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https://www.readbyqxmd.com/read/27918636/4d-printing-of-shape-memory-based-personalized-endoluminal-medical-devices
#1
Matt Zarek, Nicola Mansour, Shir Shapira, Daniel Cohn
The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent...
December 5, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27882709/technical-note-using-a-tracheal-stent-for-conservative-management-of-speaking-valve-associated-tracheo-oesophageal-fistula
#2
M Cunnane, S Patil, R Sothinathan, D Walker, M Gaulton, L Pitkin
Surgical voice rehabilitation is an essential dimension of treatment following total laryngectomy. The gold standard is tracheo-oesophageal puncture and speaking valve placement. Whilst offering excellent phonation in many patients, there is a well-documented risk of valve associated fistula formation, the incidence of which varies from 1 to 21% (1) . Risk factors for delayed valve associated tracheo-oesophageal fistula include post chemo-radiotherapy (salvage laryngectomy), oesophageal stricture, persistent fungal infection and poor patient compliance in managing their speaking valve(2) ...
November 24, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27873529/tracheal-allotransplantation-and-regeneration
#3
P Delaere, M Molitor
Non-malignant and malignant obstruction of the tracheal airway causes significant morbidity and mortality. With increased use of artificial airways, benign and iatrogenic complications are increasing. A tracheal stenosis that is less than 5 cm in length can be resected with end-to-end anastomosis. Longer tracheal lesions can be treated in a palliative way by placement of a stent to secure airway lumen patency. The management of tracheal defects is an evolving field. Tracheal transplantation and tracheal regeneration may provide major treatment advances to cases with long-segment tracheal involvement...
2016: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/27873304/stent-induced-tracheal-stenosis-can-be-predicted-by-il-8-expression-in-rabbits
#4
Elena Arellano-Orden, Carolina Serrano, Ana Montes-Worboys, Verónica Sánchez-López, Alicia Laborda, Fernando Lostalé, Celia Lahuerta, Francisco Rodríguez-Panadero, Miguel Ángel de Gregorio
BACKGROUND: Bare metal stents may cause complications like fibrous encapsulation, granulation and tracheal stenosis. We investigated the behavior of three commercially available stents in vivo (rabbits) and in vitro (co-culture of those stents with epithelial and fibroblast cell lines). Also, we investigated whether development of tracheal stenosis could be predicted by any biological marker. METHODS: The tracheae of 30 rabbits were implanted with either nitinol stents, with or without paclitaxel elution, or a cobalt-based stent...
November 22, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27863648/biodegradable-airway-stents-in-infants-potential-life-threatening-pitfalls
#5
B Sztanó, G Kiss, K Márai, G Rácz, I Szegesdi, K Rácz, G Katona, L Rovó
OBJECTIVE: The solution of severe tracheobronchial obstructions in early childhood means a great challenge. Biodegradable stents were intended to be a minimally invasive temporary solution which may decrease the number of interventions and limit the possible complications of stenting procedures. However, our first experiences have brought out a new, - especially in childhood - potentially life-threatening complication of this concept. METHODS: Five SX-ELLA biodegradable polydioxanone stents was applied in three patients because of severe tracheobronchial obstruction: congenital tracheomalacia (7 day-old), acquired tracheomalacia (10 month-old), and congenital trachea-bronchomalacia (10 month-old)...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27847813/jet-ventilation-during-rigid-bronchoscopy-in-adults-a-focused-review
#6
REVIEW
Laurie Putz, Alain Mayné, Anne-Sophie Dincq
The indications for rigid bronchoscopy for interventional pulmonology have increased and include stent placements and transbronchial cryobiopsy procedures. The shared airway between anesthesiologist and pulmonologist and the open airway system, requiring specific ventilation techniques such as jet ventilation, need a good understanding of the procedure to reduce potentially harmful complications. Appropriate adjustment of the ventilator settings including pause pressure and peak inspiratory pressure reduces the risk of barotrauma...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27829946/double-stenting-for-malignant-oesophago-respiratory-fistula
#7
Janusz Włodarczyk, Jarosław Kużdżał
INTRODUCTION: The close anatomical relationship between the oesophagus and bronchial tree results in formation of an oesophago-respiratory fistula in a subset of patients with advanced oesophageal or lung cancer. In those patients stenting of both the oesophagus and tracheobronchial tree is a valid option of palliative treatment. AIM: To determine the effectiveness, tolerance, quality of life, safety and survival after double stenting procedures. MATERIAL AND METHODS: Retrospective analysis of a prospectively collected database was performed, concerning consecutive patients with oesophago-respiratory fistulas treated with double stenting...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/27824004/paclitaxel-drug-eluting-tracheal-stent-could-reduce-granulation-tissue-formation-in-a-canine-model
#8
Ting Wang, Jie Zhang, Juan Wang, Ying-Hua Pei, Xiao-Jian Qiu, Yu-Ling Wang
