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JOURNAL ARTICLE
Jiaxian Zhou, Wenfang Deng, Jiapeng Wu, Hua Xiang, Xiaomei Shen, Jih-Gaw Lin, Yiguo Hong
UNLABELLED: In the nitrogen biogeochemical cycle, the reduction of nitrous oxide (N2 O) to N2 by N2 O reductase, which is encoded by nosZ gene, is the only biological pathway for N2 O consumption. In this study, we successfully isolated a strain of denitrifying Paracoccus denitrificans R-1 from sewage treatment plant sludge. This strain has strong N2 O reduction capability, and the average N2 O reduction rate was 5.10 ± 0.11 × 10-9 µmol·h-1 ·cell-1 under anaerobic condition in a defined medium...
April 22, 2024: Microbiology Spectrum
#22
JOURNAL ARTICLE
P Ježek, A Dlasková, H Engstová, J Špačková, J Tauber, P Průchová, E Kloppel, O Mozheitova, M Jabůrek
Mitochondria (mt) represent the vital hub of the molecular physiology of the cell, being decision-makers in cell life/death and information signaling, including major redox regulations and redox signaling. Now we review recent advances in understanding mitochondrial redox homeostasis, including superoxide sources and H2O2 consumers, i.e., antioxidant mechanisms, as well as exemplar situations of physiological redox signaling, including the intramitochondrial one and mt-to-cytosol redox signals, which may be classified as acute and long-term signals...
April 22, 2024: Physiological Research
#23
JOURNAL ARTICLE
Manimurugan Kanagavel, Rajan Marystella Sparjan Samuvel, Vaikundamoorthy Ramalingam, Sunil Kumar Nechipadappu
This study aimed to repurpose the antifungal drug flucytosine (FCN) for anticancer activity together with cocrystals of nutraceutical coformers sinapic acid (SNP) and syringic acid (SYA). The cocrystal screening experiments with SNP resulted in three cocrystal hydrate forms in which two are polymorphs, namely, FCN-SNP F-I and FCN-SNP F-II, and the third one with different stoichiometry in the asymmetric unit (1:2:1 ratio of FCN:SNP:H2 O, FCN-SNP F-III). Cocrystallization with SYA resulted in two hydrated cocrystal polymorphs, namely, FCN-SYA F-I and FCN-SYA F-II...
April 22, 2024: Molecular Pharmaceutics
#24
JOURNAL ARTICLE
Wei Guo, Nan Wang, Kai-Yue Zhang, Pei-Pei Song, Zhan-Qiang Ma
Metal nanoparticles could be accumulated in soils, which threatens the ecological stability of crops. Investigating the effects of cuprous oxide nanoparticles (Cu2 O-NPs) on photosystem Ⅱ (PSⅡ) of wheat seedling leaves holds considerable importance in comprehending the implications of Cu2 O-NPs on crop photosynthesis. Following the hydroponic method, we investigated the effects of 0, 10, 50, 100, and 200 mg·L-1 Cu2 O-NPs on chlorophyll fluorescence induction kinetics and photosynthetic-related genes in wheat seedlings of "Zhoumai 18"...
March 18, 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
#25
JOURNAL ARTICLE
Yun-Chao Pang, Tian Gao, Xiu-Fen Li, Tong-Bin Zhao, Xing-Chang Wang, Rong-Ping Li, Feng-Yuan Yu, Sheng-Lin Qu, De-Xiong Teng, Jiao-Jun Zhu
The analytical equation based on Monin-Obukhov (M-O) similarity theory ( i.e. , wind profile equation) has been adopted since 1970s for using in the prediction of wind vertical profile over flat terrains, which is mature and accurate. However, its applicability over complex terrains remains unknown. This applicability signifies the accuracy of the estimations of aerodynamic parameters for the boundary layer of non-flat terrain, such as zero-displacement height ( d ) and aerodynamic roughness length ( z0 ), which will determine the accuracy of frequency correction and source area analysis in calculating carbon, water, and trace gas fluxes based on vorticity covariance method...
