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human papillomavirus vaccination

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https://www.readbyqxmd.com/read/29458181/hospitalization-burden-associated-with-malignant-neoplasia-and-in-situ-carcinoma-in-vulva-and-vagina-during-a-5-year-period-2009-2013-in-spain-an-epidemiological-study
#1
Noelia López, Ángel Gil-de-Miguel, Raquel Pascual-García, Jose Manuel Ramón Y Cajal, Ruth Gil-Prieto
BACKGROUND: Vulvar and vaginal cancers are considered rare cancers in women. Human Papillomavirus is responsible for 30%-76% of them. The aim of this study was to describe the burden of hospital admissions by malignant neoplasia (MN) and in situ carcinoma (ISC) of vulva and vagina from 2009 to 2013, in Spain METHODS: This observational, descriptive study used discharge information obtained from the national surveillance system for hospital data, Conjunto Mínimo Básico de Datos, CMBD, provided by the Ministry of Health...
February 16, 2018: Papillomavirus Research
https://www.readbyqxmd.com/read/29454382/high-risk-human-papillomavirus-prevalence-and-genotype-distribution-among-women-infected-with-hiv-in-manaus-amazonas
#2
Monique Figueiredo Teixeira, Meritxell Sabidó, André Luiz Leturiondo, Cynthia de Oliveira Ferreira, Kátia Luz Torres, Adele Schwartz Benzaken
BACKGROUND: Human immunodeficiency virus (HIV)-positive women have a high prevalence of human papillomavirus (HPV), and are infected with a broader range of HPV types than HIV-negative women. We aimed to determine the prevalence of cervical cytologic abnormalities, high-risk (HR)-HPV prevalence, type distribution according to the severity of cervical lesions and CD4 cell count and identify factors associated with HR-HPV infection among women living with HIV in Manaus, Amazonas. METHODS: We enrolled 325 women living with HIV that attended an infectious diseases referral hospital...
February 17, 2018: Virology Journal
https://www.readbyqxmd.com/read/29453187/quality-of-web-based-educational-interventions-for-clinicians-on-human-papillomavirus-vaccine-content-and-usability-assessment
#3
Brittany L Rosen, James M Bishop, Skye L McDonald, Jessica A Kahn, Gary L Kreps
BACKGROUND: Human papillomavirus (HPV) vaccination rates fall far short of Healthy People 2020 objectives. A leading reason is that clinicians do not recommend the vaccine consistently and strongly to girls and boys in the age group recommended for vaccination. Although Web-based HPV vaccine educational interventions for clinicians have been created to promote vaccination recommendations, rigorous evaluations of these interventions have not been conducted. Such evaluations are important to maximize the efficacy of educational interventions in promoting clinician recommendations for HPV vaccination...
February 16, 2018: JMIR Cancer
https://www.readbyqxmd.com/read/29452366/prevalence-and-incidence-of-anal-and-cervical-high-risk-human-papillomavirus-hpv-types-covered-by-current-hpv-vaccines-among-hiv-infected-women-in-the-study-to-understand-the-natural-history-of-hiv-aids-in-the-era-of-effective-therapy-the-sun-study
#4
Erna Milunka Kojic, Lois Conley, Tim Bush, Susan Cu-Uvin, Elizabeth R Unger, Keith Henry, John Hammer, Gerome Escota, Teresa M Darragh, Joel M Palefsky, John T Brooks, Pragna Patel
Background: Nonavalent (9v) human papilloma virus vaccine targets high-risk (HR)-HPV types 16, 18, 31, 33, 45, 52, 58, and low-risk 6, 11. We examined prevalence, incidence, and clearance of anal and cervical HR-HPV in HIV-infected women. Methods: From 2004-2006, the SUN Study enrolled 167 women from four US cities. Anal and cervical specimens were collected annually for cytology and identification of 37 HPV types; 14 HR include: 9v 16, 18, 31, 33, 45, 52, 58; non-9v 35, 39, 51, 56, 59, 66, 68...
February 14, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29447271/parents-knowledge-beliefs-and-acceptance-of-the-hpv-vaccination-in-relation-to-their-socio-demographics-and-religious-beliefs-a-cross-sectional-study-in-thailand
#5
Maria Grandahl, Seung Chun Paek, Siriwan Grisurapong, Penchan Sherer, Tanja Tydén, Pranee Lundberg
Thailand has one of the world's highest prevalence of cervical cancer, mainly caused by the human papillomavirus (HPV). HPV infections can successfully be prevented by vaccination, which is available at a cost but not yet implemented in the national vaccination program. Parents play a critical role in deciding whether to vaccinate their child against HPV. Thus, the aim was to examine the association between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs...
