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https://www.readbyqxmd.com/read/28936684/kinematics-of-mobile-bearing-unicompartmental-knee-arthroplasty-compared-to-native-results-from-an-in-vitro-study
#1
Geert Peersman, Josh Slane, Philippe Vuylsteke, Susanne Fuchs-Winkelmann, Philipp Dworschak, Thomas Heyse, Lennart Scheys
INTRODUCTION: Fixed-bearing unicompartmental knee arthroplasty (UKA) closely replicates native knee kinematics. As few studies have assessed kinematics following mobile-bearing (MB) UKA, the current study aimed to investigate whether MB UKA preserves natural knee kinematics. MATERIALS AND METHODS: Seven fresh-frozen full-leg cadaver specimens were prepared and mounted in a kinematic rig that allowed all degrees of freedom at the knee. Three motion patterns, passive flexion-extension (0°-110° flexion), open-chain extension (5°-70° flexion) and squatting (30°-100° flexion), were performed pre- and post-implantation of a medial MB UKA and compared in terms of rotational and translational knee joint kinematics in the different anatomical planes, respectively...
September 21, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28933489/drop-friction-on-liquid-infused-materials
#2
Armelle Keiser, Ludovic Keiser, Christophe Clanet, David Quéré
We discuss in this paper the nature of the friction generated as a drop glides on a textured material infused by another liquid. Different regimes are found, depending on the viscosities of both liquids. While a viscous drop simply obeys a Stokes-type friction, the force opposing a drop moving on a viscous substrate becomes non-linear in velocity. A liquid on an infused material is surrounded by a meniscus, and this specific feature is proposed to be responsible for the special frictions observed on both adhesive and non-adhesive substrates...
September 21, 2017: Soft Matter
https://www.readbyqxmd.com/read/28933331/-comparison-of-the-arthroscopic-finding-in-the-knee-joint-and-the-mri-retrospective-study
#3
K Šimeček, P Látal, J Duda, M Šimeček
PURPOSE OF THE STUDY Our retrospective study presents the comparison of the preoperative magnetic resonance imaging of the knee joint - MRI - and the arthroscopic finding - ASC. Its aim is to find out how a positive or a negative finding of MRI corresponds with the operative finding and how much the experience of radiologist contributes to the conformity. MATERIAL AND METHODS The MRI findings of knee joints treated surgically at two departments in 2013 and 2014 were assessed. The MRI was performed in a total of 470 patients who subsequently underwent an arthroscopic surgery...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28930832/early-central-and-peripheral-corneal-microstructural-changes-in-type-2-diabetes-mellitus-patients-identified-using-in-vivo-confocal-microscopy-a-case-control-study
#4
Jing-Hao Qu, Lei Tian, Xiao-Yu Zhang, Xu-Guang Sun
The aim of this study was to find early central and peripheral corneal microstructural changes in healthy subjects and type 2 diabetes mellitus (T2DM) patients with/without cornea fluorescein dot staining.This is a prospective case-control study of T2DM patients with/without cornea fluorescein dot staining. Age, sex, duration of diabetes, and serum glycosylated hemoglobin A1c (HbA1c) levels were recorded. Keratograph 5 M (K5 M) and in vivo confocal microscopy were performed on all subjects. The cornea was divided into 5 zones: central, superior, temporal, nasal, and inferior...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28928664/yougui-pills-attenuate-cartilage-degeneration-via-activation-of-tgf-%C3%AE-smad-signaling-in-chondrocyte-of-osteoarthritic-mouse-model
#5
Lei Zhang, Ping-Er Wang, Jun Ying, Xing Jin, Cheng Luo, Taotao Xu, Shibing Xu, Rui Dong, Luwei Xiao, Peijian Tong, Hongting Jin
Yougui pills (YGPs) have been used for centuries in the treatment of Chinese patients with Kidney-Yang Deficiency Syndrome. Despite the fact that the efficiency of YGPs on treating osteoarthritis has been verified in clinic, the underlying mechanisms are not totally understood. The present study observes the therapeutic role of YGPs and mechanisms underlying its chondroprotective action in osteoarthritic cartilage. To evaluate the chondroprotective effects of YGPs, we examined the impact of orally administered YGPs in a model of destabilization of the medial meniscus (DMM)...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28925663/top-poems-of-2016-consistent-with-the-principles-of-the-choosing-wisely-campaign
#6
Roland Grad, Mark H Ebell
A challenge in the Choosing Wisely campaign is to identify low-value clinical actions supported by high-quality evidence. We applied a method based on crowdsourcing the Daily POEM (patient-oriented evidence that matters) to identify low-value clinical actions from research studies consistent with the principles of Choosing Wisely. In 2016, we analyzed an average of 1,382 questionnaires on 265 unique POEMs delivered to physician members of the Canadian Medical Association. From these questionnaires, we identified the POEMs ranking highest on one questionnaire item directly linked to reducing overdiagnosis or overtreatment...