March 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
#26
JOURNAL ARTICLE
Pablo Lehmann Albornoz, César Sá Bartzen, Luiz R Malabarba
In a recent study based on the generalized mixed Yule coalescent method for delimiting species, a threshold of 2% genetic distance using cytochrome c oxidase subunit I sequences was used to delimit the species of Microglanis. That action resulted in assembling several populations of Microglanis from Atlantic coastal rivers between Rio Grande do Sul and São Paulo states as a single species, Microglanis cottoides, including Microglanis cibelae as a junior synonym. We reexamined these populations and found three species diagnosed by their morphology and that constitute separate mtDNA lineages, including a new species...
April 22, 2024: Journal of Fish Biology
#27
JOURNAL ARTICLE
Meredith O Hope, Ann W Nguyen, Robert Joseph Taylor, Linda Chatters
Spirituality is a significant cultural strength and resource for Black emerging adults. Numerous studies show that increasing numbers of emerging adults tend to identify themselves as being spiritual but not religious. However, no studies to date have identified the demographic correlates of spirituality for Black emerging adults from different ethnic groups (i.e., African American vs. Black Caribbean). Data from the National Survey of American Life was used to identify the demographic correlates of 2 indicators of spirituality (e...
March 2024: Religions
#28
JOURNAL ARTICLE
Anna R Smith, Pi-I D Lin, Sheryl L Rifas-Shiman, Karen M Switkowski, Abby F Fleisch, Robert O Wright, Brent Coull, Emily Oken, Marie-France Hivert, Andres Cardenas
BACKGROUND: Nonessential metals have endocrine disrupting properties, interfere with cellular processes, generate reactive oxygen and deplete antioxidants, while essential metals and vitamins act as antioxidants. The extent to which prenatal metals and vitamins are associated with cord blood hormones involved in maternal and fetal metabolic and growth processes is unknown. METHODS: We measured six nonessential (arsenic, barium, cadmium, cesium, lead, mercury) and four essential (magnesium, manganese, selenium, zinc) metals and trace elements, and two vitamins (B12 and folate) in first trimester blood from participants in the longitudinal pre-birth Project Viva cohort, who were recruited between 1999-2002 in eastern Massachusetts...
December 2023: Global reproductive health
#29
JOURNAL ARTICLE
Rehab Ahmed, Sawsan A Zaitone, Asmaa K K Abdelmaogood, Huda M Atef, Mona F M Soliman, Alaa M Badawy, Howaida S Ali, AbdelNaser Zaid, Hatem I Mokhtar, Lamiaa M Elabbasy, Emad Kandil, Asmaa Mokhtar Yosef, Rama I Mahran
Introduction: Betanin (C₂₄H₂₆N₂O₁₃) is safe to use as food additives approved by the FDA with anti-inflammatory and anticancer effects in many types of cancer cell lines. The current experiment was designed to test the chemotherapeutic effect of the combination of betanin with the standard chemotherapeutic agent, capecitabine, against chemically induced colon cancer in mice. Methods: Bioinformatic approach was designed to get information about the possible mechanisms through which the drugs may control cancer development...
2024: Frontiers in Pharmacology
#30
JOURNAL ARTICLE
Tahreem Arshad, Haji Muhammad Shoaib Khan, Kashif-Ur-Rehman Khan, Abdulaziz S Al-Roujayee, Mohamed Mohany, Maqsood Ahmad, Sana Maryam, Muhammad Bilal Akram, Hasnain Shaukat, Umair Khursheed, Mourad A M Aboul-Soud
The bioactive extracts of traditional medicinal plants are rich in polyphenols and help to rejuvenate skin. The study was designed to assess the skin rejuvenating effects of a stable cream enriched with 4% I. argentea (IaMe) extract. The quantity of polyphenols by spectrophotometric methods was TPC, 101.55 ± 0.03 mg GAE/g and total flavonoid content; 77.14 ± 0.13 mg QE/g, while HPLC-PDA revealed gallic acid; 4.91, chlorogenic acid 48.12, p-coumaric acid 0.43, and rutin 14.23 μg/g...
