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human papillomavirus vaccination

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https://www.readbyqxmd.com/read/28428646/-hpv-vaccination-active-offer-in-an-italian-region
#1
Elisa Terracciano, Gian Loreto D'Alò, Silvia Aquilani, Anna Maria Aversa, Giuseppina Bartolomei, Maria Gabriella Calenda, Raffaele Catapano, Silvio Compagno, Piera Della Rovere, Angelo Fraioli, Roberto Ieraci, Daniela Reggiani, Stefano Sgricia, Antonietta Spadea, Laura Zaratti, Elisabetta Franco
Human Papillomavirus is responsible for 4.8% of cancers, and is the main cause of cervical cancer. Cervical cancer can be reduced by mean of secondary prevention (PAP-test, HPV-DNA test), while through primary prevention (anti-HPV vaccine) the incidence of other HPV-attributable cancers can also be reduced. In Italy, anti-HPV vaccination is part of the immunization schedule in girls since 2008, and in 2017 it was extended to boys. However, vaccine coverage is decreasing nationwide. This study aims to examine anti-HPV vaccination practices in Health care services of Lazio Region, Italy...
January 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28428157/texting-and-mobile-phone-app-interventions-for-improving-adherence-to-preventive-behavior-in-adolescents-a-systematic-review
#2
Sherif M Badawy, Lisa M Kuhns
BACKGROUND: Many preventable behaviors contribute to adolescent mortality and morbidity. Non-adherence to preventive measures represents a challenge and has been associated with worse health outcomes in this population. The widespread use of electronic communication technologies by adolescents, particularly the use of text messaging (short message service, SMS) and mobile phones, presents new opportunities to intervene on risk and preventive risk behavior, but little is known about their efficacy...
April 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28423693/enhanced-anti-tumor-therapeutic-efficacy-of-dna-vaccine-by-fusing-the-e7-gene-to-baff-in-treating-human-papillomavirus-associated-cancer
#3
Chao-Chih Wu, Fang-Cih Wu, Yun-Tin Hsu, Yu-Chia Hsiao, Yuh-Cheng Yang, C Allen Chang, Chih-Long Chang
B-cell-activating factor (BAFF) belongs to the tumor necrosis factor family that not only stimulates B and T cells but also counteracts immune tolerance. BAFF is also a type II membrane protein, which is secreted through the endoplasmic reticulum (ER)-Golgi apparatus pathway. Fusing an antigen to BAFF might enhance the presentation of major histocompatibility complex class I molecules. These characteristics represent an opportunity to enhance the antitumor effects of DNA vaccines. Therefore, we fused BAFF to human papillomavirus type 16 E7 as a DNA vaccine and evaluated its antitumor effects...
March 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423114/human-papillomavirus-vaccine-efficacy-in-the-prevention-of-anogenital-warts-systematic-review-and-meta-analysis
#4
Romina A Tejada, Kris G Vargas, Vicente Benites-Zapata, Edward Mezones-Holguín, Rafael Bolaños-Díaz, Adrián V Hernandez
Objective: To review evidence on the efficacy of HPV vaccines in the prevention of non-cancer lesions (anogenital warts [AGW], recurrent laryngeal papillomatosis and oral papillomatosis). Materials and methods: We conducted a systematic review of randomized trials. We performed random effect models and effects were reported as relative risks (RR) and their confidence intervals (95%CI) following both intention to treat (ITT) and per protocol (PP) analyses. Results: We included six studies (n=27 078)...
January 2017: Salud Pública de México
https://www.readbyqxmd.com/read/28420907/effectiveness-of-health-education-programme-level-of-knowledge-about-prevention-of-cervical-cancer-among-saudi-female-healthcare-students
#5
Ghadeer Khaled Al-Shaikh, Sadiqa Badar Syed, Amel Ahmed Fayed, Reem Ali Al-Shaikh, Eman Mohammed Al-Mussaed, Farida Habib Khan, Hala Nasser Elmorshedy
OBJECTIVE: To evaluate the effectiveness of health education programme on the knowledge of human papilloma virus among female medical students. METHODS: This quasi-experimental study was conducted in 2014 at the Princess Nourah bint Abulrahman University, Riyadh, Saudi Arabia, and comprised female medical students. An intervention programme was implemented in the form of lectures, videos, posters, etc. on human papillomavirus. SPSS 20 was used for data analysis...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28419156/school-nurses-attitudes-towards-and-experiences-of-the-swedish-school-based-hpv-vaccination-programme-a-repeated-cross-sectional-study
#6
Maria Grandahl, Margareta Larsson, Tanja Tydén, Christina Stenhammar
The aim was to investigate school nurses' attitudes towards, and experiences of vaccination against human papillomavirus (HPV), and compare the results with a similar study three years earlier. School nurses (n = 736) from all counties in Sweden completed a questionnaire in spring 2016, four years after the implementation of the national HPV vaccination programme, and three years after the previous survey. Overall, the school nurses had more favourable attitudes towards the HPV vaccination programme compared to the study in 2013 (p = 0...
