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https://www.readbyqxmd.com/read/29756302/velopharyngeal-dysfunction-from-intranasal-substance-abuse-case-series-and-review-of-literature
#1
Peng You, Linda Chow, Anne Dworschak-Stokan, Murad Husein
OBJECTIVE: Intranasal substance abuse with cocaine or opioids can result in complications involving the midline nasal and oral structures. When the defect involves the velopharyngeal musculature, this leads to velopharyngeal dysfunction (VPD). This article aims to illustrate this clinical entity through a series of four patients and a review of the literature. METHODS: A series of four cases of VPD due to intranasal narcotic use and their management are discussed...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29746919/opioid-medication-use-in-the-surgical-patient-an-assessment-of-prescribing-patterns-and-utilization
#2
Wen Hui Tan, Jennifer Yu, Sara Feaman, Jared M McAllister, Lindsey G Kahan, Mary A Quasebarth, Jeffrey A Blatnik, J Christopher Eagon, Michael M Awad, L Michael Brunt
BACKGROUND: With the epidemic of prescription opioid abuse in the United States, rates of opioid-related unintentional deaths have risen dramatically. However, little data exists comparing postoperative opioid prescriptions with patient use. We sought to better elucidate this relationship in surgical patients. STUDY DESIGN: A prospective cohort study was conducted of narcotic-naïve patients undergoing open and laparoscopic abdominal procedures on a minimally invasive surgery service...
May 7, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29705679/preoperative-smoking-and-narcotic-benzodiazepine-and-tramadol-use-are-risk-factors-for-narcotic-use-after-hip-and-knee-arthroplasty
#3
Kipp A Cryar, Timothy Hereford, Paul K Edwards, Eric Siegel, C Lowry Barnes, Simon C Mears
BACKGROUND: The use of narcotics has been found to be a modifiable risk factor for success of arthroplasty. We sought to determine the risk factors leading to increased narcotic use after total hip arthroplasty and total knee arthroplasty. METHODS: A retrospective chart review was performed on new patients presenting to an orthopedic reconstructive-service clinic. New patients aged 18 years or older with osteoarthritis of the hip or knee who presented over a 1-year period and underwent total knee arthroplasty or total hip arthroplasty were included...
April 9, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29700845/re-racialization-of-addiction-and-the-redistribution-of-blame-in-the-white-opioid-epidemic
#4
Sonia Mendoza, Allyssa Stephanie Rivera, Helena Bjerring Hansen
New York City has the largest number of opioid dependent people of U.S. cities, and within New York, Whites have the highest rate of prescription opioid and heroin overdose deaths. The rise of opioid abuse among Whites has resulted in popular narratives of victimization by prescribers, framing of addiction as a biological disease, and the promise of pharmaceutical treatments that differ from the criminalizing narratives that have historically described urban Latino and black narcotic use. Through an analysis of popular media press and interviews with opioid prescribers and community pharmacists in Staten Island-the epicenter of opioid overdose in New York City and the most suburban and white of its boroughs-we found that narratives of white opioid users disrupted notions of the addict as "other," producing alternative logics of blame that focus on prescribers and the encroachment of dealers from outside of white neighborhoods...
April 27, 2018: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/29681163/patterns-of-narcotic-prescribing-by-orthopedic-surgeons-for-medicare-patients
#5
Matthew R Boylan, Kelly I Suchman, James D Slover, Joseph A Bosco
In recent years, narcotics have been subject to increased regulation and monitoring because of their side effects and potential for misuse. Currently, variation in prescribing patterns of narcotics among orthopedic surgeons is unknown. The Medicare Part D claims database was used to identify orthopedic surgeons who prescribed at least one schedule II or III narcotic during 2014. The median duration of a narcotic prescription was 8.2 days. The median prescription duration was shortest for hand surgeons (5.6 days) and longest for spine surgeons (12...
April 1, 2018: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29657697/characterizing-mortality-from-substance-abuse-in-iran-an-epidemiological-study-during-march-2014-to-february-2015
#6
Fatemeh Shahbazi, Seyed Davood Mirtorabi, Mohammad Reza Ghadirzadeh, Seyed Saeed Hashemi-Nazari, Abdolrazagh Barzegar
Background: Drug abuse is a severe and chronic disorder that leaves morbidity, disability and premature mortality in the society. The study of death due to substance abuse provides useful information for local, national and international administrators. Thus, by identifying the factors that have an impact on overdose-related mortality we can provide suitable intervention for vulnerable groups. The aim of this study was an investigation of mortality rate caused by consumption of narcotic and psychoactive substances in Iran...
