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One Health AND Antimicrobial resistance

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https://www.readbyqxmd.com/read/28730149/review-of-antibiotic-resistance-in-the-indian-ocean-commission-a-human-and-animal-health-issue
#1
REVIEW
Noellie Gay, Olivier Belmonte, Jean-Marc Collard, Mohamed Halifa, Mohammad Iqbal Issack, Saindou Mindjae, Philippe Palmyre, Abdul Aziz Ibrahim, Harena Rasamoelina, Loïc Flachet, Laurent Filleul, Eric Cardinale
Antimicrobial resistance (AMR) is a major threat to human, animal health, and environment worldwide. For human, transmission occurred through a variety of routes both in health-care settings and community. In animals, AMR was reported in livestock, pets, and wildlife; transmission of AMR can be zoonotic with the probably most important route being foodborne transmission. The Indian Ocean Commission (IOC), composed of Comoros, Madagascar, Mauritius, Reunion (France), and Seychelles recognized the surveillance of AMR in both animal and human as a main public health priority for the region...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28721477/imipenem-resistant-gram-negative-bacterial-isolates-carried-by-persons-upon-medical-examination-in-korea
#2
So Yeon Kim, Sang Yop Shin, Ji-Young Rhee, Kwan Soo Ko
Carbapenem-resistant Gram-negative bacteria (CR-GNB) have emerged and disseminated worldwide, become a great concern worldwide including Korea. The prevalence of fecal carriage of imipenem-resistant Gram-negative bacteria (IR-GNB) in persons in Korea was investigated. Stool samples were collected from 300 persons upon medical examination. Samples were screened for IR-GNB by using MacConkey agar with 2 μl/ml imipenem. Species were identified by 16S rRNA gene sequence analysis, and antimicrobial susceptibility was determined by the broth microdilution method...
July 18, 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/28716198/herd-specific-interventions-to-reduce-antimicrobial-usage-in-pig-production-without-jeopardising-technical-and-economic-performance
#3
L Collineau, C Rojo-Gimeno, A Léger, A Backhans, S Loesken, E Okholm Nielsen, M Postma, U Emanuelson, E Grosse Beilage, M Sjölund, E Wauters, K D C Stärk, J Dewulf, C Belloc, S Krebs
Pig farmers are strongly encouraged to reduce their antimicrobial usage in order to reduce the risk of antimicrobial resistance. Herd-level intervention is needed to achieve national and European reduction targets. Alternative, especially preventive measures, have to be implemented to reduce the need for antimicrobial treatments. However, little is known about the feasibility, effectiveness and return on investment of such measures. The objective of this study was to assess, across four countries, the technical and economic impact of herd-specific interventions aiming at reducing antimicrobial usage in pig production while implementing alternative measures...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28714488/nasal-carriage-rate-of-methicillin-resistant-staphylococcus-aureus-among-health-care-workers-at-a-tertiary-care-hospital-in-kathmandu-nepal
#4
S Khatri, N D Pant, R Bhandari, K L Shrestha, C D Shrestha, N Adhikari, A Poudel
BACKGROUND: Methicillin-resistant Staphylococcus aureus is one of the most common causes of nosocomial infections. Due to its multidrug resistant nature; infections due to Methicillin-resistant Staphylococcus aureus are often very difficult to treat. Colonized health care workers are the important sources of Methicillin-resistant Staphylococcus aureus. The objectives of this study were to determine the nasal carriage rate of Methicillin-resistant Staphylococcus aureus among health care workers at Kathmandu Medical College and Teaching Hospital, Nepal and to assess their antimicrobial susceptibility patterns...
January 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28712667/antibiotic-stewardship-in-low-and-middle-income-countries-same-but-different
#5
REVIEW
Janneke A Cox, Erika Vlieghe, Marc Mendelson, Heiman Wertheim, Linus Ndegwa, Maria Virginia Villegas, Ian Gould, Gabriel Levy Hara
BACKGROUND: Antibiotic resistance (ABR) is a quickly worsening problem worldwide, also in low-and middle-income countries (LMICs). Appropriate antibiotic use in humans and animals, i.e. antibiotic stewardship (ABS), is one of the corner stones of the World Health Organization's global action plan for ABR. Many LMICs are in the process of developing stewardship policies and programs. AIMS: We highlight the challenges for ABS initiatives in LMICs, give an outline of the (inter)national recommendations and demonstrate examples of effective, contextualised stewardship interventions...