2017: PloS One
https://www.readbyqxmd.com/read/28417212/lalf32-51-e7-therapeutic-vaccine-induces-antitumor-immunity-against-human-papillomavirus-type-16-e7-expressing-murine-tumor-metastases-in-the-lungs
#7
Milaid Granadillo, Aileen Batte, Aracelys Blanco, Alain B Alfonso, José Suárez, Nelson Merino, Rosalina Carballo, Bárbara O González, Yayrí C Prieto, Laura Varas, Dayana Soler, Miladys Limonta, Maelys Miyares, Lizet Aldana, Isis Torrens
One important goal of cancer immunotherapy is to prevent and treat tumor metastasis. We have previously reported the significant antitumor effect induced by the immunization with our human papillomavirus therapeutic protein-based vaccine (LALF32-51-E7) without adjuvant and admixed with clinically relevant adjuvants in the subcutaneous TC-1 tumor challenge model. In the present study, we evaluated the efficacy of the above mentioned vaccine formulations in controlling the hematogenous spread of TC-1 tumor cells using a more tumourigenic clone named TC-1* and other intravenous injection site less stressful than the tail vein...
April 17, 2017: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/28416242/human-papillomavirus-and-oral-squamous-cell-carcinoma-a-review-of-hpv-positive-oral-squamous-cell-carcinoma-and-possible-strategies-for-future
#8
REVIEW
Shan Jiang, Yong Dong
Oral squamous cell carcinoma (OSCC) is a common cancer worldwide. Besides tobacco use and alcohol consumption, human papillomavirus (HPV) infection has also been identified as a risk factor for OSCC recently. The OSCC incidence has increased in recent years, especially among younger women. The purpose of this article is to review clinical and epidemiological studies on the association between HPV infection and OSCCs, and the efficacy of HPV vaccine, so as to provide possible policy implications for preventing HPV-positive OSCC...
March 1, 2017: Current Problems in Cancer
https://www.readbyqxmd.com/read/28414659/knowledge-of-hpv-related-oropharyngeal-cancer-and-use-of-human-papillomavirus-vaccines-by-pediatricians-in-louisiana
#9
Vikas Mehta, Sean Holmes, Adam Master, Blake Leblanc, L Gloria Caldito, Joseph Bocchini
OBJECTIVES: To determine the level of knowledge of HPV related oropharyngeal cancer and practice patterns of HPV vaccine use by pediatricians. STUDY DESIGN, SUBJECTS, METHODS: IRB approved 18-question survey was administered to members of the Louisiana Chapter of the American Academy of Pediatrics. RESULTS: We received 116 responses (response rate: 15.9 percent );. 104 respondents (89.66 percent ); routinely recommend/offer HPV vaccine, 6 (5...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413829/prioritizing-us-cervical-cancer-prevention-with-results-from-a-geospatial-model
#10
Jonathan K Kish, Alicia I Rolin, Zhaohui Zou, James E Cucinelli, Zaria Tatalovich, Mona Saraiya, Sean F Altekruse
PURPOSE: To determine if differences in screening and vaccination patterns across the population may accentuate ethnic and geographic variation in future burden of disease. METHODS: Using Cancer in North America data provided by the North American Association of Central Cancer Registries, county cervical cancer incidence trends from 1995 to 2009 were modeled for the entire United States using ecologic covariates. Rates for health service areas were also modeled by ethnicity...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28413500/enhancement-of-humoral-and-cell-mediated-immune-response-to-hpv16-l1-derived-peptides-subsequent-to-vaccination-with-prophylactic-bivalent-hpv-l1-virus-like-particle-vaccine-in-healthy-females
#11
Masato Yokomine, Satoko Matsueda, Kouichiro Kawano, Tetsuro Sasada, Akimasa Fukui, Takuto Yamashita, Nobukazu Komatsu, Shigeki Shichijo, Kazuto Tasaki, Ken Matsukuma, Kyogo Itoh, Toshiharu Kamura, Kimio Ushijima
Currently prophylactic HPV16/18 L1 virus-like particle (VLP) vaccines are employed with great success for the prevention of HPV infection. However, limited information is available regarding the immune responses against human papillomavirus (HPV) 16/18 L1 subsequent to HPV16/18 L1 VLP vaccination, primarily due to the lack of widely used assays for immune monitoring. The aim of the present study was to identify HPV16 L1-derived B and T cell epitopes for monitoring the immune responses after HPV16/18 L1 VLP vaccination in healthy females...
