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bicarbonate contrast induced nephropathy

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https://www.readbyqxmd.com/read/29404930/comparative-efficacy-of-pharmacological-interventions-for-contrast-induced-nephropathy-prevention-after-coronary-angiography-a-network-meta-analysis-from-randomized-trials
#1
REVIEW
Wen-Qi Ma, Yu Zhao, Ying Wang, Xi-Qiong Han, Yi Zhu, Nai-Feng Liu
BACKGROUND: Contrast-induced nephropathy (CIN) is the major complication related to contrast media administration in patients after coronary angiography (CAG). However, inconsistent results have been published in the literature regarding the effects of pharmacological drugs on CIN prevention. We conducted a network meta-analysis to evaluate the relative efficacy of pharmacological interventions for the prevention of CIN. METHODS: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and ClinicalTrials...
February 5, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29340315/contrast-induced-nephropathy-and-oxygen-pretreatment-in-patients-with-impaired-renal-function
#2
Haruki Sekiguchi, Yoichi Ajiro, Yoshie Uchida, Kentaro Jujo, Kazunori Iwade, Naohide Tanaka, Ken Shimamoto, Yukio Tsurumi, Masatoshi Kawana, Nobuhisa Hagiwara
Introduction: Contrast-induced nephropathy is a complication following coronary angiography and percutaneous coronary intervention. Because contrast-induced nephropathy is a predictor of long-term mortality in patients with ischemic heart disease undergoing percutaneous coronary intervention, preventive strategies are required. We assessed the effects of periprocedural oxygenation on contrast-induced nephropathy among patients with pre-existing renal dysfunction. Methods: A total of 200 consecutive patients with impaired renal function (estimated glomerular filtration < 60 ml/min per 1...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29328017/-hydration-to-prevent-contrast-induced-nephropathy
#3
E J Hoorn, R Zietse
In 2007, a national guideline was issued in the Netherlands to prevent contrast-induced nephropathy. This guideline recommended preventive hydration with 0.9% NaCl in patients with reduced estimated glomerular filtration rate (eGFR 30-69 ml/min/1.73 m2) prior to administration of contrast. The recent AMACING study compared hydration versus no hydration, and found that hydration did not prevent contrast-induced nephropathy but did lead to complications and higher costs. The latest 2017 guideline recommends hydration only for patients with eGFR < 30 ml/min/1...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29150416/-bicarbonate-from-physiology-to-treatment-for-all-clinicians
#4
Julie Beaume, Antoine Braconnier, Thibault Dolley-Hitze, Jean-Philippe Bertocchio
Acid-base regulation is essential to maintain homeostasis in humans. Carbonic acid/bicarbonate (H2CO3/HCO3-) couple is the most predominant extracellular buffer to keep plasma pH within a physiological range. The ability to (re)generate such a buffer is a key milestone that necessitates to understand a precise physiology of both renal tubule and digestive tract. Here, we first reviewed renal and digestive cycles of bicarbonate in physiology. We also reviewed pathological findings where acid-base disequilibrium is involved and nutritional and/or alkali therapy could be necessary...
November 14, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28844518/usefulness-of-sodium-bicarbonate-for-the-prevention-of-contrast-induced-nephropathy-in-patients-undergoing-cardiac-resynchronization-therapy
#5
RANDOMIZED CONTROLLED TRIAL
Pau Alonso, Jorge Sanz, Ana García-Orts, Samuel Reina, Sonia Jiménez, Joaquín Osca, Oscar Cano, Ana Andrés, María José Sancho-Tello, Luis Martínez
The use of contrast media during cardiac resynchronization therapy (CRT) devices implantation is associated with the risk of contrast-induced nephropathy (CIN). The aim of this study was to evaluate the possible beneficial role of periprocedural intravenous volume expansion with isotonic saline and sodium bicarbonate solution in patients who undergo CRT implantation. Eligible patients were randomly assigned in a 1:1 ratio to receive hydration plus one-sixth molar sodium bicarbonate (study group) or not (control group)...
November 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28642116/contrast-induced-nephropathy-basic-concepts-pathophysiological-implications-and-prevention-strategies
#6
REVIEW
Charalampos Mamoulakis, Konstantinos Tsarouhas, Irini Fragkiadoulaki, Ioannis Heretis, Martin F Wilks, Demetrios A Spandidos, Christina Tsitsimpikou, Aristides Tsatsakis
Contrast-induced nephropathy (CIN) is reversible acute renal failure observed following administration of iodinated contrast media (CM) during angiographic or other medical procedures such as urography. There are various mechanisms through which CM develop their nephrotoxic effects, including oxidative stress and apoptosis. CIN is a real-life, albeit not very rare, entity. Exact pathophysiology remains obscure and no standard diagnostic criteria apply. The Acute Kidney Injury Network criteria was recently employed but its incidence/clinical significance warrants further clarification based on recent methodological advancements, because most published studies to date were contaminated by bias...
