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Post operative morbidity myocardial infarction

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https://www.readbyqxmd.com/read/27807846/borderline-operability-in-hepatectomy-patients-is-associated-with-higher-rates-of-failure-to-rescue-after-severe-complications
#1
Bradford J Kim, Ching-Wei D Tzeng, Amanda B Cooper, Jean-Nicolas Vauthey, Thomas A Aloia
BACKGROUND/OBJECTIVE: To understand the influence of age and comorbidities, this study analyzed the incidence and risk factors for post-hepatectomy morbidity/mortality in patients with "borderline" (BL) operability, defined by the preoperative factors: age ≥75 years, dependent function, lung disease, ascites/varices, myocardial infarction, stroke, steroids, weight loss >10%, and/or sepsis. METHODS: All elective hepatectomies were identified in the 2005-2013 ACS-NSQIP database...
November 3, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27600185/myocardial-ischemia-reperfusion-impairs-neurogenesis-and-hippocampal-dependent-learning-and-memory
#2
Kirsten S Evonuk, Sumanth D Prabhu, Martin E Young, Tara M DeSilva
The incidence of cognitive impairment in cardiovascular disease (CVD) patients has increased, adversely impacting quality of life and imposing a significant economic burden. Brain imaging of CVD patients has detected changes in the hippocampus, a brain region critical for normal learning and memory. However, it is not clear whether adverse cardiac events or other associated co-morbidities impair cognition. Here, using a murine model of acute myocardial ischemia/reperfusion (I/R), where the coronary artery was occluded for 30 minutes followed by reperfusion, we tested the hypothesis that acute myocardial infarction triggers impairment in cognitive function...
September 3, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27527344/a-multicentre-randomised-controlled-trial-of-transfusion-indication-threshold-reduction-on-transfusion-rates-morbidity-and-health-care-resource-use-following-cardiac-surgery-titre2
#3
Barnaby C Reeves, Katie Pike, Chris A Rogers, Rachel Cm Brierley, Elizabeth A Stokes, Sarah Wordsworth, Rachel L Nash, Alice Miles, Andrew D Mumford, Alan Cohen, Gianni D Angelini, Gavin J Murphy
BACKGROUND: Uncertainty about optimal red blood cell transfusion thresholds in cardiac surgery is reflected in widely varying transfusion rates between surgeons and cardiac centres. OBJECTIVE: To test the hypothesis that a restrictive compared with a liberal threshold for red blood cell transfusion after cardiac surgery reduces post-operative morbidity and health-care costs. DESIGN: Multicentre, parallel randomised controlled trial and within-trial cost-utility analysis from a UK NHS and Personal Social Services perspective...
August 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27118140/influence-of-body-mass-index-on-outcomes-after-minimal-access-aortic-valve-replacement-through-a-j-shaped-partial-upper-sternotomy
#4
Metesh Acharya, Leanne Harling, Marco Moscarelli, Hutan Ashrafian, Thanos Athanasiou, Roberto Casula
BACKGROUND: Minimal-access aortic valve replacement (MAAVR) may reduce post-operative blood loss and transfusion requirements, decrease post-operative pain, shorten length stay and enhance cosmesis. This may be particularly advantageous in overweight/obese patients, who are at increased risk of post-operative complications. Obese patients are however often denied MAAVR due to the perceived technical procedural difficulty. This retrospective analysis sought to determine the effect of BMI on post-operative outcomes in patients undergoing MAAVR...
2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/26994519/pre-operative-labs-wasted-dollars-or-predictors-of-post-operative-cardiac-and-septic-events-in-orthopaedic-trauma-patients
#5
Nikita Lakomkin, Vasanth Sathiyakumar, Ashley C Dodd, A Alex Jahangir, Paul S Whiting, William T Obremskey, Manish K Sethi
PURPOSE: As US healthcare expenditures continue to rise, there is significant pressure to reduce the cost of inpatient medical services. Studies have estimated that over 70% of routine labs may not yield clinical benefits while adding over $300 in costs per day for every inpatient. Although orthopaedic trauma patients tend to have longer inpatient stays and hip fractures have been associated with significant morbidity, there is a dearth of data examining pre-operative labs in predicting post-operative adverse events in these populations...
