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https://www.readbyqxmd.com/read/28739172/emergence-and-maintenance-of-menopause-in-humans-a-game-theory-model
#1
Valentin Thouzeau, Michel Raymond
Menopause, the permanent cessation of ovulation, occurs in women well before the end of their expected life span. Several adaptive hypotheses have been proposed to solve this evolutionary puzzle, each based on a possible fitness benefit derived from an early reproductive senescence, but no consensus has emerged. The construction of a game theory model allowed us to jointly study the main adaptive hypotheses in emergence and maintenance of menopause. Four classical hypotheses on the benefits of menopause were considered (decreased maternal mortality, increased grandmothering, decreased conflict over reproductive resources between older and younger females, and changes in their relatedness) plus a fifth one derived from a possible pleiotropic trade-off...
July 21, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28738834/the-value-of-99m-tc-methylene-diphosphonate-single-photon-emission-computed-tomography-computed-tomography-in-diagnosis-of-fibrous-dysplasia
#2
Linqi Zhang, Qiao He, Wei Li, Rusen Zhang
BACKGROUND: Fibrous dysplasia (FD) is a rare benign bone disorder in which the normal bone is replaced by immature fibro-osseous tissue. However, some case reports have reported that FD showed significantly increased (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) uptake on whole-body bone scintigraphy (WBS), which may mimic bone metastasis or skeletal involvement of the patients with known cancer. Thus, the purpose of present study is to observe the reliable characteristics and usefulness of single photon emission computed tomography/computed tomography (SPECT/CT) for the diagnosis of FD...
July 24, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28733672/trainee-surgeons-affect-operative-time-but-not-outcome-in-minimally-invasive-total-hip-arthroplasty
#3
Markus Weber, Achim Benditz, Michael Woerner, Daniela Weber, Joachim Grifka, Tobias Renkawitz
Training of young surgeons in total hip arthroplasty (THA) is crucial, but might affect operative time and outcome especially in minimally invasive (MIS) THA. We asked whether the learning curve of orthopaedic residents trained on MIS THA has an impact on (1) operative time (2) complication rates and (3) early postoperative outcome. In a retrospective analysis of over 1000 MIS THAs from our institutional joint registry, operative time, complication rates, patient reported outcome measures (Western Ontario and McMaster Universities Arthritis Index [WOMAC] and Euro-Qol 5D-5L [EQ-5D]) within the first year and responder rates for positive outcome as defined by the Outcome Measures in Rheumatology and Osteoarthritis Research Society International consensus responder (OMERACT-OARSI) criteria were compared between trainee and senior surgeons...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729542/reaching-agreement-in-quantum-hybrid-networks
#4
Guodong Shi, Bo Li, Zibo Miao, Peter M Dower, Matthew R James
We consider a basic quantum hybrid network model consisting of a number of nodes each holding a qubit, for which the aim is to drive the network to a consensus in the sense that all qubits reach a common state. Projective measurements are applied serving as control means, and the measurement results are exchanged among the nodes via classical communication channels. In this way the quantum-opeartion/classical-communication nature of hybrid quantum networks is captured, although coherent states and joint operations are not taken into consideration in order to facilitate a clear and explicit analysis...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728206/-subaxial-cervical-spine-injuries-treatment-recommendations-of-the-german-orthopedic-and-trauma-society
#5
Philipp Schleicher, Matti Scholz, Frank Kandziora, Andreas Badke, Florian Hans Brakopp, Helmut Klaus Friedrich Ekkerlein, Erol Gercek, Rene Hartensuer, Philipp Hartung, Jan-Sven Gilbert Jarvers, Philipp Kobbe, Stefan Matschke, Robert Morrison, Christian W Müller, Miguel Pishnamaz, Maximilian Reinhold, Klaus John Schnake, Gregor Schmeiser, Gregor Stein, Bernhard Ullrich, Thomas Weiß, Volker Zimmermann
In a consensus process during four sessions in 2016, the working group "lower cervical spine" of the German Society for Orthopedic and Trauma Surgery (DGOU), formulated "Therapeutic Recommendations for the Lower Cervical Spine", taking into consideration the current literature. Therapeutic goals are a permanently stable, painless cervical spine and the protection against secondary neurologic damage while retaining the greatest possible amount of motion and spinal profile. Due to its ease of use and its proven good reliability, the AOSpine classification for subaxial cervical injuries should be used...
