Gisela Lilja, Susann Ullén, Josef Dankiewicz, Hans Friberg, Helena Levin, Erik Blennow Nordström, Katarina Heimburg, Janus Christian Jakobsen, Marita Ahlqvist, Frances Bass, Jan Belohlavek, Roy Bjørkholt Olsen, Alain Cariou, Glenn Eastwood, Hans Rune Fanebust, Anders M Grejs, Lisa Grimmer, Naomi E Hammond, Jan Hovdenes, Juraj Hrecko, Manuela Iten, Henriette Johansen, Thomas R Keeble, Hans Kirkegaard, Jean-Baptiste Lascarrou, Christoph Leithner, Mildred Eden Lesona, Anja Levis, Marco Mion, Marion Moseby-Knappe, Leanlove Navarra, Per Nordberg, Paolo Pelosi, Rachael Quayle, Christian Rylander, Helena Sandberg, Manoj Saxena, Claudia Schrag, Michal Siranec, Cassina Tiziano, Philippe Vignon, Pedro David Wendel-Garcia, Matt P Wise, Kim Wright, Niklas Nielsen, Tobias Cronberg
IMPORTANCE: The Targeted Hypothermia vs Targeted Normothermia After Out-of-Hospital Cardiac Arrest (TTM2) trial reported no difference in mortality or poor functional outcome at 6 months after out-of-hospital cardiac arrest (OHCA). This predefined exploratory analysis provides more detailed estimation of brain dysfunction for the comparison of the 2 intervention regimens. OBJECTIVES: To investigate the effects of targeted hypothermia vs targeted normothermia on functional outcome with focus on societal participation and cognitive function in survivors 6 months after OHCA...
October 1, 2023: JAMA Neurology