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intravascular lymphoma

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https://www.readbyqxmd.com/read/29780139/methotrexate-associated-intravascular-large-b-cell-lymphoma-in-a-patient-with-rheumatoid-arthritis-a-very-rare-case
#1
Masao Hagihara, Toru Mese, Shin Ohara, Jian Hua, Shiro Ide, Morihiro Inoue
we herein report a rare case of methotrexate (MTX)-associated intravascular large B-cell lymphoma (IVLBCL) in a man with rheumatoid arthritis. Two episodes of a fever of unknown origin accompanied by elevated levels of serum lactate dehydrogenase and the soluble interleukin-2 receptor occurred within a year, so the patient was suspected of having an MTX-associated lymphoproliferative disorder. His clinical symptoms resolved after the cessation of MTX. However, after treatment with iguratimod, another disease-modified anti-rheumatic drug, markedly similar symptoms recurred, and random skin biopsies resulted in a diagnosis of IVLBCL...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29767679/recurrent-cytogenetic-abnormalities-in-intravascular-large-b-cell-lymphoma
#2
Matthew M Klairmont, Jinjun Cheng, Mike G Martin, Joel F Gradowski
Objectives: Data characterizing the cytogenetic landscape of intravascular large B-cell lymphoma (ILBCL) are limited. Here, we developed a comprehensive karyotypic data set to identify recurrent cytogenetic abnormalities in ILBCL. Methods: Cases of ILBCL with complete cytogenetic analysis were identified from an institutional database and the literature. The combined data were systematically reviewed for the presence of recurrent abnormalities. Results: Four new cases were identified and combined with 25 karyotypes previously published in the literature...
May 14, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29756305/did-you-miss-me-a-subtle-case-of-intravascular-large-b-cell-lymphoma
#3
Sanjay Patel, Yi Li, Jacob E Berchuck, James Cunningham, Annette Kim, Olga Pozdnyakova
No abstract text is available yet for this article.
May 13, 2018: American Journal of Hematology
https://www.readbyqxmd.com/read/29737107/-intravascular-large-b-cell-lymphoma-a-clinical-analysis-of-17-cases
#4
Jin-Jun Yang, Xin-Chuan Chen, Yun Tang, Kai Shen, Li-Ping Xie, Ting Liu
OBJECTIVE: To analyze the clinical features,response to therapy and prognosis of intravascular large B-cell lymphoma (IVLBCL). METHODS: The clinical data of 17 cases with IVLBCL were retrospectively reviewed,and survival analysis was conducted. RESULTS: The study involved 10 males and 7 females of IVLBCL with a mean age of 53 years old. The most common symptom of the disease was recurrent fever (76.5%). The lymphoma was mainly observed in bone marrow (64...
January 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29719020/primary-cutaneous-b-cell-lymphomas-clinical-and-histopathologic-features-differential-diagnosis-and-treatment
#5
Steven T Chen, Jeffrey Barnes, Lyn Duncan
Cutaneous B-cell lymphomas (CBCLs) are a heterogeneous group of diseases that can have variable presentations, prognoses, and treatments. The proper identification of a CBCL hinges on proper histopathologic and clinical evaluation. Comprising 25% to 30% of the primary cutaneous lymphomas, incident cases of CBCL are rare. Given the variable natural history of the CBCL, proper classification is critical so that patients are treated appropriately. CBCLs can be divided into 2 main groups: indolent and aggressive...
March 2018: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29707378/serial-chest-ct-findings-of-intravascular-large-b-cell-lymphoma-of-the-lungs
#6
Eun Jung Choi, Gong Yong Jin, Myoung Ja Chung
No abstract text is available yet for this article.
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29686966/a-rare-case-of-suspected-intravascular-large-b-cell-lymphoma-forming-nodular-masses-in-the-brain-and-around-the-prostate-and-seminal-vesicle
#7
Takuto Ogasawara, Yoshinori Ikehata, Ryuichi Kato, Noriomi Miyao, Yasuhiro Konishi, Shinichiro Kon
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). Furthermore, tumorigenesis is extremely rare. An 80-year-old man was admitted to our hospital with nervous symptoms. Imaging tests showed a brain tumor and mass lesions in the seminal vesicle and retroperitoneum. Transrectal biopsy of the seminal vesicle helped diagnose the patient with DLBCL. The patient's general status deteriorated rapidly, and he died on the 23rd day after admission. An autopsy was performed and the pathological diagnosis was DLBCL, specifically suspected as IVLBCL, with nodular masses in the brain and seminal vesicle...