July 20, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28720138/plantar-plate-pathology-is-associated-with-erosive-disease-in-the-painful-forefoot-of-patients-with-rheumatoid-arthritis
#6
Heidi J Siddle, Richard J Hodgson, Elizabeth M A Hensor, Andrew J Grainger, Anthony C Redmond, Richard J Wakefield, Philip S Helliwell
BACKGROUND: Disease-related foot pathology is recognised to have a significant impact on mobility and functional capacity in the majority of patients with rheumatoid arthritis (RA). The forefoot is widely affected and the metatarsophalangeal (MTP) joints are the most common site of symptoms. The plantar plates are the fibrocartilaginous distal attachments of the plantar fascia inserting into the five proximal phalanges. Together with the transverse metatarsal ligament they prevent splaying of the forefoot and subluxation of the MTP joints...
July 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28718993/role-of-fdg-pet-mri-fdg-pet-ct-and-dynamic-susceptibility-contrast-perfusion-mri-in-differentiating-radiation-necrosis-from-tumor-recurrence-in-glioblastomas
#7
Mojgan Hojjati, Chaitra Badve, Vasant Garg, Curtis Tatsuoka, Lisa Rogers, Andrew Sloan, Peter Faulhaber, Pablo R Ros, Leo J Wolansky
BACKGROUND AND PURPOSE: To compare the utility of quantitative PET/MRI, dynamic susceptibility contrast (DSC) perfusion MRI (pMRI), and PET/CT in differentiating radiation necrosis (RN) from tumor recurrence (TR) in patients with treated glioblastoma multiforme (GBM). METHODS: The study included 24 patients with GBM treated with surgery, radiotherapy, and temozolomide who presented with progression on imaging follow-up. All patients underwent PET/MRI and pMRI during a single examination...
July 18, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28718946/evidence-for-plical-support-of-the-patella
#8
Robert M Geraghty, Michelle Spear
There is a consensus that there is no overt anterior joint capsule in the knee. However, other anterior structures act in lieu of a joint capsule: the quadriceps tendon and patellar retinacular fibres. In the absence of a capsule, the synovium forms the suprapatellar pouch. Other synovial structures, the plicae, are more controversial. They are often described as embryonic remnants with no function, despite surrounding the patella. We aimed to identify plical anatomy and histology on cadaveric dissection and to examine their embryology using the human virtual embryo website...
July 18, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28718317/hand-surgeons-and-orthopedic-trauma-surgeons-call-coverage-of-acute-upper-extremity-injuries-where-should-the-line-be-drawn
#9
Matthew B Cantlon, Andrew J Miller, Asif M Ilyas
BACKGROUND: There is a lack of consensus as to which subspecialty service should cover acute upper extremity injuries in the emergency department (ED). The purpose of the present study is to understand how upper extremity injuries are currently triaged to specialists and to assess the current opinion among hand and orthopedic trauma specialists as to how these injuries should be best triaged based on injury location and severity. METHODS: The American Association for Hand Surgery (AAHS) membership and Orthopaedic Trauma Association (OTA) membership were surveyed using a 28-item online questionnaire...
January 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28706815/arthroscopic-subcapital-realignment-in-chronic-and-stable-slipped-capital-femoral-epiphysis
#10
Bruno Dutra Roos, Marcelo Camargo de Assis, Milton Valdomiro Roos, Antero Camisa Júnior, Ezequiel Moreno Ungaretti Lima
Stable slipped capital femoral epiphysis (SCFE) is the most common disease in the adolescent hip, with an estimated frequency of 10.8 in every 100,000 individuals. Recent studies of the biomechanics of femoroacetabular impingement indicate that small anatomical deformities of the hip arising from SCFE can potentially cause permanent acetabular chondral damage. There is no consensus about the best treatment option, especially for cases of moderate or severe chronic slippage (Southwick classification). Some authors recommend treatment with fixation in situ, in the belief that remodeling of the residual deformity of the femoral neck during growth allows proper function of the hip joint...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28694035/assessment-of-the-itmig-statement-on-the-who-histological-classification-and-of-the-8th-tnm-staging-of-thymic-epithelial-tumors-of-a-series-of-188-thymic-epithelial-tumors
#11
Alexandra Meurgey, Nicolas Girard, Claire Merveilleux du Vignaux, Jean-Michel Maury, François Tronc, Françoise Thivolet-Bejui, Lara Chalabreysse
BACKGROUND: Thymic epithelial tumors (TETs) are rare intrathoracic malignancies which are categorized histologically according to the World Health Organization (WHO) classification, recently updated in 2015 based on a consensus statement of ITMIG; at the same time, the standard Masaoka-Koga staging system is intended to be replaced by the 8th edition of the TNM staging classification by the American Joint Committee on Cancer (AJCC)/Union Internationale Contre le Cancer (UICC) consortium...
