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Transient ischaemic attack

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https://www.readbyqxmd.com/read/29158247/predictive-values-of-referrals-for-transient-ischaemic-attack-from-first-contact-health-care-a-systematic-review
#1
Rebecca Kandiyali, Daniel S Lasserson, Penny Whiting, Alison Richards, Jonathan Mant
BACKGROUND: Over 150 000 cases of suspected transient ischaemic attack (TIA) are referred to outpatient clinics in England each year. The majority of referrals are made by GPs. AIM: This study aimed to identify how many patients referred to a TIA clinic actually have TIA (that is, calculate the positive predictive value [PPV] of first-contact healthcare referral) and to record the alternative diagnoses in patients without TIA, in order to determine the optimal service model for patients with suspected TIA...
November 20, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29148156/long-term-outcomes-for-different-surgical-strategies-to-treat-left-ventricular-outflow-tract-obstruction-in-hypertrophic-cardiomyopathy
#2
Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P Guttmann, Antonis Pantazis, Maria Tome-Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G A McGregor, Perry M Elliott
AIMS: Surgical intervention is used to treat dynamic left ventricular outflow tract obstruction (LVOTO) in hypertrophic cardiomyopathy. This study assesses the effect of different surgical strategies on long-term mortality and morbidity. METHODS AND RESULTS: In total, 347 patients underwent surgical intervention for LVOTO (1988-2015). Group A (n = 272) underwent septal myectomy; Group B (n = 33), septal myectomy and mitral valve (MV) repair; Group C (n = 22), myectomy and MV replacement; and Group D (n = 20), MV replacement alone...
November 16, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29130000/knowledge-of-stroke-risk-factors-and-warning-signs-in-patients-with-recurrent-stroke-or-recurrent-transient-ischaemic-attack-in-thailand
#3
Jittima Saengsuwan, Pathitta Suangpho, Somsak Tiamkao
Stroke is a global burden. It is not known whether patients who are most at risk of stroke (recurrent stroke or recurrent transient ischaemic attack) have enough knowledge of stroke risk factors and warning signs. The aim of this study was to assess the knowledge of stroke risk factors and warning signs in this high-risk population. We performed a cross-sectional questionnaire-based study of patients with recurrent stroke or recurrent TIA admitted to Srinagarind Hospital and Khon Kaen Hospital, Thailand. A total of 140 patients were included in the study (age 65...
2017: Neurology Research International
https://www.readbyqxmd.com/read/29096029/safety-and-efficacy-of-minimalist-approach-in-transfemoral-transcatheter-aortic-valve-replacement-insights-from-the-optimized-transcatheter-valvular-intervention-transcatheter-aortic-valve-implantation-ocean-tavi-registry
#4
Soh Hosoba, Masanori Yamamoto, Kayoko Shioda, Mitsuru Sago, Yutaka Koyama, Tetsuro Shimura, Ai Kagase, Norio Tada, Toru Naganuma, Motoharu Araki, Futoshi Yamanaka, Shinichi Shirai, Yusuke Watanabe, Kentaro Hayashida
OBJECTIVES: Favourable results have been reported for monitored anaesthesia care that includes local anaesthesia and conscious sedation [minimalist approach (MA)] for transfemoral transcatheter aortic valve replacement (TAVR). However, the efficacy of MA is still controversial in Japan. We describe our experience from a Japanese multicentre registry. METHODS: Between October 2013 and April 2016, 1215 consecutive Japanese patients with symptomatic, severe aortic stenosis undergoing TAVR with self-expandable or balloon-expandable valves were prospectively included in the Optimized transCathEter vAlvular intervention-Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry...
October 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29064045/long-term-outcome-of-catheter-ablation-and-other-form-of-therapy-for-electrical-storm-in-patients-with-implantable-cardioverter-defibrillators
#5
Stanislaw Morawski, Patrycja Pruszkowska, Beata Sredniawa, Radoslaw Lenarczyk, Zbigniew Kalarus
PURPOSE: Radiofrequency catheter ablation (RFCA) for electrical storm (ES) has become a widely used therapeutic method. Its effectiveness in comparison to other forms of ES treatment is however uncertain. METHODS: This single-centre retrospective study investigated the long-term clinical outcome after RFCA for ES and compared long-time effects of ablation to other forms of treatment. The study population consisted of 70 consecutive patients hospitalised between January 2010 and June 2015 due to ES...