December 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28551197/-vitamin-c-sodium-bicarbonate-versus-sodium-bicarbonate-alone-in-preventing-contrast-induced%C3%A2-nephropathy
#7
L Laroussi, M Triki, Z Ibn Elhaj, A Ben Halima, M Boukhris, W Ben Amara, H Keskes, S Kraiem, D Lahidheb, S Marrakchi, I Kammoun, F Addad, S Kachboura
INTRODUCTION: Contrast-induced nephropathy (CIN) is a common and severe complication in interventional cardiology. OBJECTIVE: The aim of our study was to compare the incidence of contrast-induced nephropathy in two accelerated hydration protocols: the first one by the serum bicarbonate and the second combining the serum bicarbonate and oral vitamin C. METHODS: This is a multicenter prospective, randomized study conducted between October 2012 and May 2013, including 160 patients...
September 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28003574/sodium-bicarbonate-ascorbic-acid-combination-for-prevention-of-contrast-induced-nephropathy-in-chronic-kidney-disease-patients-undergoing-catheterization
#8
RANDOMIZED CONTROLLED TRIAL
Kota Komiyama, Takashi Ashikaga, Dai Inagaki, Tomonori Miyabe, Marina Arai, Kiyotaka Yoshida, Satoshi Miyazawa, Akihiro Nakada, Iwanari Kawamura, Shinichiro Masuda, Sho Nagamine, Rintaro Hojo, Yuya Aoyama, Takaaki Tsuchiyama, Seiji Fukamizu, Takashi Shibui, Harumizu Sakurada
BACKGROUND: Sodium bicarbonate and ascorbic acid have been proposed to prevent contrast-induced nephropathy (CIN). The present study evaluated the effect of their combined use on CIN incidence.Methods and Results:We prospectively enrolled 429 patients with chronic kidney disease (CKD: baseline estimated glomerular filtration rate <60 mL/min/1.73 m2) prior to elective coronary catheterization. CIN was defined as absolute (≥0.5 mg/dL) or relative (≥25%) increase in serum creatinine within 72 h...
January 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27485363/strategies-preventing-contrast-induced-nephropathy-after-coronary-angiography-a-comprehensive-meta-analysis-and-systematic-review-of-125-randomized-controlled-trials
#9
Sadegh Ali-Hassan-Sayegh, Seyed Jalil Mirhosseini, Zahra Ghodratipour, Zahra Sarrafan-Chaharsoughi, Elham Rahimizadeh, Ali Akbar Karimi-Bondarabadi, Fatemeh Haddad, Arezoo Shahidzadeh, Parisa Mahdavi, Ali-Mohammad Dehghan, Mahbube Tahernejad, Azadeh Shahidzadeh, Hamidreza Dehghan, Azam Ghanei, Mohammadreza Lotfaliani, Alexander Weymann, Mohamed Zeriouh, Aron-Frederik Popov, Anton Sabashnikov
This systematic review with meta-analysis sought to determine the strength of evidence for the effects of hydration (sodium bicarbonate [SB] and normal saline [NS]), supplementations ( N-acetylcysteine [NAC] and vitamin C), and some common drugs (adenosine antagonists [AAs], statins, loop diuretics, and angiotensin-converting enzyme inhibitors [ACEIs]) on the incidence of contrast-induced nephropathy (CIN) and requirement for hemodialysis after coronary angiography. After screening, a total of 125 trials that reported outcomes were identified...
May 2017: Angiology
https://www.readbyqxmd.com/read/27411777/the-high-risk-of-contrast-induced-nephropathy-in-patients-with-suspected-pulmonary-embolism-despite-three-different-prophylaxis-a-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Suleyman Turedi, Erkan Erdem, Yunus Karaca, Ozgur Tatli, Aynur Sahin, Suha Turkmen, Abdulkadir Gunduz
OBJECTIVE: The objective was to compare the protective effects of N-acetylcysteine (NAC) plus normal saline (NS), sodium bicarbonate (NaHCO3 ) plus NS, and NS alone in the prevention of contrast-induced nephropathy (CIN) after computed tomography pulmonary angiography (CTPA) in emergency patients. METHODS: This study was planned as a randomized, controlled clinical research. Patients undergoing contrast-enhanced CTPA on suspicion of pulmonary embolism (PE) in the emergency department and with at least one risk factor for development of CIN were included in one of three different prophylaxis groups...
