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Zeeshan Akhtar, Pukhraj Rishi, Ramasubramanian Srikanth, Ekta Rishi, Muna Bhende, Rajiv Raman
AIM: To determine choroidal thickness in healthy Indian subjects using Swept source optical coherence tomography (SS-OCT). METHODS: In this prospective, observational, cross-sectional study; healthy Indian subjects (n = 230) with no history of ocular and/or systemic disorders were enrolled in the study. Choroidal thickness was measured for 230 eyes using SS-OCT. Subjects were divided into six age groups. Main outcome measures were subfoveal choroidal thickness (SFCT) and macular choroidal thickness (MCT) up to 3 mm at 500-micron interval from the fovea was measured in eight different quadrants...
2018: PloS One
Kosei Shinohara, Noriko Tanaka, Jost B Jonas, Noriaki Shimada, Muka Moriyama, Takeshi Yoshida, Kyoko Ohno-Matsui
PURPOSE: To investigate the relationships between myopic macular retinoschisis (MRS) and posterior staphylomas and to reveal the characteristics of other retinal lesions associated with MRS. DESIGN: Retrospective, observational case series. PARTICIPANTS: Seven hundred twenty-nine eyes of 420 patients with high myopia, which was defined as myopic refractive error of more than -8.0 diopters or an axial length longer than 26.5 mm. METHODS: Highly myopic eyes were examined by ultrawide-field (UWF) swept-source (SS) OCT with scan width of up to 23 mm and scan depth of 5 mm...
April 28, 2018: Ophthalmology
Matthias Salas, Marco Augustin, Franz Felberer, Andreas Wartak, Marie Laslandes, Laurin Ginner, Michael Niederleithner, Jason Ensher, Michael P Minneman, Rainer A Leitgeb, Wolfgang Drexler, Xavier Levecq, Ursula Schmidt-Erfurth, Michael Pircher
Imaging of the human retina with high resolution is an essential step towards improved diagnosis and treatment control. In this paper, we introduce a compact, clinically user-friendly instrument based on swept source optical coherence tomography (SS-OCT). A key feature of the system is the realization of two different operation modes. The first operation mode is similar to conventional OCT imaging and provides large field of view (FoV) images (up to 45° × 30°) of the human retina and choroid with standard resolution...
April 1, 2018: Biomedical Optics Express
Chihiro Matsuura, Yasushi Shimada, Alireza Sadr, Yasunori Sumi, Junji Tagami
The aims of this study were to assess the diagnostic accuracy of swept-source optical coherence tomography (SS-OCT) for detection of caries beneath composite restorations and to compare the results with those obtained by radiography. Flat dentin surfaces with and without natural caries were bonded with 1- or 2-mm thick composite restorations. SS-OCT scanning was performed over the composite restorations to construct three-dimensional (3D) images of the resin-dentin interface. Images were chosen from the 3D constructions to detect caries beneath the restorations...
April 17, 2018: Dental Materials Journal
Imène Zhioua Braham, Imen Ammous, Rim Maalej, Majdi Boukari, Ilhem Mili Boussen, Khalil Errais, Raja Zhioua
BACKGROUND: To report the results of multimodal imaging of a biochemically confirmed case of a family with gyrate atrophy (GA) associated with foveoschisis and macular pseudohole. CASE PRESENTATION: Two sisters presented to us with progressive bilateral decreased vision. The 26-year old sister had a best corrected visual acuity (BCVA) of 20/32 in the right eye (RE) and 20/100 in the left eye (LE). Dilated fundus examination revealed multiple bilateral chorioretinal atrophy areas in the midperipheral and peripheral retina...
April 12, 2018: BMC Ophthalmology
Kai Gao, Fei Li, Yingqi Li, Xingyi Li, Wenbin Huang, Shida Chen, Yaoming Liu, Tin Aung, Xiulan Zhang
Purpose: To compare the anterior and posterior choroid thickness (ACT and PCT, respectively) in primary open-angle glaucoma (POAG), primary angle-closure disease (PACD), and healthy control subjects. Methods: A total of 29 POAG patients (56 eyes), 37 PACD patients (64 eyes), and 34 healthy volunteers (68 eyes) were enrolled in this study; 50 POAG eyes were divided into 25 early/moderate-stage and 25 advanced-stage eyes by visual field loss, while 64 PACD eyes were classified as primary angle-closure suspect (PACS), 8 eyes; primary angle closure (PAC), 18 eyes; and primary angle-closure glaucoma (PACG), 38 eyes...
