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Colorectal polypectomy

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https://www.readbyqxmd.com/read/28212588/colorectal-polypectomy-and-endoscopic-mucosal-resection-emr-european-society-of-gastrointestinal-endoscopy-esge-clinical-guideline
#1
Monika Ferlitsch, Alan Moss, Cesare Hassan, Pradeep Bhandari, Jean-Marc Dumonceau, Gregorios Paspatis, Rodrigo Jover, Cord Langner, Maxime Bronzwaer, Kumanan Nalankilli, Paul Fockens, Rawi Hazzan, Ian M Gralnek, Michael Gschwantler, Elisabeth Waldmann, Philip Jeschek, Daniela Penz, Denis Heresbach, Leon Moons, Arnaud Lemmers, Konstantina Paraskeva, Juergen Pohl, Thierry Ponchon, Jaroslaw Regula, Alessandro Repici, Matthew D Rutter, Nicholas G Burgess, Michael J Bourke
1 ESGE recommends cold snare polypectomy (CSP) as the preferred technique for removal of diminutive polyps (size ≤ 5 mm). This technique has high rates of complete resection, adequate tissue sampling for histology, and low complication rates. (High quality evidence, strong recommendation.) 2 ESGE suggests CSP for sessile polyps 6 - 9 mm in size because of its superior safety profile, although evidence comparing efficacy with hot snare polypectomy (HSP) is lacking. (Moderate quality evidence, weak recommendation...
February 17, 2017: Endoscopy
https://www.readbyqxmd.com/read/28210856/the-effect-of-metformin-on-the-recurrence-of-colorectal-adenoma-in-diabetic-patients-with-previous-colorectal-adenoma
#2
Min Seok Han, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
PURPOSE: Existing studies suggest that metformin lowers the risk and mortality of colorectal cancer. However, the effect of metformin on the suppression and prevention of colorectal adenomas is not clear. The aim of this study was to evaluate the effect of metformin on the recurrence of colorectal adenoma in diabetic patients with previous colorectal adenoma. METHODS: Among 423 diabetic patients who underwent surveillance colonoscopy after resection of colorectal adenoma between 2005 and 2011, 257 patients were retrospectively reviewed...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28209333/green-tea-extracts-for-the-prevention-of-metachronous-colorectal-polyps-among-patients-who-underwent-endoscopic-removal-of-colorectal-adenomas-a-randomized-clinical-trial
#3
Cheol Min Shin, Dong Ho Lee, A Young Seo, Hyun Joo Lee, Seong Beom Kim, Woo-Chan Son, Young Kyung Kim, Sang Jun Lee, Sung-Hee Park, Nayoung Kim, Young Soo Park, Hyuk Yoon
OBJECTIVES: To determine the preventive effect of green tea extract (GTE) supplements on metachronous colorectal adenoma and cancer in the Korean population. MATERIALS AND METHODS: One hundred seventy-six subjects (88 per each group) who had undergone complete removal of colorectal adenomas by endoscopic polypectomy were enrolled. They were randomized into 2 groups: supplementation group (0.9 g GTE per day for 12 months) or control group without GTE supplementation...
January 29, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28192823/incomplete-resection-rate-of-cold-snare-polypectomy-a-prospective-single-arm-observational-study
#4
Noriko Matsuura, Yoji Takeuchi, Takeshi Yamashina, Takashi Ito, Kenji Aoi, Kengo Nagai, Takashi Kanesaka, Fumi Matsui, Mototsugu Fujii, Tomofumi Akasaka, Noboru Hanaoka, Koji Higashino, Yasuhiko Tomita, Yuri Ito, Ryu Ishihara, Hiroyasu Iishi, Noriya Uedo
Background and study aims Cold snare polypectomy (CSP) is considered to be safe for the removal of subcentimeter colorectal polyps. This study aimed to determine the rate of incomplete CSP resection for subcentimeter neoplastic polyps at our center. Patients and methods Patients with small or diminutive adenomas (diameter 1 - 9 mm) were recruited to undergo CSP until no polyp was visible. After CSP, a 1 - 3 mm margin around the resection site was removed using endoscopic mucosal resection. The polyps and resection site marginal specimens were microscopically evaluated...
