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https://www.readbyqxmd.com/read/28104121/liver-failure-from-ultra-short-bowel-syndrome-on-the-intestinal-transplant-waiting-list-a-retrospective-study
#1
Y Noguchi, T Ueno, R Matsuura, T Kodama, K Deguchi, S Umeda, T Yamamichi, K Nakahata, M Zenitani, Y Takama, H Yamanaka, Y Tazuke, H Okuyama
BACKGROUND: Patients with intestinal failure (IF) are candidates for intestinal transplantation (ITx). In Japan, these patients have few opportunities to undergo cadaveric ITx because of low rates of organ donation. The donor criteria and recipient priority for ITx are still unknown. We reviewed our cases of IF to investigate which patients should be prioritized for ITx. METHODS: Patients with IF who were registered as candidates for cadaveric ITx between January 2010 and November 2015 in our institute were included in this retrospective study...
January 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28099958/distance-from-left-renal-vein-to-inferior-pancreaticoduodenal-artery-a-landmark-for-identifying-inferior-pancreaticoduodenal-artery-in-pancreatoduodenectomy
#2
Yoshito Tomimaru, Kaishu Tanaka, Kozo Noguchi, Hisanori Hatano, Hidetoshi Eguchi, Keizo Dono
BACKGROUND/AIM: During pancreatoduodenectomy, early ligation of major afferent arteries to pancreatic head prior to dissection of the corresponding veins may reduce intraoperative bleeding. Inferior pancreaticoduodenal artery (IPDA), one of the major afferent arteries, is difficult to identify. We measured the distance from left renal vein to IPDA based on preoperative multi-detector row computed tomography (MDCT) images for use as a new landmark for IPDA. METHODS: The distance between left renal vein and IPDA was measured in 417 patients using MDCT images...
January 19, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28099070/laparoscopic-rectal-dissection-assisted-by-transanal-endoluminal-videoendoscopy-through-a-blunt-tip-trocar
#3
Emanuele Asti, Andrea Lovece, Luigi Bonavina
BACKGROUND AND AIMS: Laparoscopic resection is a well-established approach for colorectal cancer surgery. In patients with rectal cancer treated by neoadjuvant chemoradiotherapy, it may be difficult to identify a clear safety margin for endostapling and subsequent anastomosis. We designed an innovative technical approach to assist colorectal anastomosis in these patients. TECHNIQUE: A four-trocar laparoscopic approach is used. After exploration of the abdominal cavity, the left colic flexure is completely mobilized...
January 18, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28092913/umbilical-venous-catheter-malposition-is-associated-with-necrotizing-enterocolitis-in-premature-infants
#4
Mustafa Sulemanji, Khashayar Vakili, David Zurakowski, Wayne Tworetzky, Steven J Fishman, Heung Bae Kim
OBJECTIVE: The etiology of necrotizing enterocolitis (NEC) remains elusive despite known associations with several factors, including intestinal ischemia related to the effects of umbilical arterial catheterization on the mesenteric circulation. However, the role of the mesenteric venous circulation has yet to be studied as a potential cause of NEC. We examined the association between umbilical venous catheter (UVC) position and the development of NEC in premature infants. DESIGN: A prospective cohort study was performed to examine the effect of UVC on portosystemic shunting via the ductus venosus (DV) and its potential role in NEC...
