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Oral Microbiology

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https://www.readbyqxmd.com/read/28214914/the-impact-of-bitter-taste-receptor-genetics-on-culturable-bacteria-in-chronic-rhinosinusitis
#1
D I Rom, J M Christensen, R Alvarado, R Sacks, R J Harvey
BACKGROUND: Extra-oral bitter taste receptors have been associated with innate bacterial defence mechanisms. Genetic variation in T2R38 functionality has been shown to be associated with susceptibility to upper respiratory tract infections and chronic rhinosinusitis (CRS). We sought to independently assess the influence of bitter taste receptor genotype on the presence of culturable bacteria in the sinuses. METHODOLOGY: A cross-sectional analysis of patients with CRS undergoing surgery was performed...
February 19, 2017: Rhinology
https://www.readbyqxmd.com/read/28214382/allergic-contact-cheilitis-from-anethole-containing-toothpastes-a-practical-solution
#2
N Horst, J Leysen, T Mellaerts, J Lambert, O Aerts
In patients presenting with therapy-resistant cheilitis, especially when extending to the perioral skin, patch tests should be performed, even in longstanding cases(1-2) . A 55-year-old woman suffered from an oozing cheilitis for three months with erythema, edema and crusting of the lips and perioral skin (Fig. 1). An intra-oral burning sensation, loss of taste and a dry mouth were also present. Microbiological swabs and a blood analysis did not reveal any abnormalities, and the application of topical corticosteroids brought only temporary relief...
February 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28198672/integrated-metagenomic-data-analysis-demonstrates-that-a-loss-of-diversity-in-oral-microbiota-is-associated-with-periodontitis
#3
Dongmei Ai, Ruocheng Huang, Jin Wen, Chao Li, Jiangping Zhu, Li Charlie Xia
BACKGROUND: Periodontitis is an inflammatory disease affecting the tissues supporting teeth (periodontium). Integrative analysis of metagenomic samples from multiple periodontitis studies is a powerful way to examine microbiota diversity and interactions within host oral cavity. METHODS: A total of 43 subjects were recruited to participate in two previous studies profiling the microbial community of human subgingival plaque samples using shotgun metagenomic sequencing...
January 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28185714/choosing-wisely-the-top-5-recommendations-from-the-italian-panel-of-the-national-guidelines-for-the-management-of-acute-pharyngitis-in-children
#4
Elena Chiappini, Barbara Bortone, Giuseppe Di Mauro, Susanna Esposito, Luisa Galli, Massimo Landi, Andrea Novelli, Paola Marchisio, Gian Luigi Marseglia, Nicola Principi, Maurizio de Martino
PURPOSE: With the aim to reduce waste in the health care system and avoid risks associated with unnecessary treatment, the Italian Panel of the National Guidelines for the Management of Acute Pharyngitis in Children joined the Choosing Wisely initiative. METHODS: An ad hoc Choosing Wisely task force was selected to develop a candidate list of items for the top-5 list on pharyngitis medicine. Through a process of literature review and consensus, the final list of 5 items was chosen...
February 6, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28174366/radiofrequency-glow-discharge-as-a-mode-of-disinfection-for-elastomeric-impression-materials
#5
Susan Mathew, Mathew M Alani, K N Velayudhan Nair, Sayij Haridas, P B Reba, Sherin A Thomas
INTRODUCTION: Prosthodontic practice involves procedures in which impressions of the maxillary and mandibular arches are mandatory. Cross infection is one of the major problems that can occur in regular dental practice. Every dentist should take utmost care to prevent cross infection as oral cavity is the source of variety of microorganisms which can often cause diseases that can be fatal. Although precautions, such as wearing of gloves and mask, sterilization of instruments are given importance, the need for disinfection of impressions is often neglected...
February 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28160578/oral-yeast-colonization-throughout-pregnancy
#6
R Rio, L Simões-Silva, S Garro, M-J Silva, Á Azevedo, B Sampaio-Maia
BACKGROUND: Recent studies suggest that placenta may harbour a unique microbiome that may have origin in maternal oral microbiome. Although the major physiological and hormonal adjustments observed in pregnant women lead to biochemical and microbiological modifications of the oral environment, very few studies evaluated the changes suffered by the oral microbiota throughout pregnancy. So, the aim of our study was to evaluate oral yeast colonization throughout pregnancy and to compare it with non-pregnant women...
