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Red skin syndrome

Zaw Min, Raquel R Garcia, Monika Murillo, Jeffrey M Uchin, Nitin Bhanot
Intravenous vancomycin is a widely used antibiotics, but it causes different types of cutaneous hypersensitivity reactions, ranging from maculopapular rash, red-man syndrome, drug rash with eosinophilia and systemic symptoms, IgA bullous dermatosis, leukocytoclastic vasculitis, Stevens-Johnsons syndrome, to IgE-mediated anaphylaxis. We report an elderly patient with the end-stage renal disease presented with diffuse palpable purpura while receiving IV vancomycin therapy for methicillin-resistant Staphylococcus aureus septicemia...
September 25, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
Dustin L Higashi, Nicolas Biais, Deborah L Donahue, Jeffrey A Mayfield, Charles R Tessier, Kevin Rodriguez, Brandon L Ashfeld, Jeffrey Luchetti, Victoria A Ploplis, Francis J Castellino, Shaun W Lee
Streptococcus pyogenes, or group A Streptococcus (GAS), is a human bacterial pathogen that can manifest as a range of diseases from pharyngitis and impetigo to severe outcomes such as necrotizing fasciitis and toxic shock syndrome. GAS disease remains a global health burden with cases estimated at over 700 million annually and over half a million deaths due to severe infections(1). For over 100 years, a clinical hallmark of diagnosis has been the appearance of complete (beta) haemolysis when grown in the presence of blood...
2016: Nature Microbiology
Y N Wang, J L Zhuang, W L Zhao, K Fang, Y H Liu, H Z Jin, L Li
OBJECTIVE: To study the clinical, histopathological and therapeutic features of Sweet syndrome with myelodysplastic syndrome (MDS). METHODS: The clinical data of 3 patients with Sweet syndrome and MDS diagnosed at Peking Union Medical College Hospital between October 1988 and November 2015 were reviewed. The laboratory test results, histopathological findings, and therapeutic regimens of these patients were analyzed retrospectively. RESULTS: The three cases were 29, 49 and 49 years old, respectively, including 2 females and 1 male...
June 14, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Wolfgang Hemmer, Christoph Klug, Ines Swoboda
Allergy to poultry meat is rare and affects both children and adults. The prevalence of poultry meat allergy is unknown, but presumably is similar to that of red meat allergy. There is no close relationship between allergy to poultry meat and allergy to red meat. Poultry meat allergy may present as primary (genuine) food allergy or as secondary food allergy resulting from cross-reactivity. Secondary poultry meat allergy may arise in the context of bird-egg-syndrome, which is due to sensitization to serum albumins present in many tissues including muscle tissue and egg yolk (Gal d 5)...
2016: Allergo Journal International
Seong-Ho Jin, Gyeongsin Park, Youngkyung Ko, Jun-Beom Park
The purpose of this report is to present a case of myeloid sarcoma of the gingiva with myelodysplastic syndrome.A 52-year-old male diagnosed with myelodysplastic syndrome with skin lesions presented with gingival swelling and gingival redness involving the maxillary left second premolar and the maxillary left first molar. The patient was referred from the Department of Hematology for a biopsy of the lesion. Full-thickness flaps were elevated and inflamed, and neoplastic soft tissue was removed from a lesion and the samples sent for histopathologic analysis...
June 2016: Medicine (Baltimore)
Mark Volpe
Sweet syndrome (acute febrile neutrophilic dermatosis) is an uncommon dermatologic eruption characterized by acute onset of painful papules, plaques or nodules on the skin that are red, blue, or violaceous in color. It has been associated with various infections, medications, and malignancies. Here we report the case of a middle-aged male who presents with Sweet syndrome after an upper resipiratory infection and while using amoxicillin. We also review the diagnostic criteria, laboratory testing, and treatment options...
2016: Curēus
Attila Oláh, Arnold Markovics, Judit Szabó-Papp, Pálma Tímea Szabó, Colin Stott, Christos C Zouboulis, Tamás Bíró
Acne is a common skin disease characterized by elevated sebum production and inflammation of the sebaceous glands. We have previously shown that a non-psychotropic phytocannabinoid ((-)-cannabidiol [CBD]) exerted complex anti-acne effects by normalizing 'pro-acne agents'-induced excessive sebaceous lipid production, reducing proliferation and alleviating inflammation in human SZ95 sebocytes. Therefore, in this study we aimed to explore the putative anti-acne effects of further non-psychotropic phytocannabinoids ((-)-cannabichromene [CBC], (-)-cannabidivarin [CBDV], (-)-cannabigerol [CBG], (-)-cannabigerovarin [CBGV] and (-)-Δ(9) -tetrahydrocannabivarin [THCV])...
