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https://www.readbyqxmd.com/read/28169912/radial-probe-ultrasound-guided-cryobiopsy
#1
Ilya G Berim, Ali I Saeed, Ahmed Awab, Adam Highley, Agnes Colanta, Fawad Chaudry
Fluoroscopy-guided transbronchial forceps biopsy has a low diagnostic yield in patients with radiographic suspicion of interstitial lung disease. Cryobiopsy has a higher diagnostic yield likely due to preserved lung architecture and larger biopsies; however, there is an increased risk of major airway bleeding and pneumothorax. Simultaneous use of endobronchial balloon blocker allows for containment of bleeding after cryobiopsy to the affected lobe. In the current article we describe use of radial ultrasound in identification of a target lung parenchyma without a major blood vessel adjacent to distal bronchi...
February 6, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28114787/multi-point-thermal-sensors-associated-with-improved-oncological-outcomes-following-cryoablation
#2
Jeremy W Martin, Roshan Patel, Zhamshid Okhunov, Aashay Vyas, Duane Vajgrt, Ralph Clayman
INTRODUCTION: Cryoablation (CA) is a minimally invasive modality for the management of small renal cortical neoplasms (RCN). Successful ablation is dependent on achieving target temperatures during CA that result in tumor cell death. We investigated long-term oncological outcomes following CA using Multi-Point Thermal Sensors (MTS), which allow precise temperature determination at four points along the needle. METHODS: We performed a retrospective review of 20 patients with < 4 cm RCN who underwent de novo CA from 2005 to 2009...
January 23, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28076822/an-in-vitro-analysis-of-the-size-and-shape-of-cryolesions-for-facet-joint-denervation
#3
T Wolter, Y Bozhkov, S M Knoeller
OBJECTIVES: Lumbar facet joint syndrome (LFJS) is the cause of lower back pain in 15-54% of the patients. Clinical studies of cryotherapy for LFJS have reported promising outcomes. However, few studies have focused on the technical aspects of cryoneurolysis for LFJS. The aim of the study was to determine the size and shape of cryolesions in vitro and to determine how they are affected by the duration of freezing, size of the cryoprobe and distance and angulation to an osseous boundary layer...
February 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28072428/3d-modelling-on-biodegradable-nanoparticle-enhanced-cryoablation-of-liver-tumor-based-on-real-anatomical-model
#4
S Y Xu, Z Z He, Y X Zhou, J Liu
BACKGROUND: Nanoparticle-enhanced freezing is of great importance for developing a conformal targeted cryoablation for liver tumor with complex shape. However, the safety and biocompatibility of nanoparticles should also be of major concerns. OBJECTIVE: This study is to investigate the enhanced cryoablation mediated by the MgO nanoparticles which are nontoxic, biodegradable, and have few side-effects on the human body. MATERIALS AND METHODS: A three-dimensional numerical model has been developed based on a real geometrical anatomical structure to characterize such nanocryosurgical freezing of liver tumor...
November 2016: Cryo Letters
https://www.readbyqxmd.com/read/28002868/ultrasound-guided-cryoanalgesia-of-peripheral-nerve-lesions
#5
Sahlya Djebbar, Ignacio M Rossi, Ronald S Adler
The real-time nature of ultrasound makes it ideally suited to provide guidance for a variety of musculoskeletal interventional procedures involving peripheral nerves. Continuous observation of the needle ensures proper placement and allows continuous monitoring when performing localized ablative therapy and therefore more accurate positioning of a cryoprobe, use of smaller needles, as well as access to small structures. We describe our experience performing cryoablative procedures. Patients undergoing cryoneurolysis have largely reported varying degrees of long-term pain relief and improvement in function; no serious complications have yet been identified...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/27977039/thermal-conductivity-of-human-bone-in-cryoprobe-freezing-as-related-to-density
#6
Kyle E Walker, Todd Baldini, Bennie G Lindeque
Cryoprobes create localized cell destruction through freezing. Bone is resistant to temperature flow but is susceptible to freezing necrosis at warmer temperatures than tumor cells. Few studies have determined the thermal conductivity of human bone. No studies have examined conductivity as related to density. The study goal was to examine thermal conductivity in human bone while comparing differences between cancellous and cortical bone. An additional goal was to establish a relationship between bone density and thermal conductivity...