January 17, 2017: Neonatology
https://www.readbyqxmd.com/read/28076021/radiologic-assessment-of-native-renal-vasculature-a-multimodality-review
#5
Sayf Al-Katib, Monisha Shetty, Syed Mohammad A Jafri, Syed Zafar H Jafri
A wide range of clinically important anatomic variants and pathologic conditions may affect the renal vasculature, and radiologists have a pivotal role in the diagnosis and management of these processes. Because many of these entities may not be suspected clinically, renal artery and vein assessment is an essential application of all imaging modalities. An understanding of the normal vascular anatomy is essential for recognizing clinically important anatomic variants. An understanding of the protocols used to optimize imaging modalities also is necessary...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28075532/clinical-and-biochemical-characterization-of-the-prothrombin-belgrade-mutation-in-a-large-serbian-pedigree-new-insights-into-antithrombin-resistance-mechanism
#6
Predrag Miljic, Maja Gvozdenov, Yuki Takagi, Akira Takagi, Iva Pruner, Marija Dragojevic, Branko Tomic, Jelena Bodrozic, Tetsuhito Kojima, Dragica Radojkovic, Valentina Djordjevic
BACKGROUND: The recently reported c.1787G>A mutation in the prothrombin gene leads to Arg596Gln replacement in the protein molecule (prothrombin Belgrade). This substitution impairs binding of antithrombin to thrombin and results in inherited thrombophilia, known as antithrombin resistance. OBJECTIVES: We aimed to elucidate the clinical and biochemical characteristics of thrombophilia associated with antithrombin resistance in a large Serbian family with the prothrombin Belgrade mutation...
January 11, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28065379/selection-of-peripheral-intravenous-catheters-with-24-gauge-side-holes-versus-those-with-22-gauge-end-hole-for-mdct-a-prospective-randomized-study
#7
Akio Tamura, Kenichi Kato, Masayoshi Kamata, Tomohiro Suzuki, Michiko Suzuki, Manabu Nakayama, Makiko Tomabechi, Tatsuhiko Nakasato, Shigeru Ehara
PURPOSE: To compare the 24-gauge side-holes catheter and conventional 22-gauge end-hole catheter in terms of safety, injection pressure, and contrast enhancement on multi-detector computed tomography (MDCT). MATERIALS & METHODS: In a randomized single-center study, 180 patients were randomized to either the 24-gauge side-holes catheter or the 22-gauge end-hole catheter groups. The primary endpoint was safety during intravenous administration of contrast material for MDCT, using a non-inferiority analysis (lower limit 95% CI greater than -10% non-inferiority margin for the group difference)...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28058512/a-novel-approach-for-robotic-mobilization-of-the-splenic-flexure
#8
O Isik, C Benlice, E Gorgun
BACKGROUND: The techniques of robotic splenic flexure mobilization in the colorectal surgery setting are not well defined and have been challenging due to limited range of motion of the second-generation robotic platform in multiple quadrants. METHODS: This report describes a novel technique for robotic splenic flexure mobilization with medial-to-lateral approach without a need for robotic cart repositioning during left-sided colon and rectal surgery. The dissection is started with ligation of the inferior mesenteric artery and vein...
January 5, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28045757/left-colonic-bleeding-secondary-to-inferior-mesenteric-vein-stenosis
#9
Thang Q Le, Donald Romanelli
Lower gastrointestinal bleeding is most commonly associated with diverticulosis, ischemic colitis, vascular ectasia, and anorectal disease and less commonly associated with colonic malignancy. Infrequently, it is associated with mesenteric varices, a rare etiology that is not well documented in the radiology literature. We present a case of a 50-year-old man diagnosed as having intermittent left colonic bleeding from mesenteric varices due to a critical stenosis at the portal vein-inferior mesenteric vein confluence...
December 29, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28043760/endoscopic-ultrasonography-complements-computed-tomography-in-predicting-portal-or-superior-mesenteric-vein-resection-in-patients-with-borderline-resectable-pancreatic-carcinoma
#10
Evan S Glazer, Omar M Rashid, Jason B Klapman, Cynthia L Harris, Pamela J Hodul, Jose M Pimiento, Mokenge P Malafa
BACKGROUND: Current guidelines recommend computed tomographic (CT) scans for vascular staging of patients with pancreatic carcinoma; however, endoscopic ultrasonography (EUS) in these patients is not required and its utility in combination with CT scan is less well-defined. The purpose of this study is to explore the utility of EUS in addition to CT in identifying patients with borderline resectable pancreatic carcinoma (BRPC). METHODS: We reviewed our database of patients with BRPC who went to surgery with curative intent...
