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Periodontics Treatment

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https://www.readbyqxmd.com/read/28102013/the-effect-of-potassium-diclofenac-and-dexamethasone-on-mmp-1-gene-transcript-levels-during-experimental-tooth-movement-in-rats
#1
G P Molina Da Silva, O M Tanaka, D F Campos Navarro, C E Repeke, G P Garlet, O Guariza-Filho, P C Trevilatto
OBJECTIVES: The aim of this study was to analyze MMP-1 transcript levels in periodontal tissues of rats that underwent orthodontic treatment using potassium diclofenac and dexamethasone at different stages of tooth movement. SETTING AND SAMPLE POPULATION: The sample comprised of ninety male Wistar rats. MATERIAL AND METHODS: A closed nickel-titanium coil spring was used to apply a force of 50 cN to move the maxillary right first molars mesially...
February 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28099577/effects-of-periodontal-treatment-on-primary-sj%C3%A8-gren-s-syndrome-symptoms
#2
Lucas Macedo Batitucci Ambrósio, Emanuel da Silva Rovai, Bruno Nunes de França, Danilo Andrés Balzarini, Ieda Santos Abreu, Sheyla Batista Bologna Lopes, Thaís Borguezan Nunes, Silvia Vanessa Lourenço, Sandra Gofinet Pasoto, Luciana Saraiva, Marinella Holzhausen
The aim of this longitudinal prospective study was to evaluate the effects of periodontal treatment on the clinical, microbiological and immunological periodontal parameters, and on the systemic activity (ESSDAI) and subjective (ESSPRI) indexes in patients with primary Sjögren's Syndrome (pSS). Twenty-eight female patients were divided into four groups: pSS patients with or without chronic periodontitis (SCP, SC, respectively), and systemically healthy patients with or without chronic periodontitis (CP, C, respectively)...
January 16, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28098777/new-irradiation-method-with-indocyanine-green-loaded-nanospheres-for-inactivating-periodontal-pathogens
#3
Yasuyuki Sasaki, Jun-Ichiro Hayashi, Takeki Fujimura, Yuki Iwamura, Genta Yamamoto, Eisaku Nishida, Tasuku Ohno, Kosuke Okada, Hiromitsu Yamamoto, Takeshi Kikuchi, Akio Mitani, Mitsuo Fukuda
Antimicrobial photodynamic therapy (aPDT) has been proposed as an adjunctive strategy for periodontitis treatments. However, use of aPDT for periodontal treatment is complicated by the difficulty in accessing morphologically complex lesions such as furcation involvement, which the irradiation beam (which is targeted parallel to the tooth axis into the periodontal pocket) cannot access directly. The aim of this study was to validate a modified aPDT method that photosensitizes indocyanine green-loaded nanospheres through the gingivae from outside the pocket using a diode laser...
January 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28095518/long-term-results-of-peri-implant-conditions-in-periodontally-compromised-patients-following-lateral-bone-augmentation
#4
Philip L Keeve, Fouad Khoury
PURPOSE: The aim of this retrospective study was to compare long-term (≥ 5 years) outcomes of implants placed in patients treated for chronic periodontitis versus those placed in periodontally healthy patients. In both groups, the implants were placed in alveolar ridges that were laterally augmented with autogenous bone block grafts using a split bone block technique. MATERIALS AND METHODS: Two hundred ninety-two patients were screened in the course of supportive periodontal treatment examinations...
