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Marcel Betsch, Simon Thelen, Laila Santak, Monika Herten, Pascal Jungbluth, Daniel Miersch, Mohssen Hakimi, Michael Wild
BACKGROUND: All available treatment options for osteochondral and chondral defects do not restore hyaline cartilage and are limited to decreasing associated pain, and maintaining or improving joint function. The purpose of this study was to evaluate the potential of erythropoietin (EPO) in combination with bone marrow aspiration concentrate (BMAC) in the treatment of osteochondral defects of mini-pigs. METHODS: 14 Goettinger mini-pigs, in which a 6 × 10 mm osteochondral defect in the medial femoral condyle of both knee joints was created, were randomized into four groups: biphasic scaffold alone, scaffold with EPO, scaffold with BMAC and scaffold in combination with EPO and BMAC...
2014: PloS One
Richard Van Hoesel, Richard Ramsden, Martin Odriscoll
OBJECTIVES: To characterize some of the benefits available from using two cochlear implants compared with just one, sound-direction identification (ID) abilities, sensitivity to interaural time delays (ITDs) and speech intelligibility in noise were measured for a bilateral multi-channel cochlear implant user. METHODS: Sound-direction ID in the horizontal plane was tested with a bilateral cochlear implant user. The subject was tested both unilaterally and bilaterally using two independent behind-the-ear ESPRIT (Cochlear Ltd...
April 2002: Ear and Hearing
A M Halder, K D Zhao, S W Odriscoll, B F Morrey, K N An
It has been suggested that superior decentralization of the humeral head is a mechanical factor in the etiology of degenerative rotator cuff tears. This superior decentralization may be caused by muscular imbalance. The objective of this study was to investigate the contribution of individual shoulder muscles to superior stability of the glenohumeral joint. In 10 fresh frozen cadaver shoulders the tendons of the rotator cuff, teres major, latissimus, pectoralis major, deltoid and biceps were prepared. The shoulders were tested in a shoulder-loading device in 0 degrees, 30degrees, 60 degrees and 90 degrees of glenohumeral abduction...
March 2001: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
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