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29575593/utility-of-autopsy-brain-imprint-and-squash-cytology-for-detection-of-lymphoma-leukemia-emboli-in-select-patients-presenting-with-rapid-decline-in-mental-status
#8
Asangi R Kumarapeli, Murat Gokden
Central nervous system (CNS) hematologic malignancies, whether primary or secondary, are uncommon and their clinical presentations vary. Intravascular lymphoma (IVL) is a very rare, aggressive systemic malignancy that is often difficult to diagnose and susceptible to early CNS involvement. Blast crisis in myeloid leukemias can cause widespread neoplastic emboli. Here, we report two adult patients (72 years and 22 years of age) who presented with altered mental status followed by rapid decline in their conditions leading to death...
March 25, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29569516/intravascular-large-b-cell-lymphoma-within-a-thyroid-nodule-a-diagnostic-pitfall
#9
Yevgeniy Linnik, Catherine Nicka, Frederick Lansigan, Eric Loo, Xiaoying Liu
Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large B-cell lymphoma, where the neoplastic lymphoid proliferation resides predominantly within the lumens of blood vessels but with no or few circulating neoplastic cells in the peripheral circulation. Focal or subtle involvement in some cases can cause the diagnosis to be misinterpreted or even overlooked, delaying the initiation of appropriate treatment. Our report focuses on a 78-year-old woman with a progressively enlarging thyroid mass, verified by ultrasound...
March 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29568849/intravascular-large-b-cell-lymphoma-presenting-as-panniculitis-clinically-a-case-report
#10
Yee Wei Phoon, Xuling Lin, T Thirumoorthy, Soo Yong Tan, Hwei Yee Lee, Soon Thye Lim, Haur Yueh Lee
No abstract text is available yet for this article.
March 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29541829/-clinical-and-pathological-characteristics-of-intravascular-lymphomas
#11
REVIEW
L Abraham, H Kreipe, P Raab, K Hussein
Intravascular B‑cell lymphomas (IVL) are rare neoplasms that can manifest at any age (mean age ~62-63 years). About half of the cases are associated with Epstein-Barr virus. The most common sites of manifestation are the brain, skin, and bone marrow. The diagnosis is difficult due to unspecific clinical presentation and laboratory changes. FACS (fluorescence-activated cell sorting) and clonality analysis from peripheral blood and radiological findings are often not diagnostic. The most sensitive and most specific diagnostic method is the histopathological and immunohistochemical evaluation of a tissue biopsy...
May 2018: Der Pathologe
https://www.readbyqxmd.com/read/29532696/kaposi-sarcoma-with-coexisting-intravascular-lymphoma
#12
Dayne Ashman, Liron Pantanowitz
No abstract text is available yet for this article.
March 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29514783/high-prevalence-of-myd88-and-cd79b-mutations-in-intravascular-large-b-cell-lymphoma
#13
LETTER
Anne M R Schrader, Patty M Jansen, Rein Willemze, Maarten H Vermeer, Anne-Marie Cleton-Jansen, Sebastiaan F Somers, Hendrik Veelken, Ronald van Eijk, Willem Kraan, Marie José Kersten, Michiel van den Brand, Wendy B C Stevens, Daphne de Jong, Myrurgia Abdul Hamid, Bea C Tanis, Eduardus F M Posthuma, Marcel Nijland, Arjan Diepstra, Steven T Pals, Arjen H G Cleven, Joost S P Vermaat
No abstract text is available yet for this article.
May 3, 2018: Blood
https://www.readbyqxmd.com/read/29505426/intralymphatic-spread-is-a-rare-finding-associated-with-poor-prognosis-in-diffuse-large-b-cell-lymphoma-with-extranodal-involvements
#14
Chieh-Lung Cheng, Yung-Cheng Su, Tsu-Yi Chao, Chung-Wu Lin, Sheng-Chieh Chou, Ming Yao, Sung-Hsin Kuo, Shan-Chi Yu
Intralymphatic spread is common in solid cancers, but has been rarely studied in lymphomas. Review of 635 extranodal specimens from 475 diffuse large B-cell lymphoma (DLBCL) patients revealed intralymphatic spread in 10 surgical resection specimens from 10 patients including 9 de novo DLBCLs and 1 Richter transformation. The prevalence in de novo DLBCL with extranodal involvements was 1.65%. The most common involved site of intralymphatic spread was the gastrointestinal tract, followed by the female genital tract and breasts...
