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https://www.readbyqxmd.com/read/28651197/ascorbic-acid-protects-coccomyxa-subellipsoidea-against-metal-toxicity-through-modulation-of-ros-no-balance-and-metal-uptake
#1
Jozef Kováčik, Gabriela Rotková, Marek Bujdoš, Petr Babula, Viera Peterková, Peter Matúš
Impact of exogenous ascorbic acid (AsA, 100μM) on acute metal toxicity (Pb and Hg, 24h of exposure to 100μM) in unicellular green alga Coccomyxa subellipsoidea was studied. Hg (often extensively) depleted amount of pigments, potassium, soluble proteins, endogenous AsA, non-protein thiols and nitric oxide signal but elevated ROS signal and activities of catalase and superoxide dismutase. Responses to Pb application (if any) were less visible with ROS signal being slightly elevated and amount of non-protein thiols being slightly reduced...
June 16, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28649639/initial-assessment-of-the-nutritional-quality-of-the-space-food-system-over-three-years-of-ambient-storage
#2
Maya Cooper, Michele Perchonok, Grace L Douglas
Processed and prepackaged space food is the main source of nutrition for crew aboard the International Space Station, and likely will continue to be the main source of nutrition for future exploration missions. However, very little information is available on the nutritional stability of space foods. To better understand their nutritional stability, 24 micronutrients were measured in 109 space foods stored over 3 years at room temperature. Our analysis indicated that potassium, calcium, vitamin D, and vitamin K concentrations in the food may not be adequate to meet the recommended daily intake requirements even before storage...
2017: NPJ Microgravity
https://www.readbyqxmd.com/read/28649232/ion-channels-of-pituitary-gonadotrophs-and-their-roles-in-signaling-and-secretion
#3
REVIEW
Stanko S Stojilkovic, Ivana Bjelobaba, Hana Zemkova
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration. These cells fire action potentials (APs) spontaneously, coupled with voltage-gated calcium influx of insufficient amplitude to trigger gonadotropin release. The spontaneous excitability of gonadotrophs reflects the expression of voltage-gated sodium, calcium, potassium, non-selective cation-conducting, and chloride channels at their plasma membrane (PM)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28649075/hypouricemic-and-nephroprotective-effects-of-total-flavonoids-from-the-residue-of-supercritical-co2-extraction-of-humulus-lupulus-in-potassium-oxonate-induced-mice
#4
Zhen Jing Li, Zhuan Li, Xiao Ying Dong, Lai Feng Lu, Chang Lu Wang
Total flavonoids of Humulus lupulus (TFHL) were prepared using ethanol extraction, liquid-liquid partition and purification with polyamide resin. Different dose of TFHL were orally administered to normal and hyperuricemic mice for 7 days. The xanthine oxidase (XOD) inhibitory activity and hypouricemic effects of TFHL on potassium oxonate-induced hyperuricemic mice were examined. The TFHL showed very potent XOD inhibitory activity with IC50=66.8 μg/mL. At a single oral dose of 100mg/kg TFHL, the serum uric acid levels of hyperuricemic mice significantly decreased (P<0...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649029/determination-of-chemical-oxygen-demand-cod-using-an-alternative-wet-chemical-method-free-of-mercury-and-dichromate
#5
Marit Kolb, Müfit Bahadir, Burkhard Teichgräber
Worldwide, the standard methods for the determination of the important wastewater parameter chemical oxygen demand (COD) are still based on the use of the hazardous chemicals, mercury sulfate and chromium(VI). However, due to their properties they are meanwhile classified as "priority pollutants" and shall be phased out or banned in the frame of REACH (current European Chemical Law: Registration, Evaluation, Authorization and restriction of Chemicals) by the European Union. Hence, a new wet-chemical method free of mercury and chromium(VI) was developed...
