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Tinnitus supplement

Felice Scasso, Andrea Elio Sprio, Luciano Canobbio, Chiara Scanarotti, Giorgio Manini, Giovanni Nicolao Berta, Anna Maria Bassi
Oxidative stress exerts major role in the pathogenesis of side effects of many antineoplastic drugs, including ototoxicity of cisplatin. In particular, increased levels of reactive oxygen species (ROS) represent one of the molecular mechanisms underlying the apoptosis of different types of hearing cells. Antioxidants and ROS scavengers may thus represent potential therapeutic options to prevent platinum-associated ototoxicity. The aim of this preliminary case-control study was to explore the efficacy of a dietary antioxidant supplement, in order to hamper the occurrences of ototoxicity in patients undergoing cisplatin chemotherapy...
February 2017: Heliyon
Omid Moshtaghi, Yarah M Haidar, Ronald Sahyouni, Ramin Rajaii, Afsheen Moshtaghi, Amin Mahmoodi, Yaser Ghavami, Harrison W Lin, Hamid R Djalilian
INTRODUCTION: Physicians in the ambulatory setting face challenges in adequately educating patients in a brief office encounter. OBJECTIVE: To evaluate the efficacy of an iPad-based interactive educational module (iBook) in various otologic pathologies. METHODS: Patients presenting with symptoms of tinnitus, dizziness, hearing loss, or cochlear implant evaluation were included. In total, 44 patients received the iBook and 22 patients served as controls...
March 2017: American Journal of Otolaryngology
C G Le Prell, A Fulbright, C Spankovich, S K Griffiths, E Lobarinas, K C M Campbell, P J Antonelli, G E Green, K Guire, J M Miller
This study examined potential prevention of music-induced temporary threshold shift (TTS) in normal-hearing participants. A dietary supplement composed of β-carotene, vitamins C and E, and magnesium was assessed using a randomized, placebo-controlled, double-blind study design. Dosing began 3 days prior to the music exposure with the final dose consumed approximately 30-min pre-exposure. There were no group differences in post-exposure TTS or music-induced decreases in distortion product otoacoustic emission (DPOAE) amplitude...
May 2016: Audiology and Neurotology. Extra
Osmar C Person, Maria Es Puga, Edina Mk da Silva, Maria R Torloni
BACKGROUND: Tinnitus is the perception of sound without external acoustic stimuli. Patients with severe tinnitus may have physical and psychological complaints and their tinnitus can cause deterioration in their quality of life. At present no specific therapy for tinnitus has been found to be satisfactory in all patients. In recent decades, a number of reports have suggested that oral zinc supplementation may be effective in the management of tinnitus. Since zinc has a role in cochlear physiology and in the synapses of the auditory system, there is a plausible mechanism of action for this treatment...
November 23, 2016: Cochrane Database of Systematic Reviews
Beau B Bruce, Kathleen B Digre, Michael P McDermott, Eleanor B Schron, Michael Wall
OBJECTIVE: To examine the changes in vision-specific and overall health-related quality of life (QOL) at 6 months in participants with idiopathic intracranial hypertension (IIH) and mild visual loss enrolled in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) and to determine the signs and symptoms of IIH that mediate the effect of acetazolamide on QOL. METHODS: We assessed QOL using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25), the 10-Item NEI-VFQ-25 Neuro-Ophthalmic Supplement, and the 36-Item Short Form Health Survey (SF-36)...
November 1, 2016: Neurology
Claudia Coelho, Richard Tyler, Haihong Ji, Eveling Rojas-Roncancio, Shelley Witt, Pan Tao, Hyung-Jin Jun, Tang Chuan Wang, Marlan R Hansen, Bruce J Gantz
PURPOSE: We surveyed the benefit of dietary supplements to treat tinnitus and reported adverse effects. METHOD: A website was created for people with tinnitus to complete a variety of questions. RESULTS: The 1,788 subjects who responded to questionnaires came from 53 different countries; 413 (23.1%) reported taking supplements. No effect on tinnitus was reported in 70.7%, improvement in 19.0%, and worsening in 10.3%. Adverse effects were reported in 6% (n = 36), including bleeding, diarrhea, headache, and others...
