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Ricardo Noguera Louzada, Daniela Ferrara, Eduardo Amorim Novais, Eric Moult, Emily Cole, Mark Lane, James Fujimoto, Jay S Duker, Caroline R Baumal
To describe the appearance of a scleral-derived feeder vessel in a highly myopic eye with secondary choroidal neovascularization (CNV) as visualized on both en face high-speed swept-source (SS) optical coherence tomography angiography (OCTA) prototype, and a commercially available spectral-domain (SD) OCTA, with the corresponding en face and cross-sectional structural OCT images. In this case report, a 60-year-old white male presented with high myopia and secondary CNV in the right eye, previously treated with anti-vascular endothelial growth factor, and was imaged on both SD-OCT and SS-OCT...
October 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
K M Ratheesh, L K Seah, V M Murukeshan
The automatic calibration in Fourier-domain optical coherence tomography (FD-OCT) systems allows for high resolution imaging with precise depth ranging functionality in many complex imaging scenarios, such as microsurgery. However, the accuracy and speed of the existing automatic schemes are limited due to the functional approximations and iterative operations used in their procedures. In this paper, we present a new real-time automatic calibration scheme for swept source-based optical coherence tomography (SS-OCT) systems...
October 14, 2016: Physics in Medicine and Biology
Yu Ichioka, Akihito Uji, Nagahisa Yoshimura
BACKGROUND: To present an intraoperative acute Descemet's fold formation using swept-source optical coherence tomography (SS-OCT) imaging. CASE REPORT: A 67-year-old man complaining of reduced visual acuity in the left eye. A 25-gauge pars plana vitrectomy combined with phacoemulsification cataract surgery was performed to remove the vitreomacular traction. When hydro-sealing was performed, striae rapidly spread in the cornea. SS-OCT B-scan images performed on postoperative day 1 revealed a wavy Descemet's membrane that might correspond to Descemet's folds...
May 2016: Case Reports in Ophthalmology
Tomoka Ueno, Yasushi Shimada, Khairul Matin, Yuan Zhou, Ikumi Wada, Alireza Sadr, Yasunori Sumi, Junji Tagami
The aim of this study was to evaluate the signal intensity and signal attenuation of swept source optical coherence tomography (SS-OCT) for dental caries in relation to the variation of mineral density. SS-OCT observation was performed on the enamel and dentin artificial demineralization and on natural caries. The artificial caries model on enamel and dentin surfaces was created using Streptococcus mutans biofilms incubated in an oral biofilm reactor. The lesions were centrally cross sectioned and SS-OCT scans were obtained in two directions to construct a three-dimensional data set, from the lesion surface (sagittal scan) and parallel to the lesion surface (horizontal scan)...
July 2016: Journal of Medical Imaging
Sarah Cheng, Theodore Leng
BACKGROUND AND OBJECTIVES: A method of identifying retinal vascular microaneurysms (MAs) in nonproliferative diabetic retinopathy (NPDR) using swept-source optical coherence tomography (SS-OCT). PATIENTS AND METHODS: SS-OCT images were acquired in 17 eyes with NPDR using prototype SS-OCT device and fluorescein angiography (FA) images were obtained simultaneously. MAs identified on SS-OCT slabs were correlated to MAs identified on FA. RESULTS: MAs were identified in SS-OCT slabs in 15/17 eyes, resulting in NPDR diagnosis rate of 88%...
2016: Clinical Ophthalmology
Wenwen He, Xiangjia Zhu, Don Wolff, Zhennan Zhao, Xinghuai Sun, Yi Lu
Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression were used to investigate gender, age, operated eye, posterior vitreous detachment, lens opacity grading, and axial length (AXL) related variables capable of influencing the ACV. Results. The average ACV was 139...
2016: Journal of Ophthalmology
Colm McAlinden, Qinmei Wang, Rongrong Gao, Weiqi Zhao, Ayong Yu, Yu Li, Yan Guo, Jinhai Huang
PURPOSE: To compare a new swept source optical coherence tomography (SS-OCT) based biometer (OA-2000) with the IOLMaster v5.4 (partial coherence interferometry) and Aladdin (optical low-coherence interferometry) biometers in terms of axial length measurement and failure rate in eyes with cataract. DESIGN: Reliability study METHODS: A total of 377 eyes of 210 patients were scanned with the three biometers in a random order. For each biometer, the number of unobtainable axial length measurements was recorded and grouped as per the type and severity of cataract based on the Lens Opacities Classification System III by the same experienced ophthalmologist...
