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One Health AND Antimicrobial resistance

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https://www.readbyqxmd.com/read/28079629/duration-of-pneumonia-therapy-and-the-role-of-biomarkers
#1
Katerina Kaziani, Adamantia Sotiriou, George Dimopoulos
PURPOSE OF REVIEW: Increasing antimicrobial resistance is a worldwide phenomenon that is threatening public health. Lower respiratory infections are one of the leading causes of morbidity that contribute to antibiotic consumption and thus the emergence of multidrug-resistant microbial strains. The goal of shortening antibiotic regimens' duration in common bacterial infections has been prioritized by antimicrobial stewardship programs as an action against this problem. RECENT FINDINGS: Data coming from randomized controlled trials, meta-analyses, and systematic reviews support the shortening of antimicrobial regimens in community-acquired, hospital-acquired, and ventilator-associated pneumonia...
January 12, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28065568/synthesis-and-antimicrobial-studies-of-novel-derivatives-of-4-4-formyl-3-phenyl-1h-pyrazol-1-yl-benzoic-acid-as-potent-anti-acinetobacter-baumannii-agents
#2
Devin Allison, Evan Delancey, Hunter Ramey, Conrad Williams, Zakeyah Ali Alsharif, Hessa Al-Khattabi, Allyn Ontko, David Gilmore, Mohammad A Alam
Microbial resistance to antibiotics is a global concern. The World Health Organization (WHO) has identified antimicrobial resistance as one the three greatest threats for human beings in the 21st century. Without urgent and coordinated action, the world is moving toward a post-antibiotic era, in which normal infections or minor injuries may become fatal. In an effort to find new agents, we report the synthesis and antimicrobial activities of 40 novel 1,3-diphenyl pyrazole derivatives. These compounds have shown zones of growth inhibition up to 85mm against Acinetobacter baumannii...
December 29, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28065331/antimicrobial-stewardship-in-kansas-results-from-a-statewide-survey
#3
Carrie Poteete, Joseph M Scaletta
BACKGROUND: The availability of effective antibiotics is considered one of the most important developments in medicine. However, many organisms that were once susceptible to common antibiotics are becoming resistant. Antimicrobial stewardship programs (ASPs) are considered to be vital for combating the emergence of resistance. To understand current antimicrobial stewardship practices in Kansas, the authors designed a 36-question survey. Results of this survey will be used to develop a coordinated, public health strategy for improving current practices...
January 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28053586/comparison-of-phenotypic-and-pcr-methods-for-detection-of-carbapenemases-production-by-enterobacteriaceae
#4
Maryam AlTamimi, Ali AlSalamah, Manal AlKhulaifi, Hisham AlAjlan
Dissemination of carbapenem resistance via Enterobacteriaceae, particularly among Klebsiella pneumoniae and Escherichia coli, is a major public health concern. Rapid methods for determining antimicrobial susceptibility are important to ensure adequate and appropriate use of antimicrobial agents and to limit the spread of these bacteria. In the current study, we compared the rapidity, sensitivity and specificity of traditional methods and molecular-based Xpert Carba-R PCR assay to identify sixty isolates, (26 E...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28040165/antimicrobial-susceptibility-and-genetic-characterization-of-escherichia-coli-recovered-from-frozen-game-meat
#5
Rafael H Mateus-Vargas, Viktoria Atanassova, Felix Reich, Günter Klein
The increasing number of antimicrobial resistant Enterobacteriaceae both in veterinary and human medicine, the dissemination of these bacteria in several environments and their possible repercussions on human health is causing concern. Game meat is usually seen as free of antimicrobial resistant bacteria. The objective of this study was to evaluate the current antimicrobial susceptibility status in generic Escherichia coli isolated from packed frozen game meat from a game handling establishment in Germany. A total of 229 E...