December 9, 2016: Orthopedics
https://www.readbyqxmd.com/read/27886022/fracture-risk-of-vertebral-bodies-after-cryosurgery-using-a-miniature-cryoprobe-a-biomechanical-in-vitro-analysis-on-human-bones
#7
K Zarghooni, L Westermann, R Sobottke, M Röllinghoff, J Bredow, J Siewe, Peer Eysel, M J Scheyerer
INTRODUCTION: Due to spinal instability and compressive neurologic deficits surgical management is sometimes necessary in patients with metastatic spinal lesions. However, in some cases open surgery is not possible and minimally invasive procedures, like cryoablation, are needed. The aim of the current study was to investigate whether a miniature cryoprobe provides adequate tissue cooling in vertebrae and to evaluate the direct impact of cryosurgery on vertebral body stability. MATERIALS AND METHODS: Twelve thoracic vertebral bodies were harvested from fresh cadavers...
November 18, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27833528/gray-and-white-matter-demyelination-and-remyelination-detected-with-multimodal-quantitative-mri-analysis-at-11-7t-in-a-chronic-mouse-model-of-multiple-sclerosis
#8
Alexandra Petiet, Marie-Stéphane Aigrot, Bruno Stankoff
Myelin is a component of the nervous system that is disrupted in multiple sclerosis, resulting in neuro-axonal degeneration. The longitudinal effect of chronic cuprizone-induced demyelination was investigated in the cerebral gray and white matter of treated mice and the spontaneous remyelination upon treatment interruption. Multimodal Magnetic Resonance Imaging and a Cryoprobe were used at 11.7T to measure signal intensity ratios, T2 values and diffusion metrics. The results showed significant and reversible modifications in white matter and gray matter regions such as in the rostral and caudal corpus callosum, the external capsule, the cerebellar peduncles, the caudate putamen, the thalamus, and the somatosensory cortex of treated mice...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27832044/early-results-of-the-modified-right-atrial-lesion-set-for-the-cox-cryomaze-procedure
#9
Faisal Habib Cheema, Muhammad Amir Younus, Osama T Siddiqui, Muhammad Jabran Younus, Muhammad Arif Mahmood, Mohammad Bin Pervez, Harold G Roberts
OBJECTIVE: The standard right atrial lesion (RAL) set, as originally outlined in the Cox-Maze III procedure, can be technically challenging when using a cryoprobe to create the lesions. We report our initial experience with an alternative set of RALs for the surgical treatment of atrial fibrillation (AF). METHODS: Between September 2011 and January 2015, a total of 112 patients underwent a CryoMaze procedure with biatrial lesions using argon-based cryoablation (cryoprobe temperature, -160°C)...
September 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27831814/pneumomediastinum-and-extensive-subcutaneous-emphysema-after-cryoprobe-transbronchial-lung-biopsy
#10
Karan Madan, Swapnil Mehta, Nishkarsh Gupta, Vijay Hadda, Anant Mohan, Randeep Guleria
No abstract text is available yet for this article.
November 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27758996/crohn-s-disease-associated-interstitial-lung-disease-mimicking-sarcoidosis-a-case-report-and-review-of-the-literature
#11
Choua Thao, Amir Lagstein, Tadashi Allen, Huseyin Erhan Dincer, Hyun Joo Kim
Respiratory involvement in Crohn's disease (CD) is a rare manifestation known to involve the large and small airways, lung parenchyma, and pleura. The clinical presentation is nonspecific, and diagnostic tests can mimic other pulmonary diseases, posing a diagnostic challenge and delay in treatment. We report a case of a 60-year-old female with a history of CD and psoriatic arthritis who presented with dyspnea, fever, and cough with abnormal radiological findings. Diagnostic testing revealed an elevated CD4:CD8 ratio in the bronchoalveolar lavage fluid, and cryoprobe lung biopsy results showed non-necrotizing granulomatous inflammation...
