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Kate L McCarthy, Tim J Kidd, David L Paterson
PURPOSE: The molecular epidemiology of Pseudomonas aeruginosa bloodstream infection (BSI) isolates has received limited attention. This study aims to characterize the molecular relationship of P. aeruginosa BSI isolates in the non-outbreak setting at a single tertiary healthcare facility. METHODOLOGY:   P. aeruginosa BSI isolates from patients who were admitted to the Royal Brisbane and Women's Hospital over a 13 month period from November 2009 were identified retrospectively from the Pathology Queensland Clinical and Scientific Information System...
March 2017: Journal of Medical Microbiology
Michael A Neblo, William Minozzi, Kevin M Esterling, Jon Green, Jonathon Kingzette, David M J Lazer
No abstract text is available yet for this article.
March 3, 2017: Science
Ryan Kennedy, Stefan Wojcik, David Lazer
This study reports the results of a multiyear program to predict direct executive elections in a variety of countries from globally pooled data. We developed prediction models by means of an election data set covering 86 countries and more than 500 elections, and a separate data set with extensive polling data from 146 election rounds. We also participated in two live forecasting experiments. Our models correctly predicted 80 to 90% of elections in out-of-sample tests. The results suggest that global elections can be successfully modeled and that they are likely to become more predictable as more information becomes available in future elections...
February 3, 2017: Science
Michael Chaikof, Tal Lazer, Itai Gat, Kevin Quach, Basheer Alkudmani, Khaled Zohni, Ari Baratz, Karen Glass, Prati Sharma, Clifford Librach
BACKGROUND: Missed abortion (MA) can be managed expectantly, medically or surgically. Surgical management has been performed safely in the office setting by suction dilation and curettage (D&C). Prior studies suggest that intraoperative ultrasound guidance (USG) may reduce complications for first-trimester therapeutic abortion. The aim of this study was to evaluate the safety of office D&C for MA using real-time USG. METHODS: This retrospective cohort study included 255 patients who underwent office D&C under USG for first trimester MA at a single university-affiliated fertility clinic during January 2011-December 2013...
February 2017: Minerva Ginecologica
Manuela Ferreira Regis, Luciano Machado Ferreira Tenório de Oliveira, Ana Raquel Mendes Dos Santos, Ameliane da Conceição Reubens Leonidio, Paula Rejane Beserra Diniz, Clara Maria Silvestre Monteiro de Freitas
Objective: To analyze the levels of physical activity and sedentary behavior in adolescents living in urban and rural areas. Methods: An epidemiological, cross-section study with quantitative design, carried out at the regional level. The sample comprised 6,234 students aged 14 to 19 years, selected using random cluster sampling. The χ2 test and binary logistic regression were used in the analysis. Results: A total of 74.5% of adolescents lived in urban areas...
October 2016: Einstein
Wei Wang, Ryan Kennedy, David Lazer, Naren Ramakrishnan
No abstract text is available yet for this article.
September 30, 2016: Science
Karina Araujo Pinto, Greice Maria de Souza Menezes, Rosane Härter Griep, Keury Thaisana Rodrigues Dos Santos Lima, Maria da Conceição Almeida, Estela M L Aquino
In this study, we evaluated the psychometric properties of the items to measure the work-family conflict and the time use for personal care and leisure, included in the baseline questionnaire of the Longitudinal Study of Adult Health (ELSA-Brazil). We evaluated temporal stability (7-14 days) using kappa statistic and the validity of the construct by the correlation of Kendall's tau with other variables. Test-retest stability was discreet to moderate and the correlations were compatible with the underlying theory...
July 4, 2016: Revista de Saúde Pública
S Friedler, S Meltzer, B Saar-Ryss, J Rabinson, T Lazer, G Liberty
AIM: As no upper limit of the daily dose of gonadotropins (DD GN) used for controlled ovarian hyperstimulation (COH) in patients undergoing assisted reproductive technology (ART) has been established, we aimed to evaluate the efficacy of using different DD GN in terms of live-birth achievement. METHODS: Data of patients treated at a single university medical center during the same period was analyzed retrospectively. Four groups were analyzed according to the DD GN administered: group I ("high dose"):  >225- ≤ 375 IU; Group II ("Very high dose"): 376-450 IU; group III ("extremely high dose"): 451-600 IU...
December 2016: Gynecological Endocrinology
Monica C George, Zane P Lazer, David S George
UNLABELLED: We present a technique that uses a near-point string to demonstrate the anticipated near point of multifocal and accommodating intraocular lenses (IOLs). Beads are placed on the string at distances corresponding to the near points for diffractive and accommodating IOLs. The string is held up to the patient's eye to demonstrate where each of the IOLs is likely to provide the best near vision. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned...
May 2016: Journal of Cataract and Refractive Surgery
T Lazer, S Meltzer, B Saar-Ryss, G Liberty, Y Rabinson, S Friedler
OBJECTIVE: To evaluate the efficacy of selective salpingography and tubal canalization (TC) procedure among patients diagnosed with proximal tubal occlusion (PTO). METHODS: We conducted a retrospective cohort study on 61 sub-fertile patients aged 32.6 ± 4.9 years that were referred between the years of 2011 and 2013 with the diagnosis of PTO by prior hysterosalpingography. Patients underwent TC and were classified as bilateral PTO or unilateral PTO. Information regarding the patient's reproductive outcome within the 12 months following the procedure was collected by a telephone survey...