2024: Frontiers in Pharmacology
#31
JOURNAL ARTICLE
Linh Quang Vo, Anh-Tuan Vu, Thu Dieu Le, Chinh Dang Huynh, Hoang Vinh Tran
A new graphene oxide (GO) nanocomposite that contains chitosan, a biological polymer, combined with a magnetic nanoparticle inorganic material (Fe3 O4 ) was successfully prepared and applied for the adsorption of Pb(II) from aqueous solutions. The structural and morphological properties of the GO/Fe3 O4 /CS (GFC) nanocomposites were characterized by X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. Influent factors for Pb(II) adsorption, including the contacting time, pH of the working medium, working temperature, and adsorbent dosage on the adsorption efficiency, have been optimized...
April 16, 2024: ACS Omega
#32
Karl Marrett, Keivan Moradi, Chris Sin Park, Ming Yan, Chris Choi, Muye Zhu, Masood Akram, Sumit Nanda, Qing Xue, Hyun-Seung Mun, Adriana Gutierez, Mitchell Rudd, Brian Zingg, Gabrielle Magat, Kathleen Wijaya, Hongwei Dong, X William Yang, Jason Cong
Neuronal reconstruction-a process that transforms image volumes into 3D geometries and skeletons of cells- bottlenecks the study of brain function, connectomics and pathology. Unlike artistic domains with similar challenges (e.g., hair modeling), scientists need exact and complete segmentations to study subtle topological differences. Existing methods are diskbound, dense-access, coupled, single-threaded, algorithmically unscalable and require manual cropping of small windows and proofreading of skeletons due to low topological accuracy...
April 9, 2024: bioRxiv
#33
Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V van Dijk, Teresa Guerrero Urbano, Lisa Van den Bosch, Andrew J Hope, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nick West, Max J H Witjes, Alex Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller
PURPOSE: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and at least 16 diagnostic/staging systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely under-diagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ...
April 9, 2024: medRxiv
#34
Chioma M Odo, Luis A Vega, Piyali Mukherjee, Sruti DebRoy, Anthony R Flores, Samuel A Shelburne
The major gram-positive pathogen group A Streptococcus (GAS) is a model organism for studying microbial epidemics as it causes waves of infections. Since 1980, several GAS epidemics have been ascribed to the emergence of clones producing increased amounts of key virulence factors such as streptolysin O (SLO). Herein, we sought to identify mechanisms underlying our recently identified temporal clonal emergence amongst emm4 GAS, given that emergent strains did not produce augmented levels of virulence factors relative to historic isolates...
April 10, 2024: bioRxiv
#35
Dimitrios Pollalis, Constantin Georgescu, Jonathan D Wren, Grigor Tombulyan, Justin M Leung, Pein-An Lo, Clarisa Marie Bloemhof, Ryang Hwa Lee, EunHye Bae, Jeffrey K Bailey, Britney O Pennington, Amir I Khan, Kaitlin R Kelly, Ashley K Yeh, Kartik S Sundaram, Mark Humayun, Stain Louie, Dennis O Clegg, Sun Young Lee
Dysfunction of the retinal pigment epithelium (RPE) is a common shared pathology in major degenerative retinal diseases despite variations in the primary etiologies of each disease. Due to their demanding and indispensable functional roles throughout the lifetime, RPE cells are vulnerable to genetic predisposition, external stress, and aging processes. Building upon recent advancements in stem cell technology for differentiating healthy RPE cells and recognizing the significant roles of small extracellular vesicles (sEV) in cellular paracrine and autocrine actions, we investigated the hypothesis that the RPE-secreted sEV alone can restore essential RPE functions and rescue photoreceptors in RPE dysfunction-driven retinal degeneration...
