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https://www.readbyqxmd.com/read/29223615/differences-in-drug-susceptibility-pattern-between-mycobacterium-avium-and-mycobacterium-intracellulare-isolated-in-respiratory-specimens
#1
Eun Hye Cho, Hee Jae Huh, Dong Joon Song, Seong Mi Moon, Seung-Heon Lee, So Youn Shin, Chang Ki Kim, Chang-Seok Ki, Won-Jung Koh, Nam Yong Lee
Mycobacterium avium complex (MAC) is the most common etiologic organisms of nontuberculous mycobacteria (NTM) lung disease. In this study, we aimed to retrospectively investigate the differences in drug susceptibility patterns of two major MAC species; Mycobacterium avium and Mycobacterium intracellulare. A total of 1883 major two MAC isolates (1060 M. avium and 823 M. intracellulare) from respiratory specimens were included in this study during the period 2011─2016. The minimum inhibitory concentrations (MICs) were determined by broth microdilution method and MIC50/MIC90 values were derived from MIC distribution...
December 6, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29223588/-9-o-%C3%AE-l-rhamnopyranosyl-lyoniresinol-from-lespedeza-cuneata-suppresses-ovarian-cancer-cell-proliferation-through-induction-of-apoptosis
#2
Jiwon Baek, Dahae Lee, Tae Kyoung Lee, Ji Hoon Song, Ju Sung Lee, Seong Lee, Sang-Woo Yoo, Ki Sung Kang, Eunjung Moon, Sanghyun Lee, Ki Hyun Kim
Lespedeza cuneata (Dum. Cours.) G. Don. (Fabaceae), known as Chinese bushclover or sericea lespedeza, has been used in traditional medicine to treat diabetes, hematuria, and insomnia, and it has been reported that bioactive compounds from L. cuneata possess various pharmacological properties. However, there has been no study to determine the active compounds from L. cuneata with potential activity against ovarian cancer. This study aimed to isolate cytotoxic compounds from L. cuneata and identify the molecular mechanisms underlying the apoptosis pathway in ovarian cancer cells...
November 28, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/29223138/plant-expressed-fc-fusion-protein-tetravalent-dengue-vaccine-with-inherent-adjuvant-properties
#3
Mi Young Kim, Alastair Copland, Kaustuv Nayak, Anmol Chandele, Muhammad Shamsher Ahmed, Qibo Zhang, Gil Reynolds Diogo, Matthew John Paul, Sven Hofmann, Moon-Sik Yang, Yong-Suk Jang, Julian K-C Ma, Rajko Reljic
Dengue is a major global disease requiring improved treatment and prevention strategies. The recently licensed Sanofi-Pasteur Denvaxia vaccine does not protect children under the age of nine and additional vaccine strategies are thus needed to halt this expanding global epidemic. Here, we employed a molecular engineering approach and plant-expression to produce a humanised and highly immunogenic Poly-Immunoglobulin G Scaffold (PIGS) fused to the consensus dengue envelope protein III domain (cEDIII). The immunogenicity of this IgG Fc receptor targeted vaccine candidate was demonstrated in transgenic mice expressing human FcγRI/CD64, by induction of neutralising antibodies and evidence of cell-mediated immunity...
December 9, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/29222812/spheroid-type-of-al-amyloid-deposition-associated-with-colonic-adenocarcinoma-a-case-report-with-literature-review
#4
Moon Joo Kim, Zulfia McCroskey, Yingchao Piao, Anna Belcheva, Luan Truong, Paul J Kurtin, Jae Y Ro
We report a colonic adenocarcinoma associated with diffuse submucosal deposition of a peculiar spheroid-type amyloid identified in the colon, terminal ileum, and appendix. A 65-year-old woman with past medical histories of hypertension, and chronic obstructive pulmonary disease, presented to the emergency room with cramping abdominal pain and nausea. A computed tomography (CT) scan of abdomen showed right colonic volvulus. Emergency right hemicolectomy was performed. The specimen showed colonic adenocarcinoma with focal submucosal invasion (pT1) arising from a villotubular adenoma...