July 7, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28692774/developing-and-refining-new-candidate-criteria-for-sle-classification-an-international-collaboration
#12
Sara K Tedeschi, Sindhu R Johnson, Dimitrios Boumpas, David Daikh, Thomas Dörner, David Jayne, Diane Kamen, Kirsten Lerstrøm, Marta Mosca, Rosalind Ramsey-Goldman, Corine Sinnette, David Wofsy, Josef S Smolen, Raymond P Naden, Martin Aringer, Karen H Costenbader
OBJECTIVES: We aimed to define candidate criteria within multi-phase development of SLE classification criteria, jointly supported by EULAR and ACR. Prior steps included item generation and reduction by Delphi exercise, further narrowed to 21 items in a Nominal Group Technique exercise. Our objectives were to apply an evidence-based approach to the 21 candidate criteria, and to develop hierarchical organization of criteria within domains. METHODS: A literature review identified the sensitivity and specificity of the 21 candidate criteria...
July 10, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28690561/interparental-conflict-relative-to-suicidal-ideation-in-chinese-adolescents-the-roles-of-coping-strategies-and-meaning-in-life
#13
Rongwei Zhang, Dan Li, Fei Chen, Béatrice M Ewalds-Kvist, Shihong Liu
The aim of this study was to explore the paths between interparental conflict and Chinese adolescents' suicidal ideation. Altogether 931 adolescents (Mage = 17.84, SD = 0.77, females = 531) completed the Dyadic Consensus Scale, Self-Report Coping Scale, Meaning in Life Questionnaire, and Positive and Negative Suicide Ideation questionnaires. Mediation analyses were conducted, focusing on the relations between interparental conflict and suicidal ideation along with coping styles and a sense of meaning in life...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28690356/diagnostic-index-an-open-source-tool-to-classify-tmj-oa-condyles
#14
Beatriz Paniagua, Laura Pascal, Juan Prieto, Jean Baptiste Vimort, Liliane Gomes, Marilia Yatabe, Antonio Carlos Ruellas, Francois Budin, Steve Pieper, Martin Styner, Erika Benavides, Lucia Cevidanes
Osteoarthritis (OA) of temporomandibular joints (TMJ) occurs in about 40% of the patients who present TMJ disorders. Despite its prevalence, OA diagnosis and treatment remain controversial since there are no clear symptoms of the disease, especially in early stages. Quantitative tools based on 3D imaging of the TMJ condyle have the potential to help characterize TMJ OA changes. The goals of the tools proposed in this study are to ultimately develop robust imaging markers for diagnosis and assessment of treatment efficacy...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28668197/improving-healthcare-value-through-clinical-community-and-supply-chain-collaboration
#15
Lisa Ishii, Renee Demski, K H Ken Lee, Zishan Mustafa, Steve Frank, Jean Paul Wolisnky, David Cohen, Jay Khanna, Joshua Ammerman, Harpal S Khanuja, Anthony S Unger, Lois Gould, Patricia Ann Wachter, Lauren Stearns, Ronald Werthman, Peter Pronovost
BACKGROUND: We hypothesized that integrating supply chain with clinical communities would allow for clinician-led supply cost reduction and improved value in an academic health system. METHODS: Three clinical communities (spine, joint, blood management) and one clinical community-like physician led team of surgeon stakeholders partnered with the supply chain team on specific supply cost initiatives. The teams reviewed their specific utilization and cost data, and the physicians led consensus-building conversations over a series of team meetings to agree to standard supply utilization...
