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Periodontics Treatment

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https://www.readbyqxmd.com/read/29342179/the-polymethoxy-flavonoid-sudachitin-suppresses-inflammatory-bone-destruction-by-directly-inhibiting-osteoclastogenesis-due-to-reduced-ros-production-and-mapk-activation-in-osteoclast-precursors
#1
Yoko Ohyama, Junta Ito, Victor J Kitano, Jun Shimada, Yoshiyuki Hakeda
Inflammatory bone diseases, including rheumatoid arthritis, periodontitis and peri-implantitis, are associated not only with the production of inflammatory cytokines but also with local oxidative status, which is defined by intracellular reactive oxygen species (ROS). Osteoclast differentiation has been reported to be related to increased intracellular ROS levels in osteoclast lineage cells. Sudachitin, which is a polymethoxyflavone derived from Citrus sudachi, possesses antioxidant properties and regulates various functions in mammalian cells...
2018: PloS One
https://www.readbyqxmd.com/read/29341486/rheumatoid-arthritis-and-periodontal-disease-what-are-the-similarities-and-differences
#2
REVIEW
Rongbin Li, Cheng Tian, Arnold Postlethwaite, Yan Jiao, Franklin Garcia-Godoy, Debendra Pattanaik, Dongmei Wei, Weikuan Gu, Jianwei Li
Rheumatoid arthritis (RA) and periodontal disease (PD) are chronic inflammatory diseases that share similar osteoclasia, human leukocyte antigen-DR4 allelic genes and immunological profile, and characteristic cytokines. Smoking can contribute to more severe RA and PD; secretion of pro-inflammatory mediators destroys the soft synovial membrane and periodontium, respectively. Anti-citrullinated protein antibodies and anti-α-enolase antibody are characteristic of these two diseases. Some studies suggest that PD may be associated with RA...
December 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29339824/oral-microbiota-of-periodontal-health-and-disease-and-their-changes-after-nonsurgical-periodontal-therapy
#3
Casey Chen, Chris Hemme, Joan Beleno, Zhou Jason Shi, Daliang Ning, Yujia Qin, Qichao Tu, Michael Jorgensen, Zhili He, Liyou Wu, Jizhong Zhou
This study examined the microbial diversity and community assembly of oral microbiota in periodontal health and disease and after nonsurgical periodontal treatment. The V4 region of 16S rRNA gene from DNA of 238 saliva and subgingival samples of 21 healthy and 48 diseased subjects was amplified and sequenced. Among 1979 OTUs identified, 28 were overabundant in diseased plaque. Six of these taxa were also overabundant in diseased saliva. Twelve OTUs were overabundant in healthy plaque. There was a trend for disease-associated taxa to decrease and health-associated taxa to increase after treatment with notable variations among individual sites...
January 16, 2018: ISME Journal
https://www.readbyqxmd.com/read/29338161/effect-of-periodontal-treatment-on-the-crevicular-level-of-high-mobility-group-box-1-and-soluble-triggering-receptor-expressed-on-myeloid-cells-1-in-patients-with-chronic-periodontitis
#4
Mojgan Paknejad, Mandana Sattari, Solmaz Akbari, Ali Mehrfard, Hoori Aslroosta
The present study aimed to compare the levels of high-mobility group box 1(HMGB1) and soluble triggering receptor expressed on myeloid cells (sTREM1) in the gingival crevicular fluid (GCF). This cross-sectional cohort trial investigated two groups of 22 eligible chronic periodontitis and 22 periodontally healthy individuals (student volunteers) both before and after the periodontal treatment.  GCF was collected from the deepest pockets with clinical attachment loss≥3 mm. Both groups received oral hygiene instructions, and scaling and root planning were performed in the test group...
December 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29337645/conservative-approach-for-treatment-of-maxillary-lateral-incisor-agenesis-with-the-deciduous-tooth-retained-18-month-follow-up
#5
Cecm Lameira, S R Mestrener, Nip Pini, F M Salomão, A A Pesqueira, T C Fagundes
This case describes a female patient with agenesis of the maxillary right lateral incisor, with her permanent canine in its position and the deciduous canine retained. Additionally, she presented with a maxillary left peg lateral incisor. To solve her functional and esthetic complaints, a multidisciplinary approach involving perio-restorative procedures was proposed. Periodontal surgeries were performed to align the gingival contour, and the restorative approach utilized ceramic veneers. At the 18-month clinical and radiographic follow-up, the treatment outcome was stable, with maintenance of the clinical results achieved and without any sign of deciduous tooth resorption...