September 1, 2016: American Journal of Audiology
Kate Greenwell, Magdalena Sereda, Neil Coulson, Amr El Refaie, Derek J Hoare
OBJECTIVE: Self-help interventions are followed by people independently with minimal or no therapist contact. This review aims to assess the effectiveness of self-help interventions for adults with chronic tinnitus and systematically identify the self-help techniques used. DESIGN: Systematic review and application of health psychology taxonomies. Electronic database searches were conducted, supplemented by citation searching and hand-searching of key journals. Prospective controlled trials, which used measures of tinnitus distress, functional management, anxiety, depression, and quality of life, were included...
July 2016: International Journal of Audiology
Richard J Harvey
No abstract text is available yet for this article.
July 2015: Journal of Laryngology and Otology
Michael D Seidman, Syed F Ahsan
PURPOSE OF REVIEW: The purpose of this review is to describe our experience with management of chronic tinnitus and to review the recent literature on the best treatment options available for treating patients who are troubled by their tinnitus. In addition, we want to highlight our experience and approach to this very common problem. RECENT FINDINGS: Treatment options for patients are based on the severity of the tinnitus and any associated problems. The use of nutritional supplements has a place in the treatment of mild-to-moderate tinnitus...
October 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
Björn Spittau, Diego San Millán, Saad El-Sherifi, Claudia Hader, Tejinder Pal Singh, Edith Motschall, Werner Vach, Horst Urbach, Stephan Meckel
Dural arteriovenous fistulas (DAVFs) of the hypoglossal canal (HCDAVFs) are rare and display a complex angiographic anatomy. Hitherto, they have been referred to as various entities (for example, "marginal sinus DAVFs") solely described in case reports or small series. In this in-depth review of HCDAVF, the authors describe clinical and imaging findings, as well as treatment strategies and subsequent outcomes, based on a systematic literature review supplemented by their own cases (120 cases total). Further, the involved craniocervical venous anatomy with variable venous anastomoses is summarized...
April 2015: Journal of Neurosurgery
David E Tunkel, Carol A Bauer, Gordon H Sun, Richard M Rosenfeld, Sujana S Chandrasekhar, Eugene R Cunningham, Sanford M Archer, Brian W Blakley, John M Carter, Evelyn C Granieri, James A Henry, Deena Hollingsworth, Fawad A Khan, Scott Mitchell, Ashkan Monfared, Craig W Newman, Folashade S Omole, C Douglas Phillips, Shannon K Robinson, Malcolm B Taw, Richard S Tyler, Richard Waguespack, Elizabeth J Whamond
The American Academy of Otolaryngology--Head and Neck Surgery Foundation (AAO-HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Tinnitus. To assist in implementing the guideline recommendations, this article summarizes the rationale, purpose, and key action statements. The 13 recommendations developed address the evaluation of patients with tinnitus, including selection and timing of diagnostic testing and specialty referral to identify potential underlying treatable pathology...
October 2014: Otolaryngology—Head and Neck Surgery
David E Tunkel, Carol A Bauer, Gordon H Sun, Richard M Rosenfeld, Sujana S Chandrasekhar, Eugene R Cunningham, Sanford M Archer, Brian W Blakley, John M Carter, Evelyn C Granieri, James A Henry, Deena Hollingsworth, Fawad A Khan, Scott Mitchell, Ashkan Monfared, Craig W Newman, Folashade S Omole, C Douglas Phillips, Shannon K Robinson, Malcolm B Taw, Richard S Tyler, Richard Waguespack, Elizabeth J Whamond
OBJECTIVE: Tinnitus is the perception of sound without an external source. More than 50 million people in the United States have reported experiencing tinnitus, resulting in an estimated prevalence of 10% to 15% in adults. Despite the high prevalence of tinnitus and its potential significant effect on quality of life, there are no evidence-based, multidisciplinary clinical practice guidelines to assist clinicians with management. The focus of this guideline is on tinnitus that is both bothersome and persistent (lasting 6 months or longer), which often negatively affects the patient's quality of life...
October 2014: Otolaryngology—Head and Neck Surgery
Paola Staffa, Jacopo Cambi, Chiara Mezzedimi, Desiderio Passali, Luisa Bellussi
A potential consequence of exposure to noise is a temporary reduction in auditory sensitivity known as temporary threshold shift (TTS), which mainly depends on the intensity and duration of exposure to the noise. Recovery time is related to the amount of initial hearing loss, and the most recovery takes place during the first 15 min following exposure. This study evaluated the efficacy in otoprotection against noise-induced hearing loss of an orally administrated food supplement containing coenzyme Q 10 -Ter...
