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Pre operative anaemia

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https://www.readbyqxmd.com/read/27837236/effect-of-pre-operative-anaemia-on-post-operative-complications-in-low-resource-settings
#1
Michelle C White, Lydia Longstaff, Peggy S Lai
BACKGROUND: In high-resource settings, even mild anaemia is associated with an increased risk of post-operative complications. Whether this is true in low-resource settings is unclear. We aimed to evaluate the effect of anaemia on surgical outcomes in the Republic of Congo and Madagascar. METHOD: It is a retrospective chart review of 2064 non-pregnant patients undergoing elective surgery with Mercy Ships. Logistic regression was used to determine the association between pre-operative anaemia and pre-defined surgical complications, adjusted for age, gender, surgical specialty, and country...
November 11, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27721683/outcome-of-laparotomy-for-peritonitis-in-302-consecutive-patients-in-ibadan-nigeria
#2
O O Ayandipo, O O Afuwape, D O Irabor, A I Abdurrazzaaq, N A Nwafulume
BACKGROUND: Peritonitis is a life-threatening condition and requires urgent surgical management. Despite improvements in the care of patients with peritonitis, its management is still challenging and associated with significant morbidity and mortality. The aim of this study was to determine factors influencing the outcome in patients managed for peritonitis in a tertiary health institution in Nigeria. METHOD: A retrospective study involving 302 patients managed for peritonitis over a 3- year period...
June 2016: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/27704535/the-association-between-pre-operative-variables-including-blood-pressure-and-postoperative-kidney-function
#3
S M Kendale, P N Lapis, S M Melhem, J D Blitz
We used multivariate analyses to assess the association of pre-operative variables with kidney function in 41,523 adults after scheduled surgery in a single large academic hospital. Eight variables were independently associated with a reduction in postoperative estimated glomerular filtration rate: pre-operative renal function; age; ASA physical status; cardiac failure; anaemia; cancer; type of surgery; and the lowest quartile of pre-operative mean arterial blood pressure (< 71 mmHg). The estimated glomerular filtration rate fell by a mean (95% CI) of 2...
December 2016: Anaesthesia
https://www.readbyqxmd.com/read/27516193/could-the-erythrocyte-indices-or-serum-ferritin-predict-the-therapeutic-response-to-a-trial-with-oral-iron-during-pregnancy-results-from-the-accuracy-study-for-maternal-anaemia-diagnosis-ama
#4
Cristiane Campello Bresani Salvi, Maria Cynthia Braga, José Natal Figueirôa, Malaquias Batista Filho
BACKGROUND: Treatment of maternal iron-deficiency anaemia can reduce risks of prematurity and low birth weight; hence a reliable diagnosis of maternal iron needs is critical. However, erythrocyte indices and serum ferritin have shown a weak correlation with iron status during pregnancy. This study verified the accuracy of those tests to predict the responsiveness to a therapeutic test with oral iron as reference standard for iron deficiency in pregnant women. METHODS: A prospective diagnostic study phase 3 was conducted in a single prenatal care center in Northeast Brazil...
2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27483483/intravenous-iron-supplementation-with-intra-articular-administration-of-tranexamic-acid-reduces-the-rate-of-allogeneic-transfusions-after-simultaneous-bilateral-total-knee-arthroplasty
#5
Dong Won Suh, Seung-Beom Han, Jong-Hoon Park, Kuhoang Cheong, Bong Soo Kyung
BACKGROUND: Peri-operative intravenous administration of iron supplementation seems a good option to reduce allogeneic blood transfusion in major orthopaedic surgery. However, its efficacy in simultaneous bilateral total knee arthroplasty has not been studied. MATERIAL AND METHODS: From December 2014 to May 2015, a total of 72 consecutive patients underwent simultaneous bilateral total knee arthroplasty and received peri-operative intravenous iron supplementation (iron isomaltoside 1000: 600 mg pre-operatively and 400 mg 1 week post-operatively) and intra-articular tranexamic acid (2 g in 20 mL saline at the end of surgery), and were managed with a restrictive transfusion trigger (haemoglobin <7 g/dL)...