July 2017: Addiction & Health
https://www.readbyqxmd.com/read/29599038/neer-award-2018-the-effect-of-preoperative-education-on-opioid-consumption-in-patients-undergoing-arthroscopic-rotator-cuff-repair-a-prospective-randomized-clinical-trial
#7
Usman Ali M Syed, Alexander W Aleem, Charles Wowkanech, Danielle Weekes, Mitchell Freedman, Fotios Tjoumakaris, Joseph A Abboud, Luke S Austin
BACKGROUND: Opioids are commonly administered for the treatment of acute and chronic pain symptoms. The current health care system is struggling to deal with increasing medication abuse and rising mortality rates from overdose. Preoperative patient-targeted education on opioid use is an avenue yet to be explored. The purpose of the study was to determine whether preoperative narcotics education reduces consumption after arthroscopic rotator cuff repair (ARCR). METHODS: Patients undergoing primary ARCR at our institution were randomized to receiving opioid-related preoperative education or not...
March 26, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29582450/tamper-resistant-prescription-forms-for-narcotics-in-france-should-we-generalise-them
#8
Amélie Daveluy, Lucie Sauvaget, Angela Bastien, Maryse Lapeyre-Mestre, Cédric Collin, Nathalie Richard, Françoise Haramburu
In France, prescription of narcotics must be written on a tamper-resistant prescription form with specific technical particularities. Dosage and daily dose of medicines shall be written out entirely in letters. These prescription forms are also mandatory for buprenorphine, clorazepate, clonazepam, tianeptine, buccal midazolam and zolpidem owing to traffic, abuse or diversion. In 2012, to assess the use of standard and tamper-resistant prescription forms and the acceptability of the generalization of the latter to all medicines, a national opinion survey was performed, with a postal questionnaire, within 3 randomized samples of 1,500 prescribers (physicians, dentists and midwives)...
March 27, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29476355/pain-states-the-opioid-epidemic-and-the-role-of-radiologists
#9
REVIEW
Mark R Jones, Alan D Kaye, Laxmaiah Manchikanti, Joshua A Hirsch
PURPOSE OF REVIEW: The prevalence of chronic pain and prescription opioid abuse has resulted in epidemic problems for patients and clinicians. The consequences are taking a heavy toll on patients, physicians, and society. Specific to radiology, a significant need exists for best practice assessment and treatment approaches for pain management, as patients with chronic pain often undergo radiological tests of unclear clinical relevance. RECENT FINDINGS: The USA is amid an opioid-prescribing epidemic and resultant overdose public health emergency...
February 23, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29464692/misconceptions-and-realities-of-the-prescription-opioid-epidemic
#10
Sidney H Schnoll
The abuse of opioids in the US is not a new problem. In 1973 David Musto published his book, The American Disease: Origins of Narcotic Control, which described the problem as dating back to the time of the Civil War. Continued attempts to address it through legislation, law enforcement, prevention, treatment, and the development of less abuseable pain relievers have shown limited success.
February 21, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29397321/using-metabolomics-to-investigate-biomarkers-of-drug-addiction
#11
REVIEW
Reza Ghanbari, Susan Sumner
Drug addiction has been associated with an increased risk for cancer, psychological complications, heart, liver, and lung disease, as well as infection. While genes have been identified that can mark individuals at risk for substance abuse, the initiation step of addiction is attributed to persistent metabolic disruptions occurring following the first instance of narcotic drug use. Advances in analytical technologies can enable the detection of thousands of signals in body fluids and excreta that can be used to define biochemical profiles of addiction...
February 2018: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/29387512/mycobacteremia-from-crushed-hydromorphone-tablet-injection
#12
Joseph M Banno, Katherine Shield, Krunal Patel, Anupam A Sule
Mycobacterium abscessus is a fast growing, non-tubercular mycobacterium (NTM) found in water. NTM bacteremia is usually seen in immunocompromised patients who have intravascular catheters. Mycobacterium abscessus bacteremia is often caused by exposure to contaminated water supply in hemodialysis units. A 28-year-old female with poorly controlled diabetes mellitus, end stage renal disease (on hemodialysis via Ash catheter), and recurrent deep vein thrombosis presented to the hospital with proximal right leg deep vein thrombosis...
November 27, 2017: Curēus
https://www.readbyqxmd.com/read/29370543/driving-under-the-influence-of-alcohol-and-drugs-in-the-eastern-part-of-denmark-in-2015-and-2016-abuse-patterns-and-trends
#13
Kirsten Wiese Simonsen, Kristian Linnet, Brian Schou Rasmussen
OBJECTIVES: The objective of this study was to examine the frequency of psychoactive drugs and alcohol in drivers under suspicion of driving under the influence of drugs and alcohol in 2015 and 2016 in the eastern part of Denmark. The trends in the number of traffic cases sent for drug analysis since 2000 and alcohol analysis since 2011 are also discussed. METHODS: Blood samples from drivers suspected of being under the influence of alcohol and/or medication and/or illicit drugs in 2015 and 2016 were investigated as requested by the police...