December 8, 2017: Pathology International
https://www.readbyqxmd.com/read/29221273/clinical-outcomes-of-video-assisted-thoracoscopic-surgery-esophagectomy-for-esophageal-cancer-a-propensity-score-matched-analysis
#5
Duk Hwan Moon, Jong Mog Lee, Jae Hyun Jeon, Hee Chul Yang, Moon Soo Kim
Background: Minimally invasive esophagectomy theoretically offers advantages compared with open esophagectomy (OE). The aim of this study was to compare the early- and mid-term outcomes between video-assisted thoracoscopic surgery (VATS) esophagectomy (VE) and OE in patients with esophageal cancer. Methods: Between November 2011 and July 2015, a total of 172 patients were divided into two groups depending on the method of esophagectomy: the VE group (n=42) and the OE group (n=130)...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221146/swertiajaponin-inhibits-skin-pigmentation-by-dual-mechanisms-to-suppress-tyrosinase
#6
Bonggi Lee, Kyoung Mi Moon, Bong-Seon Lee, Ju-Hye Yang, Kwang Il Park, Won-Kyung Cho, Jin Yeul Ma
Many skin-whitening compounds target tyrosinase because it catalyzes two rate-limiting steps in melanin synthesis. Although many tyrosinase inhibitors are currently available for a skin-whitening purpose, undesirable adverse effects are also reported. Thus, numerous efforts have been made to develop safer tyrosinase inhibitors from natural products. In line with this, we tested fifty flavonoids, a group of naturally occurring antioxidants and metal chelators, and screened swertiajaponin as the strongest tyrosinase inhibitor in cell-free experiments...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29221064/nanoimprinted-perovskite-metasurface-for-enhanced-photoluminescence
#7
Honglei Wang, Shih-Chia Liu, Balasubramaniam Balachandran, Jiyoung Moon, Ross Haroldson, Zhitong Li, Artur Ishteev, Qing Gu, Weidong Zhou, Anvar Zakhidov, Walter Hu
Recently, solution-processed hybrid halide perovskite has emerged as promising materials for advanced optoelectronic devices such as photovoltaics, photodetectors, light emitting diodes and lasers. In the mean time, all-dielectric metasurfaces with high-index materials have attracted attention due to their low-loss and high-efficient optical resonances. Because of its tunable by composition band gap in the visible frequencies, organolead halide perovskite could serve as a powerful platform for realizing high-index, low-loss metasurfaces...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29220802/conducting-polymer-based-electrochemical-biosensors-for-neurotransmitters-a-review
#8
REVIEW
Jong-Min Moon, Neeta Thapliyal, Khalil Khadim Hussain, Rajendra N Goyal, Yoon-Bo Shim
Neurotransmitters are important biochemical molecules that control behavioral and physiological functions in central and peripheral nervous system. Therefore, the analysis of neurotransmitters in biological samples has a great clinical and pharmaceutical importance. To date, various methods have been developed for their assay. Of the various methods, the electrochemical sensors demonstrated the potential of being robust, selective, sensitive, and real time measurements. Recently, conducting polymers (CPs) and their composites have been widely employed in the fabrication of various electrochemical sensors for the determination of neurotransmitters...
December 5, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29219755/mitochondrial-abnormalities-related-to-the-dysfunction-of-circulating-endothelial-colony-forming-cells-in-moyamoya-disease
#9
Jung Won Choi, Sung Min Son, Inhee Mook-Jung, Youn Joo Moon, Ji Yeoun Lee, Kyu-Chang Wang, Hyun-Seung Kang, Ji Hoon Phi, Seung Ah Choi, Sangjoon Chong, Jayoung Byun, Seung-Ki Kim
OBJECTIVE Moyamoya disease (MMD) is a unique cerebrovascular disorder characterized by the progressive occlusion of the bilateral internal carotid arteries. Endothelial colony-forming cells (ECFCs), previously termed "endothelial progenitor cells," play an important role in the pathogenesis of MMD. In this study, the authors performed morphological and functional studies of the mitochondria of ECFCs from patients with MMD to present new insights into the pathogenesis of the disease. METHODS The morphology of ECFCs from 5 MMD patients and 5 healthy controls was examined under both a transmission electron microscope and a confocal laser scanning microscope...