September 2016: Experimental Dermatology
Evan Rieder, Marianna Shvartsbeyn, Shane A Meehan
Multiple cutaneous and uterine leiomyoma (MCL), or Reed syndrome is an uncommon condition that includes cutaneous piloleiomyomas and internal neoplasms of the uterus and kidney. Clinical findings include clusters of variably-painful, skin-colored-to-red-brown papules. Genetic testing shows germline mutations in the gene encoding fumarate hydratase. We describe a patient with MCL who presented with subtle cutaneous findings. We believe it is important that dermatologists consider a diagnosis of MCL when presented with patients with small painful dermal papules...
December 2015: Dermatology Online Journal
Carlos Sandoval, Jorge Infante, Jessica Abad, Hugh W Ferguson, Enrique Paredes, Samuel Valdebenito, Alejandro J Yáñez, Pedro Ilardi, Ruben Avendaño-Herrera
Strawberry disease is a chronic, nonlethal skin condition that affects Rainbow Trout Oncorhynchus mykiss in the United States and several European countries, where it is also known as red-mark syndrome. We provide the first identification and characterization of three strawberry disease outbreaks occurring at two aquaculture farms in southern Chile. Clinically affected fish weighing an average of 400 g presented multiple bright-red, usually raised, skin lesions on the flank, ventral surface, and dorsal surface...
March 2016: Journal of Aquatic Animal Health
Katherine J Ransohoff, Prajakta D Jaju, Prajaka D Jaju, Jean Y Tang, Michele Carbone, Sancy Leachman, Kavita Y Sarin
Phenotypic traits, such as red hair and freckling, increase melanoma risk by 2- to 3-fold. In addition, approximately 10% of melanomas are caused by inherited germline mutations that increase melanoma risk from 4- to >1000-fold. This review highlights the key genes responsible for inherited melanoma, with an emphasis on when a patient should undergo genetic testing. Many genetic syndromes associated with increased melanoma risk are also associated with an increased risk of other cancers. Identification of these high-risk patients is essential for preventive behavior reinforcement, genetic counseling, and ensuring other required cancer screenings...
March 2016: Journal of the American Academy of Dermatology
Virpi Elisa Raivio, Jenni Jonasson, Liisa Myllykangas, Sirpa Ala-Mello, Minna Kankuri-Tammilehto, Sari Kiuru-Enari, Per Westermark, Maarit Tanskanen, Tero Kivelä
OBJECTIVE: We describe a novel TTR mutation with vitreous opacities and carpal tunnel syndrome. MATERIALS AND METHODS: A 78 year-old woman with vitreous opacities, her daughter with dry eye syndrome, and brother with carpal tunnel syndrome were tested for a mutation in the TTR gene. The vitreous opacities were removed and stained with Congo red and immunohistochemistry against wild type TTR. Skin and gut biopsies and specimens of soft tissue were examined histopathologically...
2016: Amyloid: the International Journal of Experimental and Clinical Investigation
Moussa Abi Ghanem, Elie Saliba, Jihad Irani, Roula Darwish, Nadine Kawkabani, Toni Yared, Charbel Naim, Bassam Abu Khalil
BACKGROUND: Low molecular weight heparins are replacing unfractionated heparin in practice prior to cardiac surgery. This study examines postoperative (post-op) bleeding indicators in patients who received enoxaparin and underwent elective isolated first time coronary artery bypass graft. METHODS: A total of 125 consecutive patients who underwent this procedure between 2009 and 2011 at one tertiary center were reviewed and divided into three groups: Group A (n = 50) received the last dose of enoxaparin between 12 and 24 hours before surgery, Group B (n = 25) received the last dose before 24 hours and Group C (n = 50) did not receive enoxaparin...
October 2015: Le Journal Médical Libanais. the Lebanese Medical Journal
Ayako Okuno, Maiko Arao, Katsunori Aoki, Sayoko Yonemoto, Daisuke Hayashi, Naohiko Fujii, Kazumasa Oka
Here we report a rare case of Merkel cell carcinoma complicated with nephrosis and malignant lymphoma. A 79-year-old male, who had undergone rectectomy due to colorectal cancer about 10 years previously, was diagnosed as Merkel cell carcinoma of the left ear lobe with lymph node metastases. Tumor resection and lymph node dissection were performed. A year later, follow-up PET-CT revealed a small hot spot at the ileocecum without apparent tumor formation based on examination by colonoscopy. The patient received 56 Gy of radiation...