January 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28095260/differential-expression-and-roles-of-secreted-frizzled-related-protein-5-and-the-wingless-homolog-wnt5a-in-periodontitis
#5
T Maekawa, P Kulwattanaporn, K Hosur, H Domon, M Oda, Y Terao, T Maeda, G Hajishengallis
The Wingless/integrase-1 (Wnt) family of protein ligands and their functional antagonists, secreted frizzled-related proteins (sFRPs), regulate various biological processes ranging from embryonic development to immunity and inflammation. Wnt5a and sFRP5 comprise a typical ligand/antagonist pair, and the former molecule was recently detected at the messenger RNA (mRNA) level in human periodontitis. The main objective of this study was to investigate the interrelationship of expression of Wnt5a and sFRP5 in human periodontitis (as compared to health) and to determine their roles in inflammation and bone loss in an animal model...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28093319/anti-inflammatory-effect-of-the-salvia-sclarea-l-ethanolic-extract-on-lipopolysaccharide-induced-periodontitis-in-rats
#6
Milica Kostić, Dušanka Kitić, Milica B Petrović, Tatjana Jevtović-Stojmenov, Marko Jović, Aleksandar Petrović, Slavoljub Živanović
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia sclarea L., clary, is an aromatic plant traditionally used in folk medicine for the treatment of various diseases and conditions. Although it has been primarily used as a stomachic, there are data on traditional use of S. sclarea as an agent against gingivitis, stomatitis and aphthae. AIM OF THE STUDY: The aim of the study was to examine the effect of the S. sclarea ethanolic extract on the lipopolysaccharide (LPS)-induced periodontitis in rats from the immunological and histopathological standpoint...
January 13, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28091721/influence-of-tooth-dimension-on-the-initial-mobility-based-on-plaster-casts-and-x-ray-images-a-numerical-study
#7
Martin Hartmann, Cornelius Dirk, Susanne Reimann, Ludger Keilig, Anna Konermann, Andreas Jäger, Christoph Bourauel
AIMS: The goal was to determine the influence of different geometric parameters of the tooth on the initial tooth mobility and the position of the center of resistance employing numerical models based on scaled X-ray images and plaster casts. METHODS: The dimensions of tooth 21 were measured in 21 patients, using radiographs and dental casts. Length and mesiodistal width of the tooth were obtained from the X-ray image and the orovestibular diameter from the plaster cast...
January 13, 2017: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/28091448/oro-dental-characteristics-of-three-siblings-with-papillon-lefevre-syndrome
#8
O E Gungor, H Karayilmaz, H Yalcin, M Hatipoğlu
Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder, showing oral and dermatological manifestations in the form of aggressive periodontitis, leading to the premature loss of both primary and permanent teeth at a very young age and palmar-plantar hyperkeratosis. It was first described by two French physicians, Papillon and Lefevre in 1924. Immunologic, genetic, or possible bacterial etiologies have been thought to account for etiopathogenesis of PLS. Severe gingival inflammation and periodontal destruction occurred after the eruption of primary teeth...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28087575/treating-inflammation-and-infection-in-the-21st-century-new-hints-from-decoding-resolution-mediators-and-mechanisms
#9
REVIEW
Charles N Serhan
Practitioners of ancient societies from the time of Hippocrates and earlier recognized and treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or inhibit proinflammatory chemical mediators. More selective drugs are available today, but this therapeutic concept has not changed. Because the acute inflammatory response is host protective to contain foreign invaders, much of today's pharmacopeia can cause serious unwanted side effects, such as immune suppression. Uncontrolled inflammation is now considered pathophysiologic and is associated with many widely occurring diseases such as cardiovascular disease, neurodegenerative diseases, diabetes, obesity, and asthma, as well as classic inflammatory diseases (e...