December 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29219521/structural-%C3%AE-doping-to-control-local-magnetization-in-isovalent-oxide-heterostructures
#10
E J Moon, Q He, S Ghosh, B J Kirby, S T Pantelides, A Y Borisevich, S J May
Modulation and δ-doping strategies, in which atomically thin layers of charged dopants are precisely deposited within a heterostructure, have played enabling roles in the discovery of new physical behavior in electronic materials. Here, we demonstrate a purely structural "δ-doping" strategy in complex oxide heterostructures, in which atomically thin manganite layers are inserted into an isovalent manganite host, thereby modifying the local rotations of corner-connected MnO_{6} octahedra. Combining scanning transmission electron microscopy, polarized neutron reflectometry, and density functional theory, we reveal how local magnetic exchange interactions are enhanced within the spatially confined regions of suppressed octahedral rotations...
November 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29219495/evidence-for-isospin-violation-and-measurement-of-cp-asymmetries-in-b%C3%A2-k-892-%C3%AE
#11
T Horiguchi, A Ishikawa, H Yamamoto, I Adachi, H Aihara, S Al Said, D M Asner, V Aulchenko, T Aushev, R Ayad, V Babu, I Badhrees, A M Bakich, V Bansal, P Behera, V Bhardwaj, B Bhuyan, J Biswal, A Bobrov, G Bonvicini, A Bozek, M Bračko, T E Browder, D Červenkov, V Chekelian, A Chen, B G Cheon, K Chilikin, K Cho, Y Choi, D Cinabro, T Czank, N Dash, S Di Carlo, Z Doležal, Z Drásal, D Dutta, S Eidelman, D Epifanov, H Farhat, J E Fast, T Ferber, B G Fulsom, V Gaur, N Gabyshev, A Garmash, M Gelb, R Gillard, P Goldenzweig, B Golob, Y Guan, E Guido, J Haba, T Hara, K Hayasaka, H Hayashii, M T Hedges, T Higuchi, S Hirose, W-S Hou, T Iijima, K Inami, G Inguglia, R Itoh, Y Iwasaki, W W Jacobs, I Jaegle, H B Jeon, S Jia, Y Jin, D Joffe, K K Joo, T Julius, K H Kang, T Kawasaki, D Y Kim, J B Kim, K T Kim, M J Kim, S H Kim, Y J Kim, K Kinoshita, P Kodyš, S Korpar, D Kotchetkov, P Križan, P Krokovny, T Kuhr, R Kulasiri, R Kumar, T Kumita, A Kuzmin, Y-J Kwon, J S Lange, C H Li, L Li, L Li Gioi, J Libby, D Liventsev, M Lubej, T Luo, M Masuda, T Matsuda, D Matvienko, M Merola, K Miyabayashi, H Miyata, R Mizuk, G B Mohanty, S Mohanty, H K Moon, T Mori, R Mussa, E Nakano, M Nakao, T Nanut, K J Nath, Z Natkaniec, M Nayak, N K Nisar, S Nishida, S Ogawa, S Okuno, H Ono, P Pakhlov, G Pakhlova, B Pal, S Pardi, C-S Park, H Park, S Paul, T K Pedlar, R Pestotnik, L E Piilonen, K Prasanth, C Pulvermacher, J Rauch, A Rostomyan, Y Sakai, S Sandilya, L Santelj, V Savinov, O Schneider, G Schnell, C Schwanda, A J Schwartz, Y Seino, K Senyo, I S Seong, M E Sevior, V Shebalin, C P Shen, T-A Shibata, J-G Shiu, F Simon, A Sokolov, E Solovieva, M Starič, J F Strube, K Sumisawa, T Sumiyoshi, M Takizawa, U Tamponi, K Tanida, F Tenchini, K Trabelsi, M Uchida, T Uglov, Y Unno, S Uno, P Urquijo, Y Ushiroda, Y Usov, C Van Hulse, G Varner, A Vinokurova, V Vorobyev, A Vossen, C H Wang, M-Z Wang, P Wang, Y Watanabe, S Watanuki, T Weber, E Widmann, E Won, Y Yamashita, H Ye, Z P Zhang, V Zhilich, V Zhukova, V Zhulanov, A Zupanc
We report the first evidence for isospin violation in B→K^{*}γ and the first measurement of the difference of CP asymmetries between B^{+}→K^{*+}γ and B^{0}→K^{*0}γ. This analysis is based on the data sample containing 772×10^{6}BB[over ¯] pairs that was collected with the Belle detector at the KEKB energy-asymmetric e^{+}e^{-} collider. We find evidence for the isospin violation with a significance of 3.1σ, Δ_{0+}=[+6.2±1.5(stat)±0.6(syst)±1.2(f_{+-}/f_{00})]%, where the third uncertainty is due to the uncertainty on the fraction of B^{+}B^{-} to B^{0}B[over ¯]^{0} production in ϒ(4S) decays...