April 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28410863/-human-papillomaviruses-vaccination-parental-awareness-and-acceptance-of-the-vaccine-for-children-in-lower-normandy-schools-and-informative-campaign-during-the-2015-2016%C3%A2-school-year
#12
S Eve, A-D Pham, X Blaizot, M Turck, T Raginel
BACKGROUND: The vaccine against human papillomavirus (HPV) can be administered starting at the age of 9 years. Parents thus play a major role in the choice of vaccination. The objective of this study was to investigate parental awareness about anti-HPV vaccination in Lower Normandy and to measure their vaccinal intentions before an informative campaign. METHODS: The study population included parents of children aged 10-11 years enrolled in school (2015-2016) in Lower Normandy, France...
April 12, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28408119/ecological-validity-of-cost-effectiveness-models-of-universal-hpv-vaccination-a-systematic-literature-review
#13
REVIEW
Giampiero Favato, Tania Easton, Riccardo Vecchiato, Emmanouil Noikokyris
BACKGROUND: The protective (herd) effect of the selective vaccination of pubertal girls against human papillomavirus (HPV) implies a high probability that one of the two partners involved in intercourse is immunised, hence preventing the other from this sexually transmitted infection. The dynamic transmission models used to inform immunisation policy should include consideration of sexual behaviours and population mixing in order to demonstrate an ecological validity, whereby the scenarios modelled remain faithful to the real-life social and cultural context...
April 10, 2017: Vaccine
https://www.readbyqxmd.com/read/28407312/nasopharyngeal-papillomas-treated-with-co2-laser-and-human-papillomavirus-vaccination
#14
Yi Cai, Valeria S Merea, Andrew H Lee, Gloria H Su, Salvatore M Caruana
This case report describes the use of CO2 laser and quadrivalent human papillomavirus (HPV) vaccination in two patients with nasopharyngeal HPV11-positive recurrent respiratory papillomas (RRP). These patients initially underwent CO2 laser excision but developed recurrent lesions and underwent HPV vaccination as adjunct therapy. The recurrent lesions shrank after vaccination and were again excised with CO2 laser. Subsequently, these patients had no recurrence of lesions on long-term follow-up at 33 months or 6 years after surgery...
April 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28406406/cervical-cancer-in-sub-saharan-africa-an-emerging-and-preventable-disease-associated-with-oncogenic-human-papillomavirus
#15
R S Mboumba Bouassa, T Prazuck, T Lethu, J F Meye, L Bélec
Highly oncogenic human papillomavirus (HPV) infections are responsible for 7.7 % of cancers in developing countries, mainly cervical cancer. The incidence of this emerging cancer is steadily increasing in sub-Saharan Africa, with more than 75,000 new cases and close to 50,000 deaths a year, a toll further increased by HIV infection. According to the World Health Organization, cervical cancer will kill more than 443,000 women per year worldwide by 2030, nearly 90 % of them in sub-Saharan Africa. This increase in cervical cancer incidence in Africa is now counteracting the progress made by African women in reducing maternal mortality and increasing longevity...
February 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28404529/cervical-cancer-human-papillomavirus-and-vaccines-assessment-of-the-information-retrieved-from-general-knowledge-websites-in-chile
#16
C S Lopez, E Krauskopf, C E Villota, L O Burzio, J E Villegas
OBJECTIVES: Cervical cancer is the most common gynaecologic malignancy worldwide and is the sixth cause of cancer death in Chile. Human papillomavirus (HPV) is responsible for most cervical cancers. Individuals seeking basic information about HPV frequently turn to health information websites. We hypothesized that some of their data may be inaccurate. STUDY DESIGN: Comparative analysis of information. METHODS: We analyze the content of highly accessed websites such as the Spanish version of Wikipedia and Yahoo Answers through the application of a questionnaire, as well as a website managed by the Chilean Ministry of Health (Minsal)...