June 13, 2017: Water Research
https://www.readbyqxmd.com/read/28649022/a-portable-rgb-sensing-gadget-for-sensitive-detection-of-hg-2-using-cysteamine-capped-qds-as-fluorescence-probe
#6
Bin Chen, Jun Ma, Tong Yang, Lin Chen, Peng Fei Gao, Cheng Zhi Huang
A facile one-pot method was proposed to synthesis cysteamine capped CdTe QDs with a high quantum yield 30%. In the synthesis process, nitrogen protection, ultrasonic treatment, and light irradiation were unnecessary. Additionally, potassium tellurite was used instead of Te powder as Te source, avoiding of the time-consuming Te powder dissolution process. The prepared QDs were found to be Hg(2+) sensitive. The detection linear range for Hg(2+) was from 5 to 300nM, and the detection limit was calculated to be 1nM...
June 8, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28648999/in%C3%A2-vitro-protein-synthesis-of-sugar-beet-beta-vulgaris-and-maize-zea-mays-is-differentially-inhibited-when-potassium-is-substituted-by-sodium
#7
Franziska Faust, Sven Schubert
The substitution of potassium ions (K(+)) by sodium ions (Na(+)) in the nutrition of plants is restricted. It was shown earlier that net protein synthesis is the process which is most sensitive to the substitution of K(+) by Na(+) in young sugar beet. We hypothesized that the activity of ribosomes is inhibited by the substitution. This hypothesis was tested in an in vitro approach. Cytosolic polysomes were isolated from growing leaves of sugar beet and maize by means of differential centrifugation. In vitro systems of both plant species were tested for functionality and comparability...
June 15, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28648645/functional-interaction-of-the-two-pore-domain-potassium-channel-task-1-and-caveolin-3
#8
Chen Kang, Victor Hernandez, Keli Hu
The two-pore domain potassium channel TASK-1 is strongly expressed in the heart and has been shown to modulate the resting membrane potential and action potential. However, little is known about the regulation of TASK-1 channels. The present study was designed to determine whether TASK-1 is modulated by caveolin-3, a primary structural protein of cardiac caveolae. Functional studies with the whole-cell voltage clamp technique showed that the expression of caveolin-3 decreased recombinant TASK-1 currents significantly in HEK293T cells, and this effect was prevented by co-expressing the dominant negative mutant caveolin-3 P104L...
June 22, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28647557/kcc3-loss-of-function-contributes-to-andermann-syndrome-by-inducing-activity-dependent-neuromuscular-junction-defects
#9
Melissa Bowerman, Céline Salsac, Véronique Bernard, Claire Soulard, Annie Dionne, Emmanuelle Coque, Salim Benlefki, Pascale Hince, Patrick A Dion, Gillian Butler-Browne, William Camu, Jean-Pierre Bouchard, Eric Delpire, Guy A Rouleau, Cédric Raoul, Frédérique Scamps
Loss-of-function mutations in the potassium-chloride cotransporter KCC3 lead to Andermann syndrome, a severe sensorimotor neuropathy characterized by areflexia, amyotrophy and locomotor abnormalities. The molecular events responsible for axonal loss remain poorly understood. Here, we establish that global or neuron-specific KCC3 loss-of-function in mice leads to early neuromuscular junction (NMJ) abnormalities and muscular atrophy that are consistent with the pre-synaptic neurotransmission defects observed in patients...
June 21, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28647292/risk-factors-of-refeeding-syndrome-in-malnourished-older-hospitalized-patients
#10
Maryam Pourhassan, Ingeborg Cuvelier, Ilse Gehrke, Christian Marburger, Mirja Katrin Modreker, Dorothee Volkert, Hans-Peter Willschrei, Rainer Wirth
BACKGROUND & AIMS: Despite the high prevalence of malnutrition among older hospitalized persons, it is unknown how many of these malnourished patients are at risk of developing the refeeding syndrome (RFS). In this study, we sought to compare the prevalence and severity of malnutrition among older hospitalized patients with prevalence of known risk factors of RFS. METHODS: This cross-sectional multicenter-study investigated older participants who were consecutively admitted to the geriatric acute care ward...
