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https://www.readbyqxmd.com/read/28811693/beneficial-effect-of-aqueous-garlic-extract-on-inflammation-and-oxidative-stress-status-in-the-kidneys-of-type-1-diabetic-rats
#1
Abolfazl Nasiri, Nasrin Ziamajidi, Roghayeh Abbasalipourkabir, Mohammad Taghi Goodarzi, Massoud Saidijam, Hamid Behrouj, Sara Solemani Asl
One of the most important complications of diabetes is nephropathy. This study investigates the effects of aqueous garlic extract on inflammation and oxidative stress status in the kidneys of diabetic rats. Male rats were divided into four groups- control rats, diabetic rats, garlic extract-treated diabetic rats, garlic extract-treated normal rats. The glucose, urea, uric acid, and creatinine levels were measured in sera using colorimetric methods. To determine the oxidative stress condition in the kidney tissues, total antioxidant capacity (TAC), malondialdehyde (MDA), and total oxidant status (TOS) were measured using colorimetric methods...
July 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/28797988/effects-of-long-term-synbiotic-supplementation-in-addition-to-lifestyle-changes-in-children-with-obesity-related-non-alcoholic-fatty-liver-disease
#2
Murat Çakır, Ayşe Aksel İşbilen, İlker Eyüpoğlu, Elif Sağ, Asım Örem, Tuğba Mazlum Şen, Neşe Kaklıkkaya, Gülay Kaya
BACKGROUND/AIMS: We aimed to analyze the efficiency of a novel treatment approach, long-term synbiotic supplementation, in addition to lifestyle changes in children with non-alcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS: The study included children with NAFLD (n=28) and a healthy control group (n=30). Children with NAFLD were given 1 capsule/day of synbiotics. Anthropometric parameters; biochemical analysis, including ethanol, tumor necrosis factor-α (TNF-α), total oxidant status (TOS) and anti-oxidant status (TAS), zonulin, and fecal calprotectin; and ultrasonographic examination were performed at baseline and 4 months later...
August 9, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28797510/soft-tissue-tumors-rarely-presenting-primary-in-bone-diagnostic-pitfalls
#3
REVIEW
Marta Sbaraglia, Alberto Righi, Marco Gambarotti, Daniel Vanel, Piero Picci, Angelo P Dei Tos
Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. A more accurate morphologic partition is justified based on availability of distinct therapeutic options. An integrated diagnostic approach represents the only way to achieve a correct classification...
September 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28796539/carbonic-anhydrase-i-ii-autoantibodies-and-oxidative-status-in-long-term-follow-up-of-patients-with-crimean-congo-haemorrhagic-fever
#4
Hülya Yilmaz, Uğur Kostakoğlu, Selim Demir, Firdevs Aksoy, Ahmet Menteşe, Süleyman Caner Karahan, İftihar Köksal, Ahmet Alver, Gürdal Yilmaz
CONTEXT: Crimean-Congo haemorrhagic fever (CCHF) is a life-threatening acute febrile haemorrhagic disease. OBJECTIVE: This study was to measure levels of the oxidative stress biomarkers malondialdehyde (MDA), total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) and of CA I-II autoantibodies as biomarkers for autoimmunity and course of disease in patients with CCHF. METHODS: Seventy CCHF patients and 39 healthy control volunteers were included in the study...
August 10, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28781771/the-impact-of-synbiotic-administration-through-in-ovo-technology-on-the-microstructure-of-a-broiler-chicken-small-intestine-tissue-on-the-1-st-and-42-nd-day-of-rearing
#5
A Sobolewska, J Bogucka, A Dankowiakowska, G Elminowska-Wenda, K Stadnicka, M Bednarczyk
BACKGROUND: Application the innovative method which is in ovo technology provides a means of modulating the immune system at early embryonic stages. The aim of study was to determine influence of the in ovo stimulation, on d 12 of incubation, with synbiotics (synbiotic 1- L. salivarius IBB3154 + Bi(2)tos, Clasado Ltd. and the synbiotic 2 - L. plantarum IBB3036 + lupin RFOs) on the microstructure of duodenum, jejunum and ileum in the 1(st) and 42(nd) day of rearing. RESULTS: On the 1(st) day of chickens life, in the duodenum of both experimental groups (SYN1 and SYN2), a significantly higher and wider intestinal villi as well as a significantly larger absorbent surface of these villi were found in comparison with the Control group (P ≤ 0...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28777781/total-oxidant-antioxidant-status-in-sera-of-patients-with-esophageal-cancer
#6
Qingmei Huang, Jiafu Feng, Rong Wu, Yuwei Yang, Chunmei Dai, Jie Li, Yao Liao, Miao Xiang, Dong Wang, Xiao-Bo Du
BACKGROUND Oxidative stress parameters such as total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) have been studied in breast, thyroid, and simple esophageal cancers (EC). We evaluated these parameters in patients with EC and analyzed their correlations with treatment outcomes. MATERIAL AND METHODS Serum TOS, TAS, and OSI in 92 patients with EC at different clinical stages and in 64 healthy people (controls) were measured. RESULTS Serum TOS, TAS, and OSI were significantly different between patients with EC and healthy controls (all p<0...