January 13, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28081379/direct-gingival-fibroblast-osteoblast-transdifferentiation-via-epigenetics
#10
Y Cho, B Kim, H Bae, W Kim, J Baek, K Woo, G Lee, Y Seol, Y Lee, Y Ku, I Rhyu, H Ryoo
Alveolar bone resorption caused by trauma or periodontal diseases has represented a challenge for both dental clinicians and researchers. In this study, we evaluate the osteogenic potential of human gingival fibroblasts (HGFs) through a direct transdifferentiation from HGFs to functional osteoblasts via epigenetic modification and osteogenic signaling with bone morphogenetic protein 2 (BMP2) in vitro and in vivo. HGF treatment with 5-aza-2'-deoxycytidine (5-aza-dC) induced demethylation in the hypermethylated CpG islands of the osteogenic lineage marker genes RUNX2 and ALP, and subsequent BMP2 treatment successfully drove the fibroblasts to the osteoblasts' lineage...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28078880/orthodontic-forces-modulate-insulin-like-growth-factor-binding-protein-5-changes-in-gingival-crevicular-fluid
#11
A Ballini, L Santacroce, S Cantore, R Saini, F Mastrangelo, A Desiate, S Scacco
Orthodontic tooth movement results from the response of the periodontal tissue to orthodontic force, which leads to modeling and remodeling of the surrounding alveolar bone. The response is considered to occur through the activation of specific signaling pathways, many of which are known, all acting to ultimately result in tooth movement. Much is known about the actions of these two cells, and the signaling pathways that affect them, both in bone and orthodontic literature, however, to date, little work has been carried out to examine the effect of the insulin-like growth factor binding proteins (IGFBP) in orthodontics...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28078876/comparative-molecular-analysis-of-bacterial-species-associated-with-periodontal-disease
#12
V De Iuliis, S Ursi, L M Di Tommaso, M Caruso, A Marino, S D Ercole, S Caputi, B Sinjari, F Festa, M Macri, S Martinotti, G Vitullo, E Toniato
Periodontal disease is an inflammatory disorder affecting the supporting teeth structures, including gingiva, periodontal ligament and alveolar bone, causing loss of connective tissue, reabsorption of alveolar bone and formation of periodontal pockets. The aim of this study is to find a correlation between bacterial growth and periodontal disease. Fifty-seven patients aged between 21 and 65 years, median age 46 years, were enrolled. According to gingival pocket depth, ranging from 3 to 7 mm, patients were divided into two groups: the first (30 patients, 53%) with deep pockets ³ 5 mm and the second (27 patients, 47%) less than 5 mm...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28068276/repositioning-of-a-pathologically-migrated-tooth-using-autologous-platelet-rich-plasma-a-case-report-with-3-year-follow-up
#13
B V Karthikeyan, Divya Khanna, M Lv Prabhuji
An intricate balance between the periodontal tissues and the forces of occlusion, tongue, and lips helps to maintain a tooth in its physiologic position within the dental arch. Disturbances in the equilibrium can cause a tooth to migrate pathologically, often requiring multidisciplinary treatment approaches. The present case demonstrates, for the first time, the use of autologous platelet-rich plasma to aid in tooth repositioning after pathologic tooth migration. A 25-year-old woman presented with extrusion and labial migration of the maxillary left central incisor, a diastema of 3 mm, and grade II mobility...
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28068274/dental-care-in-patients-with-antiphospholipid-syndrome-two-case-reports
#14
Karine Cestaro Mesquita, Carolina Rodrigues Teófilo, João Paulo Veloso Perdigão, Fabrício Bitu Sousa, Ana Paula Negreiros Nunes Alves, Wagner Araújo de Negreiros, Mário Rogério Lima Mota
Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disease that may be classified as primary or secondary. Treatment consists of oral anticoagulant, antiplatelet, and/or immunosuppressant drugs. This report describes the dental treatment of 2 women with APS and multiple dental concerns, including periodontal disease, caries, and missing teeth. The invasive dental procedures were performed in an outpatient setting with hematologic monitoring and use of local hemostatic measures. Neither interruption of anticoagulant medications nor administration of blood products was necessary...
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28068273/novel-use-of-calcium-phosphosilicate-synthetic-graft-material-for-treatment-of-a-palatoradicular-groove-associated-with-an-osseous-defect-a-case-report
#15
M Lv Prabhuji, Rishi Dhamija, Shaeesta B Khaleelahmed
Palatoradicular grooves (PRGs), morphologic defects that are found most frequently in maxillary anterior teeth, are predisposing factors for periodontal disease. This case report describes the successful management of a 30-year-old man who presented with advanced periodontal destruction associated with a PRG in the maxillary right lateral incisor. The treatment involved the use of a calcium phosphosilicate synthetic bone graft substitute as a periodontal regenerative material.