February 13, 2017: Endoscopy
https://www.readbyqxmd.com/read/28161819/optimizing-resection-of-large-colorectal-polyps
#5
REVIEW
Steven J Heitman, David J Tate, Michael J Bourke
Polypectomy reduces the incidence and mortality of colorectal cancer (CRC). The widespread adoption of CRC screening, more rigorous colonoscopy techniques, and advancements in endoscopic imaging have led to a greater awareness of complex polyps. Whereas surgery was once considered necessary for many large sessile or laterally spreading lesions (LSLs) in the colorectum, the majority can now be removed endoscopically. Endoscopic mucosal resection (EMR) is an established technique for treatment of colorectal LSLs...
February 4, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28160332/histopathological-analysis-of-cold-snare-polypectomy-and-its-indication-for-colorectal-polyps-10-14mm-in-diameter
#6
Ryohei Hirose, Naohisa Yoshida, Takaaki Murakami, Kiyoshi Ogiso, Yutaka Inada, Osamu Dohi, Tetsuya Okayama, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Takeshi Ishikawa, Hideyuki Konishi, Yuji Naito, Yasuko Fujita, Mitsuo Kishimoto, Akio Yanagisawa, Yoshito Itoh
BACKGROUND AND AIM: Cold snare polypectomy (CSP) is commonly used for treating colorectal polyps <10 mm in diameter. We evaluated the histopathological and safety of CSP for larger polyps. METHODS: We retrospectively analyzed 1,006 colorectal polyps resected with CSP. The indication for CSP was polyps 2-14 mm that were diagnosed as benign neoplastic polyp by magnifying endoscopy. Various clinicopathological characteristics were analyzed. Multivariate analyses were utilized to determine the independent risk factors for failure of complete CSP resection...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28134634/delayed-bleeding-following-cold-snare-polypectomy-for-small-colorectal-polyps-in-patients-taking-antithrombotic-agents
#7
Toshiyuki Makino, Akira Horiuchi, Masashi Kajiyama, Naoki Tanaka, Kenji Sano, Iruru Maetani
BACKGROUND: This study compared the incidence of delayed bleeding following 2 methods of cold snare polypectomy for colorectal polyps in patients taking antithrombotic agents. METHODS: Patients undergoing cold snare polypectomy for colorectal polyps ≤10 mm without discontinuation of antithrombotic agents were enrolled. This was a retrospective study of a prospectively collected cohort based on a historical comparison of 2 time periods. A traditional cold snare was used between January 2012 and December 2013 and a dedicated cold snare was used between January 2014 and December 2015...
January 27, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28133246/-a-family-with-peutz-jeghers-syndrome-having-various-malignant-diseases
#8
Toshiro Ogura, Toru Ishiguro, Yu Muta, Minoru Fukuchi, Tomonori Nagai, Youichi Kumagai, Keiichiro Ishibashi, Erito Mochiki, Hideyuki Ishida
We report a 27-year-old female who was diagnosed with adenocarcinoma of the uterine cervix associated with Peutz- Jeghers syndrome(PJS). She had undergone 5 surgeries for intestinal intussusception and had been diagnosed with PJS. She was referred to our hospital, complaining of watery vaginal discharge, and was diagnosed with adenocarcinoma of the uterine cervix. Following neoadjuvant chemotherapy, radical hysterectomy and small intestinal polypectomy by intraoperative endoscopy were performed. Among the third-degree relatives of her family, 10 had been diagnosed with PJS; of these 10, uterine cervical adenocarcinoma occurred in 3 relatives, pancreatic cancer in 2, cholangiocellular carcinoma in 1, and colon cancer in 1...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28127206/removal-of-diminutive-colorectal-polyps-a-prospective-randomized-clinical-trial-between-cold-snare-polypectomy-and-hot-forceps-biopsy
#9
Yoriaki Komeda, Hiroshi Kashida, Toshiharu Sakurai, George Tribonias, Kazuki Okamoto, Masashi Kono, Mitsunari Yamada, Teppei Adachi, Hiromasa Mine, Tomoyuki Nagai, Yutaka Asakuma, Satoru Hagiwara, Shigenaga Matsui, Tomohiro Watanabe, Masayuki Kitano, Takaaki Chikugo, Yasutaka Chiba, Masatoshi Kudo
AIM: To compare the efficacy and safety of cold snare polypectomy (CSP) and hot forceps biopsy (HFB) for diminutive colorectal polyps. METHODS: This prospective, randomized single-center clinical trial included consecutive patients ≥ 20 years of age with diminutive colorectal polyps 3-5 mm from December 2014 to October 2015. The primary outcome measures were en-bloc resection (endoscopic evaluation) and complete resection rates (pathological evaluation). The secondary outcome measures were the immediate bleeding or immediate perforation rate after polypectomy, delayed bleeding or delayed perforation rate after polypectomy, use of clipping for bleeding or perforation, and polyp retrieval rate...