August 4, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28760704/determination-of-alpha-2-mrap-gene-polymorphisms-in-nephrolithiasis-patients
#7
Atheer Awad Mehde, Wesen Adel Mehdi, Faridah Yusof, Raha Ahmed Raus, Zaima Azira Zainal Abidin, Hamid Ghazali, Azlina Abd Rahman
BACKGROUND: The intron 5 insertion/deletion polymorphism of Alpha-2-macroglobulin receptor-associated protein gene (Alpha-2-MRAP) has been implicated in numerous diseases. The current study was designed to analyze the association of intron 5 insertion/deletion polymorphism of Alpha-2-MRAP with nephrolithiasis patients. METHODS: PCR was conducted on genomic DNA of patients and control to look for Alpha-2-MRAP insertion/deletion polymorphism. Besides that, serum level of Alpha-2-MRAP, oxidative stress marker myeloperoxidase, Malondialdehyde (MDA), Advanced oxidation protein products (AOPP), and uric acid were determined...
July 29, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28750026/differences-in-biopsychosocial-profiles-of-diabetes-patients-by-level-of-glycaemic-control-and-health-related-quality-of-life-the-maastricht-study
#8
Arianne M J Elissen, Dorijn F L Hertroijs, Nicolaas C Schaper, Hans Bosma, Pieter C Dagnelie, Ronald M Henry, Carla J van der Kallen, Annemarie Koster, Miranda T Schram, Coen D A Stehouwer, Johannes S A G Schouten, Tos T J M Berendschot, Dirk Ruwaard
AIMS: Tailored, patient-centred innovations are needed in the care for persons with type 2 diabetes mellitus (T2DM), in particular those with insufficient glycaemic control. Therefore, this study sought to assess their biopsychosocial characteristics and explore whether distinct biopsychosocial profiles exist within this subpopulation, which differ in health-related quality of life (HRQoL). METHODS: Cross-sectional study based on data from The Maastricht Study, a population-based cohort study focused on the aetiology, pathophysiology, complications, and comorbidities of T2DM...
2017: PloS One
https://www.readbyqxmd.com/read/28745404/testicular-oocytes-in-smallmouth-bass-in-northeastern-minnesota-in-relation-to-varying-levels-of-human-activity
#9
Sarah M Kadlec, Rodney D Johnson, David R Mount, Jennifer H Olker, Brian D Borkholder, Patrick K Schoff
Testicular oocytes (TOs) have been found in black basses (Micropterus spp.) from many locations in North America. The presence of TOs is often assumed to imply exposure to estrogenic endocrine disrupting compounds (EDCs), however, a definitive causal relationship has yet to be established, and TO prevalence is not consistently low in fish from areas lacking evident EDC sources. This might indicate any of a number of situations: (a) unknown or unidentified EDCs or EDC sources, (b) induction of TOs by other stressors, or (c) TOs occurring spontaneously during normal development...
