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https://www.readbyqxmd.com/read/29344466/comparison-of-autonomic-function-before-and-after-surgical-intervention-in-patients-with-temporal-lobe-epilepsy
#1
Navita Choudhary, Kishore K Deepak, Poodipedi S Chandra, Shalini Bhatia, Rajesh Sagar, Ashok K Jaryal, Ravindra M Pandey, Manjari Tripathi
Background and Purpose: Refractory temporal lobe epilepsy (TLE) is commonly associated with imbalances in cardiovascular (CV) parasympathetic and sympathetic functions, which are treated using TLE surgery. We investigated the effect of hemispheric lateralization of seizure foci on autonomic CV functions before and after TLE surgery. Methods: The study was conducted on patients with left TLE (LTLE, n = 23) and right TLE (RTLE, n = 30) undergoing unilateral TLE surgery...
December 2017: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/29340931/vascutrainer-a-mobile-and-disposable-bioreactor-system-for-the-conditioning-of-tissue-engineered-vascular-grafts
#2
Frederic Wolf, Diana M Rojas González, Ulrich Steinseifer, Markus Obdenbusch, Werner Herfs, Christian Brecher, Stefan Jockenhoevel, Petra Mela, Thomas Schmitz-Rode
In vitro tissue engineering of vascular grafts requires dynamic conditioning in a bioreactor system for in vitro tissue maturation and remodeling to receive a mechanically adequate and hemocompatible implant. The goal of the current work was to develop a bioreactor system for the conditioning of vascular grafts which is (i) able to create a wide range of flow, pressure and frequency conditions, including physiological ones; (ii) compact and easy to assemble; (iii) transportable; (iv) disposable. The system is driven by a small centrifugal pump controlled via a custom-made control unit, which can also be operated on batteries to allow for autonomous transportation...
January 16, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29335614/reliability-of-pulse-waveform-separation-analysis-responses-to-an-orthostatic-challenge
#3
Lee Stoner, Keeron Stone, Erik D Hanson, James Faulkner, Simon Fryer, Daniel Credeur
Cardiovascular autonomic nervous system function can be assessed using an orthostatic challenge to induce arterial wave reflection. While arterial reflection is typically estimated using a central augmentation index, a superior estimation can be obtained using pulse wave separation analysis to estimate the aortic backward pressure wave (Pb). However, to be of value in a clinical or research setting, an assessment tool must be precise (reliable). Therefore, this study sought to determine the measurement precision of Pb responses to a modified tilt-table test...
January 15, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29331885/autonomously-hyperfunctioning-cystic-nodule-harbouring-thyroid-carcinoma-case-report-and-literature-review
#4
Maria João Lima, Virgínia Soares, Pedro Koch, Artur Silva, António Taveira-Gomes
INTRODUCTION: Hyperthyroidism is rarely associated with malignancy, but it cannot rule out thyroid cancer. Although there is published data describing this coexistence, thyroid carcinomas inside autonomously functioning nodules are uncommon. PRESENTATION OF CASE: A 49-year-old woman presented with a cervical mass, unexplained weight loss and anxiousness, sweating and insomnia. On physical examination, she had a palpable left thyroid nodule. Thyroid function tests showed suppressed TSH (<0,1 uUI/mL), thyroxine 1,44 ng/dL (normal range 0,70-1,48) and triiodothyronine 4,33 pg/mL (normal range 1,71-3,71)...
January 8, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29319794/an-observational-analysis-of-insulinoma-from-1-single-institution
#5
Zhixuan Zeng, Shuhong Hu, Shiying Shao
Background: Insulinoma is the commonest functioning pancreatic neuroendocrine tumor causing hyperinsulinemic hypoglycemia. This study is aimed to evaluate the clinical features, preoperative laboratory and imaging diagnosis, and pathologic findings of insulinoma. Methods: Data of the patients from 2001 to 2016 diagnosed as insulinoma in Tongji Hospital, China were retrospectively extracted and analyzed. Results: A total of 40 patients were diagnosed as insulinoma with a male/female ratio of 0...