October 24, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29049563/red-cell-distribution-width-is-a-prognostic-marker-of-perioperative-stroke-in-patients-undergoing-cardiac-valve-surgery
#6
Piotr Duchnowski, Tomasz Hryniewiecki, Mariusz Kusmierczyk, Piotr Szymanski
OBJECTIVES: Numerous studies have shown that elevated red cell distribution width (RDW) is associated with poor outcomes in patients with cardiovascular diseases such as coronary artery disease, peripheral artery disease or stroke. The usefulness of the RDW as a predictor of perioperative stroke in patients with valve disease undergoing valve surgery is currently unknown. The aim of the study was to evaluate the prognostic value of RDW for stroke in the early postoperative period in patients undergoing valve replacement or repair surgery...
July 7, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29044586/males-with-prolactinoma-are-at-increased-risk-of-incident-cardiovascular-disease
#7
Konstantinos A Toulis, Tim Robbins, Narendra Reddy, Balachandran Kumarendran, Krishna Gokhale, Haren Wijesinghe, Kar Keung Cheng, Niki Karavitaki, John Wass, Krishnarajah Nirantharakumar
OBJECTIVE: To investigate whether the risk of incident cardiovascular disease (CVD) is increased in patients with prolactinoma. DESIGN: Population-based, retrospective, open-cohort study using The Health Improvement Network (THIN) database. PATIENTS: 2,233 patients with prolactinoma and 10,355 matched controls (1:5 ratio) from UK General Practices contributing to THIN were included. Sex, age, body mass index, and smoking status were used as matching parametres...
October 16, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29016870/complications-of-pulmonary-vein-isolation-in-atrial-fibrillation-predictors-and-comparison-between-four-different-ablation-techniques-results-from-the-middelheim-pvi-registry
#8
Yves De Greef, Edwin Ströker, Bruno Schwagten, Kaspars Kupics, Jeroen De Cocker, Gian-Battista Chierchia, Carlo de Asmundis, Dirk Stockman, Ian Buysschaert
Aims: To define predictors of complications of pulmonary vein isolation (PVI) and compare safety between different ablation techniques. Methods and results: One thousand patients with atrial fibrillation (AF) (age 60 ± 10, 72% males, CHA2DS2-VASc score 1 ± 1) underwent PVI using various techniques: conventional PVI (CPVI) using mapping with irrigated point-per-point RF ablation (n = 576), multi-electrode RF ablation with the pulmonary vein ablation catheter (PVAC) (n = 272) or high density mesh ablator (HDMA) (n = 59) and cryoballoon (CB) ablation (n = 93)...
August 3, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016769/safety-and-efficiency-of-porous-tip-contact-force-catheter-for-drug-refractory-symptomatic-paroxysmal-atrial-fibrillation-ablation-results-from-the-smart-sf-trial
#9
Larry A Chinitz, Daniel P Melby, Francis E Marchlinski, Craig Delaughter, Robert S Fishel, George Monir, Anshul M Patel, Douglas N Gibson, Charles A Athill, Lee Ming Boo, Robert Stagg, Andrea Natale
Aims: THERMOCOOL SMARTTOUCH® SF Catheter is a new contact-force (CF)-sensing catheter with 56-hole porous tip designed for improved cooling and reduced fluid delivery compared with a standard 6-hole open-irrigated catheter. The SMART SF study examined the periprocedural safety, acute effectiveness, and procedural efficiency of the catheter for drug-refractory symptomatic paroxysmal atrial fibrillation (PAF) ablation. Methods and results: The prospective, open-label, non-randomized SMART-SF was conducted at 17 US sites...
August 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016758/non-vitamin-k-antagonist-oral-anticoagulants-in-atrial-fibrillation-patients-undergoing-elective-cardioversion
#10
Saga Itäinen, Mika Lehto, Tuija Vasankari, Pirjo Mustonen, Mervi Kotamäki, Anna Numminen, Heli Lahtela, Aissa Bah, Juha Hartikainen, Anna-Mari Hekkala, Juhani K E Airaksinen
Aims: Non-vitamin K antagonist oral anticoagulants (NOAC) have been shown to be safe and effective alternatives to warfarin for the prevention of thromboembolic complications in patients with non-valvular atrial fibrillation (AF). The aim of this study was to investigate the complications and the use of NOACs in AF patients undergoing elective cardioversion. Methods and results: This nationwide multicentre study included consecutive elective cardioversions in AF patients treated with NOACs between October 2011 and May 2016...