October 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27404685/the-efficacy-of-n-acetylcysteine-plus-sodium-bicarbonate-in-the-prevention-of-contrast-induced-nephropathy-after-cardiac-catheterization-and-percutaneous-coronary-intervention-a-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Shi-Jie Zhao, Zhao-Shuang Zhong, Guo-Xian Qi, Wen Tian
BACKGROUND: The efficacy of combining use of N-acetylcysteine (NAC) and sodium bicarbonate (SOB) in the prevention of contrast-induced nephropathy (CIN) after cardiac catheterization and percutaneous coronary intervention (PCI) is unclear. METHODS: All relevant studies that compared the effect of combining the use of NAC and SOB with individual use on CIN in patients undergoing cardiac catheterization and PCI were identified by searching the databases including Pubmed, Embase, Cochrane Library, and Web of Science without time and language limitation...
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27227933/sodium-bicarbonate-prevents-contrast-induced-nephropathy-in-addition-to-theophylline-a-randomized-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
Wolfgang Huber, Toni Huber, Stephan Baum, Michael Franzen, Christian Schmidt, Thomas Stadlbauer, Analena Beitz, Roland M Schmid, Sebastian Schmid
In this study, we investigated whether hydration with sodium bicarbonate is superior to hydration with saline in addition to theophylline (both groups) in the prophylaxis of contrast-induced nephropathy (CIN). It was a prospective, randomized, double-blinded study in a university hospital on 2 general intensive care units (63% of investigations) and normal wards.After approval of the local ethics committee and informed consent 152 patients with screening serum creatinine ≥1.1 mg/dL and/or at least 1 additional risk factor for CIN undergoing intravascular contrast media (CM) exposure were randomized to receive a total of 9 mL/kg bicarbonate 154 mmol/L (group B; n = 74) or saline 0...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27215244/na-k-citrate-versus-sodium-bicarbonate-in-prevention-of-contrast-induced-nephropathy
#13
RANDOMIZED CONTROLLED TRIAL
Sameh Mohamed Abouzeid, Hossam E ElHossary
Contrast-induced nephropathy (CIN) is one of the important complications of radiographic procedures, especially in patients with chronic kidney disease. It is also one of the common causes of acute kidney injury. The pathogenesis is postulated to be the effect of oxygen- free radicals and hyperosmolar stress on the renal medulla. It is reported that the production of superoxide is most active at acid environment. K/Na citrate is well known as a urine alkalinization medium, and this has been evaluated earlier with standard hydration for reduction of CIN and was stated to be efficient...
May 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27054007/evaluation-of-different-sodium-bicarbonate-regimens-for-the-prevention-of-contrast-medium-induced-nephropathy
#14
Sameh Abouzeid, Osama Mosbah
INTRODUCTION: The rapid decline in renal function caused by radiographic contrast agents usually is transient, but it can result in chronic kidney disease. The pathophysiology of contrast-induced nephropathy (CIN) is poorly understood, but it may include acute hypoxia-induced oxidative stress and free radicals generated within the acid environment of the renal medulla. Thus, the alkalization of urine by sodium bicarbonate has been regarded as resulting in the reduction of CIN. The aim of this study was to determine whether a long-duration sodium bicarbonate regimen is more effective than a short-duration regimen in reducing CIN...
February 2016: Electronic Physician
https://www.readbyqxmd.com/read/27045874/effects-of-combination-therapy-of-statin-and-n-acetylcysteine-for-the-prevention-of-contrast-induced-nephropathy-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#15
Soo Hwan Park, Myung Ho Jeong, In Hyae Park, Jin Soo Choi, Jung Ae Rhee, In Soo Kim, Min Cheol Kim, Jae Yeong Cho, Doo Sun Sim, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
BACKGROUND: Acute myocardial infarction (AMI) is a risk factor for contrast-induced nephropathy (CIN). We investigated whether pretreatment with statin, N-acetylcysteine (NAC) and sodium bicarbonate (NaHCO3) reduces the risk of CIN. METHODS: We conducted a prospective trial and enrolled a total of 334 ST-segment elevation myocardial infarction (STEMI) patients. Patients were divided into four groups: Group I (statin 40mg), Group II (statin 80mg), Group III (statin 80mg plus NAC 1200mg) and Group IV (regimen of group III plus NaHCO3 154mEq/L)...
