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https://www.readbyqxmd.com/read/29028863/the-future-of-non-invasive-rejuvenation-technology-devices
#1
Michael H Gold
<p>Non-invasive rejuvenation of the skin is performed regularly in many cosmetic offices. Using evidence-based medicine, we will review the various technologies being used for non-invasive rejuvenation. This includes the use of intense pulsed light (IPL), which has been thoroughly studied and shown to be quite useful for this type of rejuvenation in removing the red and brown pigments, as well as affecting collagen. Fractional lasers, both non-ablative and ablative in nature, also can show dramatic improvements in the skin and associated clinical studies are reviewed here...
June 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28432727/efficacy-of-fractionated-microneedle-radiofrequency-with-and-without-adding-subcision-for-the-treatment-of-atrophic-facial-acne-scars-a-randomized-split-face-clinical-study
#2
Gita Faghihi, Nazila Poostiyan, Ali Asilian, Bahareh Abtahi-Naeini, Masoom Shahbazi, Fariba Iraji, Farahnaz Fatemi Naeini, Mohammad Ali Nilforoushzadeh
BACKGROUND: There is no gold standard treatment for facial acne scars, and overall, little literature exists about the combination therapy for treatment of acne scar. AIMS: The aim of this study was to evaluate the efficacy of fractionated microneedle radiofrequency (FMR) vs FMR combined with subcision for the treatment of atrophic acne scars. PATIENTS/METHODS: This was a randomized, split-face clinical study of 25 patients with II-IV Fitzpatrick skin types with moderate to severe facial atrophic acne scars...
April 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28367261/long-term-nasal-and-peri-oral-tightening-by-a-single-fractional-noninsulated-microneedle-radiofrequency-treatment
#3
Yohei Tanaka
Background: The skin tightening effects induced by non-insulated microneedle radiofrequency have proved long-lasting. Our previous three-dimensional volumetric assessment showed significant facial tightening for up to six months. However, nasal and peri-oral tightening effects lasted longer. The objective of this study was to investigate the distribution of the long-term volumetric reduction in facial area induced by a single fractional non-insulated microneedle radiofrequency treatment. Methods: Fifteen Asian patients underwent full facial skin tightening using a sharply tapered non-insulated microneedle radiofrequency applicator with a novel fractionated pulse mode...
February 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28199493/aesthetic-and-functional-improvement-of-chronic-radiation-dermatitis-with-noninsulated-microneedle-fractional-radiofrequency
#4
Derek Ho, Ekaterina Kraeva, Joshua M Schulman, Jared Jagdeo
No abstract text is available yet for this article.
May 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28146245/comparison-of-physical-pretreatment-regimens-to-enhance-protoporphyrin-ix-uptake-in-photodynamic-therapy-a-randomized-clinical-trial
#5
RANDOMIZED CONTROLLED TRIAL
Christiane Bay, Catharina Margrethe Lerche, Bradford Ferrick, Peter Alshede Philipsen, Katrine Togsverd-Bo, Merete Haedersdal
Importance: Skin pretreatment is recommended for adequate penetration of topical photosensitizing agents and subsequent protoporphyrin IX (PPIX) accumulation in photodynamic therapy (PDT). Objective: To compare the relative potential of different physical pretreatments to enhance PPIX fluorescence in normal skin. Design, Setting, and Participants: This intraindividual, randomized clinical trial was performed from November 28 to December 20, 2014, at Bispebjerg Hospital, Copenhagen, Denmark, among 12 healthy volunteers 18 years or older...