June 2016: Injury
https://www.readbyqxmd.com/read/26900455/comparison-of-open-gastrostomy-tube-to-percutaneous-endoscopic-gastrostomy-tube-in-lung-transplant-patients
#6
Sharven Taghavi, Vishnu Ambur, Senthil Jayarajan, John Gaughan, Yoshiya Toyoda, Elizabeth Dauer, Lars Ola Sjoholm, Abhijit Pathak, Thomas Santora, Amy J Goldberg
INTRODUCTION: Lung transplant patients require a high degree of immunosuppression, which can impair wound healing when surgical procedures are required. We hypothesized that because of impaired healing, lung transplant patients requiring gastrostomy tubes would have better outcomes with open gastrostomy tube (OGT) as compared to percutaneous endoscopic gastrostomy tube (PEG). METHODS: The National Inpatient Sample (NIS) Database (2005-2010) was queried for all lung transplant recipients requiring OGT or PEG...
February 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/26853917/the-varying-effects-of-obesity-and-morbid-obesity-on-outcomes-following-cardiac-transplantation
#7
J Nagendran, M D Moore, C M Norris, A Khani-Hanjani, M M Graham, D H Freed, J Nagendran
The purpose of this study was to compare the outcomes of patients undergoing cardiac transplantation stratified by body mass index (BMI, kg m(-)(2)). The Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease registry captured 220 cardiac transplantations in Alberta, Canada from January 2004 to April 2013. All recipients were stratified by BMI into five groups (BMI: <20, 20-24.9, 25-29.9, 30-<34.9 and ⩾35). Patient characteristics were analyzed by analysis of variance and χ(2) analyses...
April 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/26810343/anemia-increases-mortality-after-open-or-endovascular-treatment-in-patients-with-critical-limb-ischemia-a-retrospective-analysis
#8
COMPARATIVE STUDY
A Velescu, A Clará, M Cladellas, J Peñafiel, E Mateos, S Ibañez, M Mellado
OBJECTIVES: Pre-operative anemia has been associated with increased post-operative morbidity and mortality in elective cardiac surgery, but its association with post-operative mortality after open or endovascular surgery for critical limb ischemia (CLI) is not well established. The aim of this study was to evaluate the relationship between pre-operative anemia and mortality in surgery for CLI. MATERIALS AND METHODS: A retrospective study of 403 consecutive patients (mean age = 73; 73% male) undergoing open (n = 191, 47%) or endovascular (n = 212, 53%) surgery for CLI between 2005 and 2013 was performed...
April 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/26790974/carotid-endarterectomy-for-critical-stenosis-prior-to-cardiac-surgery-should-it-be-done-a-retrospective-cohort-study
#9
Mohammed Ashrafi, Stephen Ball, Abid Ali, Iraj Zeynali, Vittorio Perricone
INTRODUCTION: Stroke remains a major cause of morbidity and mortality after cardiac surgery affecting 2% of patients. Extra-cranial carotid artery disease has been implicated in the aetiology of post cardiac surgery stroke. The aim of the study was to evaluate and compare the morbidity and mortality in patients undergoing cardiac surgery with or without staged carotid endarterectomy (CEA) in a tertiary referral centre. METHODS: A 5 year retrospective study was performed...
February 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/26612068/feasibility-and-safety-of-continuous-retrograde-administration-of-del-nido-cardioplegia-a-case-series
#10
Marc Najjar, Isaac George, Hirokazu Akashi, Takashi Nishimura, Halit Yerebakan, Linda Mongero, James Beck, Stephen C Hill, Hiroo Takayama, Mathew R Williams
BACKGROUND: Del Nido (DN) cardioplegia, a calcium-free, hyperkalemic solution containing lidocaine and magnesium has been developed to help reduce intracellular calcium influx and the resulting myocyte damage in the immediate postischemic period following cardiac arrest. DN cardioplegia has been used for pediatric cardiac surgery but its use in complex reoperative surgery has not been studied. We specifically report the outcomes of patients undergoing reoperative cardiac surgery after previous coronary artery bypass grafting with a patent internal mammary artery (IMA)...