March 1, 2018: Investigative Ophthalmology & Visual Science
Eun Hee Hong, Yong Un Shin, Min Ho Kang, Heeyoon Cho, Mincheol Seong
PURPOSE: To determine glaucoma-discriminating abilities of macular and circumpapillary retinal nerve fiber layer (cpRNFL) thickness measurements of wide scan (12X9mm) using swept-source optical coherence tomography (SS-OCT) compared to measurements of standard macula and disc scans (6 X 6 mm). METHODS: This retrospective chart review study included 60 glaucomatous and 62 healthy eyes of total 122 subjects who visited a glaucoma clinic and were examined with wide, standard macula, and standard disc scans of SS-OCT (DRI-OCT-1 Atlantis; Topcon Inc...
2018: PloS One
Cindy Ung, Inês Laíns, Rebecca F Silverman, Russell Woods, Anne Marie Lane, Thanos D Papakostas, Deeba Husain, Joan W Miller, Evangelos S Gragoudas, Ivana K Kim, John B Miller
AIMS: The aim of our study was to image choroidal lesions with swept-source optical coherence tomography (SS-OCT) and to identify the morphological characteristics associated with optimal visualisation. METHODS: This was a prospective, cross-sectional study. Patients with choroidal melanocytic lesions <3 mm in thickness on B-scan ultrasonography were recruited. All participants underwent SS-OCT. On SS-OCT we evaluated qualitative (eg, lesion outline, detection of scleral-choroidal interface and quality of the image) and quantitative (measurement of maximum lesion thickness and the largest basal diameter) parameters...
March 31, 2018: British Journal of Ophthalmology
Siddharth Narendran, George Manayath, Narendran Venkatapathy
BACKGROUND/AIMS: Choroidal thickness measurements are reported to differ between spectral-domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT). The aim of this study was to assess the comparability of choroidal thickness measurements using SS-OCT and SD-OCT devices among normal participants. MATERIALS AND METHODS: This was a prospective study of 31 (62 eyes) normal participants. Choroidal imaging was performed sequentially with the Spectralis OCT (SD-OCT) and the deep range imaging OCT (DRI OCT-1) (SS-OCT) using standardized imaging protocols...
January 2018: Oman Journal of Ophthalmology
Jung Yeob Han, Dong Cheol Lee, Se Youp Lee
PURPOSE: To evaluate the efficacy of anterior segment swept-source optical coherence tomography (SS-OCT) for examining horizontal extraocular muscle thickness, distance from the corneal limbus to the insertion of the horizontal extraocular muscle (limbus to insertion distance), and scleral thickness in Korean pediatric strabismus patients. METHODS: This study included pediatric strabismus patients between 5 and 10 years of age. Children with any ocular disease other than strabismus or a history of ocular surgery were excluded...
April 2018: Korean Journal of Ophthalmology: KJO
Hellen Cs Römkens, Henny Jm Beckers, Jan Sag Schouten, Tos Tjm Berendschot, Carroll Ab Webers
Purpose: The aim of this study is to generate reference values for anterior chamber morphometrics to facilitate the interpretation of anterior chamber images acquired with swept-source optical coherence tomography (SS-OCT) in a Caucasian population. Materials and methods: Non-glaucomatous Caucasian subjects, who were newly referred to the outpatient department of the University Eye Clinic Maastricht UMC+, were asked to undergo anterior segment assessment with SS-OCT imaging prior to routine eye examination (including visual acuity and refractive error measurements, Goldmann applanation tonometry, slit lamp examination and funduscopy)...
2018: Clinical Ophthalmology
Yana Fu, Wuying Zhou, Wei Li, Xiaolei Lin, Qi Dai
RATIONALE: The incidence of cornea disorders after laser peripheral iridotomy (LPI) is extremely low. However, cornea Descemet membrane detachment (DMD) combined with corneal decompensation after LPI could still occur. PATIENT CONCERNS: A 69-year-old Chinese woman presented with persistent widespread corneal edema and inferior bullous lesions in her right eye for half a year. She had undergone LPI in both eyes 10 years ago for a prophylactic treatment. The patient received a detailed examination of vivo corneal confocal microscopy and sept-source optical coherence tomography (SS-OCT)...
March 2018: Medicine (Baltimore)
Jorge Espigares, Juri Hayashi, Yasushi Shimada, Junji Tagami, Alireza Sadr
This study evaluated low-viscosity resin potential as enamel marginal gap sealant for existing composite restoration. Standard restorations with marginal gaps were created in bovine teeth; gaps were resealed using G-Bond Plus (GB, GC, Tokyo, Japan) or Icon (ICN, DMG, Hamburg, Germany) with or without HCl pretreatment (n=8). Swept-source optical coherence tomography (SS-OCT) images were taken before and after resealing of the margin and thermal cycling to calculate enamel marginal gap extent. Cross-sectional microscopy was performed to confirm SS-OCT findings...