April 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28095556/combination-therapy-for-acne-scarring-personal-experience-and-clinical-suggestions
#6
Lucija Kroepfl, Jason J Emer
Acne is one of the most prevalent skin conditions seen by dermatologists. The cosmetic sequelae of severe acne, including scarring and pigmentation, have a profound psychological impact on those in icted. Topical (eg, retinoids, antibiotics, dapsone, hydroxyacids) and oral treatments (eg, antibiotics and/or spironolactone) are often bene cial to control acne or in the instance of oral isotretinoin use, rid the acne permanently; however, these treatments have very little affect on the ultimate cosmetic outcome of the acne scarring and skin texture that results...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28095540/multi-center-pilot-study-to-evaluate-the-safety-pro-le-of-high-energy-fractionated-radiofrequency-with-insulated-microneedles-to-multiple-levels-of-the-dermis
#7
MULTICENTER STUDY
Joel L Cohen, Steven F Weiner, Jason N Pozner, Omar A Ibrahimi, David B Vasily, E Victor Ross, Zena Gabriel
In this multi-center pilot study, the safety pro le of high intensity focused radiofrequency (RF) delivered to the dermis was evaluated for safety in the treatment of the aging neck and face. A newly designed insulated microneedle system delivers a signi cant coagulative thermal injury into the dermis while sparing the epidermis from RF injury. Thirty- ve healthy subjects from seven aesthetic practices were evaluated, and data from each were incorporated in this case report. The subjects received a single treatment using settings that delivered the highest RF energies suggested from the new recommended protocols...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28009690/fractional-erbium-doped-yttrium-aluminum-garnet-laser-versus-microneedling-in-treatment-of-atrophic-acne-scars-a-randomized-split-face-clinical-study
#8
RANDOMIZED CONTROLLED TRIAL
Mai Abdel Raouf Osman, Hisham Ali Shokeir, Marwa M Fawzy
BACKGROUND: Ablative fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser and microneedling have been popularized in recent years and their effectiveness and side effects individually reported. No previous study, however, has directly compared the efficacy and safety between the 2 different treatments. OBJECTIVE: To compare the efficacy and safety of the ablative fractional Er:YAG laser and microneedling for the treatment of atrophic acne scars. MATERIALS AND METHODS: Thirty patients with atrophic acne scars were randomly treated in a split-face manner with a fractional Er:YAG laser on one side and microneedling on the other side...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27849406/curative-effects-of-microneedle-fractional-radiofrequency-system-on-skin-laxity-in-asian-patients-a-prospective-double-blind-randomized-controlled-face-split-study
#9
RANDOMIZED CONTROLLED TRIAL
Wenli Lu, Pinru Wu, Zhen Zhang, Jinan Chen, Xiangdong Chen, Biskup Ewelina
BACKGROUND: To date, no studies compared curative effects of thermal lesions in deep and superficial dermal layers in the same patient (face-split study). OBJECTIVE: To evaluate skin laxity effects of microneedle fractional radiofrequency induced thermal lesions in different dermal layers. METHODS AND MATERIALS: 13 patients underwent three sessions of a randomized face-split microneedle fractional radiofrequency system (MFRS) treatment of deep dermal and superficial dermal layer...
April 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27833475/noninvasive-transdermal-vaccination-using-hyaluronan-nanocarriers-and-laser-adjuvant
#10
Ki Su Kim, Hyemin Kim, Yunji Park, Won Ho Kong, Seung Woo Lee, Sheldon J J Kwok, Sei Kwang Hahn, Seok Hyun Yun
Vaccines are commonly administered by injection using needles. Although transdermal microneedles are less-invasive promising alternatives, needle-free topical vaccination without involving physical damage to the natural skin barrier is still sought after as it can further reduce needle-induced anxiety and simply administration. However, this long-standing goal has been elusive since the intact skin is impermeable to most macromolecules. Here, we show an efficient, non-invasive transdermal vaccination in mice by employing two key innovations: first, the use of hyaluronan (HA) as vaccine carriers and, second, non-ablative laser adjuvants...
April 19, 2016: Advanced Functional Materials
https://www.readbyqxmd.com/read/27608206/clinical-and-histologic-effects-of-fractional-microneedling-radiofrequency-treatment-on-rosacea
#11
RANDOMIZED CONTROLLED TRIAL
Seon Yong Park, Hyuck Hoon Kwon, Ji Young Yoon, Seonguk Min, Dae Hun Suh
BACKGROUND: Fractional microneedling radiofrequency (FMR) is an emerging treatment modality, but its effect on rosacea has not been studied yet. OBJECTIVE: To investigate the potential impact of FMR treatment on clinical improvement and histologic changes in rosacea patients. MATERIALS AND METHODS: A 12-week, prospective, randomized, split-face clinical trial was conducted. Two sessions of FMR were performed on one side of the cheeks with 4-week interval and the other side remained untreated...
December 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27594273/combination-of-microneedle-radiofrequency-rf-fractional-rf-skin-resurfacing-and-multi-source-non-ablative-skin-tightening-for-minimal-downtime-full-face-skin-rejuvenation
#12
Haim Kaplan, Lilach Kaplan
BACKGROUND: In the recent years, there is a growth in demand for radiofrequency (RF)-based procedures to improve skin texture, laxity and contour. The new generation of systems allow non-invasive and fractional resurfacing treatments on one platform. OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of a new treatment protocol using a multisource RF, combining 3 different modalities in each patient: [1] non-ablative RF skin tightening, [2] fractional skin resurfacing, and [3] microneedling RF for non-ablative coagulation and collagen remodelling...
December 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27496634/repeated-fractional-intradermal-dosing-of-an-inactivated-polio-vaccine-by-a-single-hollow-microneedle-leads-to-superior-immune-responses
#13
Pim Schipper, Koen van der Maaden, Stefan Romeijn, Cees Oomens, Gideon Kersten, Wim Jiskoot, Joke Bouwstra
The purpose of this study was to investigate the effect of various repeated fractional intradermal dosing schedules of inactivated polio vaccine serotype 1 (IPV1) on IPV1-specific IgG responses in rats. By utilizing an applicator that allowed for precisely controlled intradermal microinjections by using a single hollow microneedle, rats were immunized intradermally with 5 D-antigen units (DU) of IPV1 at 150μm skin depth. This dose was administered as a bolus, or in a repeated fractional dosing schedule: 4 doses of 1...
