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https://www.readbyqxmd.com/read/28224608/inter-and-intrarater-clinician-agreement-on-joint-motion-patterns-during-gait-in-children-with-cerebral-palsy
#1
Angela Nieuwenhuys, Eirini Papageorgiou, Guy Molenaers, Davide Monari, Tinne de Laet, Kaat Desloovere
AIM: This study aimed to quantify the inter- and intrarater clinician agreement on joint motion patterns in children with spastic cerebral palsy (CP), which were recently specified by a Delphi consensus study. It also examined whether experience with three-dimensional gait analysis (3DGA) is a prerequisite for using the patterns. METHOD: The experimental group consisted of 82 patients with CP (57 males, 25 females; uni-/bilateral CP [n=27/55]; Gross Motor Function Classification System levels I to III; mean age 9y 5mo [range 4y-18y])...
February 22, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28220607/neurological-and-spinal-manifestations-of-the-ehlers-danlos-syndromes
#2
Fraser C Henderson, Claudiu Austin, Edward Benzel, Paolo Bolognese, Richard Ellenbogen, Clair A Francomano, Candace Ireton, Petra Klinge, Myles Koby, Donlin Long, Sunil Patel, Eric L Singman, Nicol C Voermans
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin extensibility, and tissue fragility. This communication briefly reports upon the neurological manifestations that arise including the weakness of the ligaments of the craniocervical junction and spine, early disc degeneration, and the weakness of the epineurium and perineurium surrounding peripheral nerves. Entrapment, deformation, and biophysical deformative stresses exerted upon the nervous system may alter gene expression, neuronal function and phenotypic expression...
February 21, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28220268/anterolateral-ligament-expert-group-consensus-paper-on-the-management-of-internal-rotation-and-instability-of-the-anterior-cruciate-ligament-deficient-knee
#3
REVIEW
Bertrand Sonnery-Cottet, Matthew Daggett, Jean-Marie Fayard, Andrea Ferretti, Camilo Partezani Helito, Martin Lind, Edoardo Monaco, Vitor Barion Castro de Pádua, Mathieu Thaunat, Adrian Wilson, Stefano Zaffagnini, Jacco Zijl, Steven Claes
Purpose of this paper is to provide an overview of the latest research on the anterolateral ligament (ALL) and present the consensus of the ALL Expert Group on the anatomy, radiographic landmarks, biomechanics, clinical and radiographic diagnosis, lesion classification, surgical technique and clinical outcomes. A consensus on controversial subjects surrounding the ALL and anterolateral knee instability has been established based on the opinion of experts, the latest publications on the subject and an exchange of experiences during the ALL Experts Meeting (November 2015, Lyon, France)...
February 20, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28207979/a-comparison-of-injuries-in-elite-male-and-female-football-players-a-5-season-prospective-study
#4
Jon Larruskain, Jose A Lekue, Nerea Diaz, Adrian Odriozola, Susana M Gil
The aim was to compare the epidemiology of injuries between elite male and female football players from the same club. Injuries and individual exposure time in a male team and a female team, both playing in the Spanish first division, were prospectively recorded by the club's medical staff for five seasons (2010-2015) following the FIFA consensus statement. Total, training and match exposure hours per player-season were 20% higher for men compared to women (P < 0.01). Total, training and match injury incidence were 30-40% higher in men (P ≤ 0...
February 16, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28205026/common-strategic-research-agenda-for-radiation-protection-in-medicine
#5
(no author information available yet)
: Reflecting the change in funding strategies for European research projects, and the goal to jointly improve medical radiation protection through sustainable research efforts, five medical societies involved in the application of ionising radiation (European Association of Nuclear Medicine, EANM; European Federation of Organizations for Medical Physics. EFOMP; European Federation of Radiographer Societies, EFRS; European Society of Radiology, ESR; European Society for Radiotherapy and Oncology, ESTRO) have identified research areas of common interest and developed this first edition of the Common Strategic Research Agenda (SRA) for medical radiation protection...