2015: Nihon Jinzo Gakkai Shi
Zdeněk Adam, Petr Szturz, Marta Krejčí, Vladimír Vašků, Luděk Pour, Eva Michalková, Sabina Ševčíková, Zdeňka Čermáková, Karel Veselý, Jíří Vaníček, Eva Pourová, Zdeněk Král, Jiří Mayer
INTRODUCTION: The mucinoses of the type of scleredema and scleromyxedema are diseases marked by excessive production of mucin deposits in the skin and subcutaneous tissue, which causes skin hardening. The skin and subcutaneous deposits hamper the movement of limbs, the thorax as well as mouth. The same mechanism also damages other organs (the heart, lungs, oesophagus). It is probably caused by the stimulation of mucin production in fibroblasts by immunoglobulins, frequently monoclonal immunoglobulin...
December 2015: Vnitr̆ní Lékar̆ství
Susan R Kahn, Jean-Philippe Galanaud, Suresh Vedantham, Jeffrey S Ginsberg
The post-thrombotic syndrome (PTS) is a frequent, potentially disabling complication of deep vein thrombosis (DVT) that reduces quality of life and is costly. Clinical manifestations include symptoms and signs such as leg pain and heaviness, edema, redness, telangiectasia, new varicose veins, hyperpigmentation, skin thickening and in severe cases, leg ulcers. The best way to prevent PTS is to prevent DVT with pharmacologic or mechanical thromboprophylaxis used in high risk patients and settings. In patients whose DVT is treated with a vitamin K antagonist, subtherapeutic INRs should be avoided...
January 2016: Journal of Thrombosis and Thrombolysis
N T Huong Giang, N T Lan, N H Nam, T Hirai, R Yamaguchi
In 2007, a highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) emerged in Vietnam and spread to nearly all regions of the country by 2010. Ten representative pigs of different age groups, infected naturally with HP-PRRSV in northern Vietnam in 2010, were used to characterize the pathological features of the infection. Infection was confirmed using reverse transcriptase polymerase chain reaction and viral isolation. The clinical signs and gross findings in these pigs included high fever (>40...
February 2016: Journal of Comparative Pathology
Diogo Diniz Gomes Bugano, Alexandre Biasi Cavalcanti, Anderson Roman Goncalves, Claudia Salvini de Almeida, Eliézer Silva
OBJECTIVE: To compare efficacy and safety of vancomycin versusteicoplanin in patients with proven or suspected infection. METHODS: HASH(0x4e53338) DATA SOURCES: Cochrane Renal Group's Specialized Register, CENTRAL, MEDLINE, EMBASE, nephrology textbooks and review articles. INCLUSION CRITERIA: Randomized controlled trials in any language comparing teicoplanin to vancomycin for patients with proven or suspected infection...
September 2011: Einstein
Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu, Guan J Liu
BACKGROUND: The morbidity and treatment costs associated with skin and soft tissue infections (SSTIs) are high. Linezolid and vancomycin are antibiotics that are commonly used in treating skin and soft-tissue infections, specifically those infections due to methicillin-resistant Staphylococcus aureus (MRSA). OBJECTIVES: To compare the effects and safety of linezolid and vancomycin for treating people with SSTIs. SEARCH METHODS: For this first update of this review we conducted searches of the following databases: Cochrane Wounds Group Specialised Register (searched 24 March 2015; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL...
2016: Cochrane Database of Systematic Reviews
Nada Zizi, Abdelhafid Elmrahi, Siham Dikhaye, Nadia Fihmi, Zayneb Alami
INTRODUCTION: Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening and severe adverse cutaneous drug reactions characterized by epidermal detachment presenting as blisters and areas of denuded skin. SJS, SJS-TEN overlap and TEN differ only by their extent of skin detachment. CASE PRESENTATION: We report here the case of a young woman (33- year old) admitted to the dermatological unit for epidermal detachment (at 18% of the body surface area), blisters, red macular and papular lesions, developed 15 days after administration of sulfasalazine...
July 2015: La Tunisie Médicale
C Hilger, J Fischer, K Swiontek, F Hentges, C Lehners, B Eberlein, M Morisset, T Biedermann, M Ollert
BACKGROUND: Serum IgE antibodies directed at galactose-α-1,3-galactose (α-Gal) are associated with a novel form of delayed anaphylaxis occurring upon consumption of red meat or innards. Pork kidney is known as the most potent trigger of this syndrome, but the culprit allergens have not yet been identified. The aim of this study was the identification and characterization of pork kidney proteins mediating delayed anaphylactic reactions through specific IgE to α-Gal. METHODS: A cohort of 59 patients with specific IgE to α-Gal was screened by immunoblot for IgE-reactive proteins in pork kidney...
May 2016: Allergy
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