Giancarlo Logroscino, Marco Piccininni, Caroline Graff, Orla Hardiman, Albert C Ludolph, Fermin Moreno, Markus Otto, Anne M Remes, James B Rowe, Harro Seelaar, Eino Solje, Elka Stefanova, Latchezar Traykov, Vesna Jelic, Melissa Taheri Rydell, Niall Pender, Sarah Anderl-Straub, Myriam Barandiaran, Alazne Gabilondo, Johanna Krüger, Alexander G Murley, Timothy Rittman, Emma L van der Ende, John C van Swieten, Päivi Hartikainen, Gorana Mandic Stojmenovic, Shima Mehrabian, Luisa Benussi, Antonella Alberici, Maria Teresa Dell'Abate, Chiara Zecca, Barbara Borroni
IMPORTANCE: Diagnostic incidence data for syndromes associated with frontotemporal lobar degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic approaches. OBJECTIVE: To assess the incidence of FTLD across Europe. DESIGN, SETTING, AND PARTICIPANTS: The Frontotemporal Dementia Incidence European Research Study (FRONTIERS) was a retrospective cohort study conducted from June 1, 2018, to May 31, 2019, using a population-based registry from 13 tertiary FTLD research clinics from the UK, the Netherlands, Finland, Sweden, Spain, Bulgaria, Serbia, Germany, and Italy and including all new FTLD-associated cases during the study period, with a combined catchment population of 11 023 643 person-years...
March 1, 2023: JAMA Neurology