February 15, 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/28201839/mr-imaging-in-patients-with-cardiac-pacemakers-and-implantable-cardioverter-defibrillators
#6
Torsten Sommer, Wolfgang Bauer, Katharina Fischbach, Christof Kolb, Roger Luechinger, Uwe Wiegand, Joachim Lotz, Ingo Eitel, Matthias Gutberlet, Holger Thiele, Hans H Schild, Malte Kelm, Harald H Quick, Jeanette Schulz-Menger, Jörg Barkhausen, Dietmar Bänsch
This joint consensus paper of the German Roentgen Society and the German Cardiac Society provides physical and electrophysiological background information and specific recommendations for the procedural management of patients with cardiac pacemakers (PM) and implantable cardioverter defibrillators (ICD) undergoing magnetic resonance (MR) imaging. The paper outlines the responsibilities of radiologists and cardiologists regarding patient education, indications, and monitoring with modification of MR sequences and PM/ICD reprogramming strategies being discussed in particular...
February 15, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28199015/european-society-of-endocrine-surgeons-eses-and-european-network-for-the-study-of-adrenal-tumours-ensat-recommendations-for-the-surgical-management-of-adrenocortical-carcinoma
#7
S Gaujoux, R Mihai
BACKGROUND: Radical surgery provides the best chance of cure for adrenocortical carcinoma (ACC), but perioperative surgical care for these patients is yet to be standardized. METHODS: A working group appointed jointly by ENSAT and ESES used Delphi methodology to produce evidence-based recommendations for the perioperative surgical care of patients with ACC. Papers were retrieved from electronic databases. Evidence and recommendations were classified according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system, and were discussed until consensus was reached within the group...
March 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28198156/prevalence-of-secondary-sj%C3%A3-gren-s-syndrome-in-indian-patients-with-rheumatoid-arthritis-a-single-center-study
#8
Krishna Santosh, Varun Dhir, Surjit Singh, Ashwani Sood, Amit Gupta, Aman Sharma, Shefali Sharma
AIM: To assess the prevalence of secondary Sjögren's syndrome (sSS) and its association with joint damage in patients with rheumatoid arthritis (RA) from northern India. METHODS: Patients included had RA, fulfilling the 1987 American College of Rheumatology criteria, with disease duration of more than 1 year. They were administered a sicca questionnaire that included six questions from subjective criteria of American European Consensus Group (AECG) criteria. Those who answered affirmatively to at least one question underwent Schirmer I test (ocular function) and salivary scintigraphy (salivary gland involvement)...
February 15, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28187789/collaboration-between-specialties-for-respiratory-allergies-in-the-international-classification-of-diseases-icd-11
#9
Luciana Kase Tanno, Moises Calderon, Jeffrey F Linzer, Robert J G Chalmers, Pascal Demoly
BACKGROUND: The International Classification of Diseases (ICD) has been grouping the allergic and hypersensitivity disorders involving the respiratory tract under topographic distribution, regardless of the underlying mechanisms, triggers or concepts currently in use for allergic and hypersensitivity conditions. In order to strengthen awareness and deliberate the creation of the new "Allergic or hypersensitivity disorders involving the respiratory tract" section of the ICD-11, we here propose make the building process public...
February 10, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28185005/management-and-follow-up-of-gallbladder-polyps-joint-guidelines-between-the-european-society-of-gastrointestinal-and-abdominal-radiology-esgar-european-association-for-endoscopic-surgery-and-other-interventional-techniques-eaes-international-society-of-digestive
#10
Rebecca Wiles, Ruedi F Thoeni, Sorin Traian Barbu, Yogesh K Vashist, Søren Rafael Rafaelsen, Catherine Dewhurst, Marianna Arvanitakis, Max Lahaye, Marek Soltes, Julie Perinel, Stuart Ashley Roberts
OBJECTIVES: The management of incidentally detected gallbladder polyps on radiological examinations is contentious. The incidental radiological finding of a gallbladder polyp can therefore be problematic for the radiologist and the clinician who referred the patient for the radiological examination. To address this a joint guideline was created by the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery - European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE)...