December 5, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28040229/-macroscopic-hematuria-secondary-to-nutcracker-syndrome-and-successful-endovascular-treatment
#11
Carlos A Hinojosa, Javier E Anaya-Ayala, Estefanía Boyer-Duck, Hugo Laparra-Escareno, Adriana Torres-Machorro, Rene Lizola
BACKGROUND: Nutcracker syndrome is a rare entity, and in the majority of cases is the result of extrinsic compression of the left renal vein between the superior mesenteric artery and the aorta, associated with functional stenosis. OBJECTIVE: To present the case of a 19-year-old female with no significant medical history with confirmed diagnosed of nutcracker syndrome treated successfully by endovascular means. CLINICAL CASE: She was referred to the Vascular Surgery Department with a 6-month history of macroscopic haematuria, after other aetiologies were ruled out...
December 28, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28031667/progression-of-thrombus-in-portal-vein-superior-mesenteric-vein-and-splenic-vein-even-on-anticoagulation-in-a-patient-with-ascending-colonic-malignancy-with-liver-metastasis-portal-vein-thrombosis-versus-portal-vein-tumor-thrombosis
#12
Ashish Sule, Annamarie Borja, Tay Jam Chin
Portal vein thrombosis (PVT) in a setting of liver metastasis is not easy to treat as it may be portal vein tumor thrombus (PVTT). A 77-year-old male patient was diagnosed as ascending colon carcinoma, underwent right hemicolectomy in 1991 with a recurrence in July 2009. In August 2009, he underwent computed tomography (CT) scan of the abdomen which showed evidence of superior mesenteric vein thrombosis with no liver metastasis. He was started with anticoagulation and decision was to treat long term. He was admitted with mesenteric artery ischemic symptoms in February 2012 on anticoagulation...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28029328/when-what-and-why-of-perioperative-treatment-of-potentially-curable-pancreatic-adenocarcinoma
#13
Kimberly Perez, Thomas E Clancy, Joseph D Mancias, Michael H Rosenthal, Brian M Wolpin
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
December 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28028193/smooth-muscle-endothelin-b-receptors-regulate-blood-pressure-but-not-vascular-function-or-neointimal-remodeling
#14
Eileen Miller, Alicja Czopek, Karolina M Duthie, Nicholas S Kirkby, Elisabeth E Fransen van de Putte, Sibylle Christen, Robert A Kimmitt, Rebecca Moorhouse, Raphael F P Castellan, Yuri V Kotelevtsev, Rhoda E Kuc, Anthony P Davenport, Neeraj Dhaun, David J Webb, Patrick W F Hadoke
The role of smooth muscle endothelinB (ETB) receptors in regulating vascular function, blood pressure (BP), and neointimal remodeling has not been established. Selective knockout mice were generated to address the hypothesis that loss of smooth muscle ETB receptors would reduce BP, alter vascular contractility, and inhibit neointimal remodeling. ETB receptors were selectively deleted from smooth muscle by crossing floxed ETB mice with those expressing cre-recombinase controlled by the transgelin promoter. Functional consequences of ETB deletion were assessed using myography...
February 2017: Hypertension
https://www.readbyqxmd.com/read/28012855/prostanoids-counterbalance-the-synergism-between-endothelin-1-and-angiotensin-ii-in-mesenteric-veins-of-trained-rats
#15
Agnaldo Bruno Chies, Priscilla Bianca de Oliveira, Patrícia de Souza Rossignoli, Rafaela de Fátima Ferreira Baptista, Roger William de Lábio, Spencer Luiz Marques Payão
Exercise-induced adaptations of the modulating mechanisms that influence the angiotensin (Ang II) responses assume different features depending on the venous bed. In femoral veins, exercise mobilizes vasodilator prostanoids to cooperate with NO in order to maintain reduced Ang II responses. On the other hand, exercise's influence on the Ang II responses in veins that drain blood from the mesenteric region has been poorly described. Therefore, the present study aimed to identify the effects of a single bout of exercise, as well as exercise training, on the Ang II responses in mesenteric veins...
