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https://www.readbyqxmd.com/read/28210286/bilastine-in-allergic-rhinoconjunctivitis-and-urticaria-a-practical-approach-to-treatment-decisions-based-on-queries-received-by-the-medical-information-department
#1
REVIEW
Amalia Leceta, Ander Sologuren, Román Valiente, Cristina Campo, Luis Labeaga
BACKGROUND: Bilastine is a safe and effective commonly prescribed non-sedating H1-antihistamine approved for symptomatic treatment in patients with allergic disorders such as rhinoconjunctivitis and urticaria. It was evaluated in many patients throughout the clinical development required for its approval, but clinical trials generally exclude many patients who will benefit in everyday clinical practice (especially those with coexisting diseases and/or being treated with concomitant drugs)...
2017: Drugs in Context
https://www.readbyqxmd.com/read/28208999/experience-from-classroom-teaching-to-clinical-practice-regarding-shortened-dental-arch-sda-concept-among-dentists-a-questionnaire-study
#2
Ritu Gupta, Ravneet Malhi, Basavaraj Patthi, Ashish Singla, Chandrasheker Janakiram, Venisha Pandita, Monika Prasad, Jishnu Krishna Kumar
INTRODUCTION: Periodontal disease and dental caries are the common oral conditions which cause loss of teeth, mostly molars. This further leads to Shortening of Dental Arch and Shortened Dental Arch (SDA) concept provides the overall requirements of functional dentition at reduced cost without compromising the health. AIM: The aim of the present study was to assess the Knowledge, Attitude and Practices (KAP) towards SDA concept among dentists of Ghaziabad city (Uttar Pradesh, India)...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28198969/celebrating-the-25-years-of-the-journal-of-applied-oral-science
#3
EDITORIAL
Karin Hermana Neppelenbroek, Vanessa Soares Lara
No abstract text is available yet for this article.
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28189064/oral-application-of-carbon-nanofibers-in-rats-increases-blood-concentration-of-il6-and-il10-and-decreases-locomotor-activity
#4
Nina Vitalievna Sayapina, Tatyana Anantolievna Batalova, Alexander Alexandrovich Sergievich, Mikhail Anatolievich Shtarberg, Eugeny Alexandrovich Borodin, Pavel Pavlovich Khoroshikh, Vladimir Victorovich Chaika, Vladimir Valerievich Kodintsev, Alexey Anatolievich Vedyagin, Ilya Vladimirovich Mishakov, Antonis Vakis, Petra Henrich-Noack, Aristidis M Tsatsakis, Ayse Basak Engin, Kirill Golokhvast
Carbon nanofibers (CNF) are versatile nanomaterials that are widely used in various fields of science and technology. As a consequence, animals as well as humans may be exposed to such compounds via different routes. We hypothesized that oral intake of CNF will lead to an inflammatory reaction and consequently induce behavioral impairments. To address this issue, rats were fed with 500mg/kgCNF for 14days and their locomotor activity, emotional status and cognition were quantified by testing the animals in an open field set-up, elevated plus maze and in the universal problem solving box which provides information about motivation and cognition...
January 24, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28187435/glucose-transporter-glut1-expression-and-clinical-outcome-in-solid-tumors-a-systematic-review-and-meta-analysis
#5
Ji Wang, Chenyang Ye, Cong Chen, Hanchu Xiong, Binbin Xie, Jichun Zhou, Yongxia Chen, Shu Zheng, Linbo Wang
Glucose transporter 1 (GLUT1), the uniporter protein encoded by the SLC2A1 gene, is a key rate-limiting factor in the transport of glucose in cancer cells, and frequently expressed in a significant proportion of human cancers. Numerous studies have reported paradoxical evidence of the relationship between GLUT1 expression and prognosis in solid human tumors. To address this discrepancy, we conducted a thorough search of Pubmed and Web of Science for studies evaluating the expression of GLUT1 and overall survival (OS) and disease-free survival (DFS) in patients with solid cancer from 1993 to April 2016...