July 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016695/oral-anticoagulant-persistence-in-patients-with-non-valvular-atrial-fibrillation-a-cohort-study-using-primary-care-data-in-germany
#11
Shuk-Li Collings, Cinira Lefèvre, Michelle E Johnson, David Evans, Guido Hack, Gillian Stynes, Andrew Maguire
This study examined characteristics and treatment persistence among patients prescribed oral anticoagulants (OACs) for stroke prevention in non-valvular atrial fibrillation (NVAF). We identified 15,244 patients (51.8% male, 72.7% aged ≥70) with NVAF and no prior OAC therapy who were prescribed apixaban (n = 1,303), rivaroxaban (n = 5,742), dabigatran (n = 1,622) or vitamin-K antagonists (VKAs, n = 6,577) between 1-Dec-2012 and 31-Oct-2014 in German primary care (IMS® Disease Analyzer). We compared OAC persistence using Cox regression over patients' entire follow-up and using a data-driven time-partitioned approach (before/after 100 days) to handle non-proportional hazards...
2017: PloS One
https://www.readbyqxmd.com/read/28990089/kinin-b1-receptor-as-a-novel-prognostic-progression-biomarker-for-carotid-atherosclerotic-plaques
#12
Tiantian Liu, Hengfang Liu, Li Feng, Bo Xiao
Stroke caused by atherosclerosis remains a leading cause of morbidity and mortality worldwide, associated with carotid plaque rupture and inflammation progression. However, the inflammatory biomarkers which aid in predicting the future course of plaques are less detailed. The present study investigated the association between plaque vulnerable and inflammatory biomarkers using blood and plaque specimens. Carotid plaque specimens were obtained from 80 patients following stroke, 14 patients suffering from transient ischaemic attack and 17 asymptomatic patients that underwent carotid endarterectomy...
December 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28986404/predictors-of-successful-chronic-total-occlusion-percutaneous-coronary-interventions-a-systematic-review-and-meta-analysis
#13
Nelson Wang, Jordan Fulcher, Nishan Abeysuriya, Mark Adams, Sean Lal
OBJECTIVE: The aim of this study was to identify positive and negative predictors of technical and clinical success for percutaneous coronary intervention (PCI) of chronic total occlusions (CTO). METHODS: We conducted a systematic review and meta-analysis of studies published between 2000 and 2016 analysing rates of CTO PCI success with respect to demographic and angiographic characteristics. Crude ORs and 95% CIs for each predictor were calculated using a random effects model...
October 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28962101/perfusion-weighted-magnetic-resonance-imaging-in-the-assessment-of-haemodynamics-following-stent-angioplasty-in-patients-with-symptomatic-middle-cerebral-artery-plaque-stenosis-at-the-m1-segment
#14
Yun-Cai Ran, Ming Zhu, Yong Zhang, Teng-Fei Li, Jing-Liang Cheng
The most effective strategy to assess changes in the brain haemodynamics of stent angioplasty in patients with symptomatic ischemia of the M1 segment of the middle cerebral artery (MCA) remains unknown. The purpose of the present study was to use perfusion-weighted magnetic resonance imaging (PWI) to evaluate the effect of stent angioplasty in treating patients with symptomatic MCA plaque stenosis. Stent angioplasty was performed on 23 patients with reduplicative transient ischaemic attack who were refractory to medical therapy...
September 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28959496/cerebral-misery-perfusion-due-to-carotid-occlusive-disease
#15
REVIEW
Mohana Maddula, Nikola Sprigg, Philip M Bath, Sunil Munshi
PURPOSE: Cerebral misery perfusion (CMP) is a condition where cerebral autoregulatory capacity is exhausted, and cerebral blood supply in insufficient to meet metabolic demand. We present an educational review of this important condition, which has a range of clinical manifestations. METHOD: A non-systematic review of published literature was undertaken on CMP and major cerebral artery occlusive disease, using Pubmed and Sciencedirect. FINDINGS: Patients with CMP may present with strokes in watershed territories, collapses and transient ischaemic attacks or episodic movements associated with an orthostatic component...