September 21, 2016: American Journal of Ophthalmology
Kumar Sambhav, Sandeep Grover, K V Chalam
PURPOSE: Swept Source Optical Coherence Tomography validates lamina cribrosa anomaly in optic disk pit. METHOD: Observational case report. RESULTS: A 25-year-old African American male presented with decreased vision in right eye of 4 days duration. Best corrected visual acuity (BCVA) for distance in right eye was 20/200 and in left eye was 20/20. Dilated fundus examination of right eye showed serous macular detachment of entire posterior pole along with an optic pit on temporal margin of optic disk...
September 22, 2016: Retinal Cases & Brief Reports
Yuya Takubo, Takuma Shirahata, Shinji Yamashita
We optimized parameters of a dispersion-tuned wavelength-swept fiber laser by numerically analyzing dynamic characteristics. The optimized laser is experimentally demonstrated and applied to the swept-source optical coherence tomography (SS-OCT) system. The dispersion-tuned wavelength-swept laser (DT-WSL) is a unique tunable fiber laser, whose lasing wavelength can be tuned rapidly without any mechanical tunable filters. Although the wavelength of a DT-WSL can be swept rapidly and widely, the broadening of the instantaneous spectral width at a high sweep rate has been a critical drawback for SS-OCT applications...
September 20, 2016: Applied Optics
Yong Woo Kim, Jin Wook Jeoung, Michael J A Girard, Jean Martial Mari, Ki Ho Park
PURPOSE: To investigate the variation of lamina cribrosa (LC) structure based on the baseline intraocular pressure (IOP) in eyes with primary open-angle glaucoma (POAG) and healthy individuals using swept-source optical coherence tomography. METHODS: A total of 108 eyes with POAG and 61 healthy eyes were recruited. Based on the baseline IOP, the POAG eyes were divided into higher-baseline IOP (HTG; baseline IOP > 21 mmHg, n = 38 eyes) and lower-baseline IOP (NTG; baseline IOP ≤ 21 mmHg, n = 70 eyes)...
2016: PloS One
Sang Yeop Lee, Hyoung Won Bae, Hee Jung Kwon, Gong Je Seong, Chan Yun Kim
PURPOSE OF THE STUDY: The purpose of the study was to evaluate the clinical efficacy of swept-source optical coherence tomography (SS-OCT), we compared the intradevice repeatability of thickness measurements obtained using SS-OCT to that of measurements obtained using spectral domain OCT (SD-OCT), and assessed the interdevice agreement of thickness measurements. MATERIALS AND METHODS: This cross-sectional prospective study involved 3 consecutive measurements of peripapillary retinal nerve fiber layer (PP-RNFL) and ganglion cell-inner plexiform layer thickness in healthy subjects, using 2 different OCT systems...
September 2, 2016: Journal of Glaucoma
Naoko Takada, Kazuko Omodaka, Tsutomu Kikawa, Airi Takagi, Akiko Matsumoto, Yu Yokoyama, Yukihiro Shiga, Kazuichi Maruyama, Hidetoshi Takahashi, Masahiro Akiba, Toru Nakazawa
PURPOSE: To objectively classify the optic discs of open-angle glaucoma (OAG) patients into Nicolela's four disc types, i.e., focal ischemic (FI), myopic (MY), senile sclerotic (SS), and generalized enlargement (GE), with swept-source optical coherence tomography (SS-OCT). METHODS: This study enrolled 113 eyes of 113 OAG patients (mean age: 62.5 ± 12.6; Humphrey field analyzer-measured mean deviation: -9.4 ± 7.3 dB). Newly developed software was used to quantify a total of 20 optic disc parameters in SS-OCT (DRI OCT-1, TOPCON) images of the optic disc...
2016: PloS One
Margaret A Greven, Zachary Elkin, Ryan W Nelson, Theodore Leng
BACKGROUND AND OBJECTIVE: To describe en face swept-source optical coherence tomography (SS-OCT) imaging of epiretinal membranes (ERMs) and the underlying retinal nerve fiber layer (RNFL). PATIENTS AND METHODS: SS-OCT images were captured in nine eyes with ERMs. These SS-OCT en face images were qualitatively compared to spectral-domain OCT (SD-OCT) en face images. Using SS-OCT, en face images of the RNFL were obtained, if possible. RESULTS: En face SS-OCT images of ERMs were obtained in all nine eyes of eight individuals with clinically diagnosed ERMs that were superior to SD-OCT images...