July 22, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27396803/preparing-the-patient-for-surgery-to-improve-outcomes
#6
REVIEW
Denny Z H Levett, Mark Edwards, Mike Grocott, Monty Mythen
The time between contemplation of surgery and the procedure offers a window of opportunity to optimize patients' nutritional, functional and psychological state prior to surgery. Traditionally, preoperative pathways have focused on the underlying disease process and 'fitness for surgery' with physical pre-assessment and risk counselling late in the pathway when little time is available to intervene. With an increasingly elderly and co-morbid surgical population, early physiological assessment and multidisciplinary collaborative decision-making is increasingly important...
June 2016: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/27235526/the-influence-of-a-history-of-clinical-depression-on-peri-operative-outcomes-in-elective-total-shoulder-arthroplasty-a-ten-year-national-analysis
#7
B Mollon, S A Mahure, D Y Ding, J D Zuckerman, Y W Kwon
AIMS: Depression can significantly affect quality of life and is associated with higher rates of medical comorbidities and increased mortality following surgery. Although depression has been linked to poorer outcomes following orthopaedic trauma, total joint arthroplasty and spinal surgery, we wished to examine the impact of depression in elective total shoulder arthroplasty (TSA) as this has not been previously explored. PATIENTS AND METHODS: The United States Nationwide Inpatient Sample (NIS) was used to identify patients undergoing elective TSA over a ten-year period...
June 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27141111/a-retrospective-analysis-of-massive-blood-transfusion-and-post-operative-complications-in-patients-undergoing-supra-major-orthopaedic-oncosurgeries
#8
Ankit Gupta, Atul Kulkarni
BACKGROUND AND AIMS: Anaesthetic management of patients undergoing supra-major orthopaedic oncosurgeries is challenging. We wanted to evaluate the effects of pre-operative co-morbid conditions, intraoperative blood loss and transfusion, haemodynamic instability on post-operative complications and hospital outcomes in patients after such surgeries. METHODS: We collected data from the patient files, anaesthesia records and the electronic medical records about pre-operative morbidities, intraoperative management, complications, blood loss, fluid therapy and blood products transfused...
April 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27037431/the-pre-operative-levels-of-haemoglobin-in-the-blood-can-be-used-to-predict-the-risk-of-allogenic-blood-transfusion-after-total-knee-arthroplasty
#9
J F Maempel, N R Wickramasinghe, N D Clement, I J Brenkel, P J Walmsley
AIMS: The pre-operative level of haemoglobin is the strongest predictor of the peri-operative requirement for blood transfusion after total knee arthroplasty (TKA). There are, however, no studies reporting a value that could be considered to be appropriate pre-operatively. This study aimed to identify threshold pre-operative levels of haemoglobin that would predict the requirement for blood transfusion in patients who undergo TKA. PATIENTS AND METHODS: Analysis of receiver operator characteristic (ROC) curves of 2284 consecutive patients undergoing unilateral TKA was used to determine gender specific thresholds predicting peri-operative transfusion with the highest combined sensitivity and specificity (area under ROC curve 0...
April 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27020662/determinants-of-peri-operative-blood-transfusion-in-a-contemporary-series-of-open-prostatectomy-for-benign-prostate-hyperplasia
#10
Mathew Y Kyei, George O Klufio, James E Mensah, Samuel Gepi-Attee, Kwabena Ampadu, Bernard Toboh, Edward D Yeboah
BACKGROUND: The objective of this study was to determine the factors responsible for peri-operative blood transfusion in a contemporary series of open prostatectomy for benign prostate hyperplasia and thus offer a guide for blood product management for the procedure. METHODS: This was a prospective study of 200 consecutive patients who underwent open prostatectomy for BPH from January 2010 to September 2013 at the Korle Bu Teaching Hospital, Accra. The data analyzed included the pre-operative blood haemoglobin level (Hb), presence of co-morbidities, the case type, indication for the surgery, ASA score, anaesthetic method used, systolic blood pressure, status of the operating surgeon, duration of surgery and the operative prostate weight...