January 25, 2018: Traffic Injury Prevention
https://www.readbyqxmd.com/read/29366664/brain-disposition-metabolism-and-behavioral-effects-of-the-synthetic-opioid-ah-7921-in-rats
#14
Jacopo Lucchetti, Claudio M Marzo, Alice Passoni, Federico Moro, Angelo di Clemente, Renzo Bagnati, Luigi Cervo, Marco Gobbi
3,4-Dichloro-N-benzamide (AH-7921) is a cyclohexyl-methylbenzamide derivative with analgesic activity, whose abuse was associated with several fatal intoxications, included in Schedule I of UN Single Convention on Narcotic Drugs. We validated an HPLC-MS/MS method to investigate its brain disposition and metabolism after single and repeated injections; in parallel, we evaluated its central behavioral effects. After an intraperitoneal injection of 10 mg/kg, the analgesic effect appeared after 5 min and persisted up to 4 h; brain absorption was rapid (tmax 30 min) and large (brain-to-plasma ratio 16), with active concentration >700 ng/g...
May 1, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29360020/dentists%C3%A2-prescribing-of-analgesics-for-children-in-british-columbia-canada
#15
Mahyar Etminan, M Reza Nouri, Mohit Sodhi, Bruce C Carleton
OBJECTIVE: Recently, there has been great interest in the use, abuse and over-prescribing of opioid analgesics for children. However, there is a paucity of evidence on patterns of prescribing of both narcotic and non-narcotic analgesics for children by dentists. METHODS: We used a population-wide prescription drug database (PharmaNet) in British Columbia, Canada, to examine prescribing and dispensing of analgesics surrounding dental procedures. We examined all drugs prescribed for children by dentists between 1997 and 2013, as we had access to data on drug doses and days of medication supply...
August 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
https://www.readbyqxmd.com/read/29335074/trends-in-narcotics-and-sedative-use-during-mechanical-ventilation-of-preterm-infants-in-canadian-neonatal-intensive-care-units
#16
(no author information available yet)
OBJECTIVE: Mechanical ventilation (MV) in preterm infants (PTI) causes discomfort. Whether it causes pain is controversial. Meta analysis reviews of published work on PTI during MV have shown no clinically significant impact of opioids on pain scales, and hence not recommended for routine use in neonatal intensive care units (NICUs). Similarly regular use of sedative midazolam is also not recommended. Therefore we hypothesized a downward trend in narcotics and sedatives used in MV of PTI in NICUs...
January 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29279713/tramadol-induced-adrenal-insufficiency-histological-immunohistochemical-ultrastructural-and-biochemical-genetic-experimental-study
#17
Shereen Abdelhakim Abdelaleem, Osama A Hassan, Rasha F Ahmed, Nagwa M Zenhom, Rehab A Rifaai, Nashwa F El-Tahawy
Tramadol is a synthetic, centrally acting analgesic. It is the most consumed narcotic drug that is prescribed in the world. Tramadol abuse has dramatically increased in Egypt. Long term use of tramadol can induce endocrinopathy. So, the aim of this study was to analyze the adrenal insufficiency induced by long term use of tramadol in experimental animals and also to assess its withdrawal effects through histopathological and biochemical genetic study. Forty male albino rats were used in this study. The rats were divided into 4 groups (control group, tramadol-treated group, and withdrawal groups)...
2017: Journal of Toxicology
https://www.readbyqxmd.com/read/29233952/epidemiological-study-of-mortality-rate-from-alcohol-and-illicit-drug-abuse-in-iran
#18
Seyed Mohammad Sadegh Ghoreishi, Fatemeh Shahbazi, Seyed Davood Mirtorabi, Mohammad Reza Ghadirzadeh, Seyed Saeed Hashemi Nazari
BACKGROUND: The estimate of mortality associated with illicit opiate use provides useful information to those directing and monitoring local, national and international policies and programs. This study investigated the epidemiology of mortality due to the illegal consumption of narcotics and psychotropic substances in the Iran to provide evidence-based public health data for useful programs and actions aimed at preventing drug-related mortality. STUDY DESIGN: A cross-sectional study...
October 14, 2017: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/29215840/rethinking-naloxone-overdose-drug-is-only-one-part-of-the-cycle-of-narcotic-abuse
#19
Neal J Richmond
No abstract text is available yet for this article.
February 2017: JEMS: a Journal of Emergency Medical Services
https://www.readbyqxmd.com/read/29179909/surgical-interns-preparedness-for-opioid-prescribing-before-and-after-a-training-intervention
#20
Michael J Nooromid, Neel A Mansukhani, Benjamin W Deschner, Simon Moradian, Nabil Issa, Karen J Ho, Jonah J Stulberg
INTRODUCTION: Exposure to pain management curriculum in medical school is currently variable. This paper reports on formal prescribing education, self-perceived prescribing readiness, and prescribing practices among incoming surgical residents before and after a pain management training session. METHODS: Pre-residency survey of thirty surgical interns at a single urban medical center, followed by a repeat survey after an educational session on prescription writing and opioid abuse...
February 2018: American Journal of Surgery
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