March 2017: Healthcare
https://www.readbyqxmd.com/read/28663391/equalisation-of-leg-lengths-in-total-hip-arthroplasty-for-patients-with-crowe-type-iv-developmental-dysplasia-of-the-hip-classification-and-management
#16
Y Li, X Zhang, Q Wang, X Peng, Q Wang, Y Jiang, Y Chen
AIMS: There is no consensus about the best method of achieving equal leg lengths at total hip arthroplasty (THA) in patients with Crowe type-IV developmental dysplasia of the hip (DDH). We reviewed our experience of a consecutive series of patients who underwent THA for this indication. PATIENTS AND METHODS: We retrospectively reviewed 78 patients (86 THAs) with Crowe type-IV DDH, including 64 women and 14 men, with a minimum follow-up of two years. The mean age at the time of surgery was 52...
July 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28662955/determining-the-threshold-for-hba1c-as-a-predictor-for-adverse-outcomes-after-total-joint-arthroplasty-a-multicenter-retrospective-study
#17
Majd Tarabichi, Noam Shohat, Michael M Kheir, Muyibat Adelani, David Brigati, Sean M Kearns, Pankajkumar Patel, John C Clohisy, Carlos A Higuera, Brett R Levine, Ran Schwarzkopf, Javad Parvizi, William A Jiranek
BACKGROUND: Although HbA1c is commonly used for assessing glycemic control before surgery, there is no consensus regarding its role and the appropriate threshold in predicting adverse outcomes. This study was designed to evaluate the potential link between HbA1c and subsequent periprosthetic joint infection (PJI), with the intention of determining the optimal threshold for HbA1c. METHODS: This is a multicenter retrospective study, which identified 1645 diabetic patients who underwent primary total joint arthroplasty (1004 knees and 641 hips) between 2001 and 2015...
May 11, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28657809/medical-oversight-educational-core-content-and-proposed-scopes-of-practice-of-wilderness-ems-providers-a-joint-project-developed-by-wilderness-ems-educators-medical-directors-and-regulators-using-a-delphi-approach
#18
Michael G Millin, David E Johnson, Tod Schimelpfenig, Keith Conover, Matthew Sholl, Jonnathan Busko, Rachael Alter, Will Smith, Jennifer Symonds, Peter Taillac, Seth C Hawkins
INTRODUCTION: A disparity exists between the skills needed to manage patients in wilderness EMS environments and the scopes of practice that are traditionally approved by state EMS regulators. In response, the National Association of EMS Physicians Wilderness EMS Committee led a project to define the educational core content supporting scopes of practice of wilderness EMS providers and the conditions when wilderness EMS providers should be required to have medical oversight. METHODS: Using a Delphi process, a group of experts in wilderness EMS, representing educators, medical directors, and regulators, developed model educational core content...
June 28, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28653866/the-role-of-athletic-trainers-in-preventing-and-managing-posttraumatic-osteoarthritis-in-physically-active-populations-a-consensus-statement-of-the-athletic-trainers-osteoarthritis-consortium
#19
Riann M Palmieri-Smith, Kenneth L Cameron, Lindsey J DiStefano, Jeffrey B Driban, Brian Pietrosimone, Abbey C Thomas, Timothy W Tourville, Athletic Trainers' Osteoarthritis Consortium
OBJECTIVE:   To provide athletic trainers with a fundamental understanding of the pathogenesis and risk factors associated with the development of posttraumatic osteoarthritis (PTOA) as well as the best current recommendations for preventing and managing this condition. BACKGROUND:   Posttraumatic osteoarthritis, or osteoarthritis that develops secondary to joint injury, accounts for approximately 5.5 million US cases annually. A young athlete with a joint injury is at high risk for PTOA before the age of 40, which could lead to the patient living more than half of his or her life with a painful and disabling disorder...
June 2, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28651596/varying-negative-work-assistance-at-the-ankle-with-a-soft-exosuit-during-loaded-walking
#20
Philippe Malcolm, Sangjun Lee, Simona Crea, Christopher Siviy, Fabricio Saucedo, Ignacio Galiana, Fausto A Panizzolo, Kenneth G Holt, Conor J Walsh
BACKGROUND: Only very recently, studies have shown that it is possible to reduce the metabolic rate of unloaded and loaded walking using robotic ankle exoskeletons. Some studies obtained this result by means of high positive work assistance while others combined negative and positive work assistance. There is no consensus about the isolated contribution of negative work assistance. Therefore, the aim of the present study is to examine the effect of varying negative work assistance at the ankle joint while maintaining a fixed level of positive work assistance with a multi-articular soft exosuit...
June 26, 2017: Journal of Neuroengineering and Rehabilitation
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