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https://www.readbyqxmd.com/read/28545179/the-efficacy-of-meniscal-treatment-associated-with-lateral-tibial-plateau-fractures
#1
Hyun-Joo Park, Hui-Du Lee, Jin Ho Cho
Purpose: The purpose of this study was to examine the incidence of lateral meniscal tears associated with lateral tibial plateau fractures and report the clinical outcomes of meniscal treatment with internal fixation of fractures. Materials and Methods: All lateral tibial plateau fractures (Schatzker types II and III) in skeletally mature patients treated operatively at our institution between January 2010 and February 2016 were included. All patients underwent open reduction and internal fixation using a buttress plate or cancellous screws...
June 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28544605/assessment-of-meibomian-glands-and-tear-film-in-post-refractive-surgery-patients
#2
Ji Won Jung, Jung Yong Kim, Hee Seung Chin, Young Ju Suh, Tae-Im Kim, Kyoung Yul Seo
IMPORTANCE: Corneal refractive surgery may impact meibomian gland and tear film in post-refractive surgery patients. BACKGROUND: To compare ocular surface parameters between post-refractive surgery patients and normal controls. DESIGN: Cross-sectional single center study PARTICIPANTS: A total of 120 eyes of 120 subjects were divided into three groups: (i) 60 controls and 60 patients underwent corneal refractive surgery at least 12 months ago; (ii) 30 post-laser in-situ keratomileusis (LASIK) patients and (iii) 30 post-laser epithelial keratomileusis (LASEK)/photo-refractive keratectomy (PRK) patients...
May 22, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28544596/deletion-of-the-prostaglandin-d2-receptor-dp1-exacerbates-aging-associated-and-instability-induced-osteoarthritis
#3
Yassine Ouhaddi, Sarah-Salwa Nebbaki, Lauris Habouri, Hassan Afif, Bertrand Lussier, Mohit Kapoor, Shuh Narumiya, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Mohamed Benderdour, Hassan Fahmi
OBJECTIVE: The D prostanoid receptor 1 (DP1), a receptor for prostaglandin D2 (PGD2 ), plays important roles in inflammation and cartilage metabolism. However, its role in the pathogenesis of osteoarthritis (OA) remains unknown. We undertook this study to explore the roles of DP1 in the development of OA and to evaluate the efficacy of a DP1 selective agonist in the treatment of OA. METHODS: We compared the development of aging-associated OA and destabilization of the medial meniscus (DMM)-induced OA in DP1-deficient (DP1-/-) and wild-type (WT) mice...
May 23, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28543035/owner-assessment-of-the-outcome-of-tibial-plateau-levelling-osteotomy-without-meniscal-evaluation-for-treatment-of-naturally-occurring-cranial-cruciate-ligament-rupture-130-cases-2009-to-2013
#4
S Bureau
OBJECTIVE: To evaluate long-term surgical outcome and chronic pain in dogs suffering from naturally occurring cranial cruciate ligament rupture treated by tibial plateau levelling osteotomy without meniscal evaluation. MATERIALS AND METHODS: In this retrospective clinical study, data from surgical records of dogs with cranial cruciate ligament rupture that underwent tibial plateau levelling osteotomy without meniscal evaluation between August 2009 and November 2013 were reviewed...
May 25, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28542363/tnf%C3%AE-promotes-proliferation-of-human-synovial-mscs-while-maintaining-chondrogenic-potential
#5
Mikio Shioda, Takeshi Muneta, Kunikazu Tsuji, Mitsuru Mizuno, Keiichiro Komori, Hideyuki Koga, Ichiro Sekiya
Synovial mesenchymal stem cells (MSCs) are a candidate cell source for cartilage and meniscus regeneration. If we can proliferate synovial MSCs more effectively, we can expand clinical applications to patients with large cartilage and meniscus lesions. TNFα is a pleiotropic cytokine that can affect the growth and differentiation of cells in the body. The purpose of this study was to examine the effect of TNFα on proliferation, chondrogenesis, and other properties of human synovial MSCs. Passage 1 human synovial MSCs from 2 donors were cultured with 2...