July 26, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28732612/image-guided-system-versus-manual-marking-for-toric-intraocular-lens-alignment-in-cataract-surgery
#10
Valentijn S C Webers, Noel J C Bauer, Nienke Visser, Tos T J M Berendschot, Frank J H M van den Biggelaar, Rudy M M A Nuijts
PURPOSE: To compare the accuracy of toric intraocular lens (IOL) alignment using the Verion Image-Guided System versus a conventional manual ink-marking procedure. SETTING: University Eye Clinic Maastricht, Maastricht, the Netherlands. DESIGN: Prospective randomized clinical trial. METHODS: Eyes with regular corneal astigmatism of at least 1.25 diopters (D) that required cataract surgery and toric IOL implantation (Acrysof SN6AT3-T9) were randomly assigned to the image-guided group or the manual-marking group...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28727368/medical-ozone-therapy-reduces-oxidative-stress-and-testicular-damage-in-an-experimental-model-of-testicular-torsion-in-rats
#11
Mustafa Tusat, Ahmet Mentese, Selim Demir, Ahmet Alver, Mustafa Imamoglu
OBJECTIVE: Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate the effect of ozone therapy on testicular damage due to I/R injury in an experimental torsion model. MATERIALS AND METHODS: 24 male Sprague-Dawley rats were divided into 3 groups; sham-operated, torsion/detorsion (T/D), and T/D+ozone...
June 14, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28721011/effect-of-picroside-ii-on-hind-limb-ischemia-reperfusion-injury-in-rats
#12
Yiğit Kılıç, Abdullah Özer, Tolga Tatar, Mustafa Hakan Zor, Mehmet Kirişçi, Hakan Kartal, Ali Doğan Dursun, Deniz Billur, Mustafa Arslan, Ayşegül Küçük
INTRODUCTION: Many structural and functional damages are observed in cells and tissues after reperfusion of previously viable ischemic tissues. Acute ischemia reperfusion (I/R) injury of lower extremities occurs especially when a temporary cross-clamp is applied to the abdominal aorta during aortic surgery. Research regarding the treatment of I/R injury has been increasing day-by-day. In this study, we aimed to investigate the effect of picroside II on skeletal muscle of rats experiencing simulated I/R...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28720348/safety-evaluation-of-a-novel-muramidase-for-feed-application
#13
J Lichtenberg, E Perez Calvo, K Madsen, T Østergaard Lund, F Kramer Birkved, S van Cauwenberghe, M Mourier, L Wulf-Andersen, A J M Jansman, R Lopez-Ulibarri
Safety evaluation of a muramidase produced by a Trichoderma reesei strain (safe lineage), expressing a muramidase gene isolated from Acremonium alcalophilum is presented. Intended use in feed of this enzyme is as digestive aid in broiler chickens. Muramidase 007, was non-mutagenic and non-clastogenic in vitro, and no adverse effects were observed in 90-day subchronic toxicity studies in rats at doses up to 1132 mg TOS/kg body weight/day. The enzyme did not exhibit, in vitro, skin, nor eye irritation potential...
July 15, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28711023/gingival-crevicular-fluid-and-plasma-oxidative-stress-markers-and-tgm-2-levels-in-chronic-periodontitis
#14
Sema Becerik, Veli Özgen Öztürk, Peter Celec, Natalia Kamodyova, Gül Atilla, Gülnur Emingil
OBJECTIVE: This study was aimed to evaluate the gingival crevicular fluid (GCF) and plasma transglutaminase-2 (TGM-2), total antioxidant capacity (TAC), total oxidant status (TOS), ferric reducing antioxidant power (FRAP) and thiobarbituric acid reactive substances (TBARS) in patients with chronic periodontal disease. MATERIALS AND METHODS: Twenty patients with chronic periodontitis (CP), 20 patients with gingivitis and 20 healthy subjects were enrolled in the study...
June 29, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28707148/chemokine-c-c-motif-ligand-2-ccl2-and-oxidative-stress-markers-in-recurrent-pregnancy-loss-and-repeated-implantation-failure
#15
Müberra Namlı Kalem, Nilufer Akgun, Ziya Kalem, Batuhan Bakirarar, Tugrul Celik
PURPOSE: The main purpose of this study is to evaluate the inflammatory response and oxidative stress together in the cases of recurrent pregnancy loss (RPL) and repeated implantation failure (RIF). METHODS: This is a cross-sectional study conducted to compare infertile patients who have RIF and patients with RPL histories in terms of CCL2, TAS, TOS, and OSI. To this end, two study groups were formed by primary-infertile women with RIF history and women with nulliparous RPL history who consulted a university hospital between 2014 and 2016, and a control group was formed by multiparous women who had no pregnancy loss...