December 21, 2016: Peptides
https://www.readbyqxmd.com/read/28008705/navigating-the-mesentery-part-ii-vascular-abnormalities-and-a-review-of-the-literature
#16
Jens Marius Nesgaard, Bojan V Stimec, Arne Olav Bakka, Bjorn Edwin, Dejan Ignjatovic
AIM: Vascular abnormalities present benefits and/or disadvantages for the patient undergoing surgery. The aims of this study were to define, classify, and demonstrate the courses and to assess the clinical value of arterial and venous abnormalities in the central mesentery. METHOD: We conducted a review of the anatomy of 340 patients planned for enrolment in the "Safe Radical D3 Right Hemicolectomy for Cancer through Preoperative Biphasic MDCT Angiography" trial, 312 of whom were submitted to surgery...
December 23, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28008384/circulating-cytokeratin-positive-cells-and-tumor-budding-in-colorectal-cancer
#17
Bruno Märkl, Narjes Wilhelms, Matthias Anthuber, Gerhard Schenkirsch, Günter Schlimok, Daniel Oruzio
AIM: To investigate whether circulating cytokeratin-positive (CK(+)) cells in the mesenteric blood of resected colorectal specimens are prognostic and correlate with tumor budding. METHODS: Fifty-six colorectal specimens were collected between 9/2007 and 7/2008. Blood from the mesenteric vein was drawn immediately after receiving the fresh and unfixed specimens in the pathology department. After separation of the mononuclear cells by Ficoll-Hypaque density-gradient centrifugation, cytological smears were immunocytochemically stained for CK18...
December 10, 2016: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27994632/calycosin-and-formononetin-induce-endothelium-dependent-vasodilation-by-the-activation-of-large-conductance-ca-2-activated-k-channels-bkca
#18
Hisa Hui Ling Tseng, Chi Teng Vong, George Pak-Heng Leung, Sai Wang Seto, Yiu Wa Kwan, Simon Ming-Yuen Lee, Maggie Pui Man Hoi
Calycosin and formononetin are two structurally similar isoflavonoids that have been shown to induce vasodilation in aorta and conduit arteries, but study of their actions on endothelial functions is lacking. Here, we demonstrated that both isoflavonoids relaxed rat mesenteric resistance arteries in a concentration-dependent manner, which was reduced by endothelial disruption and nitric oxide synthase (NOS) inhibition, indicating the involvement of both endothelium and vascular smooth muscle. In addition, the endothelium-dependent vasodilation, but not the endothelium-independent vasodilation, was blocked by BKCa inhibitor iberiotoxin (IbTX)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27986807/effects-of-4-multitargeted-receptor-tyrosine-kinase-inhibitors-on-regional-hemodynamics-in-conscious-freely-moving-rats
#19
Joanne J Carter, Laurice V Fretwell, Jeanette Woolard
VEGF inhibitors, including receptor tyrosine kinase inhibitors, are used as adjunct therapies in a number of cancer treatments. An emerging issue with these drugs is that most cause hypertension. To gain insight into the physiological mechanisms involved, we evaluated their regional hemodynamic effects in conscious rats. Male Sprague Dawley rats (350-450 g) were chronically implanted with pulsed Doppler flow probes (renal and mesenteric arteries, and the descending abdominal aorta) and catheters (jugular vein, peritoneal cavity, and distal abdominal aorta)...
December 16, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/27956806/therapeutic-efficacy-and-stent-patency-of-transhepatic-portal-vein-stenting-after-surgery
#20
Ung Bae Jeon, Chang Won Kim, Tae Un Kim, Ki Seok Choo, Joo Yeon Jang, Kyung Jin Nam, Chong Woo Chu, Je Ho Ryu
AIM: To evaluate portal vein (PV) stenosis and stent patency after hepatobiliary and pancreatic surgery, using abdominal computed tomography (CT). METHODS: Percutaneous portal venous stenting was attempted in 22 patients with significant PV stenosis (> 50%) - after hepatobiliary or pancreatic surgery - diagnosed by abdominal CT. Stents were placed in various stenotic lesions after percutaneous transhepatic portography. Pressure gradient across the stenotic segment was measured in 14 patients...
November 28, 2016: World Journal of Gastroenterology: WJG
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