keyword
https://read.qxmd.com/read/38006226/aneurysm-associated-with-vascular-wall-degeneration-in-bearded-dragons-pogona-vitticeps
#1
JOURNAL ARTICLE
Joaquín Ortega, Jeanette Wyneken, Michael M Garner
This study describes the clinical, gross, and histologic findings in 17 cases of aneurysms in bearded dragons ( Pogona vitticeps ). The clinical presentation ranged from incidental to sudden and unexpected death. The affected vasculature was predominantly arterial; however, based on the topographical locations of the lesions, gross structure, and drainage, some veins were likely involved. Magnetic resonance imaging and computerized tomography scans of 1 animal showed a large aneurysm of the internal carotid artery extending from near its aortic origin into the caudal head...
November 25, 2023: Veterinary Pathology
https://read.qxmd.com/read/37810738/validating-human-and-mouse-tissues-commonly-used-in-atherosclerosis-research-with-coronary-and-aortic-reference-tissue-similarities-but-profound-differences-in-disease-initiation-and-plaque-stability
#2
JOURNAL ARTICLE
Rogier A van Dijk, Robert Kleemann, Alexander F Schaapherder, Antoon van den Bogaerdt, Ulf Hedin, Ljubica Matic, Jan H N Lindeman
OBJECTIVE: Characterization of the atherosclerotic process fully relies on histological evaluation and staging through a consensus grading system. So far, a head-to-head comparison of atherosclerotic process in experimental models and tissue resources commonly applied in atherosclerosis research with the actual human atherosclerotic process is missing. MATERIAL AND METHODS: Aspects of the atherosclerotic process present in established murine atherosclerosis models and human carotid endarterectomy specimen were systematically graded using the modified American Heart Association histological classification (Virmani classification)...
2023: Journal of vascular surgery. Vascular science
https://read.qxmd.com/read/35819840/lipoprotein-subfractions-and-subclinical-vascular-health-in-middle-aged-women-does-menopause-status-matter
#3
JOURNAL ARTICLE
Meiyuzhen Qi, Xirun Chen, Ronald M Krauss, Karen Matthews, Imke Janssen, Maria M Brooks, Dan McConnell, Sybil L Crawford, Samar R El Khoudary
OBJECTIVE: During midlife, women experience changes in lipoprotein profiles and deterioration in vascular health measures. We analyzed the associations of groups of lipoprotein subfractions as determined by principal component analysis (PCA) with subclinical vascular health measures in midlife women and tested if these associations were modified by menopause status. METHODS: PCA was used to generate principal components (PCs) from 12 lipoprotein subfractions quantified among 545 midlife women...
July 12, 2022: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/35511059/new-strategy-of-using-double-network-hydrogel-extravascular-stent-for-preventing-venous-graft-restenosis-after-coronary-artery-bypass-grafting
#4
JOURNAL ARTICLE
Longsheng Dai, Wenyuan Yu, Yang Yu
OBJECTIVE: Effective therapies for the prevention of vein graft failure, which frequently occurs in coronary artery bypass grafting (CABG) due to intimal hyperplasia (IH), are still lacking. Here, we investigated the effects of the perivenous application of double-network hydrogel on vein grafts in carotid artery bypass grafting in a rabbit model. METHODS: Healthy New Zealand white rabbits were randomized into the following groups: no graft, graft, or graft + Double-network hydrogel external stent (DNHES)...
May 5, 2022: Perfusion
https://read.qxmd.com/read/35479275/clinical-use-of-hydrogen-sulfide-to-protect-against-intimal-hyperplasia
#5
REVIEW
Diane Macabrey, Alban Longchamp, Sébastien Déglise, Florent Allagnat
Arterial occlusive disease is the narrowing of the arteries via atherosclerotic plaque buildup. The major risk factors for arterial occlusive disease are age, high levels of cholesterol and triglycerides, diabetes, high blood pressure, and smoking. Arterial occlusive disease is the leading cause of death in Western countries. Patients who suffer from arterial occlusive disease develop peripheral arterial disease (PAD) when the narrowing affects limbs, stroke when the narrowing affects carotid arteries, and heart disease when the narrowing affects coronary arteries...
2022: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/34463897/the-effects-of-long-term-high-water-iodine-levels-in-the-external-environment-on-the-carotid-artery
#6
JOURNAL ARTICLE
Ji Bian, Man Zhang, Feng Li, Jie Gao, Zhexue Wei, Zijing Liu, Xiaoming Wang, Wen Jiang, Jianchao Bian
Iodine excess typically affects thyroid function in the human body and may damage carotid artery. Four investigation plots with different water iodine levels were selected in Shandong Province, China. These included a low, medium, and high iodine group and an iodine excess group whose water iodine content was < 10, 50-150, 150-300, and > 300 μg/L, respectively. Residents aged 20-65 years answered a questionnaire and underwent carotid artery ultrasonography, and their height, weight, and urinary iodine concentrations were measured...
