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https://www.readbyqxmd.com/read/29231914/determinants-of-late-life-depression-in-residents-of-long-term-care-facility
#1
Urszula Horwath, Katarzyna Szczerbińska
Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF). Late-life depression refers to depressive symptoms that arise in adults older than 65 years. According to literature review, older people tend to differ from middle-aged adults in presentation of depression. AIM: Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF)...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29230700/disclosure-is-inadequate-as-a-solution-to-managing-conflicts-of-interest-in-human-research
#2
Helene Jacmon
Disclosure is a common response to conflicts of interest; it is intended to expose the conflict to scrutiny and enable it to be appropriately managed. For disclosure to be effective the receiver of the disclosure needs to be able to use the information to assess how the conflict may impact on their interests and then implement a suitable response. The act of disclosure also creates an expectation of self-regulation, as the person with the conflicting interests will be mindful of their own potential biases and aware that their decisions may be monitored...
December 11, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29230306/cultural-shift-in-mental-illness-a-comparison-of-stress-responses-in-world-war-i-and-the-vietnam-war
#3
Rasjid Skinner, Paul M Kaplick
Objectives: Post-traumatic stress disorder is an established diagnostic category. In particular, over the past 20 years, there has been an interest in culture as a fundamental factor in post-traumatic stress disorder symptom manifestation. However, only a very limited portion of this literature studies the historical variability of post-traumatic stress within a particular culture. Design: Therefore, this study examines whether stress responses to violence associated with armed conflicts have been a culturally stable reaction in Western troops...
December 2017: JRSM Open
https://www.readbyqxmd.com/read/29229044/the-commercialization-of-patient-related-decision-making-in-hospitals
#4
Karl-Heinz Wehkamp, Heinz Naegler
BACKGROUND: Hospitals must make a profit to ensure their continued existence. The observed rises in case numbers and case-mix indices lead us to suspect that the admission, treatment, and discharge of patients are now being influenced not just by purely medical factors, but also by economic considerations with a view toward making a profit-i.e., that decision-making has become partially commercialized. In this study, we investigated whether doctors and hospital chief executive officers (CEOs) share this perception of their professional environment...
November 24, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29228373/medical-treatment-or-surgery-for-colorectal-endometriosis-results-of-a-shared-decision-making-approach
#5
Paolo Vercellini, Maria Pina Frattaruolo, Riccardo Rosati, Dhouha Dridi, Anna Roberto, Paola Mosconi, Olga De Giorgi, Fulvia Milena Cribiù, Edgardo Somigliana
STUDY QUESTION: What is the degree of patient satisfaction in women with symptomatic colorectal endometriosis who choose medical or surgical treatment after a shared decision-making (SDM) process? SUMMARY ANSWER: The degree of satisfaction with treatment was high both in women who chose medical treatment with a low-dose oral contraceptive (OCP) or a progestin, and in those who chose to undergo surgical resection of bowel endometriosis. WHAT IS KNOWN ALREADY: Hormonal therapies and surgery for colorectal endometriosis have been investigated in non-comparative studies with inconsistent results...
December 8, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29220645/the-value-of-a-learning-needs-analysis-to-establish-educational-priorities-in-a-new-clinical-workforce
#6
Adrienne Hudson, Elayne Ellis-Cohen, Shari Davies, Desley Horn, Alison Dale, Lorelle Malyon, Rachel Edwards, Jane Harnischfeger, Glenda Radel, Rebecca Bundy, Jacqueline Jauncey-Cooke
A learning needs analysis was undertaken in a newly formed workforce. The goal of the learning needs analysis was to establish both the skill set and educational needs in the nursing workforce prior to moving to a new purpose built facility. The results would then enable nurse educators to develop, plan and deliver appropriate educational strategies. Staff (73%) completed an online survey; the results were collated and analysed. The results of the learning needs analysis suggested an experienced workforce that had great capacity to care for children across a wide spectrum of acute clinical needs...