February 4, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28139481/effect-of-green-tea-mouth-rinse-on-streptococcus-mutans-in-plaque-and-saliva-in-children-an-in-vivo-study
#7
Anil Kumar Goyal, Manohar Bhat, Meenakshi Sharma, Mamta Garg, Abhishek Khairwa, Rakesh Garg
AIMS: This study was conducted to evaluate and compare the antimicrobial efficacy of green tea catechin as a mouth wash on colony count of Streptococcus mutans in children. MATERIALS AND METHODS: A sample size of thirty children was selected out of screened 290 children by simple random sampling between the age group of 7 and 12 years. The study was conducted over a period of 2 weeks. After 24 h of oral prophylaxis, the baseline samples were collected and each group was subjected to mouth rinsing with green tea mouth wash for 2 weeks and further plaque and saliva samples were collected at 1- and 2-week intervals from baseline...
January 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28128084/boils-at-frictional-locations-in-a-patient-with-hidradenitis-suppurativa
#8
Jurr Boer, Dalibor Mihajlovic
Dear Editor, Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease. The primary clinical presentation are painful inflamed nodules or boils of inverse areas, i.e. the axillary and anogenito-crural regions, but it can also involve the infra- and inter-mammary regions (1,2). The etiology of HS is not clearly defined. Obesity, smoking, and genetic factors are considered important risk factors. In addition, it has also been suggested that friction may contribute to the development of HS, especially in the obese, but this is based on highly anecdotal reports (3-5)...
December 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28126558/formulating-a-poorly-water-soluble-drug-into-an-oral-solution-suitable-for-paediatric-patients-lorazepam-as-a-model-drug
#9
A C van der Vossen, I van der Velde, O S N M Smeets, D J Postma, M Eckhardt, A Vermes, B C P Koch, A G Vulto, L M Hanff
INTRODUCTION: Many drugs are unavailable in suitable oral paediatric dosage forms, and pharmacists often have to compound drugs to provide paediatric patients with an acceptable formulation in the right dose. Liquid formulations offer the advantage of dosing flexibility and ease of administration to young patients, but drug substances often show poor aqueous solubility. The objective of this work was to study different solvents and matrices to design a liquid formulation for poorly water soluble drugs, using lorazepam as model drug...
January 23, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28125168/prednisone-treatment-in-infertile-patients-with-oligozoospermia-and-accessory-gland-inflammatory-alterations
#10
D Milardi, G Luca, G Grande, M Ghezzi, N Caretta, G Brusco, G De Filpo, R Marana, A Pontecorvi, R Calafiore, C Foresta, A Garolla
The association between inflammation of the male reproductive system and oligozoospermia has been frequently reported in the clinical work-up of male infertility. To improve sperm parameters in infertile patients with genital inflammation, many phytochemical and nutraceutical drugs are currently being used. However, their use is still empirical and no conclusive data have been provided about their efficacy. The treatment with steroid anti-inflammatory drugs might be useful in reducing inflammation and improving sperm parameters, thus increasing the fertility outcome...
January 26, 2017: Andrology
https://www.readbyqxmd.com/read/28120698/short-course-daptomycin-lock-and-systemic-therapy-for-catheter-related-bloodstream-infections-a-retrospective-cohort-study-in-cancer-patients-with-surgically-implanted-devices
#11
Matteo Vassallo, Pierre-Luc Genillier, Brigitte Dunais, Regis Kaphan, Laurence Saudes, Yannick Duval, Fabien Rolland, Valerie Jullien, Nicolas Weiss, Elea Blanchouin, Annick Boscagli, Christophe Perrin, Nathalie Montagne
PURPOSE: Few in vivo studies have been reported describing efficacy and duration of antibiotic lock therapy (ALT) with daptomycin (DPT) for long-term catheter-related bloodstream infections (CRBSI) due to coagulase-negative staphylococci (CoNS). We retrospectively analysed the efficacy of short-course ALT with DPT in combination with systemic treatment (ST) for CoNS-associated CRBSI in our hospital. METHODS: Patients admitted for CoNS-associated CRBSI and treated with DPT as ALT and ST were retrospectively analysed...