January 8, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29315657/dysautonomy-in-different-death-risk-groups-rassi-score-in-patients-with-chagas-heart-disease
#6
Catherine Masiel Merejo Peña, Michel Silva Reis, Basílio de Bragança Pereira, Emília Matos do Nascimento, Roberto Coury Pedrosa
BACKGROUND: It has been difficult to prove that the "catecholamine-induced cardiomyopathy" contributes to the mechanism of sudden cardiac death in Chagas heart disease. Also, it is almost impossible to rule out the possibility that is not involved in the process. More importantly, the vagal-cholinergic pathway in the ventricle plays a direct role in the prevention of the initiation of complex ventricular arrhythmias, including non-sustained ventricular tachycardia, ventricular fibrillation responsible for sudden death...
January 5, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29315256/a-novel-attitude-determination-system-aided-by-polarization-sensor
#7
Wei Zhi, Jinkui Chu, Jinshan Li, Yinlong Wang
This paper aims to develop a novel attitude determination system aided by polarization sensor. An improved heading angle function is derived using the perpendicular relationship between directions of E-vector of linearly polarized light and solar vector in the atmospheric polarization distribution model. The Extended Kalman filter (EKF) with quaternion differential equation as a dynamic model is applied to fuse the data from sensors. The covariance functions of filter process and measurement noises are deduced in detail...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29303373/cardiac-autonomic-function-and-reactivity-tests-in-physically-active-subjects-with-moderately-severe-copd
#8
Jibril Mohammed, Eric Derom, Tine De Backer, Inge De Wandele, Patrick Calders
Patients with chronic obstructive pulmonary disease (COPD) show impairments in the autonomic nervous systems (ANS) function, which is responsible for cardiac autonomic regulation. This study assessed the autonomic function and cardio-vagal reactivity in conveniently sampled subjects with COPD participating in a pulmonary rehabilitation (PR) program. Twenty-six subjects with COPD and 22 age and gender matched control subjects were evaluated. R-R intervals were collected at rest in supine position. Thereafter, resting autonomic function parameters comprising linear and nonlinear analyses of heart rate variability (HRV) and baroreceptor sensitivity (BRS) were calculated...
January 5, 2018: COPD
https://www.readbyqxmd.com/read/29298212/electrophysiology-of-cranial-nerve-testing-cranial-nerves-ix-and-x
#9
Alberto R M Martinez, Melina P Martins, Ana Lucila Moreira, Carlos R Martins, Paulo A T Kimaid, Marcondes C França
The cranial nerves IX and X emerge from medulla oblongata and have motor, sensory, and parasympathetic functions. Some of these are amenable to neurophysiological assessment. It is often hard to separate the individual contribution of each nerve; in fact, some of the techniques are indeed a composite functional measure of both nerves. The main methods are the evaluation of the swallowing function (combined IX and X), laryngeal electromyogram (predominant motor vagal function), and heart rate variability (predominant parasympathetic vagal function)...
January 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29289531/epileptic-seizures-are-reduced-by-autonomic-biofeedback-therapy-through-enhancement-of-fronto-limbic-connectivity-a-controlled-trial-and-neuroimaging-study
#10
Yoko Nagai, Julia Aram, Matthias Koepp, Louis Lemieux, Marco Mula, Hugo Critchley, Sanjay Sisodiya, Mara Cercignani
BACKGROUND: Thirty-percent of patients with epilepsy are drug-resistant, and might benefit from effective noninvasive therapeutic interventions. Evidence is accumulating on the efficacy of autonomic biofeedback therapy using galvanic skin response (GSR; an index of sympathetic arousal) in treating epileptic seizures. This study aimed to extend previous controlled clinical trials of autonomic biofeedback therapy with a larger homogeneous sample of patients with temporal lobe epilepsy. In addition, we used neuroimaging to characterize neural mechanisms of change in seizure frequency following the therapy...
