D R Frei, R Beasley, D Campbell, A Forbes, K Leslie, D Mackle, C Martin, A Merry, M R Moore, P S Myles, L Ruawai-Hamilton, T G Short, P J Young
International recommendations encourage liberal administration of oxygen to patients having surgery under general anaesthesia, ostensibly to reduce surgical site infection. However, the optimal oxygen regimen to minimise postoperative complications and enhance recovery from surgery remains uncertain. The hospital operating theatre randomised oxygen (HOT-ROX) trial is a multicentre, patient- and assessor-blinded, parallel-group, randomised clinical trial designed to assess the effect of a restricted, standard care, or liberal peri-operative oxygen therapy regimen on days alive and at home after surgery in adults undergoing prolonged non-cardiac surgery under general anaesthesia...
August 2, 2023: Anaesthesia