2017: PloS One
https://www.readbyqxmd.com/read/28542084/effects-of-diquafosol-ophthalmic-solution-on-quality-of-life-in-dry-eye-assessed-using-the-dry-eye-related-quality-of-life-score-questionnaire-effectiveness-in-patients-while-reading-and-using-visual-display-terminals
#6
Tsugiaki Utsunomiya, Atsushi Kawahara, Kazuomi Hanada, Akitoshi Yoshida
PURPOSE: Diquafosol ophthalmic solution improves objective findings in the ocular surface and subjective symptoms in patients with dry eye. The Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire was developed to assess dry eye symptoms and their effects on quality of life. However, because little research using the DEQS has been reported, we evaluated the effects of diquafosol ophthalmic solution on ocular surface findings and quality of life using the DEQS in patients with dry eye...
May 23, 2017: Cornea
https://www.readbyqxmd.com/read/28541035/three-dimensional-printing-of-silver-microarchitectures-using-newtonian-nanoparticle-inks
#7
Sanghyeon Lee, Jung Hyun Kim, Muhammad Wajahat, Hwakyung Jeong, Won Suk Chang, Sung Ho Cho, Ji Tae Kim, Seung Kwon Seol
Although three-dimensional (3D) printing has recently emerged as a technology to potentially bring about the next industrial revolution, the limited selection of usable materials restricts its use to simple prototyping. In particular, metallic 3D printing with submicrometer spatial resolution is essential for the realization of 3D-printed electronics. Herein, a meniscus-guided 3D printing method that exploits a low-viscosity (∼7 mPa·s) silver nanoparticle (AgNP) ink meniscus with Newtonian fluid characteristics (which is compatible with conventional inkjet printers) to fabricate 3D silver microarchitectures is reported...
May 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28539595/deletion-of-runx2-in-articular-chondrocytes-decelerates-the-progression-of-dmm-induced-osteoarthritis-in-adult-mice
#8
Lifan Liao, Shanxing Zhang, Jianhong Gu, Takeshi Takarada, Yukio Yoneda, Jian Huang, Lan Zhao, Chun-do Oh, Jun Li, Baoli Wang, Meiqing Wang, Di Chen
Runx2 may play an important role in development of osteoarthritis (OA). However, the specific role of Runx2 in articular chondrocyte function and in OA development in adult mice has not been fully defined. In this study, we performed the destabilization of the medial meniscus (DMM) surgery at 12-week-old mice to induce OA in adult Runx2 (Agc1CreER) mice, in which Runx2 was specifically deleted in Aggrecan-expressing chondrocytes by administering tamoxifen at 8-weeks of age. Knee joint samples were collected 8- and 12-weeks post-surgery and analyzed through histology, histomorphometry and micro-computed tomography (μCT)...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536855/rotational-laxity-control-by-the-anterolateral-ligament-and-the-lateral-meniscus-is-dependent-on-knee-flexion-angle-a-cadaveric-biomechanical-study
#9
Timothy Lording, Gillian Corbo, Dianne Bryant, Timothy A Burkhart, Alan Getgood
BACKGROUND: Injury to the anterolateral ligament (ALL) has been reported to contribute to high-grade anterolateral laxity after anterior cruciate ligament (ACL) injury. Failure to address ALL injury has been suggested as a cause of persistent rotational laxity after ACL reconstruction. Lateral meniscus posterior root (LMPR) tears have also been shown to cause increased internal rotation of the knee. QUESTIONS/PURPOSES: The purpose of this study was to determine the functional relationship between the ALL and LMPR in the control of internal rotation of the ACL-deficient knee...
May 23, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28536794/good-clinical-results-can-be-obtained-along-with-reduced-risk-of-tunnel-communication-with-a-new-technique-in-concomitant-meniscus-transplantation-and-acl-reconstruction
#10
Murat Bozkurt, Mesut Tahta, Mustafa Akkaya, Cetin Isik, Safa Gursoy
PURPOSE: The purpose of this study was to introduce our technical modification for concomitant meniscus transplantation and ACL reconstruction with preliminary results of our cases. METHODS: The current study comprised of two sections: first is the cadaveric study of 20 specimens. The distances between tunnel entry and exit points of tunnels for 27 meniscal transplants and ACL reconstruction in CT slices were measured. The second section was evaluation of our cases including six patients...