January 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28114040/automatic-detection-and-classification-of-colorectal-polyps-by-transferring-low-level-cnn-features-from-nonmedical-domain
#10
Ruikai Zhang, Yali Zheng, Tony Wing Chung Mak, Ruoxi Yu, Sunny H Wong, James Y W Lau, Carmen C Y Poon
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Although polypectomy at early stage reduces CRC incidence, 90% of the polyps are small and diminutive, where removal of them poses risks to patients that may outweigh the benefits. Correctly detecting and predicting polyp type during colonoscopy allows endoscopists to resect and discard the tissue without submitting it for histology, saving time, and costs. Nevertheless, human visual observation of early stage polyps varies. Therefore, this paper aims at developing a fully automatic algorithm to detect and classify hyperplastic and adenomatous colorectal polyps...
January 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28113800/computer-aided-classification-of-gastrointestinal-lesions-in-regular-colonoscopy
#11
Pablo Mesejo, Daniel Pizarro, Armand Abergel, Olivier Rouquette, Sylvain Beorchia, Laurent Poincloux, Adrien Bartoli
We have developed a technique to study how good computers can be at diagnosing gastrointestinal lesions from regular (white light and narrow banded) colonoscopic videos compared to two levels of clinical knowledge (expert and beginner). Our technique includes a novel tissue classification approach which may save clinician's time by avoiding chromoendoscopy, a time-consuming staining procedure using indigo carmine. Our technique also discriminates the severity of individual lesions in patients with many polyps, so that the gastroenterologist can directly focus on those requiring polypectomy...
March 29, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28111691/colorectal-cancer-screening
#12
Pak Wo Webber Chan, Jing Hieng Ngu, Zhongxian Poh, Roy Soetikno
Colorectal cancer, which is the leading cancer in Singapore, can be prevented by increased use of screening and polypectomy. A range of screening strategies such as stool-based tests, flexible sigmoidoscopy, colonoscopy and computed tomography colonography are available, each with different strengths and limitations. Primary care physicians should discuss appropriate screening modalities with their patients, tailored to their individual needs. Physicians, patients and the government should work in partnership to improve uptake of colorectal cancer screening to reduce the morbidity and mortality from colorectal cancer...
January 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28042387/colorectal-cancer-screening-opportunities-to-improve-uptake-outcomes-and-disparities
#13
REVIEW
Neal Shahidi, Winson Y Cheung
Colorectal cancer screening has become a standard of care in industrialized nations for those 50 to 75 years of age, along with selected high-risk populations. While colorectal cancer screening has been shown to reduce both the incidence and mortality of colorectal cancer, it is a complex multi-disciplinary process with a number of important steps that require optimization before tangible improvements in outcomes are possible. For both opportunistic and programmatic colorectal cancer screening, poor participant uptake remains an ongoing concern...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28035253/colon-adenoma-features-and-their-impact-on-risk-of-future-advanced-adenomas-and-colorectal-cancer
#14
Audrey H Calderwood, Karen E Lasser, Hemant K Roy
AIM: To review the evidence on the association between specific colon adenoma features and the risk of future colonic neoplasia [adenomas and colorectal cancer (CRC)]. METHODS: We performed a literature search using the National Library of Medicine through PubMed from 1/1/2003 to 5/30/2015. Specific Medical Subject Headings terms (colon, colon polyps, adenomatous polyps, epidemiology, natural history, growth, cancer screening, colonoscopy, CRC) were used in conjunction with subject headings/key words (surveillance, adenoma surveillance, polypectomy surveillance, and serrated adenoma)...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28024986/natural-history-of-diminutive-and-small-colorectal-polyps-a%C3%A2-systematic-literature-review
#15
REVIEW
Jasper L A Vleugels, Yark Hazewinkel, Paul Fockens, Evelien Dekker
BACKGROUND AND AIMS: Diminutive (1-5 mm) and small (6-9 mm) polyps comprise 90% of detected lesions during colonoscopy and rarely contain advanced histology or colorectal cancer (CRC). Routine removal of these lesions results in a significant burden to colonoscopy programs. At the same time, the risk for progression of these polyps to CRC is unclear. We performed a systematic review to explore the natural history of diminutive and small colorectal polyps. METHODS: We searched MEDLINE and EMBASE for studies investigating the natural history of colorectal polyps...