August 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28925568/the-fibular-meniscus-of-the-kangaroo-as-an-adaptation-against-external-tibial-rotation-during-saltatorial-locomotion
#7
Adrian C Miller, Martin A Cake, Natalie M Warburton
The kangaroo knee is, as in other species, a complex diarthrodial joint dependent on interacting osseous, cartilaginous and ligamentous components for its stability. While principal load bearing occurs through the femorotibial articulation, additional lateral articulations involving the fibula and lateral fabella also contribute to the functional arrangement. Several fibrocartilage and ligamentous structures in this joint remain unexplained or have been misunderstood in previous studies. In this study, we review the existing literature on the structure of the kangaroo 'knee' before providing a new description of the gross anatomical and histological structures...
September 19, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28922015/over-the-top-acl-reconstruction-plus-extra-articular-lateral-tenodesis-with-hamstring-tendon-grafts-prospective-evaluation-with-20-year-minimum-follow-up
#8
Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Alberto Grassi, Tommaso Roberti di Sarsina, Federico Raggi, Cecilia Signorelli, Francisco Urrizola, Paolo Spinnato, Eugenio Rimondi, Maurilio Marcacci
BACKGROUND: There are few published studies with very long-term follow-up of combined intra- and extra-articular anterior cruciate ligament (ACL) reconstruction. PURPOSE: To analyze clinical and radiographic outcomes of over-the-top ACL reconstruction plus extra-articular lateral tenodesis with autologous hamstrings at minimum 20-year follow-up. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Of 60 originally eligible patients who underwent over-the-top ACL reconstruction with double-stranded hamstring tendon (leaving intact graft tibial insertions) and extra-articular lateral plasty (performed with the remnant part of tendons), 52 were prospectively evaluated at a minimum 20-year follow-up (mean follow-up, 24 years; 41 men, 11 women; mean age at time of surgery, 25...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28921609/biomarkers-for-equine-joint-injury-and-osteoarthritis
#9
REVIEW
C Wayne McIlwraith, Christopher E Kawcak, David D Frisbie, Christopher B Little, Peter D Clegg, Mandy J Peffers, Morten A Karsdal, Stina Ekman, Sheila Laverty, Richard A Slayden, Linda J Sandell, L Stefan Lohmander, Virginia B Kraus
We report the results of a symposium aimed at identifying validated biomarkers that can be used to complement clinical observations for diagnosis and prognosis of joint injury leading to equine osteoarthritis (OA). Biomarkers might also predict pre-fracture change that could lead to catastrophic bone failure in equine athletes. The workshop was attended by leading scientists in the fields of equine and human musculoskeletal biomarkers to enable cross-disciplinary exchange and improve knowledge in both. Detailed proceedings with strategic planning was written, added to, edited and referenced to develop this manuscript...
September 16, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28920170/meniscal-extrusion-seen-on-ultrasonography-affects-the-development-of-radiographic-knee-osteoarthritis-a-3-year-prospective-cohort-study
#10
Daisuke Chiba, Shugo Maeda, Eiji Sasaki, Seiya Ota, Shigeyuki Nakaji, Eiichi Tsuda, Yasuyuki Ishibashi
The objective of this study is to determine whether meniscal extrusion (ME) of the medial meniscus on ultrasonography affects knee osteoarthritis (KOA) progression during 3-year follow-up. Two hundred seventy volunteers (70 men, 200 women; mean age 60.5 years) participated. Weight-bearing radiographs were evaluated. All subjects had medial radiographic KOA (Kellgren-Lawrence grade [KLG], ≥ 2) in at least one knee at baseline (BL). KLG 2 was defined as moderate KOA (MKOA); KLG 3 and 4 were defined as severe KOA (SKOA)...
