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MR neurography

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https://www.readbyqxmd.com/read/28710579/magnetic-resonance-neurography-current-perspectives-and-literature-review
#1
REVIEW
Avneesh Chhabra, Ananth J Madhuranthakam, Gustav Andreisek
Magnetic resonance neurography (also called MRN or MR neurography) refers to MR imaging dedicated to the peripheral nerves. It is a technique that enhances selective multiplanar visualisation of the peripheral nerve and pathology by encompassing a combination of two-dimensional, three-dimensional and diffusion imaging pulse sequences. Referring physicians who seek imaging techniques that can depict and diagnose peripheral nerve pathologies superior to conventional MR imaging are driving the demand for MRN. This article reviews the pathophysiology of peripheral nerves in common practice scenarios, technical considerations of MRN, current indications of MRN, normal and abnormal neuromuscular appearances, and imaging pitfalls...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28696850/advanced-mr-imaging-techniques-for-differentiation-of-neuropathic-arthropathy-and-osteomyelitis-in-the-diabetic-foot
#2
Teodoro Martín Noguerol, Antonio Luna Alcalá, Luis S Beltrán, Marta Gómez Cabrera, Jordi Broncano Cabrero, Joan C Vilanova
Diagnosis and treatment of foot disease in patients with diabetes is a common clinical-radiologic challenge, particularly the differentiation of neuropathic arthropathy from osteomyelitis. Conventional clinical tests and imaging techniques have limited accuracy for evaluation of the diabetic foot. The introduction of morphologic magnetic resonance (MR) imaging in these patients has provided a qualitative leap in diagnosis. The characteristics of soft-tissue and bone marrow edema and their patterns of distribution throughout the foot allow discrimination between both entities...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28679600/sural-nerve-injury-in-familial-amyloid-polyneuropathy-mr-neurography-vs-clinicopathologic-tools
#3
Jennifer Kollmer, Felix Sahm, Ute Hegenbart, Jan C Purrucker, Christoph Kimmich, Stefan O Schönland, Ernst Hund, Sabine Heiland, John M Hayes, Arnt V Kristen, Christoph Röcken, Mirko Pham, Martin Bendszus, Markus Weiler
OBJECTIVE: To detect and quantify lesions of the small-caliber sural nerve (SN) in symptomatic and asymptomatic transthyretin familial amyloid polyneuropathy (TTR-FAP) by high-resolution magnetic resonance neurography (MRN) in correlation with electrophysiologic and histopathologic findings. METHODS: Twenty-five patients with TTR-FAP, 10 asymptomatic carriers of the mutated transthyretin gene (mutTTR), and 35 age- and sex-matched healthy controls were prospectively included in this cross-sectional case-control study...
July 5, 2017: Neurology
https://www.readbyqxmd.com/read/28620719/large-coverage-mr-neurography-in-cidp-diagnostic-accuracy-and-electrophysiological-correlation
#4
Moritz Kronlage, Philipp Bäumer, Kalliopi Pitarokoili, Daniel Schwarz, Véronique Schwehr, Tim Godel, Sabine Heiland, Ralf Gold, Martin Bendszus, Min-Suk Yoon
The objective of this study was to evaluate large coverage magnetic resonance neurography (MRN) in chronic inflammatory demyelinating polyneuropathy (CIDP). In this prospective study, 18 patients with CIDP and 18 healthy controls were examined by a standardized MRN protocol at 3 T. Lumbosacral plexus was imaged by a T2-weighted 3D sequence and peripheral nerves of the upper and lower extremity by axial T2-weighted turbo spin-echo sequences. Lesions were characterized by nerve cross-sectional area (CSA) and T2-weighted signal (nT2)...
July 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28570096/advanced-mri-techniques-for-the-ankle
#5
Palanan Siriwanarangsun, Won C Bae, Sheronda Statum, Christine B Chung
OBJECTIVE: The purposes of this article are to present a state-of-the-art routine protocol for MRI of the ankle, to provide problem-solving tools based on specific clinical indications, and to introduce principles for the implementation of ultrashort echo time MRI of the ankle, including morphologic and quantitative assessment. CONCLUSION: Ankle injury is common among both athletes and the general population, and MRI is the established noninvasive means of evaluation...