July 13, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28706577/risperidone-induced-renal-damage-and-metabolic-side-effects-the-protective-effect-of-resveratrol
#16
Sedat Bilgiç, Deniz Taştemir Korkmaz, Sebile Azirak, Ayşe Nilay Güvenç, Nevin Kocaman, Mehmet Kaya Özer
OBJECTIVE: The aim of the study was to investigate the possible protective qualities of resveratrol (RSV) against the side effects of risperidone (RIS) in an experimental model in rat kidneys with histologic and biochemical assessments. MATERIALS AND METHODS: Experimental procedures were performed on 35 female Sprague Dawley rats. Rats were randomly divided into five groups: control, untreated rats (n = 7) were in group 1; group 2 was given 2 mg/kg/day RIS (n = 7); group 3 was treated with 2 mg/kg/day RIS and 20 mg/kg/day RSV (n = 7); group 4 was treated with 2 mg/kg/day RIS and 40 mg/kg/day RSV (n = 7); and group 5 was treated with 2 mg/kg/day RIS and 80 mg/kg/day RSV (n = 7)...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28704751/protective-effect-of-ferulic-acid-on-cisplatin-induced-nephrotoxicity-in-rats
#17
Erliasa Bami, Ozlem Bingol Ozakpınar, Zarife Nigar Ozdemir-Kumral, Kutay Köroglu, Feriha Ercan, Zeynep Cirakli, Turgut Sekerler, Fikret Vehbi Izzettin, Mesut Sancar, Betul Okuyan
This study aims to determine the potential protective effects of ferulic acid against cisplatin-induced nephrotoxicity and to compare its effect with curcumin, a well-known protective agent against cisplatin- induced toxicity in rats. Administration of cisplatin resulted in high BUN (Blood Urea Nitrogen), creatinine, MDA (Malondialdehyde), MPO (Myeloperoxidase), TOS (Total Oxidative Status), PtNT (Protein Nitrotyrosine) levels (p<0.05). Histological observations showed abnormal morphology of kidney; in addition with appearance of TUNEL positive cells indicating apoptosis in cisplatin administered group...
July 1, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28693145/association-between-chromosomal-aberration-of-exfoliated-bladder-cells-in-the-urine-and-oxidative-stress-in-patients-with-bladder-transitional-cell-carcinoma
#18
Dong Wang, Jia-Fu Feng, Guang-Ya Yuan, Yong-Hong Yang, Yun-Shuang Liu, Yu-Wei Yang
The aim of the current study was to investigate the chromosomal aberrations of exfoliated bladder cells in the urine and blood oxidative stress in patients with bladder transitional cell carcinoma (BTCC). A total of 40 healthy controls and 246 patients with BTCC were recruited. Abnormal levels of CSP3, CSP7, CSP17 and GLPp16 were detected by fluorescence in situ hybridization (FISH) in exfoliated bladder cells in the urine of patients with BTCC. Serum total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) were measured...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28680345/oxidative-stress-and-antioxidant-status-in-patients-with-bell-s-palsy
#19
Suat Terzi, Engin Dursun, Adnan Yılmaz, Zerrin Özergin Coşkun, Abdulkadir Özgür, Metin Çeliker, Münir Demirci
BACKGROUND: Bell's palsy (BP) is the most common acute mononeuropathy of unilateral facial paralysis. Immune, infective and ischaemic mechanisms are potential contributors to the development of BP, but the precise cause remains unclear. Recently, oxidative stress has been proposed as a risk factor of various idiopathic diseases. The aim of this study was to investigate the possible role of oxidative stress in patients with BP. METHODS: Thirty-two patients with BP and 30 healthy controls were included in this study...
January 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28677632/ultrasonographic-diagnosis-of-thoracic-outlet-syndrome-secondary-to-brachial-plexus-piercing-variation
#20
Vanessa Leonhard, Gregory Caldwell, Mei Goh, Sean Reeder, Heather F Smith
Structural variations of the thoracic outlet create a unique risk for neurogenic thoracic outlet syndrome (nTOS) that is difficult to diagnose clinically. Common anatomical variations in brachial plexus (BP) branching were recently discovered in which portions of the proximal plexus pierce the anterior scalene. This results in possible impingement of BP nerves within the muscle belly and, therefore, predisposition for nTOS. We hypothesized that some cases of disputed nTOS result from these BP branching variants...
July 4, 2017: Diagnostics
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