November 27, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/29219798/-guideline-organ-donation-following-euthanasia
#7
H Mulder, G Olthuis, M Siebelink, R Gerritsen, E van Heurn
- The multidisciplinary guideline 'Organ donation following euthanasia' was published in March 2017 at request of the Minister of Health, Welfare and Sport.- This guideline provides recommendations for the organisation and implementation of a request to donate organs expressed by a patient who asks for euthanasia.- It is vital to avoid any conflict of interest while the patient requesting organ donation following euthanasia is still alive.- The person who carries out the euthanasia procedure is responsible for assessing the degree of unbearable suffering and for guaranteeing that potential organ donation is well-considered and voluntary...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29217466/influence-of-corticosterone-treatment-on-nestling-begging-in-florida-scrub-jays-aphelocoma-coerulescens
#8
Emily K Elderbrock, Thomas W Small, Stephan J Schoech
Altricial young are dependent on adults for protection and food, and they display nutritional need by begging to elicit feeding from parents. Begging at high levels can be energetically expensive and attract predators; thus, an individual must balance its nutritional needs with these potential costs. Further, because a parent is limited in the amount of food it can provide, begging can contribute to both parent-offspring conflict and sibling-sibling competition. Many extrinsic and intrinsic factors may contribute to begging behavior...
December 4, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29217464/the-relationship-between-trait-psychopathy-and-emotional-intelligence-a-meta-analytic-review
#9
REVIEW
A Megías, R Gómez-Leal, M J Gutiérrez-Cobo, R Cabello, P Fernández-Berrocal
Psychopathy is a personality construct that has been related to important emotional deficits. These findings have led to a growing interest in exploring if psychopathic traits are associated with emotional intelligence (EI). However, the literature exploring this association has revealed conflicting results. The aim of the present study was to provide a reliable estimate of the relationship between psychopathy traits and EI (measured as performance-based ability) through meta-analysis. A quantitative and systematic review of the literature using Scopus, Medline, Pubmed, and PsicINFO showed a total of 13 studies meeting inclusion criteria with a combined sample of 2401 participants...
December 4, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29215615/conflicts-of-interest-in-the-north-american-consensus-on-breath-testing
#10
Charles Maltz
No abstract text is available yet for this article.
December 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29215523/ethical-considerations-concerning-amnioinfusions-for-treating-fetal-bilateral-renal-agenesis
#11
Jeremy Sugarman, Jean Anderson, Ahmet A Baschat, Jaime Herrera Beutler, Jessica L Bienstock, Timothy E Bunchman, Niraj M Desai, Elena Gates, Aviva Goldberg, Paul C Grimm, Leslie Meltzer Henry, Eric B Jelin, Emily Johnson, Christine B Hertenstein, Anna C Mastroianni, Mark R Mercurio, Alicia Neu, Lawrence M Nogee, William J Polzin, Steven J Ralston, Ronald M Ramus, Megan Kasimatis Singleton, Michael J G Somers, Karen C Wang, Renee Boss
Congenital bilateral renal agenesis has been considered a uniformly fatal condition. However, the report of using serial amnioinfusions followed by the live birth in 2012 and ongoing survival of a child with bilateral renal agenesis has generated hope, but also considerable controversy over an array of complex clinical and ethical concerns. To assess the ethical concerns associated with using serial amnioinfusions for bilateral renal agenesis, we assembled a multidisciplinary group to map the ethical issues relevant to this novel intervention...
December 4, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29214363/correction-to-ibrutinib-does-not-prolong-the-corrected-qt-interval-in-healthy-subjects-results-from-a-thorough-qt-study
#12
Jan de Jong, Peter Hellemans, James Juhui Jiao, Yuhan Huang, Sofie Mesens, Juthamas Sukbuntherng, Daniele Ouellet
The author would like to correct the affiliations and conflict of interest in the publication of the original article. The corrected details are given below for your reading.
December 6, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/29211844/the-association-between-asthma-and-type-1-diabetes-a-paediatric-case-cohort-study-in-finland-years-1981-2009
#13
Johanna Metsälä, Annamari Lundqvist, Lauri J Virta, Minna Kaila, Mika Gissler, Suvi M Virtanen, Jaakko Nevalainen
Background: The association between asthma and type 1 diabetes, two chronic, immune-mediated diseases, has been of longstanding interest, but the evidence is still conflicting. We examined this association in a large, nationwide case-cohort study among Finnish children, using a novel statistical approach. Methods: Among the initial cohort of all children born between 1 January 1981 and 31 December 2008, those who were diagnosed with asthma (n = 81 473) or type 1 diabetes (n = 9541) up to age 16 years by the end of 2009 were identified from the Central Drug Register maintained by the Social Insurance Institution of Finland...