May 2017: Food Microbiology
https://www.readbyqxmd.com/read/28036310/comparison-of-hrm-analysis-and-three-rep-pcr-genomic-fingerprint-methods-for-rapid-typing-of-mrsa-at-a-brazilian-hospital
#6
Giovana Carolina Bodnar, Heloísa Moreira Martins, Caio Ferreira De Oliveira, Alexandre Tadachi Morey, Eliandro Reis Tavares, Juscélio Donizete Cardoso, Marcia Regina Eches Perugini, Lucy Megumi Yamauchi Lioni, Sueli Fumie Yamada-Ogatta, Renata Katsuko Takayama Kobayashi, Gerson Nakazato
INTRODUCTION: Infections caused by multidrug-resistant bacteria are increasingly common and represent a serious problem for public health. Staphylococcus aureus is one of the major agents of infections, and methicillin-resistant S. aureus (MRSA) has spread worldwide. The aim of this study was to phenotypically and genotypically characterize 55 MRSAs isolated in the University Hospital of Londrina, Paraná, Brazil, during 2010. METHODOLOGY: Bacterial isolates were characterized based on their antimicrobial susceptibility profile, biofilm production capacity, and staphylococcal chromosome cassette mec (SCCmec) type...
December 30, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28007546/biopolymeric-self-assembled-nanoparticles-for-enhanced-antibacterial-activity-of-ag-based-compounds
#7
Dhanya Dhanyalayam, Luca Scrivano, Ortensia Ilaria Parisi, Maria Stefania Sinicropi, Antonietta Fazio, Carmela Saturnino, Maria Rosaria Plutino, Francesca Di Cristo, Francesco Puoci, Anna Rita Cappello, Pasquale Longo
Microbial infections still remain one of the main issues for human health. The rapid development of resistance towards the most common antimicrobial drugs in bacteria represents today a challenge in the infections management. In the present work we have investigated the antibacterial activity of a group of compounds, namely silver N-heterocyclic carbene complexes, against a broad spectrum of bacteria. For the most promising compound, a biopolymeric nanocarrier has been developed, in order to potentiate the metal complex activity against both Gram +ve and Gram -ve...
December 19, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27999044/influence-of-antimicrobial-susceptibility-reporting-on-junior-doctors-decision-to-prescribe-antimicrobials-inappropriately
#8
Lito E Papanicolas, Renjy Nelson, Morgyn S Warner
OBJECTIVES: Inappropriate antimicrobial use drives antimicrobial resistance and is a global public health problem. This study examined whether withholding antimicrobial susceptibilities in combination with interpretive comments on microbiological reports influenced the decision to inappropriately prescribe antibiotics in a controlled survey. METHODS: Seventy junior doctors attending educational sessions were given one of two surveys describing four clinical case vignettes (scenarios) in which antimicrobial treatment was not indicated...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27976593/antimicrobial-resistance-in-enterococcus-strains-isolated-from-healthy-domestic-dogs
#9
Fabrizio Bertelloni, Claudia Salvadori, Giulia Lotti, Domenico Cerri, Valentina Virginia Ebani
Enterococci are opportunistic bacteria that cause severe infections in animals and humans, capable to acquire, express, and transfer antimicrobial resistance. Susceptibility to 21 antimicrobial agents was tested by the disk diffusion method in 222 Enterococcus spp. strains isolated from the fecal samples of 287 healthy domestic dogs. Vancomycin and ampicillin minimum inhibitory concentrations (MICs) and high-level aminoglycoside resistance (HLAR) tests were also performed. Isolates showed resistance mainly to streptomycin (88...
December 15, 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27968914/massive-misuse-of-antibiotics-by-university-students-in-china-a-cross-sectional-survey
#10
Xiao-Min Wang, Xu-Dong Zhou, Therese Hesketh
BACKGROUND: Antimicrobial resistance is one of the greatest threats to global population health this century, and is a major contributor to rising healthcare costs worldwide. The primary cause of this resistance is antibiotic misuse, especially routine inappropriate use of antibiotics for self-limiting illnesses. In China, over prescribing of antibiotics is pervasive leading to very high and increasing rates of antimicrobial resistance in both hospital-acquired and community-acquired infections...
