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https://www.readbyqxmd.com/read/29923491/three-trocar-laparoscopic-cholecystectomy-under-spinal-anesthesia-in-a-patient-with-asthma
#1
F Tatulli, A Delcuratolo, A Caraglia, A Notarnicola, F P N Carbone, A Caputi
INTRODUCTION: Laparoscopy is perceived as the state-of-the-art technique for a wide variety of operations but is contraindicated by comorbidities such as respiratory diseases. We present the case of a patient affected by asthma who underwent a successful three-trocar low-pressure pneumoperitoneum under spinal anesthesia. CASE REPORT: A 58 year-old male with symptomatic gallstones had partly-controlled asthma and respiratory allergies. Potential bronchospasm was avoided by a less invasive laparoscopic technique...
May 2018: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29889708/a-prospective-observational-study-of-anesthesia-related-adverse-events-and-postoperative-complications-occurring-during-a-surgical-mission-in-madagascar
#2
Michelle C White, Brian J Barki, Stephen A Lerma, Sarah Kate Couch, Dennis Alcorn, Richard G Gillerman
BACKGROUND: Two-thirds of the world's population lack access to safe anesthesia and surgical care. Nongovernmental organizations (NGOs) play an important role in bridging the gap, but surgical outcomes vary. After complex surgeries, up to 20-fold higher postoperative complication rates are reported and the reasons for poor outcomes are undefined. Little is known concerning the incidence of anesthesia complications. Mercy Ships uses fully trained staff, and infrastructure and equipment resources similar to that of high-income countries, allowing the influence of these factors to be disentangled from patient factors when evaluating anesthesia and surgical outcomes after NGO sponsored surgery...
June 8, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29883727/safer-anti-inflammatory-therapy-through-dual-cox-2-5-lox-inhibitors-a-structure-based-approach
#3
REVIEW
P Jaismy Jacob, S L Manju, K R Ethiraj, Geetha Elias
Inflammatory mediators of the arachidonic acid cascade from cyclooxygenase (COX) and lipoxygenase (LOX) pathways are primarily responsible for many diseases in human beings. Chronic inflammation is associated with the pathogenesis and progression of cancer, arthritis, autoimmune, cardiovascular and neurological diseases. Traditional non-steroidal anti-inflammatory agents (tNSAIDs) inhibit cyclooxygenase pathway non-selectively and produce gastric mucosal damage due to COX-1 inhibition and allergic reactions and bronchospasm resulting from increased leukotriene levels...
June 5, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29865929/noninvasive-ventilation-and-respiratory-physical-therapy-reduce-exercise-induced-bronchospasm-and-pulmonary-inflammation-in-children-with-asthma-randomized-clinical-trial
#4
Maisi Muniz Cabral David, Evelim Leal de Freitas Dantas Gomes, Maryjose Carvalho Mello, Dirceu Costa
BACKGROUND: Asthma is characterized by hyperresponsiveness of the airways, and exercise-induced bronchospasm (EIB) is a symptom that limits a large proportion of asthmatic patients, especially children. Continuous positive airway pressure (CPAP) leads to a reduction in the reactivity of the airways. The aim of this study was to evaluate the effect of outpatient treatment with CPAP and bilevel pressure combined with respiratory physical therapy for children and adolescents with asthma following bronchial hyperresponsiveness caused by an exercise bronchoprovocation test...