December 23, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28005009/computer-aided-classification-of-gastrointestinal-lesions-in-regular-colonoscopy
#16
Pablo Mesejo, Daniel Pizarro, Armand Abergel, Olivier Rouquette, Sylvain Beorchia, Laurent Poincloux, Adrien Bartoli
We have developed a technique to study how good computers can be at diagnosing gastrointestinal lesions from regular (white light and narrow banded) colonoscopic videos compared to two levels of clinical knowledge (expert and beginner). Our technique includes a novel tissue classification approach which may save clinician's time by avoiding chromoendoscopy, a time-consuming staining procedure using indigo carmine. Our technique also discriminates the severity of individual lesions in patients with many polyps, so that the gastroenterologist can directly focus on those requiring polypectomy...
September 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27988288/prospective-multicenter-randomized-controlled-trial-comparing-adenoma-detection-rate-in-colonoscopy-using-water-exchange-water-immersion-and-air-insufflation
#17
Yu-Hsi Hsieh, Chih-Wei Tseng, Chi-Tan Hu, Malcolm Koo, Felix W Leung
BACKGROUND AND AIMS: Adenoma detection rate (ADR), defined as the proportion of patients with at least one adenoma of any size, is a quality indicator. We tested the hypothesis that water exchange (WE) improves ADR but water immersion (WI) has no adverse effect on ADR compared with air insufflation (AI). METHODS: A prospective study was conducted at the Dalin Tzu Chi Hospital in southern Taiwan and the Hualien Tzu Chi Hospital in eastern Taiwan on patients randomly assigned to WE, WI, or AI with stratification by the 3 study colonoscopists...
December 15, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27987015/insulated-tip-knife-endoscopic-polypectomy-for-difficult-pedunculated-colorectal-polyps-a-prospective-pilot-study
#18
Lianjun Ma, Yaqi Zhai, Ningli Chai, Huikai Li, Li Yan, Zhenjuan Li, Xiaobin Zhang, Xiuxue Feng, Enqiang Linghu
BACKGROUND: Endoscopic polypectomy is widely used for colorectal polyps. However, for giant pedunculated colorectal polyps (≥3 cm), conventional techniques are so difficult with en bloc resection that patients had to be transferred to surgery. We had firstly reported our first experience with an insulated-tip knife to successfully remove a giant pedunculated polyp in the sigmoid colon. In this study, our aim was to explore safety and feasible of insulated-tip knife endoscopic polypectomy (IT-EP) for difficult pedunculated colorectal polyps...
February 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27888868/novel-findings-in-colorectal-polyp-surveillance
#19
Sabela Carballal
Colorectal adenomas and serrated polyps are the best characterised premalignant lesions involved in the development of colorectal cancer (CRC). Therefore, the identification and removal of these lesions, as well as post-polypectomy surveillance of affected patients, are key goals in the field of CRC prevention. Current post-polypectomy surveillance strategies differ among the various scientific societies and have several limitations that hamper their application in clinical practice. First, current surveillance intervals are based only on polyp characteristics, excluding other potential clinical conditions, such as diabetes or metabolic syndrome...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27881836/relationship-between-lesions-in-adenomatous-polyp-dysplasia-colorectal-cancer-sequence-and-neutrophil-to-lymphocyte-ratio
#20
Feyzullah Uçmak, Elif Tuğba Tuncel
BACKGROUND The aim of our study was to evaluate all lesions in the adenoma-dysplasia-cancer sequence of the colon and to examine whether the neutrophil-to-lymphocyte ratio (NLR) can distinguish polyps indicating dysplasia and cancer. MATERIAL AND METHODS A total of 397 patients who had colonoscopic polypectomy between January 2010 and December 2014 were included in our retrospective study. The patients were divided into four groups: patients with hyperplastic polyps, patients with adenomatous polyps, patients with dysplasia, and patients with cancer...
November 24, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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