October 2016: Lancet
https://www.readbyqxmd.com/read/27942743/reduction-of-antimicrobial-use-and-resistance-needs-sectoral-collaborations-with-a-one-health-approach-perspectives-from-asia
#11
EDITORIAL
Hung Nguyen-Viet, Suwit Chotinun, Esther Schelling, Winda Widyastuti, Nguyen Viet Khong, Manish Kakkar, Arlyne Beeche, Fang Jing, Boualam Khamlome, Sothyra Tum, Wiku Adisasmito
No abstract text is available yet for this article.
December 9, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27942365/isolation-antimicrobial-susceptibility-profile-and-detection-of-sul1-blatem-and-blashv-in-amoxicillin-clavulanate-resistant-bacteria-isolated-from-retail-sausages-in-kampar-malaysia
#12
Lih-Shin Tew, Li-Yen She, Choy-Hoong Chew
BACKGROUND: Due to the overuse of antibiotics in livestock as a growth-promoting agent, the emergence of multi-antibiotic resistant bacteria is becoming a concern. OBJECTIVES: In this study, we aimed to detect the presence and discover the molecular determinants of foodborne bacteria in retail sausages resistant towards the antibacterial agent amoxicillin-clavulanate. METHODS: Two grams of sausages were chopped into small pieces and transferred into sterile Luria-Bertani (LB) enrichment broths overnight before they were plated on MacConkey agar petri dishes...
October 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27936204/serotypes-and-antimicrobial-resistance-in-salmonella-enterica-recovered-from-clinical-samples-from-cattle-and-swine-in-minnesota-2006-to-2015
#13
Samuel Hong, Albert Rovira, Peter Davies, Christina Ahlstrom, Petra Muellner, Aaron Rendahl, Karen Olsen, Jeff B Bender, Scott Wells, Andres Perez, Julio Alvarez
Salmonellosis remains one of the leading causes of foodborne disease worldwide despite preventive efforts at various stages of the food production chain. The emergence of multi-drug resistant (MDR) non-typhoidal Salmonella enterica represents an additional challenge for public health authorities. Food animals are considered a major reservoir and potential source of foodborne salmonellosis; thus, monitoring of Salmonella strains in livestock may help to detect emergence of new serotypes/MDR phenotypes and to gain a better understanding of Salmonella epidemiology...
2016: PloS One
https://www.readbyqxmd.com/read/27927087/multidrug-resistant-enterobacteriaceae-in-new-zealand-a-current-perspective
#14
L J Toombs-Ruane, J Benschop, S Burgess, P Priest, D R Murdoch, N P French
In this article we review mechanisms and potential transmission pathways of multidrug resistance in Enterobacteriaceae, with an emphasis on extended spectrum β-lactamase (ESBL)-production. This provides background to better understand challenges presented by this important group of antimicrobial resistant bacteria, and inform measures aimed at prevention and control of antimicrobial resistance in general. Humans and animals interact at various levels; household pets cohabit with humans, and other animals interact with people through direct contact, as well as through the food chain and the environment...
December 7, 2016: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/27924169/hospital-acquired-infections-after-cardiac-surgery-and-current-physician-practices-a-retrospective-cohort-study
#15
Scott O'Keefe, Kenneth Williams, Jean-Francois Legare
BACKGROUND: The management of hospital-acquired infections (HAIs) with respect to physician practices remains largely unexplored despite increasing efforts to standardize care. In the present study, we report findings from a 2-month audit of all patients that have undergone cardiac surgery at a large referral center in Atlantic Canada. METHODS: All patients who underwent cardiac surgical procedures during May and June 2013 at the Queen Elizabeth II Health Sciences Center in Halifax, Nova Scotia were identified...