June 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/26889416/intravenous-albumin-for-the-prevention-of-contrast-induced-nephropathy-in-patients-with-liver-cirrhosis-and-chronic-kidney-disease-undergoing-contrast-enhanced-ct
#16
Heejung Choi, Yoonjung Kim, Soo Min Kim, Junam Shin, Hye Ryoun Jang, Jung Eun Lee, Wooseong Huh, Yoon-Goo Kim, Ha Young Oh, Dae Joong Kim
BACKGROUND: The purpose of this study was to evaluate the incidence of contrast-induced nephropathy (CIN), and the effect of intravenous albumin for prophylaxis of CIN in patients with liver cirrhosis (LC) and chronic kidney disease (CKD). METHODS: We conducted a retrospective study of 81 subjects with LC and CKD (estimated glomerular filtration rate (eGFR)<60 mL/min/1.73 m(2)) who underwent contrast-enhanced computed tomography (CT). Patients received either isotonic sodium bicarbonate solution (3 mL/kg for 1 h before CT and 1 mL/kg/h for 6 h after CT) or albumin (20% albumin, 25 mL for 1 h before CT and 75 mL for 6 h after CT)...
June 2012: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/26830221/effectiveness-of-prevention-strategies-for-contrast-induced-nephropathy-a-systematic-review-and-meta-analysis
#17
REVIEW
Rathan M Subramaniam, Catalina Suarez-Cuervo, Renee F Wilson, Sharon Turban, Allen Zhang, Cheryl Sherrod, Jonathan Aboagye, John Eng, Michael J Choi, Susan Hutfless, Eric B Bass
BACKGROUND: N-acetylcysteine, sodium bicarbonate, statins, and ascorbic acid have been studied for reducing contrast-induced nephropathy (CIN). PURPOSE: To evaluate the comparative effectiveness of interventions to reduce CIN in adults receiving contrast media. DATA SOURCES: MEDLINE, EMBASE, Cochrane Library, ClinicalTrials.gov, and Scopus databases through June 2015. Risk of bias and overall strength of evidence (SOE) of studies were assessed...
March 15, 2016: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26759720/sodium-bicarbonate-prophylactic-therapy-in-the-prevention-of-contrast-induced-nephropathy-in-patients-admitted-to-the-intensive-care-unit-of-a-teaching-hospital-a-retrospective-cohort-study
#18
Nicole Lefel, Loes Janssen, Jos le Noble, Norbert Foudraine
BACKGROUND: Intravenously administered iodine-containing contrast medium (CM) is associated with the development of contrast-induced nephropathy (CIN). Data on the effectiveness of sodium bicarbonate therapy in the prevention of CIN are controversial. Furthermore, the incidence of and risk factors for CIN in intensive care unit (ICU) patients are poorly defined. We investigated the effectiveness of sodium bicarbonate prophylaxis and the incidence of and risk factors for CIN in a heterogeneous ICU population...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/26600623/sodium-bicarbonate-versus-isotonic-saline-solution-to-prevent-contrast-induced-nephropathy-a-systematic-review-and-meta-analysis
#19
REVIEW
Carlos Andres Zapata-Chica, Diana Bello Marquez, Lina Maria Serna-Higuita, John Fredy Nieto-Ríos, Fabian David Casas-Arroyave, Jorge Hernando Donado-Gómez
INTRODUCTION: Contrast-induced nephropathy is one of the main causes of acute kidney injury and increased hospital-acquired morbidity and mortality. The use of sodium bicarbonate for nephroprotection has emerged as a preventative strategy; however, its efficacy is controversial compared to other strategies, such as hydration using 0.9% saline solution. OBJECTIVE: To compare the effectiveness of sodium bicarbonate vs. hydration using 0.9% saline solution to prevent contrast-induced acute kidney injury...
September 30, 2015: Colombia Médica: CM
https://www.readbyqxmd.com/read/26301645/comparison-of-combination-therapy-of-high-dose-oral-n-acetylcysteine-and-intravenous-sodium-bicarbonate-hydration-with-individual-therapies-in-the-reduction-of-contrast-induced-nephropathy-during-cardiac-catheterisation-and-percutaneous-coronary-intervention
#20
RANDOMIZED CONTROLLED TRIAL
Eric Chong, Kian-Keong Poh, Qingshu Lu, James Jun-Jie Zhang, Ning Tan, Xu Min Hou, Hean-Yee Ong, Aizai Azan, Shao-Liang Chen, Ji-Yan Chen, Rosli Mohd Ali, Wei-Yi Fang, Titus Wai Leong Lau, Huay-Cheem Tan
INTRODUCTION: N-acetylcysteine (NAC) and sodium bicarbonate (SOB) therapies may prevent contrast-induced nephropathy (CIN). However, the efficacy of using combination over individual therapies was not established, and there was no large randomised study comparing abbreviated SOB therapy with conventional sustained saline pre-hydration with oral NAC. METHODS: In a multi-centre, open-label, randomised, controlled trial (NCT00497328), we prospectively enrolled 548 patients with at least moderate renal impairment undergoing cardiac catheterisation with or without percutaneous coronary intervention...
December 15, 2015: International Journal of Cardiology
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