January 16, 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29336261/formulation-and-investigation-of-a-lipid-based-delivery-system-containing-antimicrobials-for-the-treatment-of-periodontal-disease
#6
Attila Leber, Maria Budai-Szucs, Edit Urban, Peter Valyi, Anita Kovacs, Szilvia Berko, Erzsebet Csanyi
BACKGROUND: Periodontitis is a chronic inflammatory disease, which affects the supporting tissues of the teeth, and without proper treatment it may lead to tooth loss. Antibiotics - dministered orally - have been widely used in the treatment of periodontitis. With the conventional administration routes, adequate drug levels cannot be reached in the periodontal pockets and oral application of antimicrobials could lead to side effects. Drug delivery systems containing antibiotics, administered at the site of infection, could possibly help eliminate pathogen bacteria and treat periodontitis...
January 15, 2018: Current Drug Delivery
https://www.readbyqxmd.com/read/29334297/perceptions-of-older-people-s-oral-health-care-among-nurses-working-in-geriatric-home-care
#7
Taru Aro, Marjo Laitala, Anna-Maija Syrjälä, Marja-Liisa Laitala, Jorma I Virtanen
OBJECTIVES: This study investigates nurses' self-reported experiences and perceptions of older people's oral health care using a qualitative method. METHODS: We interviewed 10 nurses working in geriatric home care who regularly visit and take care of older people in their homes. The interviews consisted of semi-structured questions. The interviews were then transcribed and analysed. RESULTS: All nurses were aware of the connection between oral health and general health, but more detailed knowledge about oral health was lacking and confidence in oral health care practices was limited...
January 15, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29333779/-decalcified-freeze-dried-bone-allograft-combined-with-rich-platelet-derivatives-for-the-treatment-of-human-periodontal-intrabony-defects-a-meta-analysis
#8
Wei Xue, Zhong Xiaobo, He Bin, Deng Yanhan, Luo Shumei
OBJECTIVE: This review aims to systematically evaluate the effect of decalcified freeze-dried bone allograft (DFDBA) combined with rich platelet derivatives on the treatment of human periodontal intrabony defects. METHODS: A search in PubMed, Web of Science, Embase, Cochrane Library, CNKI, and other electronic databases was conducted to identify randomized controlled trials (RCT) of the use of DFDBA combined with rich platelet derivatives in the treatment of human periodontal intrabony defects, performed before May 2016...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29333776/-clinical-and-microbiologic-follow-up-evaluations-after-non-surgical-periodontal-treatment-with-nd-yag-laser-and-scaling-and-root-planning
#9
Yin Yanli, Xu Chunmei, Wu Yafei, Zhao Lei
OBJECTIVE: Our research aimed to detect the efficacy of non-surgical periodontal treatment with Nd: YAG laser and scaling and root planning (SRP) for chronic periodontitis. METHODS: We recruited chronic periodontitis patients who have more than four teeth with clinical pocket depth of 4-8 mm. These teeth were distributed in four different zones within the oral cavity. Moreover, the teeth were single root teeth and not adjacent to each other. The subordinated teeth were randomized into four groups, as follows: no treatment (C group), simple SRP (SRP group), Nd: YAG laser after SRP treatment (SRP+L group), and SRP after Nd: YAG laser treatment (L+SRP group)...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29333321/periodontal-wound-healing-following-reciprocal-autologous-root-transplantation-in-class-iii-furcation-defects
#10
Naoshi Takeuchi, Yoshinori Shirakata, Yukiya Shinohara, Kotaro Sena, Kazuyuki Noguchi
Purpose: Furcation involvement in the molars is difficult to treat, and has been recognized as a risk factor for tooth loss. Although periodontal regenerative therapies, including guided tissue regeneration and various types of bone grafts, have been applied to furcation defects, the effects of these treatments are limited, especially in large class III furcation defects. The purpose of this pilot study was to investigate the effect of reciprocal autologous root transplantation on periodontal wound healing and regeneration in class III furcation defects in dogs...