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28066875/evaluating-the-effects-of-consolidation-on-intrusion-and-retraction-using-temporary-anchorage-devices-a-fem-study
#16
Monica Namburi, Sleevaraju Nagothu, Chetan S Kumar, N Chakrapani, C H Hanumantharao, Supradeep K Kumar
BACKGROUND: Extraction of premolars and retracting the anterior teeth using mini-implants and anterior retraction hooks became advent now a day. In such treatments, consolidation of arches is not done in regular practice. So, the present study is concentrated on effects of consolidation in two implant and three implant combinations of retraction and intrusion. METHODS: A three-dimensional FEM model of maxillary teeth and periodontal ligament housed in the alveolar bone with the first premolars extracted is generated with appropriate number of elements and nodes...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28063227/lipus-suppressed-lps-induced-il-1%C3%AE-through-the-inhibition-of-nf-%C3%AE%C2%BAb-nuclear-translocation-via-at1-plc%C3%AE-pathway-in-mc3t3-e1
#17
Mayu Nagao, Natsuko Tanabe, Soichiro Manaka, Masako Naito, Kumiko Nakai, Tadahiro Takayama, Takayuki Kawato, Go Torigoe, Jumpei Sekino, Naoya Tsukune, Masao Maeno, Naoto Suzuki, Shuichi Sato
Inflammatory cytokines, interleukin (IL)-1, IL-6, and TNF-a, are involved in inflammatory bone diseases such as rheumatoid osteoarthritis and periodontal disease. Particularly, periodontal disease, which destroys alveolar bone, is stimulated by lipopolysaccharide (LPS). Low-intensity pulsed ultrasound (LIPUS) is used for bone healing in orthopedics and dental treatments. However,the mechanism underlying effects of LIPUS on LPS-induced inflammatory cytokine are not well understood. We therefore aimed to investigate the role of LIPUS on LPS-induced IL-1a production...
January 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28061389/in-vitro-proliferation-of-periodontal-ligament-like-tissue-on-extracted-teeth
#18
T Iwata, C Mino, T Kawata
OBJECTIVE: Transplantation of autologous teeth is a routine component of orthodontic treatment. The aim of this study was to develop a method for the regeneration of damaged periodontal ligament (PDL) on extracted teeth using a three-dimensional culture system. DESIGN: We used the maxillary first premolars or third molars extracted from patients for orthodontic treatment. The extracted teeth were stained with toluidine blue to measure the residual PDL area. After confirming damage of the periodontal tissue on the root surface of the extracted teeth, we tried to regenerate the periodontal tissue...
November 30, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/28060561/aspirin-blocks-orthodontic-relapse-via-inhibition-of-cd4-t-lymphocytes
#19
Y Liu, T Zhang, C Zhang, S S Jin, R L Yang, X D Wang, N Jiang, Y H Gan, X X Kou, Y H Zhou
Immunologic response plays an important role in orthodontic tooth movement (OTM) and relapse. Nonsteroidal anti-inflammatory drugs, such as aspirin, affect immune cells and clinical orthodontic treatment. However, the mechanisms by which nonsteroidal anti-inflammatory drugs regulate immune cells to affect orthodontic relapse are unclear. In this study, male Sprague-Dawley rats were grouped as relapse and relapse + aspirin for 10 d after 14 d of OTM. Silicone impressions of the rats' maxillary dentitions were obtained to record the distance of OTM at the indicated time point...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28054789/corticotomy-accelerated-orthodontics-a-comprehensive-review-and-update
#20
Nouf Zimmo, Muhammad H A Saleh, George A Mandelaris, Hsun-Liang Chan, Hom-Lay Wang
Of all the modalities reported to decrease orthodontic treatment time, corticotomy-accelerated orthodontics (CAO) is the only evidence-based approach. The aim of this article is to critically review the available evidence and to summarize the pros and cons of CAO. Articles published in the last 15 years related to CAO were screened and critically assessed. Based on the literature, CAO results in acceleration of the orthodontic treatment rate as much as three times on average, in addition to many benefits not commonly recognized by the profession or reported in the literature...
January 2017: Compendium of Continuing Education in Dentistry
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