December 2, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29211842/maternal-age-at-birth-and-daughters-subsequent-childlessness
#14
O Basso, C R Weinberg, A A D'Aloisio, D P Sandler
STUDY QUESTION: Does maternal age at a daughter's birth predict her subsequent probability of lifelong childlessness? SUMMARY ANSWER: In this study population, women born to older mothers were more likely to be childless. WHAT IS KNOWN ALREADY: Although maternal age at childbearing is increasing in many countries, there is limited evidence on whether being born to older parents may influence offspring fertility. STUDY DESIGN SIZE AND DURATION: This analysis included 43 135 women from the US-based Sister Study, a cohort study of 50 884 sisters of women with breast cancer recruited between 2003 and 2009...
December 4, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29210755/recruitment-of-dual-career-academic-medicine-couples
#15
Charles W Putnam, Judy DiMarco, Charles B Cairns
Today it is not uncommon to discover that a candidate for a faculty position has a partner or spouse who is also an academician, adding complexity to the recruitment process. Here, the authors address two practical obstacles to the recruitment of faculty who have an academic partner: dual recruitment and conflict-of-interest. The authors have found that tandem recruitment works best when suitable positions for both spouses are first identified so that recruitment can proceed synchronously. This approach decreases misperceptions of favoritism toward either's candidacy...
November 28, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29210448/maternal-effects-and-parent-offspring-conflict
#16
Bram Kuijper, Rufus A Johnstone
Maternal effects can provide offspring with reliable information about the environment they are likely to experience, but also offer scope for maternal manipulation of young when interests diverge between parents and offspring. To predict the impact of parent-offspring conflict, we model the evolution of maternal effects on local adaptation of young. We find that parent-offspring conflict strongly influences the stability of maternal effects; moreover, the nature of the disagreement between parents and young predicts how conflict is resolved: when mothers favor less extreme mixtures of phenotypes relative to offspring (i...
December 6, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29210141/extending-addiction-s-conflict-of-interest-policy-to-cover-the-emerging-cannabis-industry
#17
EDITORIAL
Keith Humphreys, Shane Darke, John Marsden, Robert West
No abstract text is available yet for this article.
December 5, 2017: Addiction
https://www.readbyqxmd.com/read/29208054/unpublished-systematic-reviews-and-financial-support-a-meta-epidemiological-study
#18
Hiraku Tsujimoto, Yasushi Tsujimoto, Yuki Kataoka
OBJECTIVE: PROSPERO, an international prospective register of systematic reviews, was launched in February 2011 to reduce publication bias of systematic reviews (SRs). A questionnaire survey of SR researchers conducted in 2005 indicated the existence of unpublished SRs and the potential influence of lack of funding as a reason for non-publication. Here, we investigated the publication status of registered SRs in the 1st year that PROSPERO launched and assessed the association between publication and the existence of funding or conflicts of interest (COIs)...
December 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29206944/the-direct-and-indirect-effects-of-kisspeptin-54-on-granulosa-lutein-cell-function
#19
L A Owens, A Abbara, A Lerner, S O'floinn, G Christopoulos, S Khanjani, R Islam, K Hardy, A C Hanyaloglu, S A Lavery, W S Dhillo, S Franks
STUDY QUESTION: What are the in vivo and in vitro actions of kisspeptin-54 on the expression of genes involved in ovarian reproductive function, steroidogenesis and ovarian hyperstimulation syndrome (OHSS) in granulosa lutein (GL) cells when compared with traditional triggers of oocyte maturation? SUMMARY ANSWER: The use of kisspeptin-54 as an oocyte maturation trigger augmented expression of genes involved in ovarian steroidogenesis in human GL cells including, FSH receptor (FSHR), LH/hCG receptor (LHCGR), steroid acute regulatory protein (STAR), aromatase, estrogen receptors alpha and beta (ESR1, ESR2), 3-beta-hydroxysteroid dehydrogenase type 2 (3BHSD2) and inhibin A (INHBA), when compared to traditional maturation triggers, but did not alter markers of OHSS...
December 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29205437/mrna-traffic-control-reviewed-n6-methyladenosine-m6-a-takes-the-driver-s-seat
#20
REVIEW
Abhirami Visvanathan, Kumaravel Somasundaram
Messenger RNA is a flexible tool box that plays a key role in the dynamic regulation of gene expression. RNA modifications variegate the message conveyed by the mRNA. Similar to DNA and histone modifications, mRNA modifications are reversible and play a key role in the regulation of molecular events. Our understanding about the landscape of RNA modifications is still rudimentary in contrast to DNA and histone modifications. The major obstacle has been the lack of sensitive detection methods since they are non-editing events...
December 4, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
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