July 13, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28711585/global-outbreak-of-severe-mycobacterium-chimaera-disease-after-cardiac-surgery-a-molecular-epidemiological-study
#6
Jakko van Ingen, Thomas A Kohl, Katharina Kranzer, Barbara Hasse, Peter M Keller, Anna Katarzyna Szafrańska, Doris Hillemann, Meera Chand, Peter Werner Schreiber, Rami Sommerstein, Christoph Berger, Michele Genoni, Christian Rüegg, Nicolas Troillet, Andreas F Widmer, Sören L Becker, Mathias Herrmann, Tim Eckmanns, Sebastian Haller, Christiane Höller, Sylvia B Debast, Maurice J Wolfhagen, Joost Hopman, Jan Kluytmans, Merel Langelaar, Daan W Notermans, Jaap Ten Oever, Peter van den Barselaar, Alexander B A Vonk, Margreet C Vos, Nada Ahmed, Timothy Brown, Derrick Crook, Theresa Lamagni, Nick Phin, E Grace Smith, Maria Zambon, Annerose Serr, Tim Götting, Winfried Ebner, Alexander Thürmer, Christian Utpatel, Cathrin Spröer, Boyke Bunk, Ulrich Nübel, Guido V Bloemberg, Erik C Böttger, Stefan Niemann, Dirk Wagner, Hugo Sax
BACKGROUND: Since 2013, over 100 cases of Mycobacterium chimaera prosthetic valve endocarditis and disseminated disease were notified in Europe and the USA, linked to contaminated heater-cooler units (HCUs) used during cardiac surgery. We did a molecular epidemiological investigation to establish the source of these patients' disease. METHODS: We included 24 M chimaera isolates from 21 cardiac surgery-related patients in Switzerland, Germany, the Netherlands, and the UK, 218 M chimaera isolates from various types of HCUs in hospitals, from LivaNova (formerly Sorin; London, UK) and Maquet (Rastatt, Germany) brand HCU production sites, and unrelated environmental sources and patients, as well as eight Mycobacterium intracellulare isolates...
July 12, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28706393/cotrimoxazole-a-wonder-drug-in-the-era-of-multiresistance-case-report-and-review-of-literature
#7
Priyam Batra, Vishant Deo, Purva Mathur, Amit Kumar Gupta
Antimicrobial resistance is one of the greatest threats to human health worldwide. The rate of development of newer antibiotics is much slower than the rate of development of antibiotic resistance. A survey reported that it takes 15 years and US$800 million (including preclinical and clinical costs) to bring a single drug to the market, whereas the reuse of the older drugs for antimicrobial use takes $17 million, thereby circumventing 40% of the overall cost. The first case is a patient with nosocomial pyrexia of unknown origin who was given treatment with tigecycline and cefepime/tazobactam but failed to respond to the same...
July 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28702307/childhood-pneumonia-and-meningitis-in-the-eastern-highlands-province-papua-new-guinea-in-the-era-of-conjugate-vaccines-study-methods-and-challenges
#8
Christopher C Blyth, Rebecca Ford, Joycelyn Sapura, Tonny Kumani, Geraldine Masiria, John Kave, Lapule Yuasi, Andrew Greenhill, Ilomo Hwaihwanje, Amanda Lang, Deborah Lehmann, William Pomat
BACKGROUND: Pneumonia and meningitis are common causes of severe childhood illness in Papua New Guinea (PNG). The etiology of both clinical conditions in PNG has not been recently assessed. Changes in lifestyle, provision and access to healthcare, antimicrobial utilization and resistance, and the national childhood vaccination schedule necessitate reassessment. METHODS: A prospective case-control study was undertaken, enrolling children <5 years of age to determine the contemporary etiology of clinically defined moderate or severe pneumonia or suspected meningitis...
2017: Pneumonia
https://www.readbyqxmd.com/read/28694537/survey-of-antimicrobial-stewardship-practices-in-public-hospitals-in-new-zealand-district-health-boards
#9
Sharon J Gardiner, Jane A Pryer, Eamon J Duffy
AIMS: To determine what antimicrobial stewardship (AMS) practices exist in New Zealand public hospitals. METHODS: A quantitative survey based on recommended components of hospital AMS programmes was sent to the 20 DHBs in June 2016. RESULTS: Ten of the 20 DHBs had an AMS committee, nine had dedicated AMS pharmacist full-time equivalents (FTEs) and eight had lead clinician FTEs. Only one DHB met FTE recommendations for AMS pharmacists and two for clinicians (0...