June 2017: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/28959490/abcd-2-risk-score-does-not-predict-the-presence-of-cerebral-microemboli-in-patients-with-hyper-acute-symptomatic-critical-carotid-artery-stenosis
#16
Mahmud Saedon, Charles E Hutchinson, Christopher H E Imray, Donald R J Singer
INTRODUCTION: ABCD(2) risk score and cerebral microemboli detected by transcranial Doppler (TCD) have been separately shown to the predict risk of recurrent acute stroke. We studied whether ABCD(2) risk score predicts cerebral microemboli in patients with hyper-acute symptomatic carotid artery stenosis. PARTICIPANTS AND METHODS: We studied 206 patients presenting within 2 weeks of transient ischaemic attack or minor stroke and found to have critical carotid artery stenosis (≥50%)...
June 2017: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/28959486/chinese-atherosclerosis-risk-evaluation-care-ii-study-a-novel-cross-sectional-multicentre-study-of-the-prevalence-of-high-risk-atherosclerotic-carotid-plaque-in-chinese-patients-with-ischaemic-cerebrovascular-events-design-and-rationale
#17
Xihai Zhao, Rui Li, Daniel S Hippe, Thomas S Hatsukami, Chun Yuan
BACKGROUND: Carotid atherosclerotic plaque is identified as one of the main sources of ischaemic stroke. However, the prevalence of carotid high-risk atherosclerotic plaque in Chinese patients with ischaemic cerebrovascular events has been inconsistently reported and needs to be investigated in a large population. OBJECTIVES: The primary objective of CARE II study was to determine the prevalence and characteristics of high-risk features of atherosclerotic plaques in the carotid arteries in Chinese patients with recent ischaemic stroke or transient ischaemia attack (TIA)...
March 2017: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/28956476/a-study-of-the-relationship-between-the-quality-of-lifestyle-counselling-and-later-adherence-to-the-lifestyle-changes-based-on-patients-with-stroke-and-tia
#18
Anne Oikarinen, Janne Engblom, Helvi Kyngäs, Maria Kääriäinen
OBJECTIVE: To identify associations between lifestyle counselling quality and adherence to lifestyle changes during the 12-month period after discharge. SETTING: Neurology unit. SUBJECTS: Stroke and transient ischaemic attack (TIA) patients ( n = 98). DESIGN: Longitudinal explorative study that utilized data initially collected for quasi-experimental study. MAIN MEASURES: The exploratory measures of Counselling Quality were collected at the hospital on the day of discharge between January 2010 and October 2011, and the outcome measures of Adherence to Lifestyle Change and clinical values were collected 3, 6 and 12 months after discharge...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28939682/effects-of-pioglitazone-on-cognitive-function-in-patients-with-a-recent-ischaemic-stroke-or-tia-a-report-from-the-iris-trial
#19
Karen L Furie, Catherine M Viscoli, Mark Gorman, Gary A Ford, Lawrence H Young, Silvio E Inzucchi, Peter D Guarino, Anne M Lovejoy, Robin Conwit, David Tanne, Walter N Kernan
INTRODUCTION: Patients with cerebrovascular disease are at increased risk for cognitive dysfunction. Modification of vascular risk factors, including insulin resistance, could improve poststroke cognitive function. METHODS: In the Insulin Resistance Intervention after Stroke (IRIS) trial, patients with a recent ischaemic stroke or transient ischaemic attack (TIA) were randomised to pioglitazone (target 45 mg daily) or placebo. All patients were insulin resistant based on a Homeostasis Model Assessment-Insulin Resistance score >3...
September 22, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28939569/recording-a-diagnosis-of-stroke-transient-ischaemic-attack-or-myocardial-infarction-in-primary-healthcare-and-the-association-with-dispensation-of-secondary-preventive-medication-a-registry-based-prospective-cohort-study
#20
Cecilia Dahlgren, Lukas Geary, Jan Hasselström, Clas Rehnberg, Karin Schenck-Gustafsson, Per Wändell, Mia von Euler
OBJECTIVES: The aim of this study was to explore whether recording in primary care of a previously recorded hospital diagnosis was associated with increased patient utilisation of recommended medications. DESIGN: Registry-based prospective cohort study. SETTING AND PARTICIPANTS: 19 072 patients with a hospital discharge diagnosis of transient ischaemic attack (TIA), stroke or acute coronary syndrome from hospitals in Stockholm County 2010-2013 were included in the study...
September 21, 2017: BMJ Open
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