2018: PloS One
https://www.readbyqxmd.com/read/29446090/potential-lives-saved-in-73-countries-by-adopting-multi-cohort-vaccination-of-9-14-year-old-girls-against-human-papillomavirus
#6
Mark Jit, Marc Brisson
Up to 2016, low- and middle-income countries mostly introduced routine human papillomavirus (HPV) vaccination for just a single age-cohort of girls each year. However, high income countries have reported large reductions in HPV prevalence following "catch-up" vaccination of multiple age-cohorts in the year of HPV vaccine introduction. We used the mathematical model PRIME to project the incremental impact of vaccinating 10-14-year old girls compared to routine HPV vaccination only in the same year that routine vaccination is expected to be introduced for 9-year old girls across 73 low and lower-middle income countries...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29445898/knowledge-attitudes-and-barriers-to-human-papillomavirus-hpv-vaccine-uptake-among-an-immigrant-and-refugee-catch-up-group-in-a-western-canadian-province
#7
Erin McComb, Vivian Ramsden, Olufemi Olatunbosun, Hazel Williams-Roberts
Vaccination is a key strategy to prevent cervical cancer in developed countries. Lower uptake of human papillomavirus (HPV) vaccine among new immigrants and refugees has been documented, although exploration of underlying reasons remains an understudied area. Semi-structured interviews with eleven immigrant women (ages 18-26 years) were conducted to understand their knowledge, attitudes and barriers regarding HPV vaccination in a western Canadian province. Participants had limited knowledge about HPV and the vaccine...
February 14, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29442400/what-information-can-change-the-attitude-of-teachers-toward-the-human-papillomavirus-vaccine
#8
Masaharu Kamada, Hiroaki Inui, Tomohiro Kagawa, Ayuka Mineda, Takao Tamura, Tomohito Fujioka, Takahiro Motoki, Hiroki Hirai, Eiichi Ishii, Minoru Irahara
AIM: We conducted a self-administered survey on the perception of teachers toward human papillomavirus (HPV) vaccine to determine the ways to increase their willingness to encourage its use. METHODS: Answers were obtained both prior to and after having the teachers read five brief information articles: (i) cervical cancer knowledge, (ii) vaccine knowledge, (iii) result of a survey in Nagoya, (iv) news report of the World Health Organization statement and (v) articles written by Dr Muranaka, a journalist...
February 14, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29439180/secondary-neoplasms-of-the-female-lower-genital-tract-after-hematopoietic-cell-transplantation
#9
REVIEW
Howard A Chang, Saro H Armenian, Thanh H Dellinger
Hematopoietic cell transplantation (HCT) results in long-term survival (≥10 years) in 85% of patients who survive transplant-related complications within the first 2 years posttransplant. Transplant survivors, however, are at an increased risk of chronic health conditions compared with the general population, including the emergence of secondary malignant neoplasms. In particular, female transplant survivors may face a greater risk of lower genital tract (cervical, vulvar, or vaginal) neoplasms due to chronic immune dysregulation in the peritransplant and posttransplant environment...
February 2018: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29435283/targeted-immunotherapy-of-high-grade-cervical-intra-epithelial-neoplasia-expectations-from-clinical-trials
#10
Jean-Luc Brun, José Rajaonarison, Nicolas Nocart, Laura Hoarau, Stéphanie Brun, Isabelle Garrigue
Targeted immunotherapy of high-grade cervical intra-epithelial neoplasia (CIN) has been developed as an alternative to conization, to preserve future reproductive outcomes and avoid human papillomavirus (HPV) persistence. The objectives of the review are to present drugs according to their process of development and to examine their potential future use. A search for key words associated with CIN and targeted immunotherapy was carried out in the Cochrane library, Pubmed, Embase, and ClinicalTrials.gov from 1990 to 2016...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29433017/continuing-global-improvement-in-human-papillomavirus-dna-genotyping-services-the-2013-and-2014-hpv-labnet-international-proficiency-studies
#11
Carina Eklund, Ola Forslund, Keng-Ling Wallin, Joakim Dillner
BACKGROUND: Accurate and internationally comparable human papillomavirus (HPV) DNA detection and typing services are essential for HPV vaccine research and surveillance. OBJECTIVES: This study assessed the proficiency of different HPV typing services offered routinely in laboratories worldwide. STUDY DESIGN: The HPV Laboratory Network (LabNet) has designed international proficiency panels that can be regularly issued. The HPV genotyping proficiency panels of 2013 and 2014 contained 43 and 41 coded samples, respectively, composed of purified plasmids of sixteen HPV types (HPV 6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68a and 68b) and 3 extraction controls...