April 13, 2024: bioRxiv
#36
JOURNAL ARTICLE
Keerati Maneesai, Montree Thongkam, Chaval Sriwong, Chesta Ruttanapun
The Ca12 Al14 O33 ceramic (C12A7) and reduced graphene oxide (rGO) composite which an ultra-high amount (i.e., 40, 50, 60, and 70 wt%) of rGO (ultra-high amount C12A7/rGO composite) were synthesized by a solid-state reaction process. After the hydraulic press, the heat treatment in the temperature range of 773 K under the argon environment had been performed with the composite pellets for 30 min. XRD results of the C12A7 and all the ultra-high amount C12A7/rGO composites indicated a pure phase of C12A7 ceramic...
April 30, 2024: Heliyon
#37
JOURNAL ARTICLE
Qiang Huang, Xin Jin, Lvjia Wu, Jiangdong Li, Qianlu Xing, Xianheng Wang, Changkuo Zhao
A novel method for synthesizing α-aminoalkyl phosphine oxides in aqueous medium, using Ar2 P(O)-H reagents, alcohols and amines, is described. This method: (i) allows for the smooth aminophosphinoylation of alcohols with amines and H-phosphine oxides under mild conditions; (ii) provides an efficient and alternative approach to access various α-aminoalkylphosphine oxides. Although various amines exhibited remarkable versatility and tolerance for functional groups in this reaction, alcohols and H-phosphine oxides demonstrated limited applicability as reactants...
April 22, 2024: Organic & Biomolecular Chemistry
#38
JOURNAL ARTICLE
Zhiming Yang, Lin Peng, Leneng Yang, Mingli Fu, Daiqi Ye, Peirong Chen
Selective catalytic NH3 -to-N2 oxidation (NH3 -SCO) is highly promising for abating NH3 emissions slipped from stationary flue gas after-treatment devices. Its practical application, however, is limited by the non-availability of low-cost catalysts with high activity and N2 selectivity. Here, using defect-rich nitrogen-doped carbon nanotubes (NCNT-AW) as the support, we developed a highly active and durable copper-based NH3 -SCO catalyst with a high abundance of cuprous (Cu+ ) sites. The obtained Cu/NCNT-AW catalyst demonstrated outstanding activity with a T50 (i...
September 2024: Journal of Environmental Sciences (China)
#39
JOURNAL ARTICLE
Haoyu Qiu, Ling Huang, Hanying Wang, Chenzhi Tao, Zhiqiang Ran, Jiahang Xu, Haofeng Sun, Ping Wang
The intensive aquaculture model has resulted in a heightened prevalence of diseases among farmed animals. It is imperative to identify healthy and efficacious alternatives to antibiotics for the sustainable progression of aquaculture. In this investigation, a strain of Lactobacillus acidophilus AC was introduced into the cultural water at varying concentrations (105 CFU/mL, 106 CFU/mL, 107 CFU/mL) to nourish zebrafish (Danio rerio). The findings revealed that L. acidophilus AC effectively increased the growth performance of zebrafish, improved the ion exchange capacity of gills, and enhanced hepatic antioxidant and immune-enzyme activities...
April 19, 2024: Fish & Shellfish Immunology
#40
JOURNAL ARTICLE
Zhi-Chao Li, Min Li, Ling-Xiang Xiao, Xi Zheng, Rong Li, Shi-Jia Dong, Yue Wang, Hong-Yu Wen, Kun-Lin Ruan, Ke-Guang Cheng, Ming Chen, Yan-Hui Tan
One of the effective therapeutic strategies to treat rheumatoid arthritis (RA)-related bone resorption is to target excessive activation of osteoclasts. We discovered that 6-O-angeloylplenolin (6-OAP), a pseudoguaianolide from Euphorbia thymifolia Linn widely used for the treatment of RA in traditional Chinese medicine, could inhibit RANKL-induced osteoclastogenesis and bone resorption in both RAW264.7 cells and BMMs from 1 μM and protect a collagen-induced arthritis (CIA) mouse model from bone destruction in vivo...
April 19, 2024: Biochemical Pharmacology
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