April 3, 2017: Public Health
https://www.readbyqxmd.com/read/28404501/development-and-validation-of-measures-to-evaluate-adolescents-knowledge-about-human-papillomavirus-hpv-involvement-in-hpv-vaccine-decision-making-self-efficacy-to-receive-the-vaccine-and-fear-and-anxiety
#17
A S Forster, K A McBride, C Davies, T Stoney, H Marshall, K McGeechan, S C Cooper, S R Skinner
OBJECTIVES: We describe the development and validation of measures of human papillomavirus (HPV)/HPV vaccination knowledge, fear/anxiety about vaccination, involvement in HPV vaccine decision-making, and self-efficacy with regard to getting the vaccine, designed to evaluate the efficacy of an intervention to affect these domains (collectively termed the HAVIQ: HPV Adolescent Vaccine Intervention Questionnaire). STUDY DESIGN: Literature search, cognitive interviews and cross-sectional survey...
March 18, 2017: Public Health
https://www.readbyqxmd.com/read/28403727/high-risk-human-papillomavirus-types-in-hiv-infected-and-hiv-uninfected-young-women-in-kwazulu-natal-south-africa-implications-for-vaccination
#18
Joyce N Mbatha, Myra Taylor, Elisabeth Kleppa, Kristine Lillebo, Hashini N Galapaththi-Arachchige, Deepak Singh, Eyrun F Kjetland, Marc F D Baay, Zilungile L Mkhize-Kwitshana
BACKGROUND: High-risk human papillomavirus (hr-HPV) infections and low-grade squamous intraepithelial lesions occur frequently in young women. The available vaccines cover up to seven hr-HPV genotypes (HPV16, HPV18, HPV31, HPV33, HPV45, HPV52 and HPV58) and two low-risk HPV types (HPV6 and HPV11). The objective of this study was to describe the hr-HPV genotypes present among HIV-uninfected and HIV-infected young women in rural high schools. METHODS: Cervicovaginal lavages were obtained from sexually active young women recruited from high schools in KwaZulu-Natal (n = 1223)...
April 12, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28402260/dna-plasmid-vaccine-carrying-chlamydia-trachomatis-ct-major-outer-membrane-and-human-papillomavirus-16l2-proteins-for-anti-ct-infection
#19
Ledan Wang, Yiqi Cai, Yirong Xiong, Wangqi Du, Danwei Cen, Chanqiong Zhang, Yiling Song, Shanli Zhu, Xiangyang Xue, Lifang Zhang
Chlamydia trachomatis (Ct) is one of the most frequently encountered sexual infection all over the world, yielding tremendous reproductive problems (e.g. infertility and ectopic pregnancy) in the women. This work described the design of a plasmid vaccine that protect mice from Ct infection, and reduce productive tract damage by generating effective antibody and cytotoxic T cell immunity. The vaccine, s was composed of MOMP multi-epitope and HPV16L2 genes carried in pcDNA plasmid (i.e. pcDNA3.1/MOMP/HPV16L)...
March 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28400857/estimation-of-the-overall-burden-of-cancers-precancerous-lesions-and-genital-warts-attributable-to-9-valent-hpv-vaccine-types-in-women-and-men-in-europe
#20
Susanne Hartwig, Jean Lacau St Guily, Géraldine Dominiak-Felden, Laia Alemany, Silvia de Sanjosé
BACKGROUND: In addition to cervical cancer, human papillomavirus (HPV) is responsible for a significant proportion of cancers and precancerous lesions of the vulva, vagina, anus, penis, head and neck, as well as genital warts. We estimated the annual number of new cases of these diseases attributable to 9-valent HPV vaccine types in women and men in Europe. METHODS: The annual number of new cancers of the cervix, vulva, vagina, anus, penis, and selected head and neck sites in the population of the European Medicines Agency territory was estimated based on age-specific incidence rates extracted from Cancer Incidence in 5 Continents, Volume X and Eurostat population data for 2015...
2017: Infectious Agents and Cancer
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