February 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28185765/proceedings-of-the-2016-santa-fe-bone-symposium-new-concepts-in-the-management-of-osteoporosis-and-metabolic-bone-diseases
#6
REVIEW
E Michael Lewiecki, John P Bilezikian, Susan V Bukata, Pauline Camacho, Bart L Clarke, Michael R McClung, Paul D Miller, John Shepherd
The Santa Fe Bone Symposium is an annual meeting of healthcare professionals and clinical researchers that details the clinical relevance of advances in knowledge of skeletal diseases. The 17th Santa Fe Bone Symposium was held in Santa Fe, New Mexico, USA, on August 5-6, 2016. The program included plenary lectures, oral presentations by endocrinology fellows, meet-the-professor sessions, and panel discussions, all aimed to provide ample opportunity for interactive discussions among all participants. Symposium topics included recent developments in the translation of basic bone science to patient care, new clinical practice guidelines for postmenopausal osteoporosis, management of patients with disorders of phosphate metabolism, new and emerging treatments for rare bone diseases, strategies to enhance fracture healing, and an update on Bone Health Extension for Community Healthcare Outcomes, using a teleconferencing platform to elevate the level of knowledge of healthcare professionals in underserved communities to deliver best practice care for skeletal diseases...
February 6, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28182082/cytomorphometric-analysis-and-morphological-assessment-of-oral-exfoliated-cells-in-type-2-diabetes-mellitus-and-healthy-individuals-a-comparative-study
#7
Khushboo Sahay, Shweta Rehani, Priyanka Kardam, Madhumani Kumra, Rashi Sharma, Nisha Singh
CONTEXT: Oral exfoliative cytology is a simple, nonaggressive technique that is well accepted by patients. Therefore, it is an attractive option, which aids in the diagnosis and observation of epithelial atypias associated with oral mucosal diseases. AIMS: The aim of this study was to evaluate and compare the quantitative and qualitative alterations in exfoliative smears from type 2 diabetics and healthy individuals. PATIENTS AND METHODS: The study includes 30 type 2 diabetics and 30 healthy persons of both sexes...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28181687/acupuncture-for-acute-hordeolum
#8
REVIEW
Ke Cheng, Andrew Law, Menghu Guo, L Susan Wieland, Xueyong Shen, Lixing Lao
BACKGROUND: Hordeolum is an acute, purulent inflammation of the eyelid margin usually caused by obstructed orifices of the sebaceous glands of the eyelid. The condition, which affects sebaceous glands internally or externally, is common. When the meibomian gland in the tarsal plate is affected, internal hordeolum occurs, while when the glands of Zeis or Moll associated with eyelash follicles are affected, external hordeolum, or stye occurs. The onset of hordeolum is usually self limited, and may resolve in about a week with spontaneous drainage of the abscess...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28180945/effect-of-magnesium-supplementation-on-lipid-profile-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Luis E Simental-Mendía, Mario Simental-Mendía, Amirhossein Sahebkar, Martha Rodríguez-Morán, Fernando Guerrero-Romero
PURPOSE: We performed a meta-analysis of randomized controlled trials (RCTs) in order to evaluate the effect of oral magnesium supplementation on lipid profile of both diabetic and non-diabetic individuals. METHODS: PubMed-Medline, SCOPUS, Web of Science, and Google Scholar databases were searched (from inception to February 23, 2016) to identify RCTs evaluating the effect of magnesium on lipid concentrations. A random-effects model and generic inverse variance method were used for quantitative data synthesis...