January 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27922763/antimicrobial-resistance-in-nontyphoidal-salmonella-isolated-from-human-and-poultry-related-samples-in-brazil-20-year-meta-analysis
#16
Daiane Voss-Rech, Luciana Potter, Clarissa Silveira Luiz Vaz, Daniela Isabel Brayer Pereira, Luís Antonio Sangioni, Águeda Castagna Vargas, Sônia de Avila Botton
Nontyphoidal Salmonella are one of the leading causes of foodborne diseases in the world. As poultry products are recognized as main sources of human salmonellosis, nontyphoidal Salmonella control has become a global issue for the poultry industry. The increasing antimicrobial resistance in poultry-related nontyphoidal Salmonella serovars is a global matter of concern. By monitoring the evolution of antimicrobial resistance, alternative treatments can be identified and possible restrictions in the treatment of systemic human salmonellosis foreseen...
December 6, 2016: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/27919287/chemical-profiling-antimicrobial-and-insecticidal-evaluations-of-polygonum-hydropiper-l
#17
Muhammad Ayaz, Muhammad Junaid, Farhat Ullah, Abdul Sadiq, Muhammad Ovais, Waqar Ahmad, Sajjad Ahmad, Anwar Zeb
BACKGROUND: The emergence of multidrug resistant (MDR) pathogens is of great concern to the global health community. Our ability to effectively treat diseases is based on the discovery of potent drugs for the treatment of these challenging diseases. Traditional medicines are one of the major sources for the discovery of safe, effective and economical drug candidates. In order to validate its antibacterial, antifungal and insecticidal potentials with respect to traditional uses, we have screened for the first time Polygonum hydropiper against pathogenic bacterial, fungal strains and a variety of insects...
December 5, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27918888/online-continuing-interprofessional-education-on-hospital-acquired-infections-for-latin-america
#18
Julio C Medina-Presentado, Alvaro Margolis, Lucia Teixeira, L Lorier, Ana C Gales, Graciela Pérez Sartori, Maura S Oliveira, Verónica Seija, Daniela Paciel, Rafael Vignoli, Silvia Guerra, Henry Albornoz, Zaida Arteta, Antonio Lopez-Arredondo, Sofía García
INTRODUCTION: Latin America is a large and diverse region, comprising more than 600 million inhabitants and one million physicians in over 20 countries. Resistance to antibacterial drugs is particularly important in the region. This paper describes the design, implementation and results of an international bi-lingual (Spanish and Portuguese) online continuing interprofessional interactive educational program on hospital-acquired infections and antimicrobial resistance for Latin America, supported by the American Society for Microbiology...
December 2, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27908581/sonodynamic-inactivation-of-gram-positive-and-gram-negative-bacteria-using-a-rose-bengal-antimicrobial-peptide-conjugate
#19
David Costley, Heather Nesbitt, Nigel Ternan, James Dooley, Ying-Ying Huang, Michael R Hamblin, Anthony P McHale, John F Callan
Combating antimicrobial resistance is one of the most serious public health challenges facing society today. The development of new antibiotics or alternative techniques that can help combat antimicrobial resistance is being prioritised by many governments and stakeholders across the globe. Antimicrobial photodynamic therapy is one such technique that has received considerable attention but is limited by the inability of light to penetrate through human tissue, reducing its effectiveness when used to treat deep-seated infections...
January 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27906121/one-health-training-and-research-activities-in-western-europe
#20
REVIEW
Reina Sikkema, Marion Koopmans
INTRODUCTION: The increase in emerging human infectious diseases that have a zoonotic origin and the increasing resistance of microorganisms to antimicrobial drugs have shown the need for collaborations between the human, animal and environmental health sectors. The One Health concept increasingly receives recognition from policy makers and researchers all over the world. This overview compiled research and education activities in the area of One Health in Western Europe (Austria, Belgium, France, Germany, Italy, Iceland, Ireland, Liechtenstein, Luxembourg, Monaco, the Netherlands, Portugal, Scandinavia, Spain, Switzerland, and the United Kingdom (UK), with a focus on infectious diseases...
2016: Infection Ecology & Epidemiology
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