January 2018: Therapeutic Advances in Respiratory Disease
https://www.readbyqxmd.com/read/29851818/difficulty-in-tracheal-extubation-followed-by-tracheal-collapse-after-balloon-dilatation-for-tracheal-stenosis-therapy-a-case-report
#5
Nana Li, Linjia Zhu, Jie Sun, Yinbing Pan, Mei Gao
RATIONALE: Tracheobronchomalacia (TBM) refers to the weakening trachea or the trachea loss of structural integrity of airway cartilaginous structures. It causes tracheal stenosis, resulting in significantly high rates of mortality. Bronchoplasty by high-pressure balloon dilation under general anesthesia is a simple but effective and safe method to treat tracheobronchial stenosis. However, recurrent postoperative dyspnea after extubation due to tracheal collapse is still a challenge for anesthetists...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29844139/safety-of-oral-propranolol-for-infantile-hemangioma
#6
Catherine Droitcourt, Sandrine Kerbrat, Caroline Rault, Marie-Anne Botrel, André Happe, Ronan Garlantezec, Bernard Guillot, Jean-Marc Schleich, Emmanuel Oger, Alain Dupuy
OBJECTIVES: The safety of oral propranolol for infantile hemangioma has not yet been studied at population level since the pediatric use marketing authorization was obtained in Europe. METHODS: A survey of a nationwide, claim-based observational cohort of children <3 years old, with at least 1 delivery of oral propranolol between July 2014 and June 2016, was performed by using the database of the French National Health Insurance system. Standardized morbidity ratios (SMRs) were calculated by using, from the same database, a representative random sample of nonexposed subjects...
May 29, 2018: Pediatrics
https://www.readbyqxmd.com/read/29812983/a-checklist-manifesto-effectiveness-of-checklist-use-in-hands-on-simulation-examining-competency-in-contrast-reaction-management-in-a-randomized-controlled-study
#7
Sana Parsian, Ryan B O'Malley, Daniel S Hippe, William H Bush, Puneet Bhargava, Linda E Chen, Carolyn L Wang
OBJECTIVE: The purpose of this article is to assess the performance of a contrast reaction management checklist for optimal management of a contrast reaction scenario created using a high-fidelity hands-on simulation. MATERIALS AND METHODS: A safety checklist was designed that presented the five adverse events that most commonly occur after administration of IV contrast medium as well as their step-by-step management. Forty-three radiology residents were randomized into two groups, a checklist group (n = 22) and a control group (n = 21), as stratified by postgraduate year...
May 29, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29802008/-peri-operative-management-of-smoking
#8
REVIEW
A-M Ruppert, F Amrioui, V Fallet, J Cadranel
Smoking is a public health issue, especially during the perioperative period. Tobacco increases the risk of hospital mortality by 20% and major postoperative complications by 40%. Active smoking is associated with respiratory complications particularly bronchospasm and pneumonia, but also all surgical complications as scar infections, local thrombosis, suture release and delayed bone healing. The perioperative period is an opportunity to stop smoking. Smoking cessation should always be recommended, regardless of the surgery and the date of intervention...
May 22, 2018: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29777744/omalizumab-can-inhibit-respiratory-reaction-during-aspirin-desensitization
#9
David M Lang, Mark A Aronica, Elizabeth S Maierson, Xiao-Feng Wang, Dorothy C Vasas, Stanley L Hazen
BACKGROUND: Aspirin desensitization has been associated with benefit in management of aspirin exacerbated respiratory disease (AERD). An intervention that would encourage aspirin desensitization to be performed more frequently has substantial potential for improving outcomes and quality of life in patients with AERD. OBJECTIVE: We investigated whether omalizumab administration would be associated with attenuation of aspirin-provoked bronchospasm in patients with AERD undergoing aspirin desensitization...
May 16, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29750690/rates-of-perioperative-respiratory-adverse-events-among-caucasian-and-african-american-children-undergoing-general-anesthesia
#10
Sarah Tariq, Madiha Syed, Timothy Martin, Xu Zhang, Michael Schmitz
BACKGROUND: Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial groups. Identification of high-risk groups can guide decision making in the perioperative period, and aggressive optimization of specific care can enhance safety and improve outcomes...