August 31, 2021: Biological Trace Element Research
https://read.qxmd.com/read/34098671/-study-on-the-effect-of-antibiotics-application-in-perioperative-period-on-carotid-artery-and-serum-interleukin-6-in-periodontitis-rats-with-hyperlipidemia-or-diabetes
#7
JOURNAL ARTICLE
C Wang, H Li, Y Zhao, R Cheng, X X Shi, J H Gao, X Y Ren
Objective: To investigate the effect of antibiotics application in perioperative period on carotid artery and serum interluekin-6 (IL-6) in chronic periodontitis (CP) rats with hyperlipidemia (HL) or diabetes mellitus (DM). Methods: The models of CP rats with HL or DM were established in different batches. The rats were divided into groups as follows: A and A' were normal control groups, n =7 in each group; B(HL) and B'(DM) were groups of HL and DM, n =7 in each; C(HL+CP) and C'(DM+CP) were groups of CP with HL and CP with DM, n =21 in each...
June 9, 2021: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://read.qxmd.com/read/33730327/disease-relevant-single-cell-photonic-signatures-identify-s100%C3%AE-stem-cells-and-their-myogenic-progeny-in-vascular-lesions
#8
JOURNAL ARTICLE
Claire Molony, Damien King, Mariana Di Luca, Michael Kitching, Abidemi Olayinka, Roya Hakimjavadi, Lourdes A N Julius, Emma Fitzpatrick, Yusof Gusti, Denise Burtenshaw, Killian Healy, Emma K Finlay, David Kernan, Andreu Llobera, Weimin Liu, David Morrow, Eileen M Redmond, Jens Ducrée, Paul A Cahill
A hallmark of subclinical atherosclerosis is the accumulation of vascular smooth muscle cell (SMC)-like cells leading to intimal thickening and lesion formation. While medial SMCs contribute to vascular lesions, the involvement of resident vascular stem cells (vSCs) remains unclear. We evaluated single cell photonics as a discriminator of cell phenotype in vitro before the presence of vSC within vascular lesions was assessed ex vivo using supervised machine learning and further validated using lineage tracing analysis...
October 2021: Stem cell reviews and reports
https://read.qxmd.com/read/33433789/osteocalcin-and-vascular-calcification-in-hemodialysis-patients-an-observational-cohort-study
#9
JOURNAL ARTICLE
Hesham Kamal Habeeb Keryakos, Nagwa Ismail Okaily, Mariam Asaad Yacoub Boulis, Ahmed Mohamed Saadeldin Salama
BACKGROUND: Vascular calcification contributes to morbidity and mortality in patients with ESRD on maintenance hemodialysis. AIMS: To study the relationship between osteocalcin and vascular calcification. METHODS: 160 patients with ESRD on maintenance hemodialysis and 60 age-and sex-matched healthy controls were recruited. Serum vitamin K2 and osteocalcin both intact and undercarboxylated were measured. Transthoracic echocardiography was done for valvular calcification and thickening, and carotid duplex was done for carotid intimal medial calcification and thickening...
May 2021: International Urology and Nephrology
https://read.qxmd.com/read/33113405/association-between-neutrophil-to-lymphocyte-ratio-and-carotid-artery-wall-thickness-in-healthy-pregnant-women
#10
JOURNAL ARTICLE
Andrea Sonaglioni, Valentina Esposito, Chiara Caruso, Gian Luigi Nicolosi, Stefano Bianchi, Michele Lombardo, Gian Franco Gensini, Giuseppe Ambrosio
OBJECTIVE: Pregnancy may elicit a state of mild inflammation that might affect, either directly or indirectly, haematological parameters associated with systemic inflammation. In particular, both Neutrophil-to-lymphocyte ratio (NLR) and Red blood cells Distribution Width (RDW) have been found to be elevated in complicated pregnancy. However, data regarding the association of these haematological parameters with common carotid artery (CCA) intima-media thickness (IMT) in healthy pregnancy are scanty...