January 25, 2017: Journal of Chemotherapy
https://www.readbyqxmd.com/read/28108978/treatment-of-complicated-urinary-tract-infection-and-acute-pyelonephritis-by-short-course-intravenous-levofloxacin-750%C3%A2-mg-day-or-conventional-intravenous-oral-levofloxacin-500%C3%A2-mg-day-prospective-open-label-randomized-controlled-multicenter-non-inferiority
#12
Hong Ren, Xiao Li, Zhao-Hui Ni, Jian-Ying Niu, Bin Cao, Jie Xu, Hong Cheng, Xiao-Wen Tu, Ai-Min Ren, Ying Hu, Chang-Ying Xing, Ying-Hong Liu, Yan-Feng Li, Jun Cen, Rong Zhou, Xu-Dong Xu, Xiao-Hui Qiu, Nan Chen
OBJECTIVE: To compare the efficacy and safety of short-course intravenous levofloxacin (LVFX) 750 mg with a conventional intravenous/oral regimen of LVFX 500 mg in patients from China with complicated urinary tract infections (cUTIs) and acute pyelonephritis (APN). METHODS: This was a prospective, open-label, randomized, controlled, multicenter, non-inferiority clinical trial. Patients with cUTI and APN were randomly assigned to a short-course therapy group (intravenous LVFX at750 mg/day for 5 days) or a conventional therapy group (intravenous/oral regimen of LVFX at 500 mg/day for 7-14 days)...
January 20, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28101333/behaviour-change-interventions-to-influence-antimicrobial-prescribing-a-cross-sectional-analysis-of-reports-from-uk-state-of-the-art-scientific-conferences
#13
T M Rawson, L S P Moore, A M Tivey, A Tsao, M Gilchrist, E Charani, A H Holmes
BACKGROUND: To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration has been recommended. We analysed major UK scientific research conferences to investigate AMS behaviour change intervention reporting. METHODS: Leading UK 2015 scientific conference abstracts for 30 clinical specialties were identified and interrogated. All AMS and/or antimicrobial resistance(AMR) abstracts were identified using validated search criteria...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28100279/severe-community-acquired-adenovirus-pneumonia-treated-with-oral-ribavirin-a-case-report
#14
Byung Woo Yoon, Yong Geon Song, Seung Hyeun Lee
BACKGROUND: Adenovirus is a common pathogen of acute upper respiratory infection in children and is generally self-limiting. Severe adenovirus infections have been reported in immunocompromised hosts especially bone marrow transplantation recipients due to hematologic malignancy. Severe adenovirus pneumonia in immunocompetent hosts has rarely been reported and optimal treatment has not been established. We report a case of community-acquired severe adenovirus pneumonia which was successfully treated with early administration of oral ribavirin...