June 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28567306/mr-micro-neurography-and-a-segmentation-protocol-applied-to-diabetic-neuropathy
#6
P F Felisaz, G Maugeri, V Busi, R Vitale, F Balducci, S Gitto, P Leporati, A Pichiecchio, M Baldi, F Calliada, L Chiovato, S Bastianello
The aim of this study was to assess with MRI morphometric ultrastructural changes in nerves affected by diabetic peripheral neuropathy (DPN). We used an MR micro-neurography imaging protocol and a semiautomated technique of tissue segmentation to visualize and measure the volume of internal nerve components, such as the epineurium and nerve fascicles. The tibial nerves of 16 patients affected by DPN and of 15 healthy volunteers were imaged. Nerves volume (NV), fascicles volume (FV), fascicles to nerve ratio (FNR), and nerves cross-sectional areas (CSA) were obtained...
2017: Radiology Research and Practice
https://www.readbyqxmd.com/read/28500667/magnetic-resonance-neurography-and-diffusion-tensor-imaging-of-the-peripheral-nerves-in-patients-with-cmt-type-1a
#7
Michael Vaeggemose, Signe Vaeth, Mirko Pham, Steffen Ringgaard, Uffe B Jensen, Hatice Tankisi, Niels Ejskjaer, Sabine Heiland, Henning Andersen
INTRODUCTION: Investigation of peripheral neuropathies by magnetic resonance neurography (MRN) may provide increased diagnostic accuracy when performed in combination with diffusion tensor imaging (DTI). The aim of this study was to evaluate DTI in the detection of neuropathic abnormalities in Charcot-Marie-Tooth-type-1A (CMT1A). METHODS: MR imaging of the sciatic and tibial nerves, including MRN and DTI, was prospectively performed in 15 CMT1A patients and 30 healthy-controls (HC)...
May 13, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28453433/diagnostic-accuracy-of-selective-3-t-mr-neurography-guided-retroperitoneal-genitofemoral-nerve-blocks-for-the-diagnosis-of-genitofemoral-neuralgia
#8
Jan Fritz, A Lee Dellon, Eric H Williams, Gedge D Rosson, Allan J Belzberg, Frederick E Eckhauser
Purpose To determine if 3-T magnetic resonance (MR) neurography-guided retroperitoneal genitofemoral nerve (GFN) blocks are safe and effective for the diagnosis of genitofemoral neuralgia. Materials and Methods Following institutional review board approval and informed consent, 26 subjects (16 men, 10 women; mean age, 42 years [range, 24-78 years]; mean body mass index, 28 kg/m(2) [range, 20-35 kg/m(2)]) with intractable groin pain were included. By using a 3-T MR imaging system, intermediate-weighted turbo spin-echo pulse sequences, and MR-conditional needles, diagnostic MR neurography-guided GFN blocks were performed in the retroperitoneum...
April 28, 2017: Radiology
https://www.readbyqxmd.com/read/28432188/magnetic-resonance-neurography-visualizes-abnormalities-in-sciatic-and-tibial-nerves-in-patients-with-type-1-diabetes-and-neuropathy
#9
Michael Vaeggemose, Mirko Pham, Steffen Ringgaard, Hatice Tankisi, Niels Ejskjaer, Sabine Heiland, Per L Poulsen, Henning Andersen
This study evaluates whether diffusion-tensor-imaging MR-Neurography (DTI-MRN), T2-relaxation-time and proton-spin-density can detect and grade neuropathic abnormalities in patients with type 1 diabetes.Forty-nine patients with type 1 diabetes (11 with severe polyneuropathy (sDPN), 13 with mild polyneuropathy (mDPN) and 25 without polyneuropathy (nDPN)) and 30 healthy controls (HC) were included. Clinical examinations, nerve-conduction-studies and vibratory-perception-thresholds determined the presence and severity of DPN...