July 7, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28693504/prevalence-of-multi-drug-resistant-enteropathogenic-and-enteroinvasive-escherichia-coli-isolated-from-children-with-and-without-diarrhea-in-northeast-indian-population
#10
Karuppasamy Chellapandi, Tapan Kumar Dutta, Indu Sharma, Surajit De Mandal, Nachimuthu Senthil Kumar, Lalsanglura Ralte
BACKGROUND: Diarrheagenic Escherichia coli are associated with infantile diarrhea in the developing countries. The present study was conducted to determine the occurrence and antimicrobial resistance pattern of enteropathogenic and enteroinvasive E. coli associated with diarrhoea among the paediatric patients. METHODS: A total of 262 stool samples were collected from children with and without diarrhea from Mizoram, Northeast India. E. coli were isolated and subjected to multiplex PCR to detect virulent genes of EPEC (eaeA and bfpA) and EIEC (ial)...
July 11, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28690026/antimicrobial-peptides-as-potential-anti-biofilm-agents-against-multidrug-resistant-bacteria
#11
REVIEW
Pooi Yin Chung, Ramona Khanum
Bacterial resistance to commonly used drugs has become a global health problem, causing increased infection cases and mortality rate. One of the main virulence determinants in many bacterial infections is biofilm formation, which significantly increases bacterial resistance to antibiotics and innate host defence. In the search to address the chronic infections caused by biofilms, antimicrobial peptides (AMP) have been considered as potential alternative agents to conventional antibiotics. Although AMPs are commonly considered as the primitive mechanism of immunity and has been extensively studied in insects and non-vertebrate organisms, there is now increasing evidence that AMPs also play a crucial role in human immunity...
June 26, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28668688/massive-misuse-of-antibiotics-by-university-students-in-all-regions-of-china-implications-for-national-policy
#12
Xiaomin Wang, Dandan Peng, Weiyi Wang, Yannan Xu, Xudong Zhou, Therese Hesketh
Antimicrobial resistance (AMR) is one of the greatest threats to population health this century. The primary cause of AMR is antibiotic misuse, especially the routine use of antibiotics for self-limiting illnesses. The major aim of this study was to explore behaviours in relation to antibiotic use in university students across China. An electronic questionnaire was distributed at a major university in each of the six regions. A cluster random sampling method was adopted. Chi-square and logistic regression were used to assess the relationship between knowledge and behaviour...
June 28, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28664714/analysis-of-acinetobacter-baumannii-resistance-patterns-in-patients-with-chronic-obstructive-pulmonary-disease-copd-in-terms-of-choice-of-effective-empiric-antibiotic-therapy
#13
Aneta Grochowalska, Maria Kozioł-Montewka, Anna Sobieszczańska
<b>Introduction.</b> Multi-resistant Acinetobacter baumannii isolated from patients has become one of the most hazardous pathogens in health care settings. The aim of the study was to analyze pneumonia caused by Acinetobacter baumannii in patients hospitalized because of exacerbation of chronic obstructive pulmonary diseases (COPD), who were admitted to the Pulmonology Ward of the Masovian Specialistic Hospital in Radom (MSS). The incidence and drug sensitivity of these non-fermenting rods were evaluated, and compliance with antimicrobial procedure with the algorithm of the guidelines in applicable recommendations, was estimated...
June 12, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28659133/a-multicentre-double-blind-randomised-controlled-trial-evaluating-the-efficacy-of-daily-use-of-antibacterial-mouthwash-against-oropharyngeal-gonorrhoea-among-men-who-have-sex-with-men-the-omega-oral-mouthwash-use-to-eradicate-gonorrhoea-study-protocol
#14
Eric P F Chow, Sandra Walker, Jane S Hocking, Catriona S Bradshaw, Marcus Y Chen, Sepehr N Tabrizi, Benjamin P Howden, Matthew G Law, Kate Maddaford, Tim R H Read, David A Lewis, David M Whiley, Lei Zhang, Andrew E Grulich, John M Kaldor, Vincent J Cornelisse, Samuel Phillips, Basil Donovan, Anna M McNulty, David J Templeton, Norman Roth, Richard Moore, Christopher K Fairley
BACKGROUND: Gonorrhoea is one of the most common sexually transmissible infections in men who have sex with men (MSM). Gonorrhoea rates have increased substantially in recent years. There is concern that increasing gonorrhoea prevalence will increase the likelihood of worsening antibiotic resistance in Neisseria gonorrhoeae. A recent randomised controlled trial (RCT) demonstrated that a single-dose of mouthwash has an inhibitory effect against oropharyngeal gonorrhoea. We are conducting the first RCT to evaluate whether daily use of mouthwash could reduce the risk of acquiring oropharyngeal gonorrhoea...