December 2020: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/32558228/percutaneous-endovascular-delivery-of-calcium-chloride-to-the-intact-porcine-carotid-artery-a-novel-animal-model-of-arterial-calcification
#11
JOURNAL ARTICLE
Sérgio R Abrão, Carlos M Campos, Rafael Cavalcante, Jeroen Eggermont, Pedro Lemos, Alex Lederman, Erasmo S da Silva, Ricardo Aun, Sergio Q Belczak, Alexandre Abizaid, Fabio Sandoli de Brito
OBJECTIVE: The present study evaluated the effect of endovascular administration of calcium chloride to the carotid artery of swines, to create a model of arterial calcification. METHODS: Fifteen Large White pigs were used for the study. Via endovascular treatment, carotid arteries were exposed during 9 min to either calcium chloride (experimental artery) or saline (control artery) with the use of the TAPAS catheter. Intravascular ultrasound (IVUS) imaging was obtained at baseline, postprocedure and at 30 days...
June 19, 2020: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/31738316/interactive-relations-across-dimensions-of-interpersonal-level-discrimination-and-depressive-symptoms-to-carotid-intimal-medial-thickening-in-african-americans
#12
JOURNAL ARTICLE
Danielle L Beatty Moody, Daniel K Leibel, Elizabeth J Pantesco, Carrington R Wendell, Shari R Waldstein, Michele K Evans, Alan B Zonderman
OBJECTIVE: To examine within-race interactions of multiple dimensions of self-reported discrimination with depressive symptoms in relation to carotid intimal-medial thickness (IMT), a subclinical marker of atherosclerosis prospectively implicated in stroke incidence, in middle-age to older African American and White adults. METHODS: Participants were a socioeconomically diverse group of 1,941 African Americans (56.5%) and Whites from the Healthy Aging in Neighborhoods of Diversity across the Life Span study (HANDLS; 30-64 years old, 47% men, 45...
November 13, 2019: Psychosomatic Medicine
https://read.qxmd.com/read/31470852/mfg-e8-mediates-arterial-aging-by-promoting-the-proinflammatory-phenotype-of-vascular-smooth-muscle-cells
#13
JOURNAL ARTICLE
Hou-Yu Chiang, Pao-Hsien Chu, Ting-Hein Lee
BACKGROUND: Among older adults, arterial aging is the major factor contributing to increased risk for cardiovascular disease-related morbidity and mortality. The chronic vascular inflammation that accompanies aging causes diffuse intimal-medial thickening of the arterial wall, thus increasing the vulnerability of aged vessels to vascular insults. Milk fat globule-epidermal growth factor 8 (MFG-E8) is a biomarker for aging arteries. This integrin-binding glycoprotein, induced by angiotensin II, facilitates vascular smooth muscle cell (VSMC) proliferation and invasion in aging vasculatures...
August 30, 2019: Journal of Biomedical Science
https://read.qxmd.com/read/31133497/association-of-serum-proprotein-convertase-subtilisin-kexin-type-9-with-early-atherosclerosis-in-newly-diagnosed-type-2-diabetes-mellitus
#14
JOURNAL ARTICLE
Wen Guo, Yingyun Gong, Jie Li, Pei Qin, Jing Lu, Xiaona Li, Wenfang Zhu, Nianzhen Xu, Hongwen Zhou, Qun Zhang
BACKGROUND AND AIM: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is rapidly gaining attention as a potential risk of developing atherosclerosis due to its crucial role in the regulation of low-density lipoprotein cholesterol (LDL-C) metabolism. The present study investigated the relationship between serum PCSK9 levels and early atherosclerosis as assessed by carotid intimal-medial thickness (CIMT) and brachial-ankle pulse wave velocity (ba-PWV) in newly diagnosed type 2 diabetes mellitus (T2DM)...
April 24, 2019: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://read.qxmd.com/read/30987675/study-of-mri-brain-findings-and-carotid-us-features-in-systemic-sclerosis-patients-relationship-with-disease-parameters
#15
JOURNAL ARTICLE
Rania M Gamal, Hanan Sayed M Abozaid, Mohmed Zidan, Mohamed Aboel-Kassem F Abdelmegid, Mohmed Raouf Abdel-Razek, Sahar Abdel-Rahman Alsayed, Amr F Mourad, Nashwa Mostafa A Azoz, Lobna Abdel-Wahid Mohram, Daniel E Furst
BACKGROUND/OBJECTIVES: Systemic sclerosis (SSc) is an autoimmune disease associated with immune abnormalities and widespread vascular lesions, including increased intimal and medial thickness. These changes may be reflected in early atherosclerosis and cardiovascular risks. We aimed in this study to examine the carotid artery intima-media thickness and MRI brain findings in SSc patients and compared them to a group of normal controls. A relationship between these parameters and clinical measures in SSc was also sought...
