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Fluids reposition

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https://www.readbyqxmd.com/read/29234230/traumatic-eye-ball-luxation-a-stepwise-approach-to-globe-salvage
#1
Himika Gupta, Srivalli Natarajan, Sushrut Vaidya, Shipra Gupta, Dinesh Shah, Raj Merchant, Shrikant Deshpande
Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF) leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG) biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28662635/an-alternative-technique-for-descemet-s-membrane-detachment-following-phacoemulsification-case-report-and-review-of-literature
#2
REVIEW
Yan Weng, Yu-Ping Ren, Li Zhang, Xiao-Dan Huang, Xing-Chao Shen-Tu
BACKGROUND: Descemet's membrane detachment (DMD) is one of the most serious complications of modern cataract surgery. We present an alternative technique for management of DMD with a review of the literature on current strategies for the treatment of DMD. CASE PRESENTATION: A 74-year-old woman developed DMD after phacoemulsification and failed the first descemetopexy with air tamponade. An alternative method was used to drain the pre-descematic fluid and reposition the detached Descemet's membrane in this rare case...
June 29, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28566576/from-the-viewpoint-of-drug-metabolism-research
#3
REVIEW
Miki Nakajima
Since more than 70% of clinically used drugs are excreted from the body through metabolic processes, drug metabolism is a key determinant of pharmacokinetics, drug response and drug toxicity. Much progress has been made in understanding drug-drug interactions via the inhibition or induction of cytochrome P450s (P450, CYP), as well as the effects of genetic polymorphisms of P450s on pharmacokinetics, and this has facilitated the progress of optimized pharmacotherapy in the clinic. Now, similar information is needed for non-CYP enzymes, especially concerning Phase I enzymes, based on advanced basic and clinical studies...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28473116/elevated-mitral-valve-pressure-gradient-after-mitraclip-implantation-deteriorates-long-term-outcome-in-patients-with-severe-mitral-regurgitation-and-severe%C3%A2-heart-failure
#4
Michael Neuss, Thomas Schau, Akihiro Isotani, Markus Pilz, Maren Schöpp, Christian Butter
OBJECTIVES: This single-center study was performed to analyze the effect of an increased transvalvular gradient after the MitraClip (MC) (Abbott Laboratories, Abbott Park, Illinois) procedure on patient outcome during follow-up. BACKGROUND: Percutaneous transcatheter repair of the mitral valve with the MC device has been established as a novel technique for patients with severe mitral regurgitation and high surgical risk. This study investigated the influence of an increased pressure gradient after MC implantation on the long-term outcome of patients...
May 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28413525/post-ventriculoperitoneal-shunt-abdominal-pseudocyst-challenges-posed-in-management
#5
Raashid Hamid, Aejaz A Baba, Nisar A Bhat, Gowhar Mufti, Younis A Mir, Wani Sajad
BACKGROUND: In patients with hydrocephalus, the abdominal cavity has been used for absorption of cerebrospinal fluid (CSF) since 1905. Ventriculoperitoneal (VP) shunt operation is followed by abdominal complications in about 5-47% cases. Abdominal CSF pseudo cyst is an uncommon, but well described complication. AIM: This survey was conducted to study the clinical profile and management of this entity. We present our experience with cases of CSF pseudo cyst in children...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28250638/odontoidectomy-through-posterior-midline-approach-followed-by-same-sitting-occipitocervical-fixation-a-cadaveric-study
#6
Ehab Mohamed Eissa, Mohamed Mohi Eldin
OBJECT: Atlantoaxial instability with irreducible odontoid process is one of the challenges in spine surgery. These lesions are commonly treated through anterior transoral approach which is followed by posterior atlantoaxial fusion. However, there are still many limitations, especially cerebrospinal fluid fistula with subsequent life-threatening infection, difficulty in cases with limited opening of mouth due to temporomandibular arthritis or anomalies of naso-oropharynx. Türe et al...