May 23, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28536729/clinics-in-diagnostic-imaging-177-medical-meniscus-bucket-handle-tear-with-medial-oblique-meniscomeniscal-ligament
#11
Poh Lye Paul See
A 29-year-old man with a previous football injury to his left knee presented with pain of the same knee. The patient twisted it as he was turning a corner quickly while going up the stairs, leading to internal rotation of his femur on his tibia with his knee in flexion. MR imaging revealed a bucket-handle tear of the medial meniscus, as well as a complete tear of the anterior cruciate ligament. However, image interpretation was complicated by the presence of a medial oblique meniscomeniscal ligament, a rare normal variant among intermeniscal ligaments of the knee...
May 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28534321/does-anatomic-single-bundle-acl-reconstruction-using-hamstring-autograft-produce-anterolateral-meniscal-root-tearing
#12
Sebastián Irarrázaval, Angel Masferrer-Pino, Maximiliano Ibañez, Tamer M A Shehata, María Naharro, Joan C Monllau
BACKGROUND: To determine if tibial tunnel reaming during anatomic single-bundle anterior cruciate ligament (ACL) reconstruction using hamstring autograft can result in anterolateral meniscal root injury, as diagnosed by magnetic resonance imaging (MRI). METHODS: A case series of 104 primary anatomic single-bundle ACL reconstructions using hamstring autograft was retrospectively reviewed. Pre- and post-operative (>1 year) MRIs were radiologically evaluated for each patient, with a lateral meniscus extrusion > 3 mm at the level of the medial collateral ligament midportion on a coronal MRI, to establish anterolateral meniscal root injury...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28533596/the-ratio-of-medial-and-lateral-hamstring-muscle-thickness-does-not-correlate-with-the-lateral-tibial-rotation-angle-in-the-standing-position-in-healthy-young-adults
#13
Dong-Soo Lee, Sung-Dae Choung, Seung-Won Lee, Hye Rim Suh, Jae-Hoon Shim
[Purpose] To investigate the relationship between the lateral tibial rotation angle during knee joint flexion and the medial and lateral hamstring muscle thickness ratio during knee joint extension while resting, doing nothing, in upright standing position. The lateral tibial torsion is an important factor of orthopedic knee joint diseases as well as other weight bearing joint diseases such as osteoarthritis, meniscus syndrome, anterior cruciate ligament rupture, etc. [Subjects and Methods] Thirty healthy young adults participated in this study...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533592/articular-chondrocyte-alignment-in-the-rat-after-surgically-induced-osteoarthritis
#14
Hideaki Takahashi, Hiroyuki Tamaki, Noriaki Yamamoto, Hideaki Onishi
[Purpose] Chondrocytes in articular cartilage are aligned as columns from the joint surface. Notably, loss of chondrocyte and abnormalities of differentiation factors give rise to osteoarthritis (OA). However, the relationship between chondrocyte alignment and OA progression remains unclear. This study was performed to investigate temporal alterations in surgically-induced OA rats. [Subjects and Methods] Thirteen-week-old Wistar rats (n=30) underwent destabilized medial meniscus surgery in their right knee and sham surgery in their left knee...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28532890/fascial-manipulation-%C3%A2-for-persistent-knee-pain-following-acl-and-meniscus-repair
#15
Sannasi Rajasekar, Aurélie Marie Marchand
Fascial Manipulation(®) (FM) is a manual therapy approach for the treatment of musculoskeletal pain. Anomalous fascial tension is common following surgery due to surgical scar, inadequate mobility and fear of movement. Fascial tension may result in pain and loss of mobility. This case report aims at investigating the effectiveness of FM(®) on pain and function in a patient following knee surgery. A 32 years old male patient, with persisting knee pain following anterior cruciate ligament reconstruction (hamstring graft) and meniscal repair, underwent the systematic FM(®) assessment process, the selected centers of coordination of myofascial units were treated...