September 2014: Noise & Health
R Luzzi, G Belcaro, S Hu, M Dugall, M Hosoi, M Cacchio, E Ippolito, M Corsi
AIM: The aim of this supplement registry was to evaluate the efficacy of the Pycnogenol® in improving cochlear flow and symptoms in a 6-month follow-up for patients with Meniere's disease (MD), tinnitus and cochlear hypoperfusion. METHODS: Main signs/symptoms were considered: Spontaneous vertigo, positional vertigo, hearing loss, tinnitus, pressure in the ear, unsteady gait, associated clinical problems, alterations in daily life. All subjects were managed with the best available management (BM); one group used the supplement Pycnogenol (150 mg/day)...
June 2014: Minerva Medica
Leah Merrick, Dima Youssef, Michelle Tanner, Alan N Peiris
Melatonin, a hormone produced by the pineal gland, may be a promising treatment option for tinnitus. The primary functions of this hormone are believed to be the initiation and maintenance of sleep because its secretions coincide with circadian rhythms. Some investigators have noted that melatonin may alleviate subjective symptoms of tinnitus. Moreover, melatonin may have properties protective against ototoxic drugs such as amikacin, gentamicin, or cancer therapeutic agents that are dose dependent. In vitro, melatonin has demonstrated antioxidative properties and it has been postulated that these antioxidative properties contribute to the alleviation of tinnitus...
June 2014: Southern Medical Journal
Ben Coomber, Joel I Berger, Victoria L Kowalkowski, Trevor M Shackleton, Alan R Palmer, Mark N Wallace
Animal models of tinnitus allow us to study the relationship between changes in neural activity and the tinnitus percept. Here, guinea pigs were subjected to unilateral noise trauma and tested behaviourally for tinnitus 8 weeks later. By comparing animals with tinnitus with those without, all of which were noise-exposed, we were able to identify changes unique to the tinnitus group. Three physiological markers known to change following noise exposure were examined: spontaneous firing rates (SFRs) and burst firing in the inferior colliculus (IC), evoked auditory brainstem responses (ABRs), and the number of neurons in the cochlear nucleus containing nitric oxide synthase (NOS)...
July 2014: European Journal of Neuroscience
Samantha C Herath, Phillippa Poole
BACKGROUND: There has been renewal of interest in the use of prophylactic antibiotics to reduce the frequency of exacerbations and improve quality of life in chronic obstructive pulmonary disease (COPD). OBJECTIVES: To determine whether or not regular treatment of COPD patients with prophylactic antibiotics reduces exacerbations or affects quality of life. SEARCH METHODS: We searched the Cochrane Airways Group Trials Register and bibliographies of relevant studies...
November 28, 2013: Cochrane Database of Systematic Reviews
G Berkiten, G Yildirim, I Topaloglu, H Ugras
OBJECTIVES: The aim of this study was to determine vitamin B12 levels in patients with non-pulsatile tinnitus and to assess the efficacy of replacement treatment in tinnitus and hearing in patients with vitamin B12 deficiency. MATERIALS AND METHODS: We assessed 100 patients (mean age, 43.87, SD 10.12; 62 females, 38 males) and 20 healthy volunteers (9 females, 11 males). Patients whose blood serum vitamin B12 levels were below 180 pg/mL were deemed to be vitamin B12-deficient...
2013: B-ENT
Matthias Unger
Ginkgo biloba leaf extracts (GLEs) are popular herbal remedies for the treatment of Alzheimer's dementia, tinnitus, vertigo and peripheral arterial disease. As GLEs are taken regularly by older people who are likely to also use multiple other drugs for the treatment of, e.g. hypertension, diabetes, rheumatism or heart failure, potential herb-drug interactions are of interest. Preclinical studies of high doses/concentrations of GLEs of varying quality and standardization hinted at both an inhibition and induction of metabolic enzymes and transporters...
August 2013: Drug Metabolism Reviews
Giray Aynali, Mustafa Ozkan, Ayşe Aynali, Betül Ceyhan, Hakan Armağan, Murat Yarıktaş, Mustafa Doğan
OBJECTIVES: This study aims to evaluate the serum levels of hemoglobin, vitamin B12 and folic acid in patients with recurrent minor aphthous stomatitis. PATIENTS AND METHODS: Between June 2010 and January 2012, a total of 112 patients including 57 with recurrent aphthous stomatitis (study group; 30 males 27 females; mean age 36.7±13.9 years; range 13 to 74 years) and 45 with chronic tinnitus patients without recurrent aphthous stomatitis (control group; 18 males 27 females; mean age 39...
May 2013: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
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