May 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29747661/modelling-the-asthma-phenotype-impact-of-cigarette-smoke-exposure
#11
Maria G Belvisi, Katie Baker, Nicole Malloy, Kristof Raemdonck, Bilel Dekkak, Michael Pieper, Anthony T Nials, Mark A Birrell
BACKGROUND: Asthmatics that are exposed to inhaled pollutants such as cigarette smoke (CS) have increased symptom severity. Approximately 25% of adult asthmatics are thought to be active smokers and many sufferers, especially in the third world, are exposed to high levels of inhaled pollutants. The mechanism by which CS or other airborne pollutants alter the disease phenotype and the effectiveness of treatment in asthma is not known. The aim of this study was to determine the impact of CS exposure on the phenotype and treatment sensitivity of rodent models of allergic asthma...
May 10, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29724380/exercise-induced-bronchospasm-in-children-and-adolescents-with-allergic-rhinitis-by-treadmill-and-hyperventilation-challenges
#12
Edil de Albuquerque Rodrigues Filho, José Ângelo Rizzo, Adriana Velozo Gonçalves, Marco Aurélio de Valois Correia Junior, Emanuel Sávio Cavalcanti Sarinho, Décio Medeiros
BACKGROUND: Respiratory complaints after exercise are common in patients with rhinitis. Exercise-induced bronchospasm (EIB) may be one of the causes. OBJECTIVES: To evaluate EIB prevalence in a group of children and adolescents with allergic rhinitis, to compare the treadmill running (TR) and eucapnic voluntary hyperventilation (EVH) challenge methods as diagnostic tools and to assess the association between respiratory complaints on exercise and EIB. METHODS: Patients aged between 10 and 20 years were studied at the Pulmonology Department of the Hospital das Clínicas -UFPE- Recife, Brazil...
May 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29723946/-plantago-psyllium-secondary-anaphylaxis-case-report
#13
Rodrigo Collado-Chagoya, Javier Hernández-Romero, Gumaro Alejandro Eliosa-Alvarado, Ana Carmen García-González, Rosa Isela Campos-Gutiérrez, Andrea Velasco-Medina, Guillermo Velázquez-Sámano
BACKGROUND: Psyllium is a derivative of Plantago ovata ground seed and husk that is used as bulk-forming laxatives owing to its hydrocolloid properties. CASE REPORT: 43-year-old female nurse with previous diagnosis of drug allergy and allergic rhinitis who, after the preparation and administration of a laxative, developed rhinoconjunctivitis symptoms, urticarial syndrome, angioedema and bronchospasm, which led to conclude that she had an anaphylactic reaction. She was treated with adrenaline, corticosteroids and antihistamines...
January 2018: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29722428/futility-of-current-urine-salbutamol-doping-control
#14
Jules A A C Heuberger, Sven C van Dijkman, Adam F Cohen
AIMS: Salbutamol is used in the management of obstructive bronchospasm, including that of some elite athletes. It is claimed that high salbutamol (oral) doses may also have an anabolic effect. Therefore, inhalation of salbutamol is restricted by the World Anti-Doping Agency (WADA) to a maximal daily dose. Urine is tested for violations, but recent cases have resulted in a debate regarding the validity of this approach. It was our aim to determine whether current approaches are sufficiently able to differentiate approved usage from violations...
May 3, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29722341/halogen-inhalation-induced-lung-injury-and-acute-respiratory-distress-syndrome
#15
REVIEW
Ting Zhou, Wei-Feng Song, You Shang, Shang-Long Yao, Sadis Matalon
Objective: Exposure to halogens, such as chlorine or bromine, results in environmental and occupational hazard to the lung and other organs. Chlorine is highly toxic by inhalation, leading to dyspnea, hypoxemia, airway obstruction, pneumonitis, pulmonary edema, and acute respiratory distress syndrome (ARDS). Although bromine is less reactive and oxidative than chlorine, inhalation also results in bronchospasm, airway hyperresponsiveness, ARDS, and even death. Both halogens have been shown to damage the systemic circulation and result in cardiac injury as well...