December 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29332208/localised-aggressive-periodontitis-in-a-3-year-old-boy
#11
E Mass, F Hershkovitz, U Zilberman
BACKGROUND: Localised aggressive periodontitis (LAgP), characterised by rapid attachment and bone loss, which may occur in children and adolescents, without clinical evidence of systemic disease. CASE REPORT: Three-year-old boy was referred with excessive mobility of 83 and exfoliation of 73. Clinical examination revealed acceptable oral hygiene. Blood tests were performed to evaluate PMNs activity and the parents were advised to apply 0.2% chlorhexidine twice a day...
January 13, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29331511/maresin-1-regulates-autophagy-and-inflammation-in-human-periodontal-ligament-cells-through-glycogen-synthase-kinase-3%C3%AE-%C3%AE-catenin-pathway-under-inflammatory-conditions
#12
Li Du, Yucheng Li, Weifeng Liu
OBJECTIVE: Accumulating lines of evidence suggest that maresin 1 (MaR-1) exerts anti-inflammatory effects in many cell types and plays beneficial roles in inflammatory disease, such as peritonitis and colitis. Moreover, it has been demonstrated that MaR-1 play protective roles against localized aggressive periodontitis. However, the function and mechanism of MaR-1 in human periodontal ligament cells (PDL) cells from periodontitis are poorly understood. The present study aimed to clarify the effects and molecular mechanism of MaR-1 in PDL cell survival and inflammation...
December 23, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29330841/delayed-replantation-of-an-avulsed-immature-permanent-incisor-and-apexification-using-a-novel-fast-setting-calcium-silicate-cement-containing-fluoride-a-3-year-follow-up-case-report
#13
A Vafaei, B Ranjkesh, L Erfanparast, H Løvschall
BACKGROUND: Traumatic tooth avulsion requires an urgent intervention to replant the tooth. Prolonged post-injury dry extra-oral conditions worsen the prognosis and increase the risk of root resorption. Fluoride has the potential to delay replacement resorption. Calcium silicate cements (CSC) are used to seal the root canal system and to stimulate periapical regeneration in immature open apex teeth (apexification). This report suggests the application of a novel fast-setting CSC with fluoride for apexification in an attempt to hinder root resorption...
January 12, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29330707/effects-of-periodontal-treatment-on-carotid-intima-media-thickness-in-patients-with-lifestyle-related-diseases-japanese-prospective-multicentre-observational-study
#14
Chieko Kudo, Wee Soo Shin, Nobuhiro Sasaki, Kazuo Harai, Kai Kato, Hiroaki Seino, Eiji Goke, Takemasa Fujino, Nobuichi Kuribayashi, Youko Onuki Pearce, Masato Taira, Ryoji Matsushima, Masato Minabe, Shogo Takashiba
Atherosclerosis, a chronic inflammatory disease in arterial blood vessels, is one of the major causes of death in worldwide. Meanwhile, periodontal disease is a chronic inflammatory disease caused by infection with periodontal pathogens such as P. gingivalis (Porphyromonas gingivalis). Several studies have reported association between periodontal infection and atherosclerosis, but direct investigation about the effects of periodontal treatment on atherosclerosis has not been reported. We have planned Japanese local clinics to determine the relationship between periodontal disease and atherosclerosis under collaborative with medical and dental care...
January 12, 2018: Odontology
https://www.readbyqxmd.com/read/29330656/3d-imaging-3d-printing-and-3d-virtual-planning-in-endodontics
#15
REVIEW
Pratik Shah, B S Chong
The adoption and adaptation of recent advances in digital technology, such as three-dimensional (3D) printed objects and haptic simulators, in dentistry have influenced teaching and/or management of cases involving implant, craniofacial, maxillofacial, orthognathic and periodontal treatments. 3D printed models and guides may help operators plan and tackle complicated non-surgical and surgical endodontic treatment and may aid skill acquisition. Haptic simulators may assist in the development of competency in endodontic procedures through the acquisition of psycho-motor skills...