October 7, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/27702586/physiological-effects-of-a-habituation-procedure-for-functional-mri-in-awake-mice-using-a-cryogenic-radiofrequency-probe
#12
Keitaro Yoshida, Yu Mimura, Ryosuke Ishihara, Hiroshi Nishida, Yuji Komaki, Tomohito Minakuchi, Tomokazu Tsurugizawa, Masaru Mimura, Hideyuki Okano, Kenji F Tanaka, Norio Takata
BACKGROUND: Functional magnetic resonance imaging (fMRI) in mice is typically performed under anesthesia due to difficulties in holding the head of awake mice stably with a conventional three-point fixation method that uses a tooth-bar and earplugs. Although some studies have succeeded in fMRI in awake mice by attaching a head-post on the skull, this cannot be applied to fMRI using a high signal-to-noise ratio (SNR) cryogenic MRI-detector, CryoProbe, because it covers the head of a mouse closely...
December 1, 2016: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27625452/use-of-cryoprobe-for-removal-of-a-large-tracheobronchial-foreign-body-during-flexible-bronchoscopy
#13
Inderpaul Singh Sehgal, Sahajal Dhooria, Digambar Behera, Ritesh Agarwal
Foreign body (FB) inhalation in the tracheobronchial tree is an infrequently encountered event in adults. The diagnosis is suspected in the presence of a clinical history of aspiration and the presence of respiratory symptoms. Management involves confirmation by flexible bronchoscopy, which may be both diagnostic as well as therapeutic. However, in certain situations including those with large FB, FB embedded in granulation tissue or FB with very smooth margins, rigid bronchoscopy may be superior to flexible bronchoscopy in the retrieval of the FB...
September 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27583035/factors-affecting-lethal-isotherms-during-cryoablation-procedures
#14
Andrew C Rau, Ryan Siskey, Jorge A Ochoa, Tracy Good
BACKGROUND: Creating appropriately-sized, lethal isotherms during cryoablation of renal tumors is critical in order to achieve sufficiently-sized zones of cell death. To ensure adequate cell death in target treatment locations, surgeons must carefully select the type, size, location, and number of probes to be used, as well as various probe operating parameters. OBJECTIVE: The current study investigates the effects of probe type, operating pressure, and clinical method on the resulting sizes of isotherms in an in vitro gelatin model...
2016: Open Biomedical Engineering Journal
https://www.readbyqxmd.com/read/27567997/percutaneous-ct-guided-cryoablation-of-the-salivary-glands-in-a-porcine-model
#15
Ji Y Buethe, Salim Abboud, Kristie Brock, Greg Nizialek, Rod Rezaee, Jay Wasman, Jonathan Frankel, Dean A Nakamoto
PURPOSE: To evaluate the imaging, histologic changes and safety of computed tomography (CT)-guided cryoablation of the parotid glands in a porcine model. MATERIALS AND METHODS: Unilateral CT-guided parotid gland cryoablation was performed in 5 juvenile miniature pigs. The ablated parotid glands underwent 2 cycles of 10-minute freeze and 5-minute thaw using three 17-g cryoprobes. The animals were monitored daily for complications including pain, frostbite, infection, and sialocele or fistula formation...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27441784/transbronchial-lung-cryobiopsy-for-interstitial-lung-disease-diagnosis-a-perspective-from-members-of-the-pulmonary-pathology-society
#16
Kirtee Raparia, Dara L Aisner, Timothy Craig Allen, Mary Beth Beasley, Alain Borczuk, Philip T Cagle, Vera Capelozzi, Sanja Dacic, Lida P Hariri, Keith M Kerr, Sylvie Lantuejoul, Mari Mino-Kenudson, Natasha Rekhtman, Anja C Roden, Sinchita Roy-Chowdhuri, Lynette Sholl, Maxwell L Smith, Eric Thunnissen, Ming Sound Tsao, Yasushi Yatabe
Transbronchial lung cryobiopsy involves using a cryoprobe rather than forceps to obtain a bronchoscopic biopsy. Recent studies have shown that transbronchial cryobiopsy provides a larger specimen than conventional transbronchial forceps biopsy, and that the interobserver agreement in the interpretation of cryobiopsy specimens is comparable to that of a surgical lung biopsy. This is encouraging, and transbronchial lung cryobiopsy clearly has a role in the workup and diagnosis of interstitial lung diseases. However, very few patients who have been studied underwent both transbronchial lung cryobiopsy and surgical lung biopsy, and the available data suggest that the diagnostic accuracy of cryobiopsy may not be similar to that of surgical lung biopsy...