February 9, 2017: European Radiology
https://www.readbyqxmd.com/read/28182577/expressing-analytical-performance-from-multi-sample-evaluation-in-laboratory-eqa
#11
Marc H M Thelen, Rob T P Jansen, Cas W Weykamp, Herman Steigstra, Ron Meijer, Christa M Cobbaert
BACKGROUND: To provide its participants with an external quality assessment system (EQAS) that can be used to check trueness, the Dutch EQAS organizer, Organization for Quality Assessment of Laboratory Diagnostics (SKML), has innovated its general chemistry scheme over the last decade by introducing fresh frozen commutable samples whose values were assigned by Joint Committee for Traceability in Laboratory Medicine (JCTLM)-listed reference laboratories using reference methods where possible...
February 9, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28165873/overuse-physeal-injuries-in-youth-athletes
#12
Amanda Arnold, Charles A Thigpen, Paul F Beattie, Michael J Kissenberth, Ellen Shanley
CONTEXT: Despite rising awareness of the risks associated with sports participation, overuse injuries continue to increase in youth athlete populations. Physeal injuries are one type of overuse injury exclusive to pediatric populations that are often sustained during athletic practice or competition. Overuse physeal injuries are, in theory, preventable; however, little consensus has been reached surrounding the risk factors, prevention, and treatment strategies. OBJECTIVE: This systematic review summarizes the best available evidence concerning overuse physeal injuries in youth and adolescent athletes...
March 2017: Sports Health
https://www.readbyqxmd.com/read/28162839/a-systematic-review-of-measurement-properties-of-patient-reported-outcome-measures-used-in-patients-undergoing-total-knee-arthroplasty
#13
Joel J Gagnier, Megan Mullins, Hsiaomin Huang, Danica Marinac-Dabic, Anna Ghambaryan, Benjamin Eloff, Faisal Mirza, Manuel Bayona
BACKGROUND: While clinical research on total knee arthroplasty (TKA) outcomes is prevalent in the literature, studies often have poor methodological and reporting quality. A high-quality patient-reported outcome instrument is reliable, valid, and responsive. Many studies evaluate these properties, but none have done so with a systematic and accepted method. The objectives of this study were to identify patient-reported outcome measures (PROMs) for TKA, and to critically appraise, compare, and summarize their psychometric properties using accepted methods...
January 10, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28158933/interventions-for-treating-simple-bone-cysts-in-the-long-bones-of-children
#14
REVIEW
Jia-Guo Zhao, Jia Wang, Wan-Jie Huang, Peng Zhang, Ning Ding, Jian Shang
BACKGROUND: Simple bone cysts, also known as a unicameral bone cysts or solitary bone cysts, are the most common type of benign bone lesion in growing children. Cysts may lead to repeated pathological fracture (fracture that occurs in an area of bone weakened by a disease process). Occasionally, these fractures may result in symptomatic malunion. The main goals of treatment are to decrease the risk of pathological fracture, enhance cyst healing and resolve pain. Despite the numerous treatment methods that have been used for simple bone cysts in long bones of children, there is no consensus on the best procedure...
February 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28154552/chemokines-associated-with-pathologic-responses-to-orthopedic-implant-debris
#15
REVIEW
Nadim J Hallab, Joshua J Jacobs
Despite the success in returning people to health saving mobility and high quality of life, the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after approximately 15-25 years of use, due to slow progressive subtle inflammation to implant debris compromising the bone implant interface. This local inflammatory pseudo disease state is primarily caused by implant debris interaction with innate immune cells, i.e., macrophages. This implant debris can also activate an adaptive immune reaction giving rise to the concept of implant-related metal sensitivity...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28149325/meta-analytic-support-vector-machine-for-integrating-multiple-omics-data
#16
SungHwan Kim, Jae-Hwan Jhong, JungJun Lee, Ja-Yong Koo
BACKGROUND: Of late, high-throughput microarray and sequencing data have been extensively used to monitor biomarkers and biological processes related to many diseases. Under this circumstance, the support vector machine (SVM) has been popularly used and been successful for gene selection in many applications. Despite surpassing benefits of the SVMs, single data analysis using small- and mid-size of data inevitably runs into the problem of low reproducibility and statistical power. To address this problem, we propose a meta-analytic support vector machine (Meta-SVM) that can accommodate multiple omics data, making it possible to detect consensus genes associated with diseases across studies...