November 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29219447/search-for-cp-violation-and-measurement-of-the-branching-fraction-in-the-decay-d-0-%C3%A2-k_-s-0-k_-s-0
#12
N Dash, S Bahinipati, V Bhardwaj, K Trabelsi, I Adachi, H Aihara, S Al Said, D M Asner, V Aulchenko, T Aushev, R Ayad, V Babu, I Badhrees, A M Bakich, V Bansal, E Barberio, B Bhuyan, J Biswal, A Bobrov, A Bondar, G Bonvicini, A Bozek, M Bračko, F Breibeck, T E Browder, D Červenkov, M-C Chang, V Chekelian, A Chen, B G Cheon, K Chilikin, K Cho, Y Choi, D Cinabro, S Di Carlo, Z Doležal, Z Drásal, D Dutta, S Eidelman, D Epifanov, H Farhat, J E Fast, T Ferber, B G Fulsom, V Gaur, N Gabyshev, A Garmash, R Gillard, P Goldenzweig, J Haba, T Hara, K Hayasaka, H Hayashii, M T Hedges, W-S Hou, T Iijima, K Inami, A Ishikawa, R Itoh, Y Iwasaki, W W Jacobs, I Jaegle, H B Jeon, Y Jin, D Joffe, K K Joo, T Julius, J Kahn, A B Kaliyar, G Karyan, P Katrenko, T Kawasaki, C Kiesling, D Y Kim, H J Kim, J B Kim, K T Kim, M J Kim, S H Kim, Y J Kim, K Kinoshita, P Kodyš, S Korpar, D Kotchetkov, P Križan, P Krokovny, T Kuhr, R Kulasiri, R Kumar, T Kumita, A Kuzmin, Y-J Kwon, J S Lange, I S Lee, C H Li, L Li, Y Li, L Li Gioi, J Libby, D Liventsev, M Lubej, T Luo, M Masuda, D Matvienko, M Merola, K Miyabayashi, H Miyata, R Mizuk, G B Mohanty, S Mohanty, H K Moon, T Mori, R Mussa, E Nakano, M Nakao, T Nanut, K J Nath, Z Natkaniec, M Nayak, M Niiyama, N K Nisar, S Nishida, S Ogawa, S Okuno, H Ono, P Pakhlov, G Pakhlova, B Pal, S Pardi, C-S Park, H Park, S Paul, T K Pedlar, L Pesántez, R Pestotnik, L E Piilonen, K Prasanth, M Ritter, A Rostomyan, H Sahoo, Y Sakai, S Sandilya, L Santelj, T Sanuki, Y Sato, V Savinov, O Schneider, G Schnell, C Schwanda, A J Schwartz, Y Seino, K Senyo, M E Sevior, V Shebalin, C P Shen, T-A Shibata, J-G Shiu, B Shwartz, F Simon, A Sokolov, E Solovieva, M Starič, J F Strube, J Stypula, K Sumisawa, T Sumiyoshi, M Takizawa, U Tamponi, K Tanida, F Tenchini, M Uchida, T Uglov, Y Unno, S Uno, P Urquijo, Y Usov, C Van Hulse, G Varner, V Vorobyev, A Vossen, E Waheed, C H Wang, M-Z Wang, P Wang, M Watanabe, Y Watanabe, E Widmann, K M Williams, E Won, Y Yamashita, H Ye, J Yelton, Y Yook, C Z Yuan, Y Yusa, Z P Zhang, V Zhilich, V Zhukova, V Zhulanov, A Zupanc
We report a study of the decay D^{0}→K_{S}^{0}K_{S}^{0} using 921  fb^{-1} of data collected at or near the ϒ(4S) and ϒ(5S) resonances with the Belle detector at the KEKB asymmetric energy e^{+}e^{-} collider. The measured time-integrated CP asymmetry is A_{CP}(D^{0}→K_{S}^{0}K_{S}^{0})=(-0.02±1.53±0.02±0.17)%, and the branching fraction is B(D^{0}→K_{S}^{0}K_{S}^{0})=(1.321±0.023±0.036±0.044)×10^{-4}, where the first uncertainty is statistical, the second is systematic, and the third is due to the normalization mode (D^{0}→K_{S}^{0}π^{0})...