May 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29472348/liquid-biopsy-for-the-identification-of-intravascular-large-b-cell-lymphoma
#15
Yasuhito Suehara, Mamiko Sakata-Yanagimoto, Keiichiro Hattori, Toru Nanmoku, Takayoshi Itoh, Daisuke Kaji, Go Yamamoto, Yoshiaki Abe, Kentaro Narita, Masami Takeuchi, Kosei Matsue, Taiki Sato, Masayuki Noguchi, Naoko Baba, Tatsuhiro Sakamoto, Manabu Kusakabe, Naoki Kurita, Takayasu Kato, Yasuhisa Yokoyama, Hidekazu Nishikii, Naoshi Obara, Yuichi Hasegawa, Shigeru Chiba
"-".
February 22, 2018: Haematologica
https://www.readbyqxmd.com/read/29467882/primary-pulmonary-intravascular-large-b-cell-lymphoma-a-report-of-three-cases-and-literature-review
#16
Yingwei Zhang, Lintao Bi, Yuying Qiu, Tingting Zhao, Mengshu Cao, Jingjing Ding, Fanqing Meng, Hourong Cai
The present study aimed to investigate the clinicopathological features of primary intravascular large B-cell lymphoma (IVLBCL) of the lung. The clinical and histopathological data of three patients, and the literature was reviewed. The Ethics Committees of Drum Tower Hospital approved the current study based on the three cases. Fever and respiratory symptoms were the main presenting symptoms. Serum lactate dehydrogenase and C-reactive protein were significantly increased. Diffuse ground glass opacities or nodular consolidations were seen on high resolution computed tomography...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29415979/autopsy-case-report-of-intravascular-large-b-cell-lymphoma-with-neoplastic-pd-l1-expression
#17
Ayako Sakakibara, Yuichiro Inagaki, Eiki Imaoka, Eri Ishikawa, Satoko Shimada, Kazuyuki Shimada, Yuka Suzuki, Shigeo Nakamura, Akira Satou, Kei Kohno
Intravascular large B-cell lymphoma (IVLBCL) is a rare and clinically distinctive entity characterized by the almost exclusive growth of large cells within the lumen of blood vessels in particular capillaries. Reports of this peculiar disease, do not commonly address the PD-L1 expression on IVLBCL tumor cells. Here, we describe a 51-year-old Japanese woman who presented with rapidly progressive cognitive decline and higher brain dysfunction. CT scan and MRI revealed multiple ischemic foci in the cerebral hemispheres, ground-glass opacity in the lungs, and splenomegaly...
March 16, 2018: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/29391332/intravascular-large-b-cell-lymphoma-of-the-gallbladder
#18
Bülent Çetin, Nalan Akyürek, Yavuz Metin, Feryal Karaca, İrem Bilgetekin, Ahmet Ozet
No abstract text is available yet for this article.
February 2, 2018: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/29387769/random-skin-biopsy-for-diagnosis-of-intravascular-large-b-cell-lymphoma-in-a-patient-with-hypoxemia-and-normal-lung-imaging
#19
Athiphat Banjongjit, Kanokphorn Chiratikarnwong, Pirun Saelue, Siripan Sangmala, Sauvarat Auepemkiate, Kanita Kayasut
No abstract text is available yet for this article.
March 2018: JAAD Case Reports
https://www.readbyqxmd.com/read/29378736/intravascular-lymphoma-presenting-with-postural-hypotension
#20
Catharine Pearce, Suzy Hope, Joseph Butchart
An 84-year-old woman presented with severe postural hypotension. Further assessment revealed weight loss, fatigue and fever at night. On examination, she had bilateral skin lesions on the inner thighs and skin biopsy revealed intravascular high grade B cell lymphoma. This was successfully treated with curative chemotherapy. The cause of the postural hypotension in this case was felt likely to be autonomic neuropathy caused by neurovascular infiltration by intravascular lymphoma. Treatment of the lymphoma has resolved the postural hypotension, although some symptoms of postural instability persist...
January 29, 2018: BMJ Case Reports
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