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human papillomavirus vaccination

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https://www.readbyqxmd.com/read/29224043/identification-of-human-papillomavirus-hpv-subtype-in-oral-cancer-patients-through-microarray-technology
#1
Soung Min Kim, Ik Jae Kwon, Hoon Myoung, Jong Ho Lee, Suk Keun Lee
PURPOSE: Human papilloma virus (HPV) is the main source of cervical cancer. Many recent studies have revealed the prevalence and prognosis of HPV associated with oropharyngeal squamous cell carcinoma, but fewer reports have evaluated HPV in oral squamous cell carcinoma (OSCC). The purpose of this study was to determine the prevalence and prognosis of HPV associated with OSCC according to HPV and tumor types. MATERIALS AND METHODS: We used a DNA chip kit (MY-HPV chip kit ®, Mygene Co...
December 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29222179/hpv-vaccination-rate-in-french-adolescent-girls-an-example-of-vaccine-distrust
#2
Hervé Lefèvre, Cécile Schrimpf, Marie Rose Moro, Jonathan Lachal
OBJECTIVES: To explore the clinical issues of human papillomavirus (HPV) vaccination to develop explanatory hypotheses for the low level of vaccination among adolescent girls in France where the full course coverage is low (<15%). DESIGN: We used semistructured interviews. Our qualitative and phenomenological procedure applied interpretative phenomenological analysis. PARTICIPANTS: 16 physicians regularly faced with the prescription of HPV vaccine, represented several medical specialties (paediatrics, general practice, internal medicine, gynaecology), with hospitalist or private practices...
December 8, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29221217/the-association-between-human-papillomavirus-infection-and-lung-cancer-a-system-review-and-meta-analysis
#3
Wei-Min Xiong, Qiu-Ping Xu, Xu Li, Ren-Dong Xiao, Lin Cai, Fei He
To estimate the global attributable fraction of human papillomavirus (HPV) in lung cancer, we provided updated information through a system review and meta-analysis. We did a literature search on PubMed, Ovid and Web of Science to identify case-control studies and cohort studies that detected HPV in lung carcinomas. We included studies that tested 30 or more cases and were published before Feb 28, 2017. We collected information about gender, smoking status, HPV detection methods, HPV types, materials and clinical features...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29216355/prevalence-of-and-risk-factors-for-anal-hpv-among-a-sample-of-predominantly-black-men-who-have-sex-with-men-in-houston-texas
#4
Alan G Nyitray, Kayo Fujimoto, Jing Zhao, Anna R Giuliano, John A Schneider, Lu-Yu Hwang
Introduction: Young men who have sex with men (MSM) are at increased risk for human papillomavirus (HPV)-associated disease as a result of HPV infection. Our objective was to characterize high-risk anal HPV prevalence, and factors associated with prevalence, among a group of young, primarily black, MSM in Houston, Texas. Background: Young MSM, aged 18-29 years, were recruited using a respondent-driven sampling method to study HIV/STD transmission and risk. The current analysis estimated HPV prevalence among 135 primarily young black MSM who engaged in peer recruitment chains and who self-collected anal exfoliated cells...
December 5, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29214413/new-cancer-cases-in-france-in-2015-attributable-to-infectious-agents-a-systematic-review-and-meta-analysis
#5
Kevin David Shield, Claire Marant Micallef, Catherine de Martel, Isabelle Heard, Francis Megraud, Martyn Plummer, Jérôme Vignat, Freddie Bray, Isabelle Soerjomataram
To provide an assessment of the burden of cancer in France in 2015 attributable to infectious agents. A systematic literature review in French representative cancer cases series was undertaken of the prevalence of infectious agents with the major associated cancer types. PubMed was searched for original studies published up to September 2016; random-effects meta-analyses were performed. Cancer incidence data were obtained from the French Cancer Registries Network, thereby allowing the calculation of national incidence estimates...