January 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28208688/the-impact-of-heat-exposure-and-sleep-restriction-on-firefighters-work-performance-and-physiology-during-simulated-wildfire-suppression
#7
RANDOMIZED CONTROLLED TRIAL
Grace E Vincent, Brad Aisbett, Brianna Larsen, Nicola D Ridgers, Rod Snow, Sally A Ferguson
This study was designed to examine the effects of ambient heat on firefighters' physical task performance, and physiological and perceptual responses when sleep restricted during simulated wildfire conditions. Thirty firefighters were randomly allocated to the sleep restricted (n = 17, SR; 19 °C, 4-h sleep opportunity) or hot and sleep restricted (n = 13, HOT + SR; 33 °C, 4-h sleep opportunity) condition. Firefighters performed two days of simulated, intermittent, self-paced work circuits comprising six firefighting tasks...
February 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28202890/a-case-of-upside-down-stomach-that-was-effectively-treated-by-postprandial-repositioning
#8
Kazumasa Ono, Hiroshi Hasegawa, Toshimasa Obara, Kei Miyagishima, Shinichiro Inoue, Koichi Kozaki
An 88-year-old woman with a history of stomach perforation and lumbar compression fracture was admitted to our hospital with a chief complaint of continuous vomiting, which she had experienced since the previous day. She showed vomiting, spontaneous pain and tenderness from the epigastric fossa through the left flank. In addition, she had marked kyphosis. On a CT scan, although the fornix was located in the abdominal cavity, the antrum and body had escaped into the thoracic cavity. A large volume of gastric content was observed...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/28042062/end-of-life-care-and-quality-of-dying-in-23-acute-geriatric-hospital-wards-in-flanders-belgium
#9
Rebecca Verhofstede, Tinne Smets, Joachim Cohen, Kim Eecloo, Massimo Costantini, Nele Van Den Noortgate, Luc Deliens
OBJECTIVES: To describe the nursing and medical interventions performed in the last 48 hours of life and the quality of dying of patients dying in acute geriatric hospital wards. METHODS: Cross-sectional descriptive study between October 1, 2012 and September 30, 2013. Twenty-three acute geriatric wards in 13 hospitals in Flanders, Belgium. Patients hospitalized for more than 48 hours before dying in the participating wards. Structured after-death questionnaires, filled out by the nurse, the physician, and the family carer most involved in end-of-life care...
December 29, 2016: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28040257/the-2016-update-of-the-international-study-group-isgps-definition-and-grading-of-postoperative-pancreatic-fistula-11-years-after
#10
REVIEW
Claudio Bassi, Giovanni Marchegiani, Christos Dervenis, Micheal Sarr, Mohammad Abu Hilal, Mustapha Adham, Peter Allen, Roland Andersson, Horacio J Asbun, Marc G Besselink, Kevin Conlon, Marco Del Chiaro, Massimo Falconi, Laureano Fernandez-Cruz, Carlos Fernandez-Del Castillo, Abe Fingerhut, Helmut Friess, Dirk J Gouma, Thilo Hackert, Jakob Izbicki, Keith D Lillemoe, John P Neoptolemos, Attila Olah, Richard Schulick, Shailesh V Shrikhande, Tadahiro Takada, Kyoichi Takaori, William Traverso, Charles R Vollmer, Christopher L Wolfgang, Charles J Yeo, Roberto Salvia, Marcus Buchler
BACKGROUND: In 2005, the International Study Group of Pancreatic Fistula developed a definition and grading of postoperative pancreatic fistula that has been accepted universally. Eleven years later, because postoperative pancreatic fistula remains one of the most relevant and harmful complications of pancreatic operation, the International Study Group of Pancreatic Fistula classification has become the gold standard in defining postoperative pancreatic fistula in clinical practice. The aim of the present report is to verify the value of the International Study Group of Pancreatic Fistula definition and grading of postoperative pancreatic fistula and to update the International Study Group of Pancreatic Fistula classification in light of recent evidence that has emerged, as well as to address the lingering controversies about the original definition and grading of postoperative pancreatic fistula...
