Gloria Solano-Aguilar, Jonathan Shao, Joseph Urban, Sukla Lakshman, Saebyeol Jang, Victoria Lozano, Masoumeh Sikaroodi, Richi Gupta, Patrick Gillevet, Aleksey Molokin, Bryan Vinyard, Michael Humphrys, Monika Proszkowiec-Weglarz, Ethiopia Beshah, Stefania Lamon-Fava, Maura Walker, Nirupa Matthan, Alice Lichtenstein
Objectives: To determine the impact of two isocaloric diets containing (38% ,15% and 47% energy from fat, protein and carbohydrate, respectively): Western diet (WD) rich in saturated fat, refined carbohydrate, low in fiber and high in cholesterol, and a heart healthy diet (HHD) rich in unsaturated fat, unrefined carbohydrate, fruits/vegetables, high in fiber and low in cholesterol, on the composition and function of the gut microbiome. Methods: Thirty-Ossabaw pigs were fed WD or HHD diets with half within each group therapeutically treated with statin (atorvastatin [Lipitor])...
June 2019: Current Developments in Nutrition