2016: BMC Urology
https://www.readbyqxmd.com/read/26993159/the-incidence-and-importance-of-anaemia-in-patients-undergoing-cardiac-surgery-in-the-uk-the-first-association-of-cardiothoracic-anaesthetists-national-audit
#11
A A Klein, T J Collier, M S Brar, C Evans, G Hallward, S N Fletcher, T Richards
The importance and variability of pre-operative anaemia in cardiac surgical patients across the UK is not known, and there is debate about its association with patient outcomes. The Association of Cardiothoracic Anaesthetists carried out its first national audit on anaemia and transfusion, and analysed data from 19,033 patients operated on in 12 cardiac surgical centres between 2010 and 2012; 5895 (31%) had pre-operative anaemia. Centre-specific prevalence of anaemia varied from 23% to 45%; anaemia was associated with older patients, diabetes and surgical risk (EuroSCORE)...
June 2016: Anaesthesia
https://www.readbyqxmd.com/read/26908243/are-routine-blood-group-and-save-samples-needed-for-laparoscopic-day-case-surgery
#12
Peter M Thomson, Jack Ross, Samrat Mukherjee, Borzoueh Mohammadi
BACKGROUND: Common day case laparoscopic procedures are usually safe, with low rates of bleeding complications. At our trust, most patients undergo pre-operative group and save (G&S) for these procedures, at a cost of £18.39 per sample excluding laboratory staffing costs. Our aim was to assess if routine G&S is indicated. METHODS: We performed a retrospective review of all patients who underwent laparoscopic cholecystectomy (LC), laparoscopic inguinal hernia repair (LIH) and diagnostic laparoscopy (DL) in our institution between April 2012 and March 2014...
June 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/26878537/hip-fragility-fractures-anaemia-calcium-and-vitamin-d-supplementation
#13
Iqra Khan, Ambreen Jawaid, Khabir Ahmad, Shahryar Noordin
OBJECTIVE: To assess the burden of anaemia and osteoporosis in hip fracture patients, to determine the rate of blood transfusion per-operatively, to assess the use of calcium and vitamin D supplements and the use of anti-osteoporotic medications postoperatively. METHODS: A retrospective study was conducted at Aga Khan University and Hospital (AKUH) between June 2009 and May 2011, and comprised record of patients treated for intertrochanteric and femur neck fractures...
November 2015: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26694949/iron-therapy-for-pre-operative-anaemia
#14
REVIEW
Oliver Ng, Barrie D Keeler, Amitabh Mishra, Alastair Simpson, Keith Neal, Matthew J Brookes, Austin G Acheson
BACKGROUND: Pre-operative anaemia is common and occurs in up to 76% of patients. It is associated with increased peri-operative allogeneic blood transfusions, longer hospital lengths of stay and increased morbidity and mortality. Iron deficiency is one of the most common causes of this anaemia. Oral iron therapy has traditionally been used to treat anaemia but newer, safer parenteral iron preparations have been shown to be more effective in other conditions such as inflammatory bowel disease, chronic heart failure and post-partum haemorrhage...
December 22, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26621400/prevention-of-post-operative-anaemia-in-hip-and-knee-arthroplasty-a-systematic-review
#15
REVIEW
Nissa Khan, Anders Troelsen, Henrik Husted
INTRODUCTION: Patient blood management strategies for total hip and knee arthroplasty are controversial. They range from pre-operative haemoglobin optimisation to intra- and post-operative interventions. The aim of this study was to assess the various treatment modalities with respect to blood loss, haemoglobin levels and blood transfusions. METHODS: The analysis was based on the principles of a systematic review. The literature was searched in PubMed for the period from 2004 to November 2014...