February 9, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29428178/evaluation-on-the-persistence-of-anti-hpv-immune-responses-to-the-quadrivalent-hpv-vaccine-in-chinese-females-and-males-up-to-3-5%C3%A2-years-of-follow-up
#12
Teng Huang, Youping Liu, Yanping Li, Yuqin Liao, Qiong Shou, Minghuan Zheng, Xueyan Liao, Rongcheng Li
BACKGROUND: This was an extension study of a randomized, double-blind, placebo-controlled immunogenicity and safety study of the quadrivalent human papillomavirus (qHPV) (HPV 6, 11, 16, and 18) vaccine conducted in Chinese female subjects aged 9-45 years and male subjects aged 9-15 years. To investigate the persistence of anti-HPV 6, -11, -16, and -18 responses among Chinese subjects, subjects enrolled in the base study were followed up at around month 42 (approximately 3.5 years after vaccination)...
February 7, 2018: Vaccine
https://www.readbyqxmd.com/read/29428177/caregiver-and-adolescent-factors-associated-with-delayed-completion-of-the-three-dose-human-papillomavirus-vaccination-series
#13
Lea E Widdice, Rebecca Hoagland, S Todd Callahan, Jessica A Kahn, Christopher J Harrison, Barbara A Pahud, Sharon E Frey, Andrea A Berry, Karen L Kotloff, Kathryn M Edwards, Mark J Mulligan, Jon Sudman, Aya Nakamura, David I Bernstein
BACKGROUND: Delayed completion of human papillomavirus vaccination (4vHPV) series is common. We sought to identify factors associated with delay. METHODS: This substudy was part of a large prospective, multi-site study recruiting 9-17 year old girls at the time of their third 4vHPV dose to assess immunogenicity associated with prolonged dosing intervals. At participating sites, parents/legal guardians (caregivers) of all enrolled girls (9-17 years old) and enrolled girls aged 14-17 years were approached for participation...
February 7, 2018: Vaccine
https://www.readbyqxmd.com/read/29425361/quadrivalent-human-papillomavirus-vaccination-in-boys-and-risk-of-autoimmune-diseases-neurological-diseases-and-venous-thromboembolism
#14
Morten Frisch, Andréa Besson, Kim Katrine Bjerring Clemmensen, Palle Valentiner-Branth, Kåre Mølbak, Anders Hviid
Background: In recent years, human papillomavirus (HPV) vaccination of boys has been added to childhood vaccination programmes in several countries but, so far, no systematic population-based assessment with long-term follow-up has been undertaken of the relative incidence of adverse outcomes following HPV vaccination in this group. We investigated if quadrivalent HPV (qHPV) vaccination of 10-17-year-old boys is associated with any unusual risk of autoimmune diseases, neurological diseases or venous thromboembolism...
February 7, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29425358/very-low-prevalence-of-vaccine-human-papillomavirus-hpv-types-among-18-to-35-year-old-australian-women-nine-years-following-implementation-of-vaccination
#15
Dorothy A Machalek, Suzanne M Garland, Julia M L Brotherton, Deborah Bateson, Kathleen McNamee, Mary Stewart, S Rachel Skinner, Bette Liu, Alyssa M Cornall, John M Kaldor, Sepehr N Tabrizi
Introduction: A quadrivalent human papillomavirus vaccination program targeting females aged 12-13 commenced in Australia in 2007, with catch-up vaccination of 14-26 year olds through 2009. We evaluated the program's impact on HPV prevalence among women aged 18-35 in 2015. Methods: HPV prevalence among women aged 18-24 and 25-35 was compared with prevalence among women in these age groups in 2005-2007. For women aged 18-24, we also compared prevalence with that in a post-vaccine study conducted in 2010-2012...
