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https://www.readbyqxmd.com/read/21492998/cerebrospinal-fluid-eosinophilia-associated-with-intraventricular-shunts
#1
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Sofia Bezerra, Thomas More Frigeri, Carlos Marcelo Severo, João Carlos Batista Santana, Carlos Graeff-Teixeira
CSF eosinophilia (CSF-eo) is uncommon and is usually caused by helminthic infections. However, it has also been found in ∼30% of patients experiencing intraventricular shunt malfunctions. We present a case report and review the conditions associated with CSF-eo and their prophylaxis. An 8 year-old boy with tetraventricular hydrocephalus has had several shunt malfunctions over the last three years. During hospitalization in January 2009 for shunt revision, a transient 30% eosinophilia was detected in his cerebral spinal fluid (CSF) concomitant with Staphylococcus epidermidis infection and long term vancomycin administration...
June 2011: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/16038302/modeling-of-overloaded-gradient-elution-of-nociceptin-orphanin-fq-in-reversed-phase-liquid-chromatography
#2
Nicola Marchetti, Francesco Dondi, Attila Felinger, Remo Guerrini, Severo Salvadori, Alberto Cavazzini
The Reversed-phase (RP) gradient elution chromatography of nociceptin/orphanin FQ (N/OFQ), a neuropeptide with many biological effects, has been modeled under linear and non-linear conditions. In order to do this, the chromatographic behavior has been studied under both linear and nonliner conditions under isocratic mode at different mobile phase compositions--ranging from 16 to 19% (v/v) acetonitrile (ACN) in aqueous trifluoracetic acid (TFA) 0.1% (v/v)-on a C-8 column. Although the range of mobile phase compositions investigated was quite narrow, the retention factor of this relatively small polypeptide (N/OFQ is a heptadecapeptide) has been found to change by more than 400%...
June 24, 2005: Journal of Chromatography. A
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