December 2015: Danish Medical Journal
https://www.readbyqxmd.com/read/26620143/pre-operative-haematological-assessment-in-patients-scheduled-for-major-surgery
#16
REVIEW
M Muñoz, S Gómez-Ramírez, S Kozek-Langeneker
Peri-operative anaemia, blood loss and allogeneic blood transfusion are associated with increased postoperative morbidity and mortality, and prolonged hospital stay. A multidisciplinary, multimodal, individualised strategy, collectively termed 'patient blood management', may reduce or eliminate allogeneic blood transfusion and improve outcomes. This approach has three objectives: the detection and treatment of peri-operative anaemia; the reduction of peri-operative bleeding and coagulopathy; and harnessing and optimising the physiological tolerance of anaemia...
January 2016: Anaesthesia
https://www.readbyqxmd.com/read/26578732/pre-treatment-lymphocytopaenia-is-an-adverse-prognostic-biomarker-in-muscle-invasive-and-advanced-bladder-cancer
#17
N Joseph, S J Dovedi, C Thompson, J Lyons, J Kennedy, T Elliott, C M West, A Choudhury
BACKGROUND: Pre-treatment lymphocytopaenia may result from cytokines secreted by the tumour microenvironment in association with aggressive tumour biology. We sought to establish the prognostic significance of lymphocytopaenia in muscle-invasive and advanced bladder cancer. PATIENTS AND METHODS: Seventy-four patients with muscle-invasive bladder cancer treated with radical chemoradiotherapy and 131 patients with advanced bladder cancer treated with palliative chemotherapy were included in the study...
February 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/26568770/intravenous-tranexamic-acid-as-an-adjunct-haemostat-to-ornipressin-during-open-myomectomy-a-randomized-double-blind-placebo-controlled-trial
#18
Sammy Ngichabe, Timona Obura, William Stones
BACKGROUND: Myomectomy is a surgical technique used for removal of uterine fibroids and historically hysterectomy has represented the mainstay of treatment. The options of conservative surgical approaches mainly aim at retention of fertility but have to be balanced against potential risks such as haemorrhage; blood loss at myomectomy still remains troublesome with use of various pharmacologic agents yielding inconclusive results. This trial aimed to explore the benefit of combining ornipressin and tranexamic acid during open myomectomy...
2015: Annals of Surgical Innovation and Research
https://www.readbyqxmd.com/read/26524217/anaemia-in-elective-orthopaedic-surgery-royal-adelaide-hospital-australia
#19
B Kearney, J To, K Southam, D Howie, B To
BACKGROUND: An anaemia clinic was established to improve the preoperative management of elective orthopaedic patients scheduled for arthroplasty. This paper is a report on the first 100 patients assessed. AIM: To assess the incidence and causes of anaemia in patients on a waiting list for elective arthroplasty in a public hospital and to assess the impact of anaemia detection in this patient population. METHODS: Patients attending an Anaemia Clinic for elective orthopaedic surgical patients, during March 2010 to June 2013 were studied...
January 2016: Internal Medicine Journal
https://www.readbyqxmd.com/read/26262699/-pre-operative-iron-deficiency-in-bariatric-surgery-diagnosis-and-treatment
#20
Angela María Magali Sanchez, Natalia Pampillón, Mariela Abaurre, Pablo Esteban Omelanczuk
INTRODUCTION: chronic inflammation induced by obesity alters iron homeostasis leading to mild /moderate iron deficiency and anaemia. Between 14% and 43% of patients may suffer from iron deficiency without anaemia before surgery. The management of peri-operative iron deficiency improves patient outcome and quality of life. Under certain circumstances intravenous (IV) iron must be considered. IV iron (which may avoid iron blockage in enterocytes and macrophages) has turned out to be a safe and efficient alternative...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
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