July 21, 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27387441/intra-patient-comparison-of-parietal-pleural-biopsies-by-rigid-forceps-flexible-forceps-and-cryoprobe-obtained-during-medical-thoracoscopy-a-prospective-series-of-80-cases-with-pleural-effusion
#17
H Wurps, N Schönfeld, T T Bauer, M Bock, C Duve, R Sauer, T Mairinger, S Griff
BACKGROUND: There is only few data available on the use of cryotechnique during medical thoracoscopy. METHODS: Medical thoracoscopy was performed in consecutive patients with pleural effusion. Prospectively, biopsies were taken by rigid forceps, flexible forceps and cryoprobe. Specimen size, depth and diagnostic yield were compared. RESULTS: 80 Patients were included. 408 biopsies were taken (205 rigid biopsies, 104 flexible biopsies, 99 cryobiopsies)...
July 7, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27385989/fibrobronchoscopic-cryosurgery-for-secondary-malignant-tumors-of-the-trachea-and-main-bronchi
#18
Qianli Ma, Bin Shi, Yanchu Tian, Deruo Liu
BACKGROUND: Patients with secondary malignant tracheal and main bronchial tumors may suffer severe symptoms as a result of major airway obstruction. Curative surgical resection is usually not suitable because of the presence of metastatic disease and poor performance status. In this study, the use of bronchoscopic cryosurgery to reopen the airway is analyzed. METHODS: The clinical records of 37 patients who experienced secondary maglinancies from December 2001 to January 2013 were retrospectively reviewed...
July 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/27378166/foreign-body-removal-is-getting-cooler
#19
EDITORIAL
Mikhail Kazachkov, Alfin Vicencio
Foreign body removal is commonly performed with the rigid bronchoscope. However, based on recent literature, extraction with the flexible bronchoscope has increased in popularity. Here, we discuss a new tool - the flexible cryoprobe - that may enhance foreign body retrieval in select patients and comment on the methods of foreign body extraction in the view of common clinical practice. Pediatr Pulmonol. 2016; 51:886-888. © 2016 Wiley Periodicals, Inc.
September 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27355358/evaluation-of-transbronchial-lung-cryobiopsy-size-and-freezing-time-a-prognostic-animal-study
#20
Matthew Ing, Rema A Oliver, Brian G G Oliver, William R Walsh, Jonathan P Williamson
BACKGROUND: Transbronchial lung biopsy using a cryoprobe is a novel way of sampling lung parenchyma. Correlation of freezing time with biopsy size and complications has not been evaluated in vivo. OBJECTIVES: The primary aim of the study is to evaluate the correlation between transbronchial cryobiopsy freezing time and size. The secondary aims are to evaluate histological quality of the biopsy and evaluate procedure-associated complications. METHODS: Transbronchial lung cryobiopsies were obtained from two anaesthetised sheep using a 1...
2016: Respiration; International Review of Thoracic Diseases
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