November 26, 2015: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/26382910/treating-peritoneal-mesothelioma-with-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-a-case-series-and-review-of-the-literature
#11
Konstantinos Stamou, Dimitrios Tsamis, Nikolaos Pallas, Evangelia Samanta, Nikolaos Courcoutsakis, Panos Prassopoulos, Antonios-Apostolos Tentes
BACKGROUND: Encouraging results on survival of patients with malignant peritoneal mesothelioma have been shown with the use of cytoreductive surgery and perioperative intraperitoneal chemotherapy. This study explores the impact of aggressive surgical treatment on overall survival of peritoneal mesothelioma. METHODS: This is a retrospective analysis of prospectively collected clinical data of all patients with diagnosis of malignant peritoneal mesothelioma treated in a designated referral centre in Greece...
2015: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/26381509/identification-of-intrastent-pathology-associated-with-late-stent-thrombosis-using-optical-coherence-tomography
#12
Christopher R Jones, Sameer J Khandhar, Mohun Ramratnam, Suresh R Mulukutla, Oscar C Marroquin, Andrew D Althouse, Anjali Rao, Koji Kato, Ik-Kyung Jang, Catalin Toma
OBJECTIVE: To better characterize intrastent pathology using optical coherence tomography (OCT) in patients presenting with late and very late stent thrombosis (LST/VLST). BACKGROUND: The contribution of specific intrastent pathologies to the development of LST/VLST is not well understood. METHODS: In this single-center, retrospective, observational study of 796 consecutive patients treated for ST-segment elevation myocardial infarction (STEMI) with primary PCI we identified 57 patients (7...
October 2015: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/26324081/low-mortality-and-morbidity-after-endovascular-repair-of-ruptured-aortic-aneurysm
#13
Stevo Duvnjak, Tomas Balezantis, Jes S Lindholt
INTRODUCTION: The objective of this study was to describe the implementation and to evaluate the short-term outcome of the first Danish experience with endovascular repair of ruptured abdominal aortic aneurysm (RAAA). METHODS: This was a historical prospective cohort study including all patients at Odense University Hospital, Denmark, treated for RAAA and/or iliac artery aneurysm rupture from 1 October 2012 to December 2013. RESULTS: A total of 53 patients were treated due to RAAA or iliac aneurysms at our institution in this period...
September 2015: Danish Medical Journal
https://www.readbyqxmd.com/read/26194916/risk-factors-for-adverse-cardiac-events-in-hip-fracture-patients-an-analysis-of-nsqip-data
#14
Vasanth Sathiyakumar, Frank R Avilucea, Paul S Whiting, A Alex Jahangir, Hassan R Mir, William T Obremskey, Manish K Sethi
PURPOSE: Cardiovascular complications constitute morbidity and mortality for hip fracture patients. Relatively little data exist exploring risk factors for post-operative complications. Using the American College of Surgeons National Surgical Quality Improvement (ACS-NSQIP) database, we identified significant risk factors associated with adverse cardiac events in hip fracture patients and provide recommendations for practising orthopaedists. METHODS: A cohort of 27,441 patients with hip fractures from 2006 to 2013 was identified using Current Procedural Terminology codes...
March 2016: International Orthopaedics
https://www.readbyqxmd.com/read/26047812/embolization-of-the-first-diagonal-branch-of-the-left-anterior-descending-coronary-artery-as-a-porcine-model-of-chronic-trans-mural-myocardial-infarction
#15
Derek W Hanes, Maelene L Wong, C W Jenny Chang, Sterling Humphrey, J Kevin Grayson, Walter D Boyd, Leigh G Griffiths
BACKGROUND: Although the incidence of acute death related to coronary artery disease has decreased with the advent of new interventional therapies, myocardial infarction remains one of the leading causes of death in the US. Current animal models developed to replicate this phenomenon have been associated with unacceptably high morbidity and mortality. A new model utilizing the first diagonal branch of the left anterior descending artery (D1-LAD) was developed to provide a clinically relevant lesion, while attempting to minimize the incidence of adverse complications associated with infarct creation...