March 2017: Surgery
https://www.readbyqxmd.com/read/27993737/bolstering-the-nasoseptal-flap-using-sphenoid-sinus-fat-packing-a-technical-case-report
#11
Hussam Abou-Al-Shaar, Hasan A Zaidi, David J Cote, Edward R Laws
BACKGROUND: Resection of extensive skull base lesions often necessitates relatively large dural openings and arachnoid, resulting in skull base defects with the potential for a postoperative cerebrospinal fluid leak. A nasoseptal flap (NSF) is a vascularized graft that has greatly diminished the incidence of cerebrospinal fluid leak. Annealing of flaps against the ventral skull base can be tenuous within the first few days after surgery. We report the use of sphenoid sinus fat packing as a buttress to support the nasoseptal flap during skull base reconstruction...
March 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27914839/late-in-the-bag-intraocular-lens-dislocation-a-randomized-clinical-trial-comparing-lens-repositioning-and-lens-exchange
#12
RANDOMIZED CONTROLLED TRIAL
Olav Kristianslund, Marianne Råen, Atle E Østern, Liv Drolsum
PURPOSE: To compare the efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN: Prospective, randomized, parallel-group surgical trial. PARTICIPANTS: Patients referred to Oslo University Hospital (tertiary referral center). METHODS: We randomly assigned 104 patients (104 eyes) either to IOL repositioning by scleral suturing (n = 54) or to IOL exchange with retropupillary fixation of an iris-claw IOL (n = 50)...
February 2017: Ophthalmology
https://www.readbyqxmd.com/read/27779564/x-linked-malformation-and-cochlear-implantation
#13
Henrik Smeds, Jeremy Wales, Filip Asp, Ulrika Löfkvist, Babak Falahat, Britt-Marie Anderlid, Lena Anmyr, Eva Karltorp
OBJECTIVE: To evaluate if cochlear implantation is safe and constitutes an option for hearing rehabilitation of children with x-linked inner ear malformation. STUDY DESIGN: Retrospective patient review in combination with a multidisciplinary follow-up. SETTING: Tertiary referral hospital and cochlear implant program. PATIENTS: Ten children with severe-profound mixed hearing loss and radiological findings consistent with Incomplete Partition type 3 cochlear malformation received cochlear implants during the years 2007 to 2015...
January 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/27729765/single-suture-customized-loop-for-large-iridodialysis-repair
#14
Mohamed Omar Yousif
Managing large iridodialysis that may occur during phacoemulsification is challenging. I describe how a procedure to reposit a prolapsed iris while the anterior chamber is markedly inflated by a current of infusion fluid may inadvertently lead to large iridodialysis, and discuss how to avoid such a complication. I describe a fast and efficient technique for managing large iridodialysis both immediately, once it occurs, or as a secondary maneuver. My technique involved fixing the iris periphery back to its root at the anterior chamber angle using 10-0 polypropylene suture with two straight needles introduced directly through the cornea at distant points, and an insulin syringe as a guide track to a point 1...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27649104/intraparenchymal-hematoma-as-a-late-complication-of-retrograde-intrarenal-surgery
#15
Sedat Yahsi, Senol Tonyali, Cavit Ceylan, Kenan Y Yildiz, Levent Ozdal
A 34 year-old woman was admitted to our hospital with left flank pain. A non-contrast enhanced computerized tomography (NCCT) revealed a 1.5x2cm left proximal ureter stone. Patient was scheduled for ureterorenoscopy (URS) and stone removal. She was submitted to retrograde intrarenal surgery (RIRS). At the postoperative 1st day, the patient began to suffer from left flank pain. A NCCT was taken, which revealed a subcapsular hematoma and perirenal fluid. The patient was managed conservatively with intravenous fluid, antibiotic and non-steroidal anti-inflammatory drug therapy and was discharged at the postoperative 6th day...