February 7, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29424799/safety-and-immunogenicity-of-the-hpv-16-18-as04-adjuvanted-vaccine-in-4-6-year-old-girls-results-to-month-12-from-a-randomized-trial
#16
Lan Lin, Mercedes Macias Parra, Victor Y Sierra, Albino Salas Cespedes, Maria Angelica Granados, Adriana Luque, Silvia Damaso, Maria Mercedes Castrejon Alba, Luis Romano-Mazzotti, Frank Struyf
BACKGROUND: The burden of cervical cancer caused by human papillomavirus (HPV) is high in Latin America. The suboptimal HPV vaccination coverage in adolescents could be improved by pediatric immunization. HPV vaccination has not yet been reported in girls aged <9 years. METHODS: This ongoing phase III, controlled, randomized, single-blind, multicenter study conducted in Colombia, Mexico and Panama (NCT01627561) evaluated the safety and immunogenicity of AS04-HPV-16/18 vaccine in 4-6-year-old girls...
February 7, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29424778/persistence-of-memory-b-cell-and-t-cell-responses-to-the-quadrivalent-hpv-vaccine-in-hiv-infected-children
#17
Adriana Weinberg, Sharon Huang, A B Moscicki, Afred Saah, Myron J Levin
OBJECTIVE: To determine the magnitude and persistence of quadrivalent human papillomavirus (HPV)16 and HPV18 B-cell and T-cell memory after three or four doses of quadrivalent HPV vaccine (QHPV) in HIV-infected children. METHODS: Seventy-four HIV-infected children immunized with four doses and 23 with three doses of QHPV had HPV16 and HPV18 IgG B-cell and IFNγ and IL2 T-cell ELISPOT performed at 2, 3.5 and 4-5 years after the last dose. RESULTS: HPV16 and HPV18 T-cell responses were similar in both treatment groups, with higher responses to HPV16 vs...
February 8, 2018: AIDS
https://www.readbyqxmd.com/read/29416557/prevalence-of-human-papillomavirus-infection-among-iranian-women-using-cobas-hpv-dna-testing
#18
Farzane Jamdar, Farah Farzaneh, Fariba Navidpour, Sarang Younesi, Payam Balvayeh, Maryamsadat Hosseini, Robabeh Ghodssi-Ghasemabadi
Background: Persistent infection with High Risk Human Papillomavirus (HR HPV) typesplaysamajor role in the development of cervical cancer. Therefore, the detection of HR HPV types is an essential part of cervical cancer screening. The aim of this study was to estimate the prevalence of HR HPV infection among healthy women undergoing routine cervical cancer screening in Iran. Methods: In this cross-sectional study,the results of HPV DNA typing in 2453 normal Iranian womenwhowere referred for routine cervical cancer screening from September 2015 to March 2017 were analyzed...
2018: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29414659/evaluation-of-immune-responses-induced-by-a-novel-human-papillomavirus-type-16-e7-peptide-based-vaccine-with-candida-skin-test-reagent-as-an-adjuvant-in-c57bl-6-mice
#19
Xingxuan Wang, Yuxin Che, Bingnan Chen, Yao Zhang, Mayumi Nakagawa, Xuelian Wang
Cell mediated immune (CMI) responses are crucial for the clearance of human papillomavirus (HPV) infection and HPV-associated lesions. Activated CD8 T cells are critical effector cells in recognizing and killing HPV-infected or HPV-transformed cells. CD4 T cells provide help for priming the generation and maintenance of CD8 T cells as well as for tumors immunity. An ideal therapeutic HPV peptide-based vaccine should induce both a robust CD8 T-cell response as well as a CD4 T-cell response for ensuring their efficiency...
January 30, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29412771/human-papillomavirus-vaccine-awareness-among-hiv-positive-gay-and-bisexual-men-a-qualitative-study
#20
Alexis M Koskan, Madeline Fernández-Pineda
PURPOSE: This study explores HIV-positive gay and bisexual men's (GBM) understanding of human papillomavirus (HPV) and the HPV vaccine. METHODS: Researchers conducted 15 in-depth interviews with HIV-positive GBM between the ages of 18-30 years old. RESULTS: Two participants had received a single dose of the HPV vaccine. Otherwise, the majority of participants had either never heard of the HPV vaccine or they perceived it as a resource for women only...
February 7, 2018: LGBT Health
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