April 15, 2019: Arthritis Research & Therapy
https://read.qxmd.com/read/30188798/effects-of-testosterone-and-progressive-resistance-exercise-on-vascular-function-in-older-men
#16
JOURNAL ARTICLE
Kerry L Hildreth, Robert S Schwartz, Joseph Vande Griend, Wendy M Kohrt, Patrick J Blatchford, Kerrie L Moreau
The cardiovascular effects of testosterone (T) are controversial. Low T has been associated with accelerated vascular aging, characterized by large elastic artery stiffening (decreased compliance), intimal-medial thickening (IMT), and endothelial dysfunction. Endurance exercise improves vascular function, but resistance training may increase arterial stiffness. We sought to determine whether T supplementation improved markers of vascular aging in men with low-normal T, and whether T supplementation prevented arterial stiffness with resistance exercise...
September 6, 2018: Journal of Applied Physiology
https://read.qxmd.com/read/30105752/speckle-tracking-carotid-artery-circumferential-strain-is-a-marker-of-arterial-sclerosis-but-not-coronary-atherosis
#17
JOURNAL ARTICLE
Daniel M Patton, Terry Li, Marie-France Hétu, Andrew G Day, Erika Preece, Murray F Matangi, Amer M Johri
PURPOSE: Circumferential speckle tracking carotid artery strain is a novel method of quantifying vessel wall stiffness. We hypothesized that carotid wall stiffness would be associated with carotid intimal medial thickening (a medial process associated with risk factors), but not coronary artery disease (an intimal process). METHODS: Bilateral carotid artery ultrasound was conducted on outpatients who had previously undergone elective coronary angiography. Mean carotid artery far wall circumferential strain (FWCS) was assessed for correlations with coronary angiographic stenosis, cardiac risk factors, carotid intima-media thickness (CIMT), and carotid plaque...
August 13, 2018: Journal of Clinical Ultrasound: JCU
https://read.qxmd.com/read/29130662/-the-role-of-bone-morphogenic-protein-4-in-the-progression-of-vein-graft-hyperplastic-remodeling-under-hyperglycemic-condition
#18
JOURNAL ARTICLE
Deng-Feng Fang, Hong-Wei Zhang, Jun Gu, Kang-Jun Fan, Huai-Min Liang, Jia-Yu Shen, Er-Yong Zhang, Jia Hu
OBJECTIVE: This study was designed to assess the vessel wall characteristics and the expression levels of bone morphogenic protein4(BMP4) and proliferating cell antigen Ki67 in vein grafts harvested from diabetic rats,and to investigate the role of BMP4 in progression of vein graft hyperplastic remodeling under hyperglycemic condition. METHODS: 48 male SpragueDawky rats [body mass (194±16) g] aged 8 weeks were randomly divided into diabetes mellitus (DM) group ( n=24) and nondiabetes mellitus (NDM) group ( n=24)...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://read.qxmd.com/read/29040156/accelerated-atheromatosis-and-arteriosclerosis-in-primary-systemic-vasculitides-current-evidence-and-future-perspectives
#19
REVIEW
Ourania D Argyropoulou, Athanase D Protogerou, Petros P Sfikakis
PURPOSE OF REVIEW: Primary systemic vasculitides (PSV) encompass a subset of autoimmune diseases, characterized by inflammation of blood vessels. Atheromatosis and arteriosclerosis may be accelerated in several PSV and account for the increased rate of cardiovascular morbidity that some exhibit. We aimed to summarize recent studies reporting on the acceleration of atheromatosis and/or arteriosclerosis in each type of PSV, using state-of-the-art noninvasive vascular biomarkers with clinical value as end points...
January 2018: Current Opinion in Rheumatology
https://read.qxmd.com/read/28962112/epigallocatechin-3-gallate-attenuates-neointimal-hyperplasia-in-a-rat-model-of-carotid-artery-injury-by-inhibition-of-high-mobility-group-box-1-expression
#20
JOURNAL ARTICLE
Bin Yang, Peng Gao, Xuejun Wu, Jixiang Yu, Yu Li, Ranran Meng, Yubin Li, Jingqiang Yan, Xing Jin
Epigallocatechin-3-gallate (EGCG) is a kind of polyphenol compound, called catechin, and is extracted from green tea. EGCG has a wide range of biological activities. The present study aimed to evaluate the effect of EGCG on neointimal hyperplasia in a rat model of carotid artery balloon injury and to explore the molecular mechanisms involved. Various experiments were performed to assess the effects of EGCG on thickening of neointima, expression levels of high mobility group box 1 protein (HMGB1) and receptor of advanced glycation end products (RAGE), the inflammatory response, oxidative stress and activation of nuclear factor (NF)-κB...
September 2017: Experimental and Therapeutic Medicine
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