March 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27627386/microscopic-modeling-of-confined-crystal-growth-and-dissolution
#16
Jørgen Høgberget, Anja Røyne, Dag K Dysthe, Espen Jettestuen
We extend the (1+1)-dimensional fluid solid-on-solid (SOS) model to include a confining flat surface opposite to the SOS surface subject to a constant load. This load is balanced by a repulsive surface-surface interaction given by an ansatz which agrees with known analytical solutions in the limit of two separated flat surfaces. Mechanical equilibrium is imposed at all times by repositioning the confining surface. By the use of kinetic Monte Carlo (KMC) we calculate how the equilibrium concentration (deposition rate) depends on the applied load, and find it to reproduce analytical thermodynamics independent of the parameters of the interaction ansatz...
August 2016: Physical Review. E
https://www.readbyqxmd.com/read/27538866/minimally-invasive-lumbar-port-system-for-the-collection-of-cerebrospinal-fluid-from-rhesus-macaques-macaca-mulatta
#17
Rhonda Pung MacAllister, Cynthia M Lester McCully, John Bacher, Marvin L Thomas, Rafael Cruz, Solomon Wangari, Katherine E Warren
Biomedical translational research frequently incorporates collection of CSF from NHP, because CSF drug levels are used as a surrogate for CNS tissue penetration in pharmacokinetic and dynamic studies. Surgical placement of a CNS ventricular catheter reservoir for CSF collection is an intensive model to create and maintain and thus may not be feasible or practical for short-term studies. Furthermore, previous NHP lumbar port models require laminectomy for catheter placement. The new model uses a minimally invasive technique for percutaneous placement of a lumbar catheter to create a closed, subcutaneous system for effective, repeated CSF sample collection...
2016: Comparative Medicine
https://www.readbyqxmd.com/read/27525707/auditory-brainstem-implantation-in-neurofibromatosis-type-2-experience-from-the-manchester-programme
#18
Richard Thomas Ramsden, Simon Richard Mackenzie Freeman, Simon Kingsley Wickham Lloyd, Andrew Thomas King, Xin Shi, Charlotte Lucy Ward, Susan Mary Huson, Deborah Jane Mawman, Martin Paul O'Driscoll, Dafydd Gareth Evans, Scott Alexander Rutherford
OBJECTIVE: To describe the experience of auditory brainstem implantation (ABI) in patients with Neurofibromatosis type 2 (NF2). STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral centre. PATIENTS: Implanted with a Cochlear ABI22 or ABI24M between 1994 and 2009 because of NF2 disease. INTERVENTION(S): Rehabilitative. MAIN OUTCOME MEASURE(S): Surgical complication rate; audiological outcomes...
October 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27491044/closing-macular-holes-with-macular-plug-without-gas-tamponade-and-postoperative-posturing
#19
Meena Chakrabarti, Preethi Benjamin, Keya Chakrabarti, Arup Chakrabarti
PURPOSE: To investigate the surgical results of macular hole surgery without gas tamponade or postoperative posturing in patients with Stage 3 and Stage 4 macular holes with ≥500 μm mean base diameter. DESIGN: Retrospective interventional case series. PARTICIPANTS: Twenty-six patients with Stage 3 and Stage 4 macular holes. METHODS: Twenty-six eyes of 26 patients with Stage 3 and Stage 4 macular holes and a mean base diameter of 892...
March 2017: Retina
https://www.readbyqxmd.com/read/27449745/development-of-inhalable-hyaluronan-mannitol-composite-dry-powders-for-flucytosine-repositioning-in-local-therapy-of-lung-infections
#20
G Costabile, I d'Angelo, R d'Emmanuele di Villa Bianca, E Mitidieri, B Pompili, P Del Porto, L Leoni, P Visca, A Miro, F Quaglia, F Imperi, R Sorrentino, F Ungaro
Flucytosine (5-fluorocytosine, 5-FC) is a fluorinated analogue of cytosine currently approved for the systemic treatment of fungal infections, which has recently demonstrated a very promising antivirulence activity against the bacterial pathogen Pseudomonas aeruginosa. In this work, we propose novel inhalable hyaluronic acid (HA)/mannitol composite dry powders for repositioning 5-FC in the local treatment of lung infections, including those affecting cystic fibrosis (CF) patients. Different dry powders were produced in one-step by spray-drying...
September 28, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
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