial heterogeneity in climate change (climatic forcing) or differing glacier responses to climate change (glacier response). However, neither explanation has strong supporting evidence...
October 20, 2017: Scientific Reports
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