April 21, 2017: Diabetes
https://www.readbyqxmd.com/read/28339446/pulsed-radiofrequency-ablation-of-pudendal-nerve-for-treatment-of-a-case-of-refractory-pelvic-pain
#10
Vadim Petrov-Kondratov, Avneesh Chhabra, Stephanie Jones
Pudendal neuralgia (PN) is a result of pudendal nerve entrapment or injury, also called "Alcock syndrome." Pain that develops is often chronic, and at times debilitating. If conservative measures fail, invasive treatment modalities can be considered. The goal of this case report is to add to a small body of literature that a pulsed radiofrequency (PRF) ablation can be effectively used to treat PN and to show that high resolution MR neurography imaging can be used to detect pudendal neuropathy. CASE PRESENTATION: We present a case of a 51-year-old woman with 5 years of worsening right groin and vulva pain...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28261861/orthogonally-combined-motion-and-diffusion-sensitized-driven-equilibrium-oc-mdsde-preparation-for-vessel-signal-suppression-in-3d-turbo-spin-echo-imaging-of-peripheral-nerves-in-the-extremities
#11
Barbara Cervantes, Jan S Kirschke, Elizabeth Klupp, Hendrik Kooijman, Peter Börnert, Axel Haase, Ernst J Rummeny, Dimitrios C Karampinos
PURPOSE: To design a preparation module for vessel signal suppression in MR neurography of the extremities, which causes minimal attenuation of nerve signal and is highly insensitive to eddy currents and motion. METHODS: The orthogonally combined motion- and diffusion-sensitized driven equilibrium (OC-MDSDE) preparation was proposed, based on the improved motion- and diffusion-sensitized driven equilibrium methods (iMSDE and FC-DSDE, respectively), with specific gradient design and orientation...
March 5, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28213852/-imaging-of-the-lumbosacral-plexus-diagnostics-and-treatment-planning-with-high-resolution-procedures
#12
S Jengojan, C Schellen, G Bodner, G Kasprian
BACKGROUND: Technical advances in magnetic resonance (MR) and ultrasound-based neurography nowadays facilitate the radiological assessment of the lumbosacral plexus. OBJECTIVE: Anatomy and imaging of the lumbosacral plexus and diagnostics of the most common pathologies. MATERIAL AND METHODS: Description of the clinically feasible combination of magnetic resonance imaging (MRI) and ultrasound diagnostics, case-based illustration of imaging techniques and individual advantages of MRI and ultrasound-based diagnostics for various pathologies of the lumbosacral plexus and its peripheral nerves...
February 17, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28188347/-tumors-of-peripheral-nerves
#13
Michael Ho, Amelie M Lutz
BACKGROUND: Differentiation between malignant and benign tumors of peripheral nerves in the early stages is challenging; however, due to the unfavorable prognosis of malignant tumors early identification is required. OBJECTIVES: To show the possibilities for detection, differential diagnosis and clinical management of peripheral nerve tumors by imaging appearance in magnetic resonance (MR) neurography. MATERIAL AND METHODS: Review of current literature available in PubMed and MEDLINE, supplemented by the authors' own observations in clinical practice...
February 10, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28168620/-diagnostic-criteria-in-mr-neurography
#14
P Bäumer
Peripheral neuropathies are frequent and can mostly be correctly diagnosed by clinical examination and electrophysiology; however, diagnostically difficult cases are sometimes encountered especially with respect to precise localization of nerve lesions. Imaging of the peripheral nervous system has been shown to provide additional useful diagnostic information. In addition to the more widely available nerve sonography, magnetic resonance neurography (MRN) is the method of choice in diagnostically complex cases...
February 6, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28059708/impact-of-mr-neurography-in-patients-with-chronic-cauda-equina-syndrome-presenting-as-chronic-pelvic-pain-and-dysfunction
#15
J R Petrasic, A Chhabra, K M Scott
BACKGROUND AND PURPOSE: Chronic cauda equina syndrome, defined as persistent damage of the cauda equina nerve roots within the spinal canal can be a challenging diagnosis with varied presentations. MR neurography imaging is more commonly being used to evaluate the lumbosacral spine of patients suspected of having subacute or chronic cauda equina syndrome. Our aim was to evaluate the impact of lumbosacral plexus MR neurography in the diagnostic thinking and therapeutic management of patients presenting with chronic pelvic pain and dysfunction and suspected chronic cauda equina syndrome...