June 28, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28657870/a-placebo-controlled-trial-of-antibiotics-for-smaller-skin-abscesses
#15
RANDOMIZED CONTROLLED TRIAL
Robert S Daum, Loren G Miller, Lilly Immergluck, Stephanie Fritz, C Buddy Creech, David Young, Neha Kumar, Michele Downing, Stephanie Pettibone, Rebecca Hoagland, Samantha J Eells, Mary G Boyle, Trisha Chan Parker, Henry F Chambers
BACKGROUND: Uncomplicated skin abscesses are common, yet the appropriate management of the condition in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA) is unclear. METHODS: We conducted a multicenter, prospective, double-blind trial involving outpatient adults and children. Patients were stratified according to the presence of a surgically drainable abscess, abscess size, the number of sites of skin infection, and the presence of nonpurulent cellulitis...
June 29, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28655298/assessment-of-staphylococcus-aureus-along-milk-value-chain-and-its-public-health-importance-in-sebeta-central-oromia-ethiopia
#16
Yodit Ayele, Fanta Desissa Gutema, Bedaso Mamo Edao, Robel Girma, Takele Beyene Tufa, Tariku Jibat Beyene, Fanos Tadesse, Mesula Geloye, Ashenafi Feyisa Beyi
BACKGROUND: Staphylococcus aureus is one of the leading causes of gastroenteritis acquired from contaminated foods such as milk and milk products. However, such information is limited in Ethiopia. A cross-sectional study was conducted to assess the contamination of milk with S. aureus and knowledge, attitudes and practices (KAP) of actors along the milk value chain in Sebeta, Central Oromia, Ethiopia. A total of 291 samples collected from dairy farms, milk collection centers (MCCs) and processing plant were examined using standard microbiological techniques...
June 27, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28650938/outbreak-caused-by-escherichia-coli-o18-k1-h7-sequence-type-95-in-a-neonatal-intensive-care-unit-in-barcelona-spain
#17
Emma Sáez-López, Jordi Bosch, Maria Dolors Salvia, Dietmar Fernández-Orth, Virginio Cepas, Mario Ferrer-Navarro, Josep Figueras-Aloy, Jordi Vila, Sara M Soto
BACKGROUND: Escherichia coli is one of the most frequent causes of late-onset neonatal sepsis. The aim of this study was to characterize an outbreak of neonatal sepsis occurring in the neonatal intensive care unit (NICU) of the Hospital Clinic of Barcelona from April to August 2013. METHODS: After presentation of the index case, all E. coli isolates from previously hospitalized neonates, health care workers, and neonates admitted to the NICU from April to October 2013 were tested for K1 antigen positivity and epidemiologically compared by pulse-field gel electrophoresis...
June 23, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28642992/plasmid-mediated-quinolone-resistance-pmqr-genes-and-class-1-integrons-in-quinolone-resistant-marine-bacteria-and-clinical-isolates-of-escherichia-coli-from-an-aquacultural-area
#18
Alexandra Tomova, Larisa Ivanova, Alejandro H Buschmann, Henry P Godfrey, Felipe C Cabello
Antimicrobial usage in aquaculture selects for antimicrobial-resistant microorganisms in the marine environment. The relevance of this selection to terrestrial animal and human health is unclear. Quinolone-resistance genes qnrA, qnrB, and qnrS were chromosomally located in four randomly chosen quinolone-resistant marine bacteria isolated from an aquacultural area with heavy quinolone usage. In quinolone-resistant uropathogenic clinical isolates of Escherichia coli from a coastal area bordering the same aquacultural region, qnrA was chromosomally located in two E...
June 23, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28638874/the-use-of-plants-to-protect-plants-and-food-against-fungal-pathogens-a-review
#19
D S S Shuping, J N Eloff
BACKGROUND: Plant fungal pathogens play a crucial role in the profitability, quality and quantity of plant production. These phytopathogens are persistent in avoiding plant defences causing diseases and quality losses around the world that amount to billions of US dollars annually. To control the scourge of plant fungal diseases, farmers have used fungicides to manage the damage of plant pathogenic fungi. Drawbacks such as development of resistance and environmental toxicity associated with these chemicals have motivated researchers and cultivators to investigate other possibilities...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28631121/-prudent-use-of-antimicrobial-prophylaxis-prevention-of-increasing-antibiotic-resistance
#20
REVIEW
C Hein, A Pilatz, F M E Wagenlehner
BACKGROUND: The use of peri-operative antimicrobial prophylaxis during urological procedures to prevent postoperative complications is very common. OBJECTIVES: What kind of recommendations for reasonable use of peri-operative antimicrobial prophylaxis during urological procedures to prevent increasing antibiotic resistance and postoperative complications exist? METHODS: Review of evidence-based recommendations from literature and current Guidelines of the EAU...
June 19, 2017: Der Urologe. Ausg. A
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