August 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Mark Lane, Eric M Moult, Eduardo A Novais, Ricardo N Louzada, Emily D Cole, ByungKun Lee, Lennart Husvogt, Pearse A Keane, Alastair K Denniston, André J Witkin, Caroline R Baumal, James G Fujimoto, Jay S Duker, Nadia K Waheed
PURPOSE: To investigate the appearance of choriocapillaris (CC) flow under drusen by comparing long-wavelength (1050 nm) swept-source optical coherence tomography (SS-OCT) angiography with shorter-wavelength (840 nm) spectral-domain (SD) OCT angiography. METHODS: Patients with drusen imaged on both devices on the same day were selected and graded. Ambiguous OCT angiography (OCTA) signal loss was defined as low OCTA signal on the en face OCTA CC image that also had low OCT signal in the corresponding area on the en face OCT CC image and OCT B-scans...
July 1, 2016: Investigative Ophthalmology & Visual Science
Akihito Uji, Yuki Muraoka, Nagahisa Yoshimura
PURPOSE: The purpose of this study was to investigate a novel imaging technique to identify the continuous posttrabecular aqueous outflow pathway from a single B-scan, using swept-source optical coherence tomography (SS-OCT). METHODS: Three-dimensional volume scans of the temporal or nasal side of the anterior segment area at the limbus were acquired from 11 eyes of 11 healthy subjects, using SS-OCT. The aqueous outflow pathway was identified using an en face OCT image and reconstructed images of the vasculature (vasculature map)...
August 1, 2016: Investigative Ophthalmology & Visual Science
Kenneth J Hoffer, Peter C Hoffmann, Giacomo Savini
PURPOSE: To investigate agreement between the IOLMaster 700 based on swept-source optical coherence tomography (SS-OCT) and the Lenstar LS 900 based on optical low-coherence reflectometry (OLCR). SETTING: Private practice, Castrop-Rouxelle, Germany. DESIGN: Prospective evaluation of diagnostic test. METHODS: Axial length (AL), keratometry (K), anterior chamber depth (corneal epithelium to lens) (ACD), lens thickness, and central corneal thickness (CCT) were measured in 183 eyes of 183 patients...
August 2016: Journal of Cataract and Refractive Surgery
Ruchire Eranga Wijesinghe, Seung-Yeol Lee, Pilun Kim, Hee-Young Jung, Mansik Jeon, Jeehyun Kim
The feasibility of using the bio-photonic imaging technique to assess symptoms of circular leaf spot (CLS) disease in Diospyros kaki (persimmon) leaf samples was investigated. Leaf samples were selected from persimmon plantations and were categorized into three groups: healthy leaf samples, infected leaf samples, and healthy-looking leaf samples from infected trees. Visually non-identifiable reduction of the palisade parenchyma cell layer thickness is the main initial symptom, which occurs at the initial stage of the disease...
2016: Sensors
Zofia Michalewska, Janusz Michalewski, Jerzy Nawrocki
OBJECTIVE: The aim of this article is to report on retinal and choroidal morphology in choroidal nevi documented with Swept Source optical coherence tomography (SS-OCT). DESIGN: This is a retrospective, observational study. PARTICIPANTS: We included 27 consecutive patients with choroidal nevi. Mean age was 66.3 years (21-95 years). METHODS: The SS-OCT scanning protocol consisted of a single line scan through the centre of the nevi with a resolution of 3 µm, built from 1024 A-scans, with a length of 12 mm...
August 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Jacqueline Chua, Sri Gowtham Thakku, Tin A Tun, Monisha E Nongpiur, Marcus Chiang Lee Tan, Michael J A Girard, Tien Yin Wong, Joanne Hui Min Quah, Tin Aung, Ching-Yu Cheng
PURPOSE: To determine the association of iris surface features with iris volume change after physiologic pupil dilation in adults. DESIGN: Cross-sectional observational study. PARTICIPANTS: Chinese adults aged ≥ 50 years without ocular diseases. METHODS: Digital iris photographs were taken from eyes of each participant and graded for crypts (by number and size) and furrows (by number and circumferential extent) following a standardized grading scheme...
October 2016: Ophthalmology
N Murata, T Togano, D Miyamoto, S Ochiai, T Fukuchi
PurposeTo investigate the prevalence of microcystic macular edema (MME) in patients with glaucoma and the relationship between glaucomatous visual field defects and MME.Patients and methodsWe analyzed 636 eyes of 341 glaucoma patients who underwent spectral domain optical coherence tomography (SD-OCT). MME was defined as vacuoles observed in the inner nuclear layer (INL) on SD-OCT. Quantitative assessment of MME area was performed using en-face imaging obtained swept-source OCT (SS-OCT) and Adobe Photoshop CS6 Extended software...
August 12, 2016: Eye
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