February 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28005489/mr-neurography-of-brachial-plexus-at-3-0-t-with-robust-fat-and-blood-suppression
#16
Xinzeng Wang, Crystal Harrison, Yogesh K Mariappan, Karthik Gopalakrishnan, Avneesh Chhabra, Robert E Lenkinski, Ananth J Madhuranthakam
Purpose To develop and evaluate magnetic resonance (MR) neurography of the brachial plexus with robust fat and blood suppression for increased conspicuity of nerves at 3.0 T in clinically feasible acquisition times. Materials and Methods This prospective study was HIPAA compliant, with institutional review board approval and written informed consent. A low-refocusing-flip-angle three-dimensional (3D) turbo spin-echo (TSE) sequence was modified to acquire both in-phase and out-of-phase echoes, required for chemical shift (Dixon) reconstruction, in the same repetition by using partial echoes combined with modified homodyne reconstruction with phase preservation...
May 2017: Radiology
https://www.readbyqxmd.com/read/27906945/ganglion-cyst-at-the-proximal-tibiofibular-joint-in-a-patient-with-painless-foot-drop
#17
Abdulmuhsen Alsahhaf, Waleed Renno
Entrapment neuropathies of the fibular nerve and its branches are often underdiagnosed due to the lack of reliable diagnosis using clinical examination and electrophysiologic evaluation. Most fibular nerve compressions may be classified into 2 broad categories: (a) mechanical causes, which occur at fibrous or fibro-osseous tunnels, and (b) dynamic causes related to nerve injury during specific limb positioning. Foot drop resulting from weakness of the dorsiflexor muscles of the foot is a relatively uncommon presentation and closely related to L5 neuropathy caused by a disc herniation...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27862251/anatomic-variability-of-the-lateral-femoral-cutaneous-nerve-value-of-3t-mri-in-identifying-anomaly-for-surgical-intervention
#18
Jan Fritz, Denniz Zolnoun, A Lee Dellon
The anatomic variability of the lateral femoral cutaneous nerve (LFC) creates diagnostic as well as therapeutic problems. A case is reported in which a woman with complaints of pain in the anterior and lateral thigh was referred for evaluation. Symptoms arose after an abdominal hysterectomy. Her symptoms were the territory of the LFC and not of the L2/L3 dermatome. She had a Tinel sign that was positive for the LFC skin territory, but this was located over the anterior superior iliac spine (ASIS), instead of medial to it...
February 2017: Microsurgery
https://www.readbyqxmd.com/read/27857458/magnetic-resonance-neurographic-confirmation-of-extensive-plexiform-neurofibroma-in-neurofibromatosis-1-presenting-as-ambiguous-genitalia
#19
Ishan Kumar, Ashish Verma, Ritu Ojha, Priyanka Aggarwal, Ram C Shukla, Arvind Srivastava
Genitourinary involvement of neurofibromatosis is uncommon and genital neurofibromatosis is even rarer. Involvement of clitoris by neurofibroma can lead to clitoromegaly masquerading as a male penis. We report such a case of ambiguous genitalia in a 7-year-old female child presenting with clitoromegaly since birth, in which magnetic resonance imaging (MRI) revealed the presence of extensive neurofibromatosis in the clitoris and lumbosacral regions. We emphasize the central role of MRI in evaluation of hormonal and non-hormonal causes of ambiguous genitalia...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27828983/sacrotuberous-ligament-healing-following-surgical-division-during-transgluteal-pudendal-nerve-decompression-a-3-tesla-mr-neurography-study
#20
Jan Fritz, Benjamin Fritz, A Lee Dellon
Pelvic pain due to chronic pudendal nerve (PN) compression, when treated surgically, is approached with a transgluteal division of the sacrotuberous ligament (STL). Controversy exists as to whether the STL heals spontaneously or requires grafting. Therefore, the aim of this study was to determine how surgically divided and unrepaired STL heal. A retrospective evaluation of 10 patients who had high spatial resolution 3-Tesla magnetic resonance imaging (3T MRI) exams of the pelvis was done using an IRB-approved protocol...
2016: PloS One
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