BACKGROUND: Currently available silicone and metallic stents for tracheal stenosis are associated with many problems. Granulation proliferation is one of the main complications. The present study aimed to evaluate the efficacy of paclitaxel drug-eluting tracheal stent in reducing granulation tissue formation in a canine model, as well as the pharmacokinetic features and safety profiles of the coated drug. METHODS: Eight beagles were randomly divided into a control group (bare-metal stent group, n = 4) and an experimental group (paclitaxel-eluting stent group, n = 4)...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27815921/bronchial-artery-aneurysm-suggested-to-be-caused-by-metalic-tracheal-stent-migration
#9
Kiyoshi Sato, Satoshi Fumimoto, Takehisa Fukada, Kaoru Ochi, Takayuki Kataoka, Yoshio Ichihashi, Hidetoshi Satomi, Takuya Morita, Nobuharu Hanaoka, Yoshikatsu Okada, Takahiro Katsumata
Occurrence of bronchial artery aneurysm is rare, and it has been detected in less than 1 % of all selective bronchial arteriography cases. Here, we present a case of a bronchial artery aneurysm caused by a tracheal stent migration. A 59-year-old man was operated on for esophageal cancer, where an esophageal-tracheal fistula occurred 1 week after operation. Surgical repair of the esophageal-tracheal fistula was performed using a muscle flap, but this not results in fistula closure. Consequently, a self-expanding covered metallic tracheal stent was implanted for rescue, and this resulted in fistula closure...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27777507/fully-covered-metallic-stents-for-the-treatment-of-benign-airway-stenosis
#10
Caroline Dahlqvist, Sebahat Ocak, Maximilien Gourdin, Anne Sophie Dincq, Laurie Putz, Jean-Paul d'Odémont
Introduction. We herein report our experience with new fully covered self-expanding metallic stents in the setting of inoperable recurrent benign tracheobronchial stenosis. Methods. Between May 2010 and July 2014, 21 Micro-Tech® FC-SEMS (Nanjing Co., Republic of Korea) were placed in our hospital in 16 patients for inoperable, recurrent (after dilatation), and symptomatic benign airway stenosis. Their medical files were retrospectively reviewed in December 2014, with focus on stent's tolerance and durability data...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27776743/open-airway-reconstruction-in-adults-outcomes-and-prognostic-factors
#11
Marianne Abouyared, Mikhaylo Szczupak, Eric Barbarite, Zoukaa B Sargi, David E Rosow
PURPOSE: The purpose was to assess the success of open tracheal resection and re-anastomosis for non-malignant tracheal stenosis in adults. Successful operations were defined as T-tube or tracheostomy-free status by 6months post-operatively. MATERIALS AND METHODS: Retrospective chart review was performed and data were recorded in a de-identified manner. The primary outcome was T-tube or tracheostomy-free status by 6months following tracheal resection. Clinical and demographic characteristics were evaluated as potential prognostic variables...
September 7, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27766714/clinical-significance-of-differentiating-post-intubation-and-post-tracheostomy-tracheal-stenosis
#12
Beomsu Shin, Kang Kim, Byeong-Ho Jeong, Jung Seop Eom, Won Jun Song, Hyung Koo Kang, Hojoong Kim
BACKGROUND AND OBJECTIVE: Post-intubation tracheal stenosis (PITS) and post-tracheostomy tracheal stenosis (PTTS) are serious complications in mechanically ventilated patients. Although the aetiologies and mechanisms of PITS and PTTS are quite different, little is known about the clinical impact of differentiating one from the other. METHODS: We retrospectively conducted a chart review of 117 patients with PITS and 88 patients with PTTS who were treated with interventional bronchoscopy at Samsung Medical Center between January 2004 and December 2013...
October 21, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27766409/laser-tracheobronchoplasty-a-novel-technique-for-the-treatment-of-symptomatic-tracheobronchomalacia
#13
Paul Castellanos, Manjunath Mk, Ihab Atallah
The management of tracheobronchomalacia is a very challenging problem with few treatment options. This study aims to evaluate the outcomes of a novel surgical treatment for membranous tracheobronchomalacia. A consecutive series of patients with tracheobronchomalacia were treated with two to three holmium laser scarring surgeries of the hyperdynamic tracheal and bronchial walls for the purpose of stiffening them through fibrosis. Patients filled out a Dyspnea Index questionnaire before and after treatment. Ten patients were treated for their tracheobronchomalacia with a mean age of 54 years...
October 20, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27751243/repair-of-large-airway-defects-with-bioprosthetic-materials
#14
Brooks V Udelsman, Jessica Eaton, Ashok Muniappan, Christopher R Morse, Cameron D Wright, Douglas J Mathisen
OBJECTIVE: Patients with complicated airway defects that exceed the limits of primary repair represent a challenging clinical problem and require alternative techniques for repair. The aim of this study was to evaluate bioprosthetic reconstruction of large tracheal and bronchial defects. METHODS: Retrospective chart review of patients treated at a single tertiary center from 2008 to 2015 who underwent repair of tracheal or bronchial defects with a bioprosthetic device, namely aortic homograft or acellular dermal matrix...