January 12, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29329335/immunization-with-gingipain-a-hemagglutinin-domain-of-porphyromonas-gingivalis-induces-igm-antibodies-binding-to-malondialdehyde-acetaldehyde-modified-low-density-lipoprotein
#16
Mikael Kyrklund, Outi Kummu, Jari Kankaanpää, Ramin Akhi, Antti Nissinen, S Pauliina Turunen, Pirkko Pussinen, Chunguang Wang, Sohvi Hörkkö
Treatment of periodontitis has beneficial effects on systemic inflammation markers that relate to progression of atherosclerosis. We aimed to investigate whether immunization with A hemagglutinin domain (Rgp44) of Porphyromonas gingivalis (Pg), a major etiologic agent of periodontitis, would lead to an antibody response cross-reacting with oxidized low-density lipoprotein (OxLDL) and how it would affect the progression of atherosclerosis in low-density lipoprotein receptor-deficient (LDLR-/-) mice. The data revealed a prominent IgM but not IgG response to malondialdehyde-acetaldehyde modified LDL (MAA-LDL) after Rgp44 and Pg immunizations, implying that Rgp44/Pg and MAA adducts may share cross-reactive epitopes that prompt IgM antibody production and consequently confer atheroprotection...
2018: PloS One
https://www.readbyqxmd.com/read/29327449/clinical-microbiological-and-cytomorphometric-evaluation-of-low-level-laser-therapy-as-an-adjunct-to-periodontal-therapy-in-patients-with-chronic-periodontitis
#17
M S Petrović, I Y Kannosh, J M Milašin, D S Mihailović, R R Obradović, S R Bubanj, L G Kesić
OBJECTIVE: A clinical prospective study was designed to evaluate microbiological, cytomorphometric and clinical efficacy of low-level laser therapy (LLLT) as an adjunct to periodontal therapy in the treatment of chronic periodontitis. METHODS: Sixty subjects were included and randomly assigned into 2 groups: SRP (scaling root planning) group (n = 30) and LLLT + SRP group (n = 30). Clinical parameters were measured before intervention, after the fifth treatment, and after a month...
January 12, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29327269/unfair-treatment-and-periodontitis-among-adults-in-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#18
Tracy L Finlayson, Hector Lemus, Karen Becerra, Linda M Kaste, Shirley M Beaver, Christian R Salazar, Richard H Singer, Marston E Youngblood
This study investigates how perceived unfair treatment, towards self and observed towards others due to ethnicity, is associated with periodontitis among diverse Hispanic/Latino adults, accounting for sociodemographic, health behavior, and acculturation factors. Baseline (2008-2011) dental and survey data from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a multicenter epidemiologic study, were analyzed (N = 12,750). Crude and adjusted prevalence ratios and confidence limits were estimated...
January 11, 2018: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29326507/effect-of-calcium-channel-blockers-on-gingival-tissues-in-hypertensive-patients-in-lagos-nigeria-a-pilot-study
#19
Kehinde Adesola Umeizudike, Adetokunbo B Olawuyi, Theophilus I Umeizudike, Akinsanya D Olusegun-Joseph, Babawale T Bello
Background: Long-term treatment of common chronic cardiac conditions such as hypertension with calcium channel blockers (CCBs) has long been associated with gingival hyperplasia. This oral side effect may affect esthetics and function, yet often overlooked and therefore underreported among Nigerians. Aim: This study aimed to determine the association of CCBs with gingival overgrowth (GO) in hypertensive patients. Methods: This was a hospital-based, case-control study conducted among 116 hypertensive patients (58 CCB and 58 non-CCB age-matched controls) attending the medical outpatient clinic of a tertiary health institution in Lagos, Nigeria...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29326502/comparative-evaluation-of-platelet-rich-fibrin-with-connective-tissue-grafts-in-the-treatment-of-miller-s-class-i-gingival-recessions
#20
Sonam Mufti, Sarvagna Mayank Dadawala, Phoram Patel, Monali Shah, Deepak Harish Dave
Background: One of the most common aesthetic problem encountered in the field of periodontology is gingival recession, which is, perceived by the patients as increase in length of teeth. The treatment of buccal gingival recession is a common requirement due to aesthetic concern or root sensitivity. This study was planned to evaluate the efficacy of PRF membrane compared to that of CTG in Miller's class I gingival recessions. Materials and Methods: 32 sites with Miller's Class I gingival recessions, out of which 16 sites received PRF (test) and 16 sites received CTG (control)...
October 2017: Contemporary Clinical Dentistry
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