September 17, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28919498/accelerated-return-to-sport-after-acl-reconstruction-and-early-knee-osteoarthritis-features-at-1-year-an-exploratory-study
#11
Adam G Culvenor, Brooke E Patterson, Ali Guermazi, Hayden G Morris, Timothy S Whitehead, Kay M Crossley
BACKGROUND: A timely return to competitive sport is a primary goal of anterior cruciate ligament reconstruction (ACLR). It is not known if an accelerated return-to-sport increases the risk of early-onset knee osteoarthritis (KOA). OBJECTIVE: To determine whether an accelerated return-to-sport post-ACLR (i.e., <10 months) is associated with increased odds of early KOA features on MRI 1-year post-surgery, and to evaluate the relationship between an accelerated return-to-sport and early KOA features stratified by type of ACL injury (isolated or concurrent chondral/meniscal injury) and lower-limb function (good or poor)...
September 14, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28919183/impact-of-oral-vitamin-d-supplementation-on-the-ocular-surface-in-people-with-dry-eye-and-or-low-serum-vitamin-d
#12
Chih-Huang Yang, Julie Albietz, Damien G Harkin, Michael G Kimlin, Katrina L Schmid
PURPOSE: To determine the possible association between serum vitamin D levels and dry eye symptoms, and the impact of an oral vitamin D supplement. METHODS: Three linked studies were performed. (i) 29 older adult participants, (ii) 29 dry eyed participants, and (iii) 2-month vitamin D supplementation for 32 dry eyed/low serum vitamin D levelled participants. All participants were assessed by the Ocular Surface Diseases Index (OSDI) to determine dry eye symptoms, and the phenol red thread test (PRT) and/or Schirmer's tear test, tear meniscus height, non-invasive tear break up time, grading ocular surface redness and fluorescein staining of the cornea to detect the tear quality and ocular surface conditions...
September 11, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28918786/-treatment-of-meniscal-pathology
#13
Martin Wyman Rathcke, Martin Lind, Morten Ilum Boesen, Nis Nissen, Anders Ploug Boesen, Bjarne Mygind-Klavsen, Per Hölmich
The menisci play a major role in knee function regarding joint movement, stability, load distribution and load transmission. Injuries to the menisci cause pain, and meniscal tears are a common reason for patient referral. In Denmark, partial meniscectomy increased significantly until 2010, and several studies have questioned the long-term effect of meniscectomy as an overall procedure. A Danish national clinical guideline on knee meniscal pathology was published in May 2016, and this article is a short summary of updated knowledge on meniscal pathology and relevant conclusions from the guideline...
September 18, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28917521/midterm-results-of-combined-intra-and-extra-articular-acl-reconstruction-compared-to-historical-acl-reconstruction-data-multicenter-study-of-the-francophone-society-of-arthroscopy
#14
P Imbert, S Lustig, C Steltzlen, C Batailler, P Colombet, F Dalmay, S Bertiaux, P D'ingrado, F P Ehkirch, M L Louis, R Pailhé, J C Panisset, B Schlaterrer, B Sonnery-Cottet, L Sigwalt, D Saragaglia, C Lutz
INTRODUCTION: During anterior cruciate ligament (ACL) reconstruction procedures, anterolateral reconstruction (ALR) can also be performed to improve the knee's rotational stability. However, the effectiveness of this supplemental technique and its impact on the risk of retears and on the onset of secondary degenerative changesare controversial. HYPOTHESIS: ALR improves control over the pivot shift, reduces the retear risk and delays the appearance of secondary degenerative lesions...
September 13, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28915521/comparative-analysis-of-gene-expression-between-cartilage-and-menisci-in-early-phase-osteoarthritis-of-the-knee-an-animal-model-study
#15
Jun Endo, Takahisa Sasho, Ryuichiro Akagi, Yuta Muramatsu, Atsuya Watanabe, Yorikazu Akatsu, Taisuke Fukawa, Masamichi Tahara, Satoshi Yamaguchi
No abstract text is available yet for this article.