February 9, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28179928/prevalence-of-extra-roots-in-permanent-mandibular-first-molars-in-iranian-population-a-cbct-analysis
#10
Saeed Rahimi, Hadi Mokhtari, Bahram Ranjkesh, Masoomeh Johari, Mohammad Frough Reyhani, Shahriar Shahi, Sina Seif Reyhani
INTRODUCTION: Having knowledge about the anatomy of root canal system is essential for success of endodontic treatment. The present study used cone-beam computed tomography (CBCT), to evaluate the prevalence of third root in mandibular first molars in a selected Iranian population. METHODS AND MATERIALS: A total of 386 CBCT images from subjects referred to oral and maxillofacial radiology department of dental faculty of Tabriz University of Medical Sciences from 2011 to 2013 were selected and evaluated for this study and the cases with well-developed permanent mandibular first molars were included...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28174362/most-frequent-oral-lesions-in-patients-with-type-2-diabetes-mellitus
#11
Micheline S Trentin, Georgia Verardi, Michele De C Ferreira, João P de Carli, Soluete O da Silva, Igor Fp Lima, Luiz R Paranhos
AIM: Type 2 diabetes mellitus (DM2) is a chronic disease caused by the underproduction of insulin in the organism and it is considered a risk factor to periodontal disease. MATERIALS AND METHODS: This study performed a cross-sectional research on the main oral changes in patients with DM2 and nondiabetics, in Passo Fundo, Rio Grande do Sul, Brazil. The sample included 116 patients examined at the Diabetes Outpatient Clinic of the School of Medicine of the University of Passo Fundo (UPF) and 134 nondiabetic patients examined at the Examinations, Triage, and Emergency Sector of the School of Dentistry of UPF...
February 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28170093/topical-treatments-for-blepharokeratoconjunctivitis-in-children
#12
REVIEW
Michael O'Gallagher, Catey Bunce, Melanie Hingorani, Frank Larkin, Stephen Tuft, Annegret Dahlmann-Noor
BACKGROUND: Blepharokeratoconjunctivitis (BKC) is a type of inflammation of the surface of the eye and eyelids that involves changes of the eyelids, dysfunction of the meibomian glands, and inflammation of the conjunctiva and cornea. Chronic inflammation of the cornea can lead to scarring, vascularisation and opacity. BKC in children can cause significant symptoms including irritation, watering, photophobia and loss of vision from corneal opacity, refractive error or amblyopia.Treatment of BKC is directed towards modification of meibomian gland disease and the bacterial flora of lid margin and conjunctiva, and control of ocular surface inflammation...
February 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28166787/the-efficacy-of-protected-mealtimes-in-hospitalised-patients-a-stepped-wedge-cluster-randomised-controlled-trial
#13
Judi Porter, Terry P Haines, Helen Truby
BACKGROUND: Protected Mealtimes is an intervention developed to address the problem of malnutrition in hospitalised patients through increasing positive interruptions (such as feeding assistance) whilst minimising unnecessary interruptions (including ward rounds and diagnostic procedures) during mealtimes. This clinical trial aimed to measure the effect of implementing Protected Mealtimes on the energy and protein intake of patients admitted to the subacute setting. METHODS: A prospective, stepped wedge cluster randomised controlled trial was undertaken across three hospital sites at one health network in Melbourne, Australia...
February 7, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28166255/occlusal-stabilization-splint-for-patients-with-temporomandibular-disorders-meta-analysis-of-short-and-long-term-effects
#14
Jovana Kuzmanovic Pficer, Slobodan Dodic, Vojkan Lazic, Goran Trajkovic, Natasa Milic, Biljana Milicic
BACKGROUND: Psychological discomfort, physical disability and functional limitations of the orofacial system have a major impact on everyday life of patients with temporomandibular disorders (TMDs). In this study we sought to determine short and long term effects of stabilization splint (SS) in treatment of TMDs, and to identify factors influencing its efficacy. METHODS: MEDLINE, Web of Science and EMBASE were searched for randomized controlled trials (RCTs) comparing SS to: non-occluding splint, occlusal oral appliances, physiotherapy, behavioral therapy, counseling and no treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28163858/parents-oral-health-literacy-and-its-impact-on-their-children-s-dental-health-status
#15
Effat Khodadadi, Ayshe Niknahad, Mohammad Mehdi Naghibi Sistani, Mina Motallebnejad
INTRODUCTION: Because parents play a key role in children's dental health, the aim of this study was to determine the relationship between parents' oral health literacy (OHL) and their children's dental health status in Babol, Iran. METHODS: In this cross sectional study a total of 384 children aged 21 months to 84 months who attended the dental clinic of Babol University of Medical Sciences between September 2015 and February 2016 were examined. We measured dmft index only for primary dentition; during examination the accompanying parent completed the "Oral Health Literacy-Adults Questionnaire"...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28160523/orofacial-functions-in-experimental-models-of-cerebral-palsy-a-systematic-review
#16
REVIEW
Diego Cabral Lacerda, Kelli Nogueira Ferraz-Pereira, André Terácio, Bárbara Juacy Rodrigues Costa de Santana, Omar Guzman Quevedo, Raul Manhães-de-Castro, Ana Elisa Toscano
BACKGROUND: Children who suffer from cerebral palsy (CP) often present comorbidities in the form of orofacial dysfunctions. Studies in animals have contributed to elaborate potential therapies aimed at minimizing the chronic disability of the syndrome. OBJECTIVE: To systematically review the scientific literature regarding the possible effects that experimental models of CP can have on orofacial functions. METHODS: Two independent authors conducted a systematic review in the electronic databases Medline, Scopus, CINAHL, Web of Science and Lilacs, using Mesh and Decs terms in animal models...