March 30, 2018: Dental Materials Journal
Satoshi Katagiri, Shin Tanaka, Tadashi Yokoi, Takaaki Hayashi, Emiko Matsuzaka, Kazuko Ueda, Tomoyo Yoshida-Uemura, Akira Arakawa, Sachiko Nishina, Kazuaki Kadonosono, Noriyuki Azuma
Purpose: To report the clinical and genetic findings of a male toddler who presented bilateral bullous retinoschisis with a novel RS1 mutation. Observations: This is an observational case report of a patient referred to our hospital with esotropia. A comprehensive ophthalmic examination was performed with the boy (age, 1 year 4 months) under general anesthesia that included fundus examinations, fluorescein angiography (FA), swept-source optical coherence tomography (SS-OCT), and full-field electroretinography (FF-ERG)...
April 2017: American Journal of Ophthalmology Case Reports
Nino Hirnschall, Ralph Varsits, Birgit Doeller, Oliver Findl
INTRODUCTION: The aim of this study was to find cases in which the axial eye length could not be measured with partial coherence interferometry (PCI) technology and to assess if it could be measured using swept source optical coherence tomography (ss-OCT) technology. METHODS: All patients were measured at their pre-assessment visit 1 week prior to cataract surgery using conventional optical biometry (PCI technology, IOLMaster 500, Carl Zeiss Meditec AG, Jena, Germany)...
March 1, 2018: Ophthalmology and Therapy
Xingyi Li, Wei Wang, Wenbin Huang, Shida Chen, Jiawei Wang, Zhonghao Wang, Yaoming Liu, Mingguang He, Xiulan Zhang
PURPOSE: To measure the anterior and posterior ocular biometric characteristics concurrently and to explore the relationship between iris, ciliary body and choroid in acute primary angle closure eyes (APAC) and fellow eyes. METHODS: It is a prospective, cross-sectional study. Thirty patients with recent APAC were finally enroled in it. Anterior and posterior uveal parameters were measured simultaneously by anterior segment optical coherence tomography (AS-OCT), swept-source optical coherence tomography (SS-OCT) and ultrasound biomicroscopy (UBM)...
March 1, 2018: Eye
Noel Padrón-Pérez, Luis Arias, Marcos Rubio, Daniel Lorenzo, Pere García-Bru, Jaume Català-Mora, José M Caminal
Purpose: We evaluate changes in choroidal thickness after intravitreal injection (IVI) therapy for pachychoroid neovasculopathy (PNV). Methods: An observational, retrospective, consecutive case series was studied of 18 patients (18 eyes) who underwent anti-vascular endothelial growth factor (VEGF) therapy for PNV. The 18 fellow eyes in these patients were used as controls. All eyes were evaluated with swept-source optical coherence tomography (SS-OCT) and optical coherence tomography angiography (OCTA)...
February 1, 2018: Investigative Ophthalmology & Visual Science
Jiqiang Kang, Pingping Feng, Xiaoming Wei, Edmund Y Lam, Kevin K Tsia, Kenneth K Y Wong
A swept source with both high repetition-rate and broad bandwidth is indispensable to enable optical coherence tomography (OCT) with high imaging rate and high axial resolution. However, available swept sources are commonly either limited in speed (sub-MHz) by inertial or kinetic component, or limited in bandwidth (<100 nm) by the gain medium. Here we report an ultrafast broadband (over 100 nm centered at 1.55-µm) all-fiber inertial-free swept source built upon a high-power dispersion-managed fiber laser in conjunction with an optical time-stretch module which bypasses complex optical amplification scheme, which result in a portable and compact implementation of time-stretch OCT (TS-OCT) at A-scan rate of 44...
February 19, 2018: Optics Express
Hideo Akiyama, Danjie Li, Yukitoshi Shimoda, Hidetaka Matsumoto, Shoji Kishi
PURPOSE: To describe the relationship between the vitreous and the neovascularization of the disc (NVD) using swept source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). STUDY DESIGN: Retrospective. METHODS: We examined 17 eyes of 11 consecutive patients diagnosed as NVD associated with proliferative diabetic retinopathy (PDR). The location of the NVD feeder or collector vessels were examined by using RTVue XR Avanti. To determine the condition of the posterior vitreous detachment (PVD) and the proliferative tissue of the NVD, we performed 12 mm horizontal and vertical scans through the disc using SS-OCT...
May 2018: Japanese Journal of Ophthalmology
Swarup S Swaminathan, Fang Zheng, Andrew R Miller, Giovanni Gregori, Janet L Davis, Philip J Rosenfeld
A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
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