December 13, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29289186/picosecond-precision-multichannel-autonomous-time-and-frequency-counter
#11
R Szplet, P Kwiatkowski, K Różyc, Z Jachna, T Sondej
This paper presents the design, implementation, and test results of a multichannel time interval and frequency counter developed as a desktop instrument. The counter contains four main functional modules for (1) performing precise measurements, (2) controlling and fast data processing, (3) low-noise power suppling, and (4) supplying a stable reference clock (optional rubidium standard). A fundamental for the counter, the time interval measurement is based on time stamping combined with a period counting and in-period two-stage time interpolation that allows us to achieve wide measurement range (above 1 h), high precision (even better than 4...
December 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29288564/luteinizing-hormone-and-insulin-resistance-in-menopausal-patients-with-adrenal-incidentalomas-the-cause-effect-relationship
#12
Ljiljana V Marina, Miomira Ivović, Milina Tančić-Gajić, Zorana Arizanović, Dragana Raković, Jelena Milin-Lazović, Aleksandra Kendereški, Dragan Micić, Svetlana Vujović
OBJECTIVE: A high prevalence of insulin resistance (IR) has proven to manifest in patients with adrenal incidentalomas (AI). It has been demonstrated that an increase in IR is related to the size of tumourous masses; additionally, luteinizing hormone (LH) dependent adrenal pathologies are well documented in patients with LH responsive adrenal tumours occurring under conditions of physiologically elevated LH. We hypothesized that an association between LH and insulin might play a role in adrenal tumourigenesis and steroidogenesis...
December 30, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29281319/autonomy-support-need-satisfaction-and-motivation-for-support-among-adults-with-intellectual-disability-testing-a-self-determination-theory-model
#13
Noud Frielink, Carlo Schuengel, Petri J C M Embregts
The tenets of self-determination theory as applied to support were tested with structural equation modelling for 186 people with ID with a mild to borderline level of functioning. The results showed that (a) perceived autonomy support was positively associated with autonomous motivation and with satisfaction of need for autonomy, relatedness, and competence; (b) autonomous motivation and need satisfaction were associated with higher psychological well-being; (c) autonomous motivation and need satisfaction statistically mediated the association between autonomy support and well-being; and (d) satisfaction of need for autonomy and relatedness was negatively associated with controlled motivation, whereas satisfaction of need for relatedness was positively associated with autonomous motivation...
January 2018: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/29280995/the-autonomous-flowering-time-pathway-pleiotropically-regulates-seed-germination-in-arabidopsis-thaliana
#14
Gabriela A Auge, Logan K Blair, Aleena Karediya, Kathleen Donohue
Background and Aims: Two critical developmental transitions in plants are seed germination and flowering, and the timing of these transitions has strong fitness consequences. How genetically independent the regulation of these transitions is can influence the expression of life cycles. Method: This study tested whether genes in the autonomous flowering-time pathway pleiotropically regulate flowering time and seed germination in the genetic model Arabidopsis thaliana, and tested whether the interactions among those genes are concordant between flowering and germination stages...
December 21, 2017: Annals of Botany
https://www.readbyqxmd.com/read/29275061/deterioration-of-chronotropic-responses-and-heart-rate-recovery-indices-in-men-with-erectile-dysfunction
#15
Faruk Kucukdurmaz, Gurkan Acar, Sefa Resim
INTRODUCTION: Erectile dysfunction (ED) and cardiovascular (CV) diseases share common risk factors and ED has been accepted as an early manifestation of CV disease. Exercise stress testing (EST) is used to evaluate CV functions in men with ED. Low exercise workload, a slower heart rate recovery (HRR) after exercise, and inability to increase heart rate during EST (chronotropic incompetence) are independent negative predictors of adverse CV outcomes. AIM: To assess the association among EST parameters, ED, and testosterone levels...
