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Post operative mortality silent mi

Jiayan Lei, Fengxi Zhu, Yi Zhang, Lixiao Duan, Han Lei, Wei Huang
OBJECTIVE: A high mortality rate occurs with silent myocardial infarction (MI), particularly in aging and diabetic populations due to defects in the transient receptor potential vanilloid (TRPV1)-positive sensory nerve function. We have previously shown that TRPV1 deficiency markedly enhances post-MI inflammation and remodeling. However, the mechanisms remain unknown. The objective of this study was to clarify whether calcitonin gene-related peptide (CGRP) release was associated with the protective role of TRPV1 against postmyocardial inflammation and apoptosis...
2016: Cardiology
R B Grobben, J E P Vrijenhoek, H M Nathoe, H M Den Ruijter, J A R van Waes, L M Peelen, W A van Klei, G J de Borst
OBJECTIVE: Myocardial infarction (MI) is a frequent complication of carotid endarterectomy (CEA), yet most events are silent. Routine post-operative monitoring of cardiac troponin was implemented to facilitate timely recognition of MI and stratify high risk patients. The aim was to evaluate the incidence of troponin elevation after CEA and its association with adverse cardiovascular events. METHODS: This analysis included patients ≥60 years old who underwent CEA, whose troponin-I levels were routinely monitored post-operatively and were included in a cohort study that assessed clinical outcomes...
April 2016: European Journal of Vascular and Endovascular Surgery
C Michael Gibson, Lauren N Ciaglo, Matthew C Southard, Shaun Takao, Caitlin Harrigan, Jason Lewis, Jason Filopei, Michelle Lew, Sabina A Murphy, Jacqueline Buros
Silent ischemia, the most common expression of atherosclerotic heart disease, affects approximately 30-50% of patients during their activities of daily living. The present review provides a comprehensive and practical summary of current knowledge on perioperative myocardial ischemia through MEDLINE searches up to June 2005, using keywords including "silent ischemia," "transient ischemia," and "Holter monitoring." Holter monitoring (i.e., continuous ambulatory ST-segment monitoring) is an effective tool for assessing the frequency and duration of silent transient myocardial ischemia, particularly in patients who are post-acute myocardial infarction (MI), those with acute coronary syndromes (ACS), and in patients in the acute post-operative period...
April 2007: Journal of Thrombosis and Thrombolysis
K Kyösola, D Chambers, S Canković-Darracott, M V Braimbridge
The effectiveness of St. Thomas' Hospital cardioplegia for myocardial preservation during prolonged aortic cross-clamping was analyzed in a clinical series of 100 consecutive cardiac surgical patients identified as having aortic cross-clamp times greater than 120 minutes. Hospital mortality from all causes was 8%, but only one of these 8 patients succumbed from immediate primary failure of the myocardial preservation protocol. Severe but reversible low cardiac output syndrome occurred in 5 patients, and in 4 of them there had obviously been a primary failure in cardiac protection...
1985: Annales Chirurgiae et Gynaecologiae
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