June 6, 2015: Journal of Translational Medicine
https://www.readbyqxmd.com/read/25984239/gene-expression-profiling-reveals-potential-prognostic-biomarkers-associated-with-the-progression-of-heart-failure
#16
Agata Maciejak, Marek Kiliszek, Marcin Michalak, Dorota Tulacz, Grzegorz Opolski, Krzysztof Matlak, Slawomir Dobrzycki, Agnieszka Segiet, Monika Gora, Beata Burzynska
BACKGROUND: Heart failure (HF) is the most common cause of morbidity and mortality in developed countries. Here, we identify biologically relevant transcripts that are significantly altered in the early phase of myocardial infarction and are associated with the development of post-myocardial infarction HF. METHODS: We collected peripheral blood samples from patients with ST-segment elevation myocardial infarction (STEMI): n = 111 and n = 41 patients from the study and validation groups, respectively...
2015: Genome Medicine
https://www.readbyqxmd.com/read/25935413/risk-factors-and-outcome-analysis-after-surgical-management-of-ventricular-septal-rupture-complicating-acute-myocardial-infarction-a-retrospective-analysis
#17
Shih-Ming Huang, Shu-Chien Huang, Chih-Hsien Wang, I-Hui Wu, Nai-Hsin Chi, Hsi-Yu Yu, Ron-Bin Hsu, Chung-I Chang, Shoei-Shen Wang, Yih-Sharng Chen
BACKGROUND: Ventricular septal rupture (VSR) is an uncommon but well-recognized mechanical complication of acute myocardial infarction (AMI). The outcome of VSR remains poor even in the era of reperfusion therapy. We reviewed our experience with surgical repair of post-infarction VSR and analyzed outcomes in an attempt to identify prognostic factors. METHODS: From October 1995 to December 2013, data from 47 consecutive patients (mean age, 68 ± 9.5 years) with post-infarction VSR who underwent surgical repair at our institute were retrospectively reviewed...
2015: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/25897628/red-blood-cell-transfusion-for-people-undergoing-hip-fracture-surgery
#18
REVIEW
Susan J Brunskill, Sarah L Millette, Ali Shokoohi, E C Pulford, Carolyn Doree, Michael F Murphy, Simon Stanworth
BACKGROUND: The incidence of hip fracture is increasing and it is more common with increasing age. Surgery is used for almost all hip fractures. Blood loss occurs as a consequence of both the fracture and the surgery and thus red blood cell transfusion is frequently used. However, red blood cell transfusion is not without risks. Therefore, it is important to identify the evidence for the effective and safe use of red blood cell transfusion in people with hip fracture. OBJECTIVES: To assess the effects (benefits and harms) of red blood cell transfusion in people undergoing surgery for hip fracture...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/25671927/early-outcome-of-coronary-artery-bypass-grafting-in-patients-with-unstable-angina
#19
Iftikhar Paras, Allah Bakhsh, Ghulam Hussain, Yasir Khan, Muhammad Moeen
BACKGROUND: Unstable angina is a common cause of admission to hospitals. There is conflicting evidence on the need and success of urgent coronary revascularization in such cases. This study was conducted to evaluate the early post-operative morbidity and mortality of Coronary Artery Bypass Grafting (CABG) in patients with unstable angina. METHODS: This cross sectional descriptive study was conducted at Choudry Pervaiz Elahi Institute of Cardiology, Multan. The data of the all the patients who had undergone CABG for unstable angina, between February 2009 and March 2010, was collected and analysed...
July 2014: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/25414823/transient-post-operative-atrial-fibrillation-predicts-short-and-long-term-adverse-events-following-cabg
#20
Femi Philip, Matthew Becker, John Galla, Eugene Blackstone, Samir R Kapadia
OBJECTIVE: To assess the relationship between the development of transient post-operative atrial fibrillation (TPOAF) following coronary artery bypass graft (CABG) surgery and risk of long-term mortality. BACKGROUND: Atrial fibrillation (AF) following CABG is common and associated with increased morbidity and mortality in the perioperative period. However the impact of TPOAF and its management on long-term morbidity and mortality in patients undergoing first time, isolated CABG surgery remains unclear...
October 2014: Cardiovascular Diagnosis and Therapy
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