June 10, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28646982/serum-potassium-and-the-long-interdialytic-interval-minding%C3%A2-the%C3%A2-gap
#11
EDITORIAL
Connie M Rhee
No abstract text is available yet for this article.
July 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28646979/inhibition-of-rapid-delayed-rectifier-potassium-current-ikr-by-ischemia-reperfusion-and-its-recovery-by-vitamin-e-in-ventricular-myocytes
#12
Yaoxu Chen, Chunxia Yin, Yingying Yang, Zhuo Fan, Jinling Shang, Wen Tan
Ischemia/reperfusion (I/R) induces prolongation of QT interval and action potential duration (APD), which is a major cardiac electrical disorder in patients with arrhythmias. However, the mechanism of QT interval prolongation induced by I/R remains unclear. In the present study, we hypothesized that the rapid component of delayed rectifier potassium (IKr) channel plays an important role in I/R-induced QT interval prolongation. We observed a marked attenuation of IKr and a significant prolongation of action potential duration (APD) in a simulated I/R system with sodium dithionite (Na2S2O4) in ventricular myocytes of guinea pigs...
July 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28646831/assessment-of-differences-in-nutrients-consumption-in-women-diagnosed-with-osteoporosis-as-compared-to-a-healthy-control-group
#13
Agata Wawrzyniak, Patrycja Klimczyk, Agnieszka Woźniak, Anna Anyżewska, Magdalena Leonkiewicz
Background: Osteoporosis is a condition that has been much more frequent for women, which is related to menopause and to their lower bone mineral density (BMD). Inappropriate diet is among the development factors of the disease. Objective: To assess differences in consumption of particular nutrients among women with and without osteoporosis diagnosed. Material and Methods: The study was conducted in 2013 in a group of 100 women aged 51-70, using a questionnaire, including a 24-hour recall related to a participant’s nutrients consumptions...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28646567/severe-menses-associated-hypertension-successfully-treated-with-gonadotropin-releasing-hormone-agonist
#14
Luke J Laffin, Munnam S Jafar, George L Bakris
A case of a 32-year-old nulliparous white woman referred for a 5-year history of severe hypertension, hypokalemia, and resultant systolic dysfunction is presented. She additionally had a left ventricular ejection fraction of 30% including left ventricular dilation and normal left ventricular mass index, as measured by cardiac magnetic resonance imaging when she initially presented to us. Her history revealed that her severe hypertension episodes were monthly and would occur around the catamenial (menses-associated) time...
June 23, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28646309/influence-of-polymethyl-acrylate-additive-on-the-formation-of-particulate-matter-and-nox-emission-of-a-biodiesel-diesel-fueled-engine
#15
Islam Mohammad Monirul, Haji Hassan Masjuki, Mohammad Abdul Kalam, Nurin Wahidah Mohd Zulkifli, Islam Shancita
The aim of this study is to investigate the effect of the polymethyl acrylate (PMA) additive on the formation of particulate matter (PM) and nitrogen oxide (NOX) emission from a diesel coconut and/or Calophyllum inophyllum biodiesel-fueled engine. The physicochemical properties of 20% of coconut and/or C. inophyllum biodiesel-diesel blend (B20), 0.03 wt% of PMA with B20 (B20P), and diesel fuel were measured and compared to ASTM D6751, D7467, and EN 14214 standard. The test results showed that the addition of PMA additive with B20 significantly improves the cold-flow properties such as pour point (PP), cloud point (CP), and cold filter plugging point (CFPP)...
June 23, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28645860/gper-agonist-dilates-mesenteric-arteries-via-pi3k-akt-enos-and-potassium-channels-in-both-sexes
#16
Pollyana Peixoto, Rosária Dias Aires, Virgínia Soares Lemos, Nazaré Souza Bissoli, Roger Lyrio Dos Santos
AIM: The action of oestrogen has traditionally been attributed to the activation of nuclear receptors (ERα and ERβ). A third receptor, the G protein-coupled oestrogen receptor (GPER), has been described as mediator of the rapid action of oestrogen. Based on the possible protective role of oestrogen in the cardiovascular system, the present study was designed to determine whether selective GPER activation induces relaxation of mesenteric resistance arteries in both sexes and which signalling pathways are involved...