October 27, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29218569/toxin-positivity-and-tcdb-gene-load-in-broad-spectrum-clostridium-difficile-infection
#13
Hyeong Nyeon Kim, Hanah Kim, Hee-Won Moon, Mina Hur, Yeo-Min Yun
PURPOSE: This study aimed to evaluate the clinical significance of toxin positivity and toxin gene load, and the relation between them in the broad spectrum of Clostridium difficile infection (CDI) including colonization, significant diarrhea, and severe disease. METHODS: We included 2671 fecal samples submitted for CDI diagnosis and 180 samples from healthy individuals. The clinical spectrum was categorized as category I (toxigenic C. difficile positive without clinical CDI criteria), category II (mild CDI), and category III (severe CDI)...
December 7, 2017: Infection
https://www.readbyqxmd.com/read/29217266/auriculasin-induced-ros-causes-prostate-cancer-cell-death-via-induction-of-apoptosis
#14
Hyun-Dong Cho, Ju-Hye Lee, Kwang-Deog Moon, Ki-Hun Park, Mi-Kyung Lee, Kwon-Il Seo
Recent studies have demonstrated that natural agents targeting the accumulation of reactive oxygen species (ROS) that selectively kill, leaving normal cells undamaged, can suppress prostate cancer. Here, we show that auriculasin, derived from Flemingia philippinensis, induces significant cell death and apoptosis via ROS generation in prostate cancer cells. Auriculasin treatment resulted in selective apoptotic cell death in LNCaP prostate cancer cells, characterized by DNA fragmentation, accumulation of sub-G1 cell population, cleavage of poly (ADP-ribose) polymerase (PARP), regulation of Bax/Bcl-2 ratio, increase of cytosolic apoptosis-inducing factor (AIF) and endonuclease G (EndoG), in addition to inhibiting tumor growth in a xenograft mouse model...
December 4, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29216483/additional-prognostic-value-of-brachial-ankle-pulse-wave-velocity-to-coronary-computed-tomography-angiography-in-patients-with-suspected-coronary-artery-disease
#15
In-Chang Hwang, Kwang Nam Jin, Hack-Lyoung Kim, You-Nui Kim, Moon-Sun Im, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim
BACKGROUND AND AIMS: Increased arterial stiffness is associated with a higher risk of future cardiovascular events. We aimed to investigate whether information about arterial stiffness provides additional prognostic value to coronary computed tomography angiography (CCTA) findings. METHODS: A total of 523 consecutive patients (mean age, 58.0 ± 10.3 years; male, 60.6%) with suspected coronary artery disease (CAD), who underwent CCTA and brachial-ankle pulse wave velocity (baPWV) measurement within a month, were retrospectively analyzed...
December 1, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29215819/prevalence-of-malnutrition-in-hospitalized-patients-a-multicenter-cross-sectional-study
#16
Min Chang Kang, Ji Hoon Kim, Seung Wan Ryu, Jae Young Moon, Je Hoon Park, Jong Kyung Park, Jong Hoon Park, Hyun Wook Baik, Jeong Meen Seo, Myoung Won Son, Geun Am Song, Dong Woo Shin, Yeon Myung Shin, Hong Yup Ahn, Han Kwang Yang, Hee Chul Yu, Ik Jin Yun, Jae Gil Lee, Jae Myeong Lee, Jung Hwa Lee, Tae Hee Lee, Haejun Yim, Hyun Jeong Jeon, Kyuwhan Jung, Mi Ran Jung, Chi Young Jeong, Hee Sook Lim, Suk Kyung Hong
BACKGROUND: Malnutrition is associated with many adverse clinical outcomes. The present study aimed to identify the prevalence of malnutrition in hospitalized patients in Korea, evaluate the association between malnutrition and clinical outcomes, and ascertain the risk factors of malnutrition. METHODS: A multicenter cross-sectional study was performed with 300 patients recruited from among the patients admitted in 25 hospitals on January 6, 2014. Nutritional status was assessed by using the Subjective Global Assessment (SGA)...