November 28, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27490716/non-insulated-smooth-motion-micro-needles-rf-fractional-treatment-for-wrinkle-reduction-and-lifting-of-the-lower-face-international-study
#14
Michael Gold, Mark Taylor, Kenneth Rothaus, Yohei Tanaka
INTRODUCTION: Skin aging occurs through both intrinsic and extrinsic processes. Fractional radiofrequency (RF) with a microneedling array is the newest form of fractional therapy to be useful in treating aging skin. The current study utilized a noninsulated fractional RF microneedling system. METHODS: This multicenter clinical trial saw 49 patients complete 3 monthly treatments with the new fractional RF microneedling treatments and be followed for 3 months following their last treatment...
October 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27363771/minimally-invasive-radiofrequency-devices
#15
REVIEW
Neil Sadick, Kenneth O Rothaus
This article reviews minimally invasive radiofrequency options for skin tightening, focusing on describing their mechanism of action and clinical profile in terms of safety and efficacy and presenting peer-reviewed articles associated with the specific technologies. Treatments offered by minimally invasive radiofrequency devices (fractional, microneedling, temperature-controlled) are increasing in popularity due to the dramatic effects they can have without requiring skin excision, downtime, or even extreme financial burden from the patient's perspective...
July 2016: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/27248025/ways-of-noninvasive-facial-skin-tightening-and-fat-reduction
#16
Klaus Fritz, Carmen Salavastru
For skin tightening, ablative and nonablative lasers have been used with various parameters full or fractionated. Currently, other energy-based technologies have been developed such as radiofrequency (RF) from mono- to multipolar, microneedling RF, and high-intensity focused ultrasound. They heat up the tissue to a clinical endpoint. Temperatures above 42°C stimulate fibroblasts to produce more collagen and some technologies produce small coagulation points that allow to shrink and to tighten the tissue with less downtime or side effects...
June 2016: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/27247943/thermal-response-of-in-vivo-human-skin-to-fractional-radiofrequency-microneedle-device
#17
Woraphong Manuskiatti, Penvadee Pattanaprichakul, Siriluk Inthasotti, Panitta Sitthinamsuwan, Suchanan Hanamornroongruang, Rungsima Wanitphakdeedecha, Sorawuth Chu-Ongsakol
Background. Fractional radiofrequency microneedle system (FRMS) is a novel fractional skin resurfacing system. Data on thermal response to this fractional resurfacing technique is limited. Objectives. To investigate histologic response of in vivo human skin to varying energy settings and pulse stacking of a FRMS in dark-skinned subjects. Methods. Two female volunteers who were scheduled for abdominoplasty received treatment with a FRMS with varying energy settings at 6 time periods including 3 months, 1 month, 1 week, 3 days, 1 day, and the time immediately before abdominoplasty...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27224897/melasma-and-post-inflammatory-hyperpigmentation-management-update-and-expert-opinion
#18
REVIEW
B Sofen, G Prado, J Emer
Dyschromia is a leading cause for cosmetic consultation, especially in those with diverse skin types (mixture of ethnicities) and with the rise of non-core and untrained physicians performing cosmetic procedures. Melasma and post-inflammatory hyperpigmentation (PIH) account for the majority of cases and are characterized by pigmented macules and patches distributed symmetrically in sun-exposed areas of the forehead, cheeks, and chin in melasma, and irregularly in areas of inflammation or an inciting traumatic event with PIH...
January 2016: Skin Therapy Letter
https://www.readbyqxmd.com/read/27128248/rejuvenation-of-the-upper-face-and-periocular-region-combining-neuromodulator-facial-filler-laser-light-and-energy-based-therapies-for-optimal-results
#19
REVIEW
Nicole Langelier, Katie Beleznay, Julie Woodward
BACKGROUND: The upper face and periocular region is a complex and dynamic part of the face. Successful rejuvenation requires a combination of minimally invasive modalities to fill dents and hollows, resurface rhytides, improve pigmentation, and smooth the mimetic muscles of the face without masking facial expression. METHODS: Using review of the literature and clinical experience, the authors discuss our strategy for combining botulinum toxin, facial filler, ablative laser, intense pulsed light, microfocused ultrasound, and microneedle fractional radiofrequency to treat aesthetic problems of the upper face including brow ptosis, temple volume loss, A-frame deformity of the superior sulcus, and superficial and deep rhytides...
May 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27128241/a-combination-approach-to-surgical-scars
#20
REVIEW
Robert E Eilers, Edward Victor Ross, Joel L Cohen, Arisa E Ortiz
BACKGROUND: Scar formation from surgical procedures is an unavoidable risk. Despite measures taken by both the surgeon and patient during the perioperative and postoperative periods to maximize cosmesis, some patients will wish to pursue surgical or laser scar revision. OBJECTIVE: The authors propose a treatment algorithm to assist in approaching surgical scar revision with combination treatments. MATERIALS AND METHODS: A PubMed search was performed on various surgical scar revision techniques...
May 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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