November 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27712036/in-vitro-evaluation-of-poly-lactic-co-glycolic-acid-polyisoprene-fibers-for-soft-tissue-engineering
#15
Douglas R Marques, Luís A L Dos Santos, Marie A O'Brien, Sarah H Cartmell, Julie E Gough
The polymeric blend of poly (lactic-co-glycolic acid) (PLGA) and polyisoprene (PI) has recently been explored for application as stents for tracheal stenosis and spring for the treatment of craniosynostosis. From the positive results presented in other biomedical applications comes the possibility of investigating the application of this material as scaffold for tissue engineering (TE), acquiring a deeper knowledge about the polymeric blend by exploring a new processing technique while attending to the most fundamental demands of TE scaffolds...
October 6, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27694536/laryngotracheal-stenosis-in-children-and-infants-with-neurological-disorders-management-and-outcome
#16
Richard Nicollas, Eric Moreddu, Claire Le Treut-Gay, Stéphane Roman, Julien Mancini, Jean-Michel Triglia
INTRODUCTION: The goal of this retrospective study is to compare the management and outcome of surgical treatment of laryngotracheal stenosis in children and infants with and without an associated neurological disorder. PATIENTS AND METHOD: In a series of children operated on for subglottic stenosis (SGS), patients with an associated neurological disorder were identified. The following criteria were compared in children with and without neurological disease: grade of stenosis, age, technique (Crico-Tracheal Resection (CTR), Laryngo-Tracheo-Plasty (LTP) in single and 2 stage, laser), analyzing duration, preoperative tracheostomy, decannulation rate, preoperative gastrostomy, and number of days in intensive care unit and in hospital...
December 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27670964/biodegradable-polydioxanone-stent-as-a-new-treatment-strategy-for-tracheal-stenosis-in-a-rabbit-model
#17
Insu Kawahara, Shigeru Ono, Kosaku Maeda
PURPOSE: Congenital tracheal stenosis (CTS) is a rare condition and difficult to treat. Slide tracheoplasty has unsatisfactory outcomes for severe neonatal symptomatic CTS. This study evaluated the use of biodegradable polydioxanone stents (BD stent) in a rabbit model of CTS. METHODS: Tracheal stenosis was induced in female Japanese white rabbits, 9-10weeks old, by direct scraping of the tracheal mucosa with a nylon brush following transverse incision of the trachea (control group, n=4)...
September 15, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27645990/a-novel-method-for-insertion-of-the-straight-metallic-tracheal-stent
#18
Kuruswamy Thurai Prasad, Babu Ram, Inderpaul Singh Sehgal, Sahajal Dhooria, Ritesh Agarwal
A straight metallic tracheal stent can be inserted either during flexible or rigid bronchoscopy. However, in patients with significant airway obstruction or those requiring tumor debulking, rigid bronchoscopy is the method of choice. A tracheoscope size 12 or larger is generally required for the introduction of the straight metallic tracheal stent. Herein, we describe a novel method that facilitates the introduction of the straight metallic tracheal stent through a size 8.5 tracheoscope by using the introducer tube of the silicone stent applicator...
October 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27641295/a-modified-technique-of-laryngotracheal-reconstruction-without-the-need-for-prolonged-postoperative-stenting
#19
Konrad Hoetzenecker, Thomas Schweiger, Imme Roesner, Matthias Leonhard, Gabriel Marta, Doris M Denk-Linnert, Berit Schneider-Stickler, Wolfgang Bigenzahn, Walter Klepetko
OBJECTIVES: Repair of laryngotracheal stenosis with pronounced side-to-side narrowing and involvement of the glottis is challenging and usually requires laryngotracheal reconstruction with rib cartilage interpositions. This technique, as first described by Couraud, needs prolonged postoperative stabilization with Montgomery T-tubes, imposing significant morbidity and discomfort on patients. We describe our initial experience with a modified laryngotracheal reconstruction technique that avoids the need for prolonged postoperative stenting...
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27608892/age-and-gender-related-changes-in-bronchial-tree-a-morphometric-study-with-multidedector-ct
#20
M Ulusoy, I I Uysal, A S Kıvrak, S Ozbek, A K Karabulut, Y Paksoy, N U Dogan
OBJECTIVE: The aims of this study are the identification of differences in the diameter, length, area and branching angles of the trachea and bronchi with gender and age, and the identification of trachea types by using MDCT images. PATIENTS AND METHODS: The thoracic MDCT images of 253 patients (0-74 years old, 142 male and 111 female) were evaluated. Tracheal diameter, tracheal cross-sectional area, diameter and length of bronchi, and several angles of the bronchial tree [e...
August 2016: European Review for Medical and Pharmacological Sciences
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