January 8, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29215805/development-of-the-suicide-risk-scale-for-medical-inpatients
#17
Sang Won Park, Jong Ha Lee, Eun Kyoung Lee, Jae Jun Song, Hong Seok Park, Soon Young Hwang, Moon Soo Lee
BACKGROUND: Inpatient suicide is one of the major issues related with hospital patient safety. Although there are many studies addressing suicide in the psychiatric unit, little is known about suicide in a medical setting. This study included the development and validation of a screening tool for the assessment of suicide risk, specialized for medical inpatients. METHODS: The preliminary questionnaire was based on review of previous suicide ideation scales, mood scales, and clinical experiences of psychiatrists and clinical psychologists in Korea...
January 15, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29215592/natural-korean-medicine-dang-gui-biosynthesis-effective-extraction-and-formulations-of-major-active-pyranocoumarins-their-molecular-action-mechanism-in-cancer-and-other-biological-activities
#18
REVIEW
Chinreddy Subramanyam Reddy, Seong Cheol Kim, Mok Hur, Yeon Bok Kim, Chun Geon Park, Woo Moon Lee, Jae Ki Jang, Sung Cheol Koo
Angelica gigas Nakai (AGN) is a crucial oriental medicinal herb that grows especially in Korea and the Far-East countries. It contains chemically active compounds like pyranocoumarins, polyacetylenes and essential oils, which might be useful for treatment of several chronic diseases. It has been used for centuries as a traditional medicine in Southeast Asia, but in Western countries is used as a functional food and a major ingredient of several herbal products. The genus Angelica is also known as 'female ginseng' due to its critical therapeutic role in female afflictions, such as gynecological problems...
December 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29215259/novel-flexible-transparent-conductive-films-with-enhanced-chemical-and-electro-mechanical-sustainability-tio2-nanosheet-ag-nanowire-hybrid
#19
Hiesang Sohn, Se Yun Kim, Weon Ho Shin, Jong Min Lee, Hyangsook Lee, Dong-Jin Yun, Kyoung-Seok Moon, Intaek Han, Chan Kwak, Seong-Ju Hwang
Flexible transparent conductive films (TCFs) of TiO2 nanosheet (TiO2 NS) and silver nanowire (Ag NW) network hybrid were prepared through a simple and scalable solution-based process. As-formed TiO2 NS-Ag NW hybrid TCF shows a high optical transmittance (TT: 97% (90.2% including plastic substrate)) and low sheet resistance (Rs: 40 ohm/sq.). In addition, TiO2 NS-Ag NW hybrid TCF exhibits a long-time chemical/ageing and electro-mechanical stability. As for the chemical/ageing stability, the hybrid TCF of Ag NW and TiO2 NS reveals a retained initial conductivity (ΔRs/Rs <1%) under ambient oxidant gas over a month, superior to that of bare Ag NW (ΔRs/Rs >4000%) or RuO2 NS-Ag NW hybrid (ΔRs/Rs >200%)...
December 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29214776/14-3-3%C3%AE-overexpression-is-associated-with-poor-prognosis-in-ovarian-cancer
#20
Hyun Jung Kim, Sun Hee Sung, Chan Young Kim, Moon Kyoung Bae, Min Sun Cho, Yun Hwan Kim, Seung Cheol Kim, Woong Ju
PURPOSE: 14-3-3ζregulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role in ovarian cancer is unknown. Our goal was to investigate whether 14-3-3ζis associated with ovarian cancer prognosis. MATERIALS AND METHODS: We examined 14-3-3ζexpression by immunohistochemistry in ovarian cancer tissues obtained from 88 ovarian cancer patients...
January 2018: Yonsei Medical Journal
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