May 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29696118/anesthetic-considerations-for-angelman-syndrome-case-series-and-review-of-the-literature
#16
Mary Ellen Warner, David P Martin, Mark A Warner, Ralitza H Gavrilova, Juraj Sprung, Toby N Weingarten
Background: Angelman syndrome is a rare neurodevelopmental disorder characterized by intellectual disability, severe speech impairment, ataxia, seizures, happy demeanor, distinctive craniofacial features, high vagal tone, and gamma-amino butyric acid receptor abnormalities. The aim of this report is to review our experience of patients with Angelman syndrome undergoing anesthetic management. Methods: We retrospectively reviewed perioperative course of patients with Angelman syndrome who underwent procedures under anesthesia from 2000 to 2016...
October 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29688079/acute-adverse-events-associated-with-the-administration-of-crotalidae-polyvalent-immune-fab-antivenom-within-the-north-american-snakebite-registry
#17
Kurt Kleinschmidt, Anne-Michelle Ruha, Sharan Campleman, Jeffrey Brent, Paul Wax
BACKGROUND: Crotalidae Polyvalent Immune Fab (Fab Antivenom) is the primary Viperid antivenom used in the United States since 2000. Adverse event data associated with its use are limited. The purpose of this study is to describe the prevalence of acute adverse events associated with the use of Fab antivenom. METHODS: The American College of Medical Toxicology's Toxicology Investigators Consortium maintains a prospective case registry of poisoned and envenomated patients managed by medical toxicologists at the bedside...
April 24, 2018: Clinical Toxicology
https://www.readbyqxmd.com/read/29678900/prevention-of-exacerbations-in-patients-with-stable-non-cystic-fibrosis-bronchiectasis-a-systematic-review-and-meta-analysis-of-pharmacological-and-non-pharmacological-therapies
#18
Abd Moain Abu Dabrh, Adam T Hill, Claudia C Dobler, Noor Asi, Wigdan H Farah, Qusay Haydour, Zhen Wang, Khalid Benkhadra, Larry J Prokop, Mohammad Hassan Murad
BACKGROUND: Several pharmacological and non-pharmacological therapies are used to treat stable bronchiectasis of non-cystic fibrosis (CF) aetiology. OBJECTIVE: We conducted a systematic review and meta-analysis to assess the evidence of the effectiveness of pharmacological and non-pharmacological treatment options in patients with stable non-CF bronchiectasis with a focus on reducing exacerbations. STUDY SELECTION: Multiple databases were searched through September 2017...
April 20, 2018: BMJ evidence-based medicine
https://www.readbyqxmd.com/read/29669772/a-case-of-h3n2-complicated-by-acute-kidney-injury-secondary-to-rhabdomyolysis
#19
Sriram Gonakoti, Janak Bahirwani, Raja Naga Mahesh Maddala, Sudha Vidyasagar
H3N2 was first detected in July 2011 in the USA. It is responsible for sporadic cases of influenza and localised outbreaks and has not yet taken over on an epidemic or pandemic scale. An 84-year-old man presented with a dry cough, fever and myalgia for 3 days. On examination, he had a pulse of 98 bpm and blood pressure of 124/88 mm Hg. The patient was tachypnoeic, SpO2 was 90%. Auscultation revealed bilateral diffuse wheeze and crackles. He had generalised muscle tenderness on examination. On admission, creatinine was 1...
April 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29669068/adverse-reactions-after-intravenous-iron-infusion-among-inflammatory-bowel-disease-patients-in-the-united-states-2010-2014
#20
Eboselume Akhuemonkhan, Alyssa Parian, Kathryn A Carson, Susan Hutfless
Background: Anemia is a frequent complication of Crohn's disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel disease (IBD). Intravenous (IV) iron is recommended as the initial therapy for patients with clinically active IBD, severe anemia, and intolerance to oral iron. IV iron is associated with serious adverse effects including a black box warning for anaphylaxis with iron dextran and ferumoxytol. We aimed to examine the occurrence of adverse reactions including anaphylaxis after IV iron infusions in a large database of US IBD patients...
April 13, 2018: Inflammatory Bowel Diseases
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