2017: BioData Mining
https://www.readbyqxmd.com/read/28147327/validation-of-different-staging-systems-for-hepatocellular-carcinoma-in-a-cohort-of-249-patients-undergoing-radiotherapy
#17
Zhi-Rui Zhou, Min Liu, Hui-Rong Lu, Ye-Fei Li, Shi-Xiong Liang, Chun-Yan Zhang
There is no consensus on predicting prognosis for hepatocellular carcinoma patients undergoing radiotherapy. This study aims to evaluate the validity of different staging systems. Overall, 249 hepatocellular carcinoma patients were evaluated retrospectively. All patients were classified by different staging systems. The cumulative survival rates were calculated using the Kaplan-Meier method, and survival curves were compared using the log-rank test. Harrell's concordance index (c-index) was calculated. The 1-, 3-, and 5-year overall survival rates were 58%, 31% and 20%, respectively...
January 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28146002/development-of-the-ibd-disk-a-visual-self-administered-tool-for-assessing-disability-in-inflammatory-bowel-diseases
#18
Subrata Ghosh, Edouard Louis, Laurent Beaugerie, Peter Bossuyt, Guillaume Bouguen, Arnaud Bourreille, Marc Ferrante, Denis Franchimont, Karen Frost, Xavier Hebuterne, John K Marshall, Ciara OʼShea, Greg Rosenfeld, Chadwick Williams, Laurent Peyrin-Biroulet
BACKGROUND: The Inflammatory bowel disease (IBD) Disability Index is a validated tool that evaluates functional status; however, it is used mainly in the clinical trial setting. We describe the use of an iterative Delphi consensus process to develop the IBD Disk-a shortened, self-administered adaption of the validated IBD Disability Index-to give immediate visual representation of patient-reported IBD-related disability. METHODS: In the preparatory phase, the IBD CONNECT group (30 health care professionals) ranked IBD Disability Index items in the perceived order of importance...
January 31, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28130632/developments-in-breeding-of-agaricus-bisporus-var-bisporus-progress-made-and-technical-and-legal-hurdles-to-take
#19
REVIEW
Anton S M Sonnenberg, Johan J P Baars, Wei Gao, Richard G F Visser
True breeding of button mushrooms has hardly been done in the last decades, despite this species being one of the most cultivated mushrooms worldwide. Research done in the last 20 years has identified and characterised new germplasm and improved our understanding of the genetic base for some traits. A substantial collection of wild-collected strains is now available and partly characterised for a number of important traits such as disease resistance and yield. Most of the variations found in a number of important agronomic traits have a considerable heritability and are thus useful for breeding...
January 28, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28127252/genetic-dissection-of-powdery-mildew-resistance-in-interspecific-half-sib-grapevine-families-using-snp-based-maps
#20
Soon Li Teh, Jonathan Fresnedo-Ramírez, Matthew D Clark, David M Gadoury, Qi Sun, Lance Cadle-Davidson, James J Luby
Quantitative trait locus (QTL) identification in perennial fruit crops is impeded largely by their lengthy generation time, resulting in costly and labor-intensive maintenance of breeding programs. In a grapevine (genus Vitis) breeding program, although experimental families are typically unreplicated, the genetic backgrounds may contain similar progenitors previously selected due to their contribution of favorable alleles. In this study, we investigated the utility of joint QTL identification provided by analyzing half-sib families...
2017: Molecular Breeding: New Strategies in Plant Improvement
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