September 15, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28915439/alpha-mangostin-suppresses-interleukin-1%C3%AE-induced-apoptosis-in-rat-chondrocytes-by-inhibiting-the-nf-%C3%AE%C2%BAb-signaling-pathway-and-delays-the-progression-of-osteoarthritis-in-a-rat-model
#16
Tianlong Pan, Rong Chen, Dengying Wu, Ningyu Cai, Xuchao Shi, Bin Li, Jun Pan
Osteoarthritis (OA) is a chronic degenerative joint disease that is characterized by progressive joint dysfunction and pain. Apoptosis and catabolism in chondrocytes play critical roles in the development of OA. Alpha-Mangostin (α-MG), one of the main components of the mangosteen, has been reported to have anti-apoptotic, anti-inflammatory and antioxidant effects. We investigated the therapeutic effects of α-MG on OA through experiments on rat chondrocytes in vitro and in a rat model of OA induced by destabilization of the medial meniscus (DMM)...
September 12, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28913685/-ramp-lesions-tips-and-tricks-in-diagnostics-and-therapy
#17
REVIEW
R Seil, A Hoffmann, S Scheffler, D Theisen, C Mouton, D Pape
There is an increasing biomechanical and anatomical understanding of the different types of meniscal lesions. Lesions of the posterior part of the medial meniscus in the meniscosynovial area have recently received increased attention. They generally occur in association with anterior cruciate ligament (ACL) injuries. They are often missed ("hidden lesions") due to the fact that they cannot be seen by routine anterior arthroscopic inspection. Furthermore, meniscosynovial lesions play a role in anteroposterior knee laxity and, as such, they may be a cause of failure of ACL reconstruction or of postoperative persistent laxity...
September 14, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28910961/paeonol-alleviates-interleukin-1%C3%AE-induced-inflammatory-responses-in-chondrocytes-during-osteoarthritis
#18
Mingran Liu, Shuqiang Zhong, Ruifeng Kong, Hong Shao, Chunyan Wang, Hongying Piao, Wentao Lv, Xiaojie Chu, Yan Zhao
Interleukin-1β (IL-1β)-induced inflammatory responses in chondrocytes play an important role in the pathogenesis of osteoarthritis (OA). Searching medicines that affect IL-1β-mediated chondrocytes function is critical in developing therapies for OA. Paeonol, as an important component in traditional Chinese medicine, has anti-inflammatory activity and can offer therapy for a multitude of inflammatory-related diseases. The purpose of this study was to investigate whether paeonol could alleviate the progression of OA through inhibition of IL-1β-induced inflammatory responses in chondrocytes...
September 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28910571/factors-that-influence-tear-meniscus-area-and-conjunctivochalasis-the-singapore-indian-eye-study
#19
Stanley Poh, Ryan Lee, Jennifer Gao, Carin Tan, Preeti Gupta, Charumathi Sabanayagam, Ching-Yu Cheng, Tien-Yin Wong, Louis Tong
PURPOSE: Assessment of tear film and conjunctiva is critical to define presence and severity of ocular surface disease. We aimed to characterize tear meniscus area (TMA) and conjunctivochalasis by anterior segment optical coherence tomography (ASOCT) in population-based patients and identify potential factors associated with low TMA and severe conjunctivochalasis. METHODS: Study subjects were enrolled from The Singapore Indian Eye Study, a population-based study of Asian Indian in Singapore...
September 14, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28910532/roles-of-wettability-and-supercooling-in-cyclopentane-hydrate-spreading-over-a-substrate
#20
Abdelhafid Touil, Daniel Broseta, Nelly Hobeika, Ross Brown
We use transmission optical microscopy to observe cyclopentane hydrate growth in sub-mm, open glass capillaries, mimicking cylindrical pores. The capillary is initially loaded with water and the guest fluid (cyclopentane) and thus possesses three menisci, that between water and cyclopentane (CP) in the middle, and two menisci with the vapors at the ends. At temperatures T below the equilibrium temperature Teq ∼ 7°C, the hydrate nucleates on the water-CP meniscus, rapidly coating it with an immobile, polycrystalline crust...
September 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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