February 4, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28154519/mining-the-proteome-of-fusobacterium-nucleatum-subsp-nucleatum-atcc-25586-for-potential-therapeutics-discovery-an-in-silico-approach
#17
Abdul Musaweer Habib, Md Saiful Islam, Md Sohel, Md Habibul Hasan Mazumder, Mohd Omar Faruk Sikder, Shah Md Shahik
The plethora of genome sequence information of bacteria in recent times has ushered in many novel strategies for antibacterial drug discovery and facilitated medical science to take up the challenge of the increasing resistance of pathogenic bacteria to current antibiotics. In this study, we adopted subtractive genomics approach to analyze the whole genome sequence of the Fusobacterium nucleatum, a human oral pathogen having association with colorectal cancer. Our study divulged 1,499 proteins of F. nucleatum, which have no homolog's in human genome...
December 2016: Genomics & Informatics
https://www.readbyqxmd.com/read/28152849/a-novel-auditing-procedure-for-an-oral-chemotherapy-process-improvement-project
#18
R Alejandro Sica, Katherine Sencion, Amer Sidani, Christina Haaf, Diana Sullivan, Neeta K Venepalli
: 164 Background: A process to standardize ordering, documentation, and administration of inpatient oral chemotherapy was implemented at the University of Illinois Hospital and Health Sciences System. The process requires oncology clinician review and endorsement of inpatient oral chemotherapy drug orders via an oral chemotherapy note within the electronic health record. Pharmacists are instructed to reject oral chemotherapy drug orders that lack this required documentation. A novel auditing procedure was established in order to track adherence to these new requirements and provide real time and adaptable feedback to front-line staff critical to the project's success...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152723/a-multidisciplinary-quality-improvement-project-to-improve-the-safety-of-oral-chemotherapy-in-hospitalized-patients
#19
Amer Sidani, Gelenis Calzadilla Domingo, Diana Sullivan, Katherine Sencion, Dominic Ho, Christina Haaf, Adam Bursua, Neeta K Venepalli
: 110 Background: At the University of Illinois Hospital and Health Sciences System (UIC), inpatient IV chemotherapy administration occurs in the setting of specific protocols and multidisciplinary safety assessments while oral chemotherapy agent (OCA) inpatient administration occurs less formally. Baseline 8 week review of 174 admissions to the oncology service revealed that of 16 patients (9.2%) on outpatient OCA, 50% received OCAs while inpatient, with 12. 55% having a formal chemotherapy note in place...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145825/emerging-technologies-in-solid-drug-delivery-an-interview-with-nadia-passerini
#20
Nadia Passerini
Nadia Passerini is interviewed by Hannah Makin, Commission Editor. Nadia Passerini is Associate Professor of Pharmaceutical Technology at the University of Bologna (Bologna, Italy). She obtained the degree in Pharmaceutical Chemistry and Technology at the University of Bologna in 1992 and the PhD in Pharmaceutical Science in 1997. Her research focuses on the study of drug delivery systems, developing new technologies and new apparatus for the production of solid dosage forms (microparticles, granules and tablets), which can optimize the bioavailability of drugs according to the specific needs of the therapy...
January 2017: Therapeutic Delivery
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