June 20, 2017: Life Sciences
https://www.readbyqxmd.com/read/28645648/promotion-of-iron-nutrition-and-growth-on-peanut-by-paenibacillus-illinoisensis-and-bacillus-sp-strains-in-calcareous-soil
#17
Di Liu, Qianqian Yang, Ke Ge, Xiuna Hu, Guozhen Qi, Binghai Du, Kai Liu, Yanqin Ding
This study aimed to explore the effects of two siderophore-producing bacterial strains on iron absorption and plant growth of peanut in calcareous soil. Two siderophore-producing bacterial strains, namely, YZ29 and DZ13, isolated from the rhizosphere soil of peanut, were identified as Paenibacillus illinoisensis and Bacillus sp., respectively. In potted experiments, YZ29 and DZ13 enhanced root activity, chlorophyll and active iron content in leaves, total nitrogen, phosphorus and potassium accumulation of plants and increased the quality of peanut kernels and plant biomass over control...
June 4, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28644481/redox-controlled-potassium-intercalation-into-two-polyaromatic-hydrocarbon-solids
#18
F Denis Romero, M J Pitcher, C I Hiley, G F S Whitehead, S Kar, A Y Ganin, D Antypov, C Collins, M S Dyer, G Klupp, R H Colman, K Prassides, M J Rosseinsky
Alkali metal intercalation into polyaromatic hydrocarbons (PAHs) has been studied intensely after reports of superconductivity in a number of potassium- and rubidium-intercalated materials. There are, however, no reported crystal structures to inform our understanding of the chemistry and physics because of the complex reactivity of PAHs with strong reducing agents at high temperature. Here we present the synthesis of crystalline K2Pentacene and K2Picene by a solid-solid insertion protocol that uses potassium hydride as a redox-controlled reducing agent to access the PAH dianions, and so enables the determination of their crystal structures...
July 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28644255/periodic-paralysis-and-encephalopathy-as-initial-manifestations-of-graves-disease-case-report-and-review-of-the-literature
#19
Theocharis Tsironis, Athanasios Tychalas, Dimitrios Kiourtidis, Jannis Kountouras, Georgia Xiromerisiou, Jobst Rudolf, Georgia Deretzi
BACKGROUND: Thyrotoxic periodic paralysis (TPP) is an uncommon complication of Graves' disease, characterized by the triad of acute hypokalemia without total body potassium deficit, episodic muscle paralysis, and thyrotoxicosis. Graves' encephalopathy is an extremely rare form of encephalopathy associated with autoimmune thyroid disease (EAATD), characterized by neuropsychiatric symptoms, increased antithyroid antibodies and cerebrospinal fluid protein concentration, nonspecific electroencephalogram abnormalities, and cortico-responsiveness...
July 2017: Neurologist
https://www.readbyqxmd.com/read/28643868/the-potassium-battery-a-mobile-energy-source-for-transport-processes-in-plant-vascular-tissues
#20
REVIEW
Ingo Dreyer, Judith Lucia Gomez-Porras, Janin Riedelsberger
Contents I. II. III. IV. V. VI. VII. VIII. References SUMMARY: Plant roots absorb potassium ions from the soil and transport them in the xylem via the transpiration stream to the shoots. There, in source tissues where sufficient chemical energy (ATP) is available, K(+) is loaded into the phloem and then transported with the phloem stream to other parts of the plant; in part, transport is also back to the roots. This, at first sight, futile cycling of K(+) has been uncovered to be part of a sophisticated mechanism that (1) enables the shoot to communicate its nutrient demand to the root, (2) contributes to the K(+) nutrition of transport phloem tissues and (3) transports energy stored in the K(+) gradient between phloem cytosol and the apoplast...
June 23, 2017: New Phytologist
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