April 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28530851/chondral-injuries-and-irreparable-meniscal-tears-among-adolescents-with-anterior-cruciate-ligament-or-meniscal-tears-are-more-common-in-patients-with-public-insurance
#16
Ariel A Williams, Nickolas S Mancini, Matthew J Solomito, Carl W Nissen, Matthew D Milewski
BACKGROUND: Access to health care services is a critical component of health care reform and may differ among patients with different types of insurance. Hypothesis/Purpose: The purpose was to compare adolescents with private and public insurance undergoing surgery for anterior cruciate ligament (ACL) and/or meniscal tears. We hypothesized that patients with public insurance would have a delayed presentation from the time of injury and therefore would have a higher incidence of chondral injuries and irreparable meniscal tears and lower preoperative International Knee Documentation Committee (IKDC) scores than patients with private insurance...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28524271/histological-characteristics-of-knee-menisci-in-patients-with-osteoarthritis
#17
D McDaniel, E Tilton, K Dominick, K Flory, T Ernest, J C Johnson, D C Main, P Kondrashov
INTRODUCTION: Existing data indicate knee menisci in patients with osteoarthritis (OA) show tearing, maceration, and fragmentation, but little is known about the change in histological structure. The aim of this study was to evaluate change in the menisci histological structure in patients with clinically diagnosed knee OA. MATERIALS AND METHODS: Fourteen patients undergoing surgical treatment of knee OA (OA group) and 14 cadaveric knees (control group) were assessed...
May 19, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28524144/-new-approaches-to-the-treatment-of-keratoconjunctivitis-sicca
#18
T N Safonova, O V Gladkova, I A Novikov, V I Boev, A A Fedorov
A new method has been developed for the treatment of severe forms of keratoconjunctivitis sicca (KCS) that involves the use of an original cyclosporine A (CyA) saturated soft contact lens (SCL) together with preservative-free artificial tears therapy. AIM: to evaluate the effectiveness of the newly developed treatment for KCS based on the use of medical SCL saturated with 0.05% CyA. MATERIAL AND METHODS: The patients (43 men, 60 eyes) with severe KCS were divided into 2 groups...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28523339/medial-meniscal-extrusion-a-validation-study-comparing-different-methods-of-assessment
#19
Luke D Jones, Stephen J Mellon, Neil Kruger, Andrew P Monk, Andrew J Price, David J Beard
PURPOSE: Longitudinal cohort studies of knee OA aetiology use MRI to assess meniscal extrusion within the same knee at sequential time points. A validated method of assessment is required to ensure that extrusion is measured at the same location within the knee at each time point. Absolute perpendicular extrusion from the tibial edge can be assessed using the reference standard of segmentation of the tibia and medial meniscus. This is labour intensive and unsuitable for large cohorts...
April 21, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28522452/arthroscopic-partial-meniscectomy-versus-placebo-surgery-for-a-degenerative-meniscus-tear-a-2-year-follow-up-of-the-randomised-controlled-trial
#20
Raine Sihvonen, Mika Paavola, Antti Malmivaara, Ari Itälä, Antti Joukainen, Heikki Nurmi, Juha Kalske, Anna Ikonen, Timo Järvelä, Tero Ah Järvinen, Kari Kanto, Janne Karhunen, Jani Knifsund, Heikki Kröger, Tommi Kääriäinen, Janne Lehtinen, Jukka Nyrhinen, Juha Paloneva, Outi Päiväniemi, Marko Raivio, Janne Sahlman, Roope Sarvilinna, Sikri Tukiainen, Ville-Valtteri Välimäki, Ville Äärimaa, Pirjo Toivonen, Teppo Ln Järvinen
OBJECTIVE: To assess if arthroscopic partial meniscectomy (APM) is superior to placebo surgery in the treatment of patients with degenerative tear of the medial meniscus. METHODS: In this multicentre, randomised, participant-blinded and outcome assessor-blinded, placebo-surgery controlled trial, 146 adults, aged 35-65 years, with knee symptoms consistent with degenerative medial meniscus tear and no knee osteoarthritis were randomised to APM or placebo surgery. The primary outcome was the between-group difference in the change from baseline in the Western Ontario Meniscal Evaluation Tool (WOMET) and Lysholm knee scores and knee pain after exercise at 24 months after surgery...
May 18, 2017: Annals of the Rheumatic Diseases
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