December 20, 2017: Sexual Medicine
https://www.readbyqxmd.com/read/29259347/administration-of-assessment-instruments-during-the-first-rehabilitation-of-patients-with-spinal-cord-injury-a-retrospective-chart-analysis
#16
Patricia Lampart, Armin Gemperli, Michael Baumberger, Ines Bersch, Birgit Prodinger, Klaus Schmitt, Anke Scheel-Sailer
STUDY DESIGN: Retrospective chart analysis. OBJECTIVES: To examine which professionals administered which assessment instruments in which patient in clinical practice during first rehabilitation after newly acquired spinal cord injury (SCI) and the differences in the frequencies of different assessments between patient groups. SETTING: Specialized SCI acute care and rehabilitation clinic. METHODS: Patients after SCI, aged 18 years and above, admitted for first rehabilitation between December 2014 and December 2015 were analyzed...
December 20, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29249575/combined-cardiovascular-and-sweating-autonomic-testing-to-differentiate-multiple-system-atrophy-from-parkinson-s-disease
#17
Anne Pavy-LeTraon, Christine Brefel-Courbon, Julia Dupouy, Fabienne Ory-Magne, Olivier Rascol, Jean-Michel Senard
OBJECTIVES: It can be difficult to differentiate multiple system atrophy (MSA) with predominant parkinsonism (MSA-P), a very disabling but rare disease, from Parkinson's disease (PD). Autonomic dysfunction, particularly cardiovascular autonomic neuropathy (CAN), is classically more pronounced in MSA. We investigated whether testing for CAN combined with sweat function assessment was helpful to differentiate patients with MSA from those with PD. METHODS: In this retrospective study, 62 patients with MSA-P and 96 with PD, comparable in age, BMI and sex ratio with disease duration of 4...
December 14, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29248204/intestinal-permeability-and-m%C3%A3-ni%C3%A3-re-s-disease
#18
F Di Berardino, D Zanetti, E Ciusani, C Caccia, V Leoni, U De Grazia, E Filipponi, L Elli
PURPOSE: Ménière disease (MD) is a multifactorial chronic disabling condition characterized by episodic vertigo, ear fullness, and hearing loss. MD patients often complain of aspecific gastrointestinal symptoms associated with autonomic dysregulation, frequently outweighed by the otological manifestations. Dietary modifications have been reported to improve the typical MD symptoms in some cases. Our purpose was to test the urinary levels of lactulose and mannitol (double sugar test) and the fecal calprotectin, both markers of altered intestinal permeability, in subjects with definite MD in an active and inactive stage...
December 5, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29242088/voluntarily-induced-vomiting-a-yoga-technique-to-enhance-pulmonary-functions-in-healthy-humans
#19
Ragavendrasamy Balakrishnan, Ramesh Mavathur Nanjundaiah, Nandi Krishnamurthy Manjunath
Vomiting is a complex autonomic reflex orchestrated by several neurological centres in the brain. Vagus, the cranial nerve plays a key role in regulation of vomiting. Kunjal Kriya (Voluntarily Induced Vomiting), is a yogic cleansing technique which involves voluntarily inducing vomiting after drinking saline water (5%) on empty stomach. This study was designed with an objective to understand the effect of voluntary induced vomiting (ViV) on pulmonary functions in experienced practitioners and novices and derive its possible therapeutic applications...
December 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29241836/opposite-effects-of-stress-on-pain-modulation-depend-on-the-magnitude-of-individual-stress-response
#20
Nirit Geva, Ruth Defrin
The effect of acute stress on pain threshold and intolerance threshold are reported as producing either hypoalgesia or hyperalgesia. Yet, the contribution of individual stress reactivity in this respect has not been established. The aim was to test two pain modulation paradigms under acute stress manipulation, here for the first time, in order to study whether stress differentially affects pain modulation, and whether the effect is related to individual stress response. Participants were 31 healthy subjects...
December 11, 2017: Journal of Pain: Official Journal of the American Pain Society
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