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Left atrial appendage closure

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https://www.readbyqxmd.com/read/29143099/-left-atrial-appendage-clusure-in-nonvalvular-atrial-fibrillation-clinical-evidence-2017
#1
REVIEW
Steffen Gloekler, Bajram Hajredini, Simon Rycerz, Sebastian Jäckle, Werner Jung
Nonvalvular atrial fibrillation (AF) is the most common arrhythmia with a prevalence of 1-2% and affects approximately 15-20% of all octogenarians. Patients are at increased risk of thromboembolic stroke, with an overall risk of 5% per year. Thrombi form almost exclusively in the left atrial appendage (LAA), a blind sac-like heterogeneous structure trabeculated by pectinate muscles. In the past five decades, life-long oral anticoagulation (OAC) with vitamin K antagonists (VKA) has been the state-of-the art treatment to prevent stroke and systemic embolism from thrombi in AF...
November 15, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29130638/thromboembolism-after-watchman-tm-in-a-clopidogrel-non-responder-a-case-for-concern
#2
Ganesh Venkataraman, Kevin P Bliden, Udaya S Tantry, Paul A Gurbel
Atrial fibrillation (AF) is associated with an increased risk of stroke and thromboembolism (TE). The WATCHMAN(TM) left atrial appendage (LAA) closure device is indicated to reduce the risk of TE from the LAA in patients with non-valvular AF. Here, we present a case of a patient with device-related thrombus who suffered a TE event two months after WATCHMAN(TM) LAA closure and two weeks after switching from aspirin plus warfarin to aspirin plus clopidogrel therapy. Laboratory investigation identified the patient to be hypercoagulable and to be a non-responder to clopidogrel therapy...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29122135/transseptal-puncture-through-amplatzer-atrial-septal-occluder-for-left-atrial-appendage-closure
#3
Steffen Gloekler, Samera Shakir, Bernhard Meier
No abstract text is available yet for this article.
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29122134/left-atrial-appendage-closure-continuous-progress-with-remaining-challenges
#4
EDITORIAL
Horst Sievert, Stefan Bertog
No abstract text is available yet for this article.
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29122133/percutaneous-left-atrial-appendage-closure-with-the-lambre-device-for-stroke%C3%A2-prevention-in-atrial-fibrillation-a-prospective-multicenter-clinical-study
#5
He Huang, Yu Liu, Yawei Xu, Zulu Wang, Yigang Li, Kejiang Cao, Shu Zhang, Yanzong Yang, Xinchun Yang, Dejia Huang, Bo Yu, Xi Su, Liqun Wu, Congxin Huang
OBJECTIVES: The authors sought to assess the clinical outcomes of left atrial appendage (LAA) closure with the LAmbre closure system in patients with nonvalvular atrial fibrillation (NVAF). BACKGROUND: Over 90% of thrombi are located in the LAA in NVAF patients. METHODS: A prospective, multicenter study was conducted in 153 NVAF patients with CHADS2 score ≥1. RESULTS: The LAA was successfully occluded in 152 patients...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29113720/spanish-cardiac-catheterization-and-coronary-intervention-registry-26th-official-report-of-the-spanish-society-of-cardiology-working-group-on-cardiac-catheterization-and-interventional-cardiology-1990-2016
#6
Ana María Serrador Frutos, Pilar Jiménez-Quevedo, Armando Pérez de Prado, Manuel Pan Álvarez-Ossorio
INTRODUCTION AND OBJECTIVES: The Working Group on Cardiac Catheterization and Interventional Cardiology presents its annual report on the activity data for 2016. METHODS: All Spanish hospitals with catheterization laboratories were invited to voluntarily contribute their activity data. The information was collected online and was analyzed mainly by an independent company. RESULTS: In 2016, 106 centers participated in the national registry; 80 of these centers are public...
November 4, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29106834/-left-atrial-appendage-closure-and-embolic-events
#7
M Akodad, P Garot
Atrial fibrillation (AF) is frequent and responsible for embolic events. Currently, the gold standard to prevent such embolic events is anticoagulant therapy with vitamin K antagonist (VKA) or direct oral anticoagulant in nonvalvular AF. Recently, left atrial appendage closure was proposed as an alternative to anticoagulant inpatient with high embolic risk and contraindication to anticoagulant therapy. Data from randomized trials were consistent with a non-inferiority of left atrial appendage closure in comparison to VKA in terms of stroke and cardiovascular death...
October 26, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29106523/combining-watchman-left-atrial-appendage-closure-and-catheter-ablation-for-atrial-fibrillation-multicentre-registry-results-of-feasibility-and-safety-during-implant-and-30-days-follow-up
#8
Karen P Phillips, Evgeny Pokushalov, Aleksandr Romanov, Sergey Artemenko, Richard J Folkeringa, Tamas Szili-Torok, Gaetano Senatore, Kenneth M Stein, Omar Razali, Nicole Gordon, Lucas V A Boersma
Aims: Long-term results from catheter ablation therapy for atrial fibrillation (AF) remain uncertain and clinical practice guidelines recommend continuation of long-term oral anticoagulation in patients with a high stroke risk. Left atrial appendage closure (LAAC) with Watchman has emerged as an alternative to long-term anticoagulation for patients accepting of the procedural risks. We report on the initial results of combining catheter ablation procedures for AF and LAAC in a multicentre registry...
July 3, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29104013/long-term-results-with-left-atrial-appendage-closure-watching-the-watchman
#9
EDITORIAL
Jacqueline Saw
No abstract text is available yet for this article.