May 2016: Archives of Gynecology and Obstetrics
Eli S Neiman, Spozhmy Panezai, Sumaiya Salim, Michael Seyffert, Lazer E Leifer, Michael Rosenberg, Sudhansu Chokroverty
Anti-N-Methyl-D-Aspartate receptor encephalitis is a recently described entity (Dalmau et al. 2007, 2008) that may present with a variety of complex movements in addition to other features (Kleinig et al. 2008). The purpose of our presentation of such a patient is twofold: (1) to characterize these complex oculo-oro-linguo-masticatory and limb movements with "smooch sign" as myorhythmia, based on a combined clinical and electrophysiological analysis (Masucci et al. 1984); and (2) to document possibly characteristic EEG evolution in the course of observation in our institution for three weeks from diffuse slowing to evolving rhythmic delta activity, which may represent a pattern of electrographic seizure activity...
September 2015: Neurodiagnostic Journal
Sonia Mann, Ankita Sharma, Sagarika Biswas, Rajinder K Gupta
Underutilized plant species has started changing the conception of plants by expanding the use well beyond from foods and fibers to rich source of medicinally important secondary metabolites. Bioactive compounds from natural sources are gaining importance as potential drug candidates towards many inflammatory conditions like Rheumatoid Arthritis (RA). The focus of the present study has been centred to reveal the anti-inflammatory potential of an underutilized fruits of B. sapida. Further efforts towards its medicinal significance may provide relieve from symptoms of RA by reducing the side effects that are observed in available medications...
2015: Bioinformation
Gheona Altarescu, Rachel Beeri, Galit Lazer-Derbeko, Talia Eldar-Geva, Avraham Steinberg, Ephrat Levy-Lahad, Paul Renbaum
New technologies are revealing genetic variants of unknown significance (VUS), raising questions about the indications that call for preimplanation genetic diagnosis (PGD). Two couples requesting PGD for VUS are presented. The first couple requested PGD for Lynch syndrome. Whole exome sequencing identified in a healthy male with a family history of Lynch-associated tumours, a MLH1 missense variant. The variant had not been reported as pathogenic, but was predicted as damaging by algorithms. The second couple had a child diagnosed with pervasive developmental disorder and intellectual disability, carrying a microduplication on chr:Xp...
November 2015: Reproductive Biomedicine Online
Nan Cao, Yu-Ru Lin, Xiaohua Sun, D Lazer, Shixia Liu, Huamin Qu
When and where is an idea dispersed? Social media, like Twitter, has been increasingly used for exchanging information, opinions and emotions about events that are happening across the world. Here we propose a novel visualization design, "Whisper", for tracing the process of information diffusion in social media in real time. Our design highlights three major characteristics of diffusion processes in social media: the temporal trend, social-spatial extent, and community response of a topic of interest. Such social, spatiotemporal processes are conveyed based on a sunflower metaphor whose seeds are often dispersed far away...
December 2012: IEEE Transactions on Visualization and Computer Graphics
Lorena Katharina Hartmann, Verena Neubert, Katrin Luise Läzer, Peter Ackermann, Maria Schreiber, Tamara Fischmann, Marianne Leuzinger-Bohleber
No abstract text is available yet for this article.
June 2015: Journal of the American Psychoanalytic Association
Jameson L Toole, Yu-Ru Lin, Erich Muehlegger, Daniel Shoag, Marta C González, David Lazer
Can data from mobile phones be used to observe economic shocks and their consequences at multiple scales? Here we present novel methods to detect mass layoffs, identify individuals affected by them and predict changes in aggregate unemployment rates using call detail records (CDRs) from mobile phones. Using the closure of a large manufacturing plant as a case study, we first describe a structural break model to correctly detect the date of a mass layoff and estimate its size. We then use a Bayesian classification model to identify affected individuals by observing changes in calling behaviour following the plant's closure...
June 6, 2015: Journal of the Royal Society, Interface
David Lazer
No abstract text is available yet for this article.
June 5, 2015: Science
Shidong Zhang, Dongsheng Wang, Shuwei Dong, Feng Yang, Zuoting Yan
ETHNOPHARMACOLOGICAL RELEVANCE: Bai-Hu-Tang (BHT) has been traditionally used to clear heat and engender fluids. AIM OF THE STUDY: To reveal the alteration of differentially expressed genes (DEGs) between lipopolysaccharide (LPS) febrile syndrome in rabbits and treatment with BHT which is a classical anti-febrile formula in traditional Chinese medicine. MATERIALS AND METHODS: Febrile model was induced by LPS injection (i.v.) in rabbits, and BHT was gavaged to another group of febrile rabbits...
July 1, 2015: Journal of Ethnopharmacology
William Minozzi, Michael A Neblo, Kevin M Esterling, David M J Lazer
Do leaders persuade? Social scientists have long studied the relationship between elite behavior and mass opinion. However, there is surprisingly little evidence regarding direct persuasion by leaders. Here we show that political leaders can persuade their constituents directly on three dimensions: substantive attitudes regarding policy issues, attributions regarding the leaders' qualities, and subsequent voting behavior. We ran two randomized controlled field experiments testing the causal effects of directly interacting with a sitting politician...
March 31, 2015: Proceedings of the National Academy of Sciences of the United States of America
Tal Lazer, Shir Dar, Ekaterina Shlush, Basheer S Al Kudmani, Kevin Quach, Agata Sojecki, Karen Glass, Prati Sharma, Ari Baratz, Clifford L Librach
We examined whether treatment with minimum-dose stimulation (MS) protocol enhances clinical pregnancy rates compared to high-dose stimulation (HS) protocol. A retrospective cohort study was performed comparing IVF and pregnancy outcomes between MS and HS gonadotropin-antagonist protocol for patients with poor ovarian reserve (POR). Inclusion criteria included patients with an anti-Müllerian hormone (AMH) ≤8 pmol/L and/or antral follicle count (AFC) ≤5 on days 2-3 of the cycle. Patients from 2008 exclusively had a HS protocol treatment, while patients in 2010 had treatment with a MS protocol exclusively...
2014: International Journal of Reproductive Medicine
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