January 18, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28093536/noma-overview-of-a-neglected-disease-and-human-rights-violation
#15
M Leila Srour, Klaas Marck, Denise Baratti-Mayer
Noma is an orofacial gangrene affecting malnourished children and mainly observed in tropical countries, particularly sub-Saharan Africa. Epidemiological data on noma are scarce, but a current estimate of the global incidence is 30,000-40,000 cases per year, with a mortality rate of approximately 85% and a burden of disease calculated to be a loss of 1-10 million disability-adjusted life years. The etiology of noma is multifactorial with malnutrition as an ever present factor, often in combination with concomitant diseases, such as measles, malaria, and human immunodeficiency virus (HIV), and poor oral hygiene...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28066103/efficacy-and-tolerability-of-topical-sertaconazole-versus-topical-terbinafine-in-localized-dermatophytosis-a-randomized-observer-blind-parallel-group-study
#16
Dattatreyo Chatterjee, Sudip Kumar Ghosh, Sukanta Sen, Saswati Sarkar, Avijit Hazra, Radharaman De
OBJECTIVE: Epidermal dermatophyte infections most commonly manifest as tinea corporis or tinea cruris. Topical azole antifungals are commonly used in their treatment but literature suggests that most require twice-daily application and provide lower cure rates than the allylamine antifungal terbinafine. We conducted a head-to-head comparison of the effectiveness of the once-daily topical azole, sertaconazole, with terbinafine in these infections. MATERIALS AND METHODS: We conducted a randomized, observer-blind, parallel group study (Clinical Trial Registry India [CTRI]/2014/09/005029) with adult patients of either sex presenting with localized lesions...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28045312/black-stains-a-microbiological-analysis-and-a-view-on-familiarity-and-susceptibility-to-tooth-decay-of-patients-in-childhood
#17
D Tripodi, D Martinelli, M Pasini, M R Giuca, S D'Ercole
AIM: Assess prevalence, familial predisposition and susceptibility to caries of Black Stains (BS). Evaluate the microbiological composition of BS, saliva and subgingival plaque. MATERIALS AND METHODS: Sixty nine subjects with BS (test group) and 120 subjects without BS (control group) were analysed for oral status. For each BS-patient, a BS-deposit, 1 ml of saliva and subgingival plaque were collected and microbiologically analysed. Five deciduous teeth with BS were observed under SEM...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28042438/the-treatment-of-peri-implant-diseases-a-new-approach-using-hybenx-%C3%A2-as-a-decontaminant-for-implant-surface-and-oral-tissues
#18
M A Lopez, M Andreasi Bassi, L Confalone, F Silvestre, C Arcuri
PURPOSE: The aim of the present study is to demonstrate the efficacy of HyBeNX® to decontaminate the implant surface, both in the case mucositis and severe peri-implantitis and to allow future bone regeneration. MATERIALS AND METHODS: We describe three case reports of peri-implantitis successfully treated with HyBeNX®. In our study, we have used microbiological tests to demonstrate the efficacy of HyBeNX® in decreasing bacterial load. RESULTS: The microbiological results of the clinical cases described show that there was a reduction in the total bacterial count after treatment...
July 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28028395/microbiological-assessment-of-moringa-oleifera-extracts-and-its-incorporation-in-novel-dental-remedies-against-some-oral-pathogens
#19
Hanaa Elgamily, Amani Moussa, Asmaa Elboraey, Hoda El-Sayed, Marwa Al-Moghazy, Aboelfetoh Abdalla
AIM: To assess the antibacterial and antifungal potentials of different parts of Moringa oleifera plant using different extraction methods in attempts to formulate natural dental remedies from this plant. MATERIAL AND METHODS: Three solvents extracts (Ethanol, acetone, and ethyl acetate) of different parts of Egyptian Moringa tree were prepared and tested against oral pathogens: Staphylococcus aureus, Streptococcus mutans, and Candida albicans using disc diffusion method; As well as to incorporate the plant extract to formulate experimental toothpaste and mouthwash...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28017477/executive-summary-of-the-diagnosis-and-treatment-of-urinary-tract-infection-guidelines-of-the-spanish-society-of-clinical-microbiology-and-infectious-diseases-seimc
#20
Marina de Cueto, Luis Aliaga, Juan-Ignacio Alós, Andres Canut, Ibai Los-Arcos, Jose Antonio Martínez, Jose Mensa, Vicente Pintado, Dolors Rodriguez-Pardo, Jose Ramon Yuste, Carles Pigrau
Most urinary tract infections (UTI) are uncomplicated infections occurring in young women. An extensive evaluation is not required in the majority of cases, and they can be safely managed as outpatients with oral antibiotics. Escherichia coli is by far the most common uropathogen, accounting for >80% of all cases. Other major clinical problems associated with UTI include asymptomatic bacteriuria, and patients with complicated UTI. Complicated UTIs are a heterogeneous group associated with conditions that increase the risk of acquiring infection or treatment failure...
December 22, 2016: Enfermedades Infecciosas y Microbiología Clínica
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