October 25, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29103847/5-year-outcomes-after-left%C3%A2-atrial%C3%A2-appendage-closure-from-the-prevail-and-protect-af-trials
#10
Vivek Y Reddy, Shephal K Doshi, Saibal Kar, Douglas N Gibson, Matthew J Price, Kenneth Huber, Rodney P Horton, Maurice Buchbinder, Petr Neuzil, Nicole T Gordon, David R Holmes
BACKGROUND: The PROTECT AF (WATCHMAN Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) trial demonstrated that left atrial appendage closure (LAAC) with the Watchman device (Boston Scientific, St. Paul, Minnesota) was equivalent to warfarin for preventing stroke in atrial fibrillation, but had a high rate of complications. In a second randomized trial, PREVAIL (Evaluation of the WATCHMAN LAA Closure Device in Patients With Atrial Fibrillation Versus Long Term Warfarin Therapy), the complication rate was low...
November 4, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29101545/-recent-and-upcoming-randomized-trials-for-left-atrial-appendage-occlusion-need-for-a-definite-assessment-of-the-situation
#11
REVIEW
Carsten Skurk, Johannes Jakob Hartung, Ulf Landmesser
Atrial fibrillation (AF) is the most common arrhythmia affecting more than 1.6 million patients in Germany. Based on demographic developments, an the number is expected to increase. Embolic strokes in AF patients are particularly severe, and individualized new oral anticoagulant (NOAC) therapy reduces the incidence of stroke in these patients by approximately 70%. Besides vitamin K antagonists, the NOACs rivaroxaban, dabigatran, apixaban, and edoxaban have been introduced into clinical practice; however, major bleeding still occurs at a rate of 2-3% per year...
November 3, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29101544/anatomy-of-the-atria-a%C3%A2-road-map-to-the-left-atrial-appendage
#12
REVIEW
Umberto Barbero, Siew Yen Ho
The left atrial appendage (LAA) has received increasing attention in recent years because of thrombi formation in patients with atrial fibrillation, which increases the risk of stroke. In patients who have contraindications for long-term oral anticoagulation therapy, percutaneous procedures are used to occlude the LAA and there are now several devices available for implantation, both endocardially and epicardially. Despite the high-resolution imaging techniques on hand today, limitations remain in providing information about wall thickness and neighboring structures; therefore, in-depth knowledge of the normal atrial anatomy is mandatory when considering such interventions...
November 3, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29089965/evaluation-of-left-atrial-remodelling-following-percutaneous-left-atrial-appendage-closure
#13
Zakaria Jalal, Xavier Iriart, Marie-Lou Dinet, Olivier Corneloup, Xavier Pillois, Hubert Cochet, Jean-Benoît Thambo
No abstract text is available yet for this article.
August 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29069203/first-results-of-the-brazilian-registry-of-percutaneous-left-atrial-appendage-closure
#14
Ênio Eduardo Guérios, Francisco Chamié, Márcio Montenegro, Eduardo Benchimol Saad, Fabio Sandoli de Brito, Paulo Avancini Caramori, Luiz Carlos Simões, Flávio Roberto Azevedo de Oliveira, Luiz Carlos Giuliano, Cláudio Munhoz da Fontoura Tavares
BACKGROUND: Left atrial appendage closure (LAAC) is an effective alternative to oral anticoagulation (OA) for the prevention of stroke in patients with non-valvular atrial fibrillation (NVAF). OBJECTIVE: To present the immediate results and late outcomes of patients submitted to LAAC and included in the Brazilian Registry of Percutaneous Left Atrial Appendage Closure. METHODS: 91 patients with NVAF, high stroke risk (CHA2DS2VASc score = 4...
October 19, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29047250/simultaneous-closure-of-a-left-atrial-appendage-through-an-atrial-septal-defect-and-the-atrial-septal-defect
#15
Shinjeong Song, Oh Hyun Lee, Jung Sun Kim, In Jeong Cho, Chi Young Shim, Geu Ru Hong, Hui Nam Pak, Yangsoo Jang
Left atrial appendage (LAA) occlusion can be employed as an alternative treatment to oral anticoagulation in patients with atrial fibrillation to prevent embolic events. Atrial septal defect (ASD) may be related with right heart dysfunction and allow paradoxical embolism to occur. However, occlusion of both LAA through atrial access with ostium secundum ASD and ASD in the same setting is unusual. Therefore, we report a case in which a LAA and an ASD was sequentially occluded.
November 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29039312/left-atrial-appendage-closure-size-does-matter
#16
Guy Achkouty, Adela Rohnean, Christophe Caussin, Nicolas Amabile
No abstract text is available yet for this article.
October 17, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29030234/left-atrial-appendage-closure-devices-a-reasonable-therapeutic-alternative
#17
Vivek Y Reddy
No abstract text is available yet for this article.
October 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29030233/percutaneous-left-atrial-appendage-closure-is-not-ready-for-routine-clinical-use
#18
John Mandrola, Andrew Foy, Gerald Naccarelli
No abstract text is available yet for this article.
October 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29019613/uncommon-cause-of-dyspnoea-after-percutaneous-closure-of-the-left-atrial-appendage
#19
Martin Orban, Stefan Brunner, Steffen Massberg, Axel Bauer
No abstract text is available yet for this article.
October 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28988462/exploring-the-dark-side-of-left-atrial-appendage-closure-devices
#20
EDITORIAL
Pasquale Santangeli, Andrew E Epstein
No abstract text is available yet for this article.
October 8, 2017: Journal of Cardiovascular Electrophysiology
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