December 6, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29212932/minor-capsid-protein-l2-polytope-induces-broad-protection-against-oncogenic-and-mucosal-human-papillomaviruses
#6
Somayeh Pouyanfard, Gloria Spagnoli, Lorenzo Bulli, Kathrin Balz, Fan Yang, Caroline Odenwald, Hanna Seitz, Filipe C Mariz, Angelo Bolchi, Simone Ottonello, Martin Müller
The amino terminus of the human papillomavirus minor capsid protein L2 contains a major cross-neutralization epitope which provides the basis for the development of a broadly protecting HPV vaccine. Wide range of protection against different HPV types would eliminate one of the major drawbacks of the commercial, L1 based prophylactic vaccines. Previously, we have reported that insertion of the L2 epitope into a scaffold composed of bacterial thioredoxin protein generates a potent antigen inducing comprehensive protection against different animal and human papillomaviruses...
December 6, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29211620/safety-profile-of-the-9-valent-human-papillomavirus-vaccine-assessment-in-prior-quadrivalent-hpv-vaccine-recipients-and-in-men-16-to-26%C3%A2-years-of-age
#7
E D Moreira, A R Giuliano, J de Hoon, O-E Iversen, E A Joura, J Restrepo, P Van Damme, C Vandermeulen, M C Ellison, A Krick, C Shields, B Heiles, A Luxembourg
A 9-valent HPV (9vHPV) vaccine has been developed to protect against HPV type 6/11/16/18/31/33/45/52/58-related infection and disease. Previous safety analyses from 7 clinical trials conducted in 9vHPV vaccine recipients 9-26 years of age, including comparisons of 9vHPV and quadrivalent HPV (qHPV) vaccines in girls and women 16-26 years of age, showed that the 9vHPV vaccine was generally well tolerated. Additional safety analyses were conducted to include the results of new clinical studies. The safety profile of the 9vHPV vaccine in prior qHPV vaccine recipients (n=3756 from 1 randomized controlled trial and 2 open-label extension studies) and young men (n=248 9vHPV and n=248 qHPV vaccine recipients from 1 randomized controlled trial) was evaluated...
December 6, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29211035/high-resolution-structure-analysis-of-antibody-v5-and-u4-conformational-epitopes-on-human-papillomavirus-16
#8
Jian Guan, Stephanie M Bywaters, Sarah A Brendle, Robert E Ashley, Alexander M Makhov, James F Conway, Neil D Christensen, Susan Hafenstein
Cancers attributable to human papillomavirus (HPV) place a huge burden on the health of both men and women. The current commercial vaccines are genotype specific and provide little therapeutic benefit to patients with existing HPV infections. Identifying the conformational epitopes on the virus capsid supports the development of improved recombinant vaccines to maximize long-term protection against multiple types of HPV. Fragments of antibody (Fab) digested from the neutralizing monoclonal antibodies H16.V5 (V5) and H16...
December 6, 2017: Viruses
https://www.readbyqxmd.com/read/29210616/mothers-willingness-to-pay-for-daughters-hpv-vaccine-in-northern-vietnam
#9
Ha Dinh Thu, Huong Nguyen Thanh, Thuy Hua Thanh, Le Nguyen Hai, Van Tran Thi, Nguyen Manh Tri, Anne Buvé
HPV vaccine is effective in preventing Human papillomavirus, the main cause of cervical cancer. In Vietnam, at first, it was subsidized at $5░a dose and reached the coverage of 96% in 2 pilot provinces, indicating potentially high acceptance. Currently, it is provided at $120-195 for three doses. This is a cross-sectional study, conducted in two northern rural districts of Vietnam. Researchers present findings to show 53.1% of mothers stated their willingness to pay (WTP) for HPV vaccine for their daughters...
December 6, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29210158/screening-for-human-papillomavirus-cervical-cytological-abnormalities-and-associated-risk-factors-in-hiv-positive-and-hiv-negative-women-in-rwanda
#10
M F Mukanyangezi, V Sengpiel, O Manzi, G Tobin, S Rulisa, E Bienvenu, D Giglio
OBJECTIVES: Cervical cancer is the major cause of death from cancer in Africa. We wanted to assess the prevalence of human papillomavirus (HPV) infections and associated risk factors and to determine whether HPV testing could serve as a screening method for squamous intraepithelial lesions (SILs) in Rwanda. We also wanted to obtain a broader understanding of the underlying risk factors for the establishment of HPV infection in Rwanda. METHODS: A total of 206 HIV-positive women, 172 HIV-negative women and 22 women with unknown HIV status were recruited at the University Teaching Hospitals of Kigali (UTHK) and of Butare (UTHB) in Rwanda...
December 6, 2017: HIV Medicine
https://www.readbyqxmd.com/read/29208707/recurring-infection-with-ecologically-distinct-hpv-types-can-explain-high-prevalence-and-diversity
#11
Sylvia L Ranjeva, Edward B Baskerville, Vanja Dukic, Luisa L Villa, Eduardo Lazcano-Ponce, Anna R Giuliano, Greg Dwyer, Sarah Cobey
The high prevalence of human papillomavirus (HPV), the most common sexually transmitted infection, arises from the coexistence of over 200 genetically distinct types. Accurately predicting the impact of vaccines that target multiple types requires understanding the factors that determine HPV diversity. The diversity of many pathogens is driven by type-specific or "homologous" immunity, which promotes the spread of variants to which hosts have little immunity. To test for homologous immunity and to identify mechanisms determining HPV transmission, we fitted nonlinear mechanistic models to longitudinal data on genital infections in unvaccinated men...
December 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29208043/self-sampling-for-human-papillomavirus-testing-among-rural-young-women-of-kwazulu-natal-south-africa
#12
J N Mbatha, H N Galapaththi-Arachchige, A Mtshali, M Taylor, P D Ndhlovu, E F Kjetland, M F D Baay, Z L Mkhize-Kwitshana
BACKGROUND: Cervical cancer is a major problem in women and it is important to find a suitable and acceptable screening method, especially among young in low-resource areas for future human papillomavirus (HPV) vaccine follow-up investigations. The study sought to test the acceptability of self-sampling as well as the suitability of the specimen collecting devices. METHODS: Ninety-eight young women from rural KwaZulu-Natal were enrolled between March and July 2014...
December 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29204462/human-papillomavirus-vaccine-sources-of-information-and-adolescents-knowledge-and-perceptions
#13
Brittany L Rosen, Marcia L Shew, Gregory D Zimet, Lili Ding, Tanya L K Mullins, Jessica A Kahn
Understanding where adolescents obtain information about human papillomavirus (HPV) vaccines may be helpful in designing public health interventions promoting HPV vaccination. This study assessed the following: (1) exposure to specific sources of information about HPV vaccines, (2) self-reported helpfulness of these sources of information, and (3) whether the specific source of information was associated with knowledge and perceptions about HPV vaccines among adolescent girls. There were 339 adolescent girls (mean age = 16...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29198916/anxiety-related-adverse-events-following-immunization-aefi-a-systematic-review-of-published-clusters-of-illness
#14
Anagha Loharikar, Tiffany A Suragh, Noni E MacDonald, Madhava R Balakrishnan, Oleg Benes, Smaragda Lamprianou, Terri B Hyde, Michael M McNeil
BACKGROUND: Clusters of anxiety-related adverse events following immunization (AEFI) have been observed in several countries and have disrupted country immunization programs. We conducted a systematic literature review to characterize these clusters, to generate prevention and management guidance for countries. METHODS: We searched seven peer-reviewed databases for English language reports of anxiety-related AEFI clusters (≥2 persons) with pre-specified keywords across 4 categories: symptom term, cluster term, vaccine term, and cluster AEFI phenomenon term/phrase...
November 29, 2017: Vaccine
https://www.readbyqxmd.com/read/29198772/human-papillomavirus-vaccine-related-risk-perceptions-do-not-predict-sexual-initiation-among-young-women-over-30-months-following-vaccination
#15
Tanya L Kowalczyk Mullins, Susan L Rosenthal, Gregory D Zimet, Lili Ding, Charlene Morrow, Bin Huang, Jessica A Kahn
PURPOSE: We examined longitudinally the relationship between human papillomavirus (HPV) vaccine-related risk perceptions and initiation of sexual activity among adolescent women over 30 months after HPV vaccination. METHODS: Participants included 91 sexually inexperienced women aged 13-21 years receiving the HPV vaccine who completed at least three of five study visits. At every visit, participants completed surveys assessing HPV vaccine-related risk perceptions (perceived risk of sexually transmitted infections [STIs] other than HPV, perceived need for safer sexual behaviors), and sexual initiation...
December 1, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29195632/parents-involvement-in-the-human-papillomavirus-vaccination-decision-for-their-sons
#16
Samara Perez, Hannah Restle, Anila Naz, Ovidiu Tatar, Gilla K Shapiro, Zeev Rosberger
OBJECTIVES: Parents are critical to ensure sufficient human papillomavirus (HPV) vaccine coverage. No studies to date have examined how mothers and fathers perceive their own, their partners' and their sons' involvement in HPV vaccination decision-making process. METHODS: An online survey methodology was used to collect data from a national sample of Canadian parents (33% fathers, 67% mothers, Mage=44) who had a 9-16years old son (n=3117). MAIN OUTCOME MEASURES: Parent's perception of their self-involvement, partner-involvement and son's involvement in the decision to get their son the HPV vaccine were measured on a Likert scale and were classified as 'no involvement', 'moderate involvement' and 'high involvement'...
December 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/29193231/using-mri-cell-tracking-to-monitor-immune-cell-recruitment-in-response-to-a-peptide-based-cancer-vaccine
#17
Marie-Laurence Tremblay, Christa Davis, Chris V Bowen, Olivia Stanley, Cathryn Parsons, Genevieve Weir, Mohan Karkada, Marianne M Stanford, Kimberly D Brewer
PURPOSE: MRI cell tracking can be used to monitor immune cells involved in the immunotherapy response, providing insight into the mechanism of action, temporal progression of tumor growth, and individual potency of therapies. To evaluate whether MRI could be used to track immune cell populations in response to immunotherapy, CD8+ cytotoxic T cells, CD4+ CD25+ FoxP3+ regulatory T cells, and myeloid-derived suppressor cells were labeled with superparamagnetic iron oxide particles. METHODS: Superparamagnetic iron oxide-labeled cells were injected into mice (one cell type/mouse) implanted with a human papillomavirus-based cervical cancer model...
November 29, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29191180/white-affluent-educated-parents-are-least-likely-to-choose-hpv-vaccination-for-their-children-a-cross-sectional-study-of-the-national-immunization-study-teen
#18
Echo L Warner, Qian Ding, Lisa M Pappas, Kevin Henry, Deanna Kepka
BACKGROUND: Human Papillomavirus (HPV) vaccination coverage is below national goals in the United States. Research is needed to inform strategically designed interventions that target sociodemographic groups with underutilization of HPV vaccination. METHODS: Secondary data analysis of the National Immunization Survey-Teen 2013 measured association of sociodemographic factors (e.g., ethnicity/race, insurance) with HPV vaccination among females and males ages 13-17 (N = 18,959)...
December 1, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29190725/modelling-the-effects-of-quadrivalent-human-papillomavirus-hpv-vaccination-in-puerto-rico
#19
Ana Patricia Ortiz, Karen J Ortiz-Ortiz, Moraima Ríos, José Laborde, Amit Kulkarni, Matthew Pillsbury, Andreas Lauschke, Homero A Monsanto, Cecile Marques-Goyco
BACKGROUND: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios. METHODS: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population...
2017: PloS One
https://www.readbyqxmd.com/read/29185272/prevalence-of-human-papillomavirus-genotypes-and-precancerous-cervical-lesions-in-a-screening-population-in-the-republic-of-korea-2014-2016
#20
Yung Taek Ouh, Kyung Jin Min, Hyun Woong Cho, Moran Ki, Jin Kyoung Oh, Sang Yop Shin, Jin Hwa Hong, Jae Kwan Lee
OBJECTIVE: Knowledge regarding the prevalence and distribution of human papillomavirus (HPV) genotyping in healthy women is important in establishing strategies for cervical cancer screening and HPV vaccination. METHODS: A total of 18,170 women who visited a Korean Medical Institute for health check-ups were recruited retrospectively; they underwent HPV genotyping and conventional cervical cytology. An HPV DNA test was performed using the Anyplex™ II HPV 28 detection system (Seegene) or HPV Liquid